Last update
6/7/2026

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.1
Supplement Facts
Serving Size:  1 Capsule
Amount Per Serving
%DV
Thiamin (as thiamine hydrochloride)
25 mg
2,083%
Riboflavin (as riboflavin 5'-phosphate sodium)
20 mg
1,538%
Niacin (as inositol hexanicotinate and nicotinic acid)
95 mg NE
594%
Vitamin B6 (as pyridoxal 5'-phosphate)
20 mg
1,176%
Folate [as Quatrefolic® (6S)-5-methyltetrahydrofolate, glucosamine salt and calcium folinate]
680 mcg DFE (400 mcg)
170%
Vitamin B12 (as MECOBALACTIVE® methylcobalamin and adenosylcobalamin)
50 mcg
2,083%
Biotin
750 mcg
2,500%
Pantothenic Acid (as d-calcium pantothenate)
125 mg
2,500%
Choline (as choline bitartrate)
50 mg
9%
📅 Last updated:

Top Medical Research Studies

9
Panthenol mask improves skin barrier
We aimed to evaluate how a panthenol-enriched mask, specifically La Roche-Posay Mask Pro, performs in improving skin barriers for different types, such as dry sensitive, oily sensitive, and oily acne-prone skin.

Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.

The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Read More
7
A split-face study on 20 acne patients compared two treatments applied to opposite sides of the face. The right side received four intense pulsed light (IPL) sessions spaced two weeks apart, while the left side received topical nicotinamide 4% (vitamin B3) cream applied twice daily for two months.

Both treatments significantly improved inflammatory acne lesions. However, IPL delivered noticeably better results than the nicotinamide cream, with patients expressing greater satisfaction with the light-based approach. The findings suggest IPL is a safe and effective option for mild to moderate acne, particularly when other systemic treatments aren't suitable.
Read More

Most Useful Reviews

0
Reduced acne
This active ingredient is very effective, making my skin less susceptible to acne while adding vitality.
Read More
0
Caused acne
I stopped taking these due to the biotin causing me acne. It’s unfortunate as this is a fantastic brand.
Read More

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Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
  • All Researches
9
Panthenol mask improves skin barrier
We aimed to evaluate how a panthenol-enriched mask, specifically La Roche-Posay Mask Pro, performs in improving skin barriers for different types, such as dry sensitive, oily sensitive, and oily acne-prone skin.

Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.

The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Read More
7
A split-face study on 20 acne patients compared two treatments applied to opposite sides of the face. The right side received four intense pulsed light (IPL) sessions spaced two weeks apart, while the left side received topical nicotinamide 4% (vitamin B3) cream applied twice daily for two months.

Both treatments significantly improved inflammatory acne lesions. However, IPL delivered noticeably better results than the nicotinamide cream, with patients expressing greater satisfaction with the light-based approach. The findings suggest IPL is a safe and effective option for mild to moderate acne, particularly when other systemic treatments aren't suitable.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 2 Reviews
7.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
0
Reduced acne
This active ingredient is very effective, making my skin less susceptible to acne while adding vitality.
Read More
0
Caused acne
I stopped taking these due to the biotin causing me acne. It’s unfortunate as this is a fantastic brand.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Zhang X, Tao H, Deng Y, He X, Zhang Z, et al. Efficacy and safety of a panthenol-enriched mask for individuals with distinct impaired skin barrier subtypes. J Cosmet Dermatol. 2024;23:2109. 10.1111/jocd.16231
  2. Al-Sharnoby HA, Al-Bakary RH, Nassar SO, Mesbah RAM. The Efficacy of Intense Pulsed Light Versus Topical Nicotinamide 4% in Treatment of Acne Vulgaris. Photodermatol Photoimmunol Photomed. 2025;41:e70025. 10.1111/phpp.70025
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