We aimed to understand how vitamin D influences bone health and helps combat osteoporosis, a condition that weakens bones. In our study, we used various mouse models, including those that mimic a deficiency in active vitamin D. Through a range of advanced methods, we assessed how changes in vitamin D levels affected bone structure and metabolism.
The research revealed that insufficient vitamin D led to a drop in Sirt1, a gene that plays a crucial role in maintaining bone density. This lack of Sirt1 resulted in increased bone loss. However, when we boosted Sirt1 levels in bone stem cells, we observed a reversal in bone loss. This improvement happened because higher Sirt1 levels reduced oxidative stress, slowed down aging processes in bone cells, and enhanced new bone formation while curbing bone resorption.
Additionally, our findings indicated that vitamin D directly stimulates Sirt1 expression in these stem cells, which is vital for bone health. We also explored the effects of resveratrol, a natural compound known for activating Sirt1, and found it helped alleviate osteoporosis symptoms linked to vitamin D deficiency by enhancing the relationship between Sirt1 and another protein called PGC1α, which supports bone formation and energy metabolism.
This research underscores the importance of the vitamin D-Sirt1/PGC1α axis in bone metabolism, providing insight into how vitamin D can serve as a target for osteoporosis prevention and treatment.
Read More
7
Vitamin D and osteoporosis insight
Daily or intermittent vitamin D supplementation in patients with or at risk of osteoporosis: Position statement from the GRIO.
We explored the effects of vitamin D supplementation on osteoporosis, especially among individuals at risk for this condition. The Osteoporosis Research and Information Group (GRIO) highlighted the critical difference between daily and intermittent vitamin D dosing.
Current literature indicates that taking high doses of vitamin D intermittently, such as 60,000 IU a month, can actually elevate the chances of falls, fractures, and even premature death in some groups. Conversely, daily supplementation of 800-1000 IU, particularly alongside calcium, has been shown to reduce falls and non-vertebral fractures in the elderly who have a vitamin D deficiency.
Before anyone starts supplementing, it is crucial to measure their vitamin D levels to achieve a target concentration of 30 to 60 ng/mL. For those needing a quick boost in vitamin D levels—like patients showing symptoms of osteomalacia or those with critically low vitamin D—a starting loading dose followed by daily maintenance is the preferred approach. If daily options aren’t available, of course, a smaller intermittent dose can be a temporary solution until better options are accessible.
Read More
9
Probiotic support for osteoporosis treatment
increases serum vitamin D metabolite levels and modulates intestinal flora to alleviate osteoporosis in mice.
We explored how a specific probiotic strain, FSHHK13M1, affects vitamin D metabolism and osteoporosis in mice. Previous research pointed out that the gut microbiota plays a crucial role in vitamin D metabolism, which is especially relevant for older adults who tend to suffer from osteoporosis due to declining organ functions.
Our study demonstrated that treating the mice with FSHHK13M1 led to a significant increase in their serum levels of active vitamin D metabolites, particularly 1,25-dihydroxy vitamin D. This increase was linked to activation of important bone health pathways, helping to fortify bone structure and function.
Not only did we observe improvements in vitamin D levels, but the intervention also restored balance in the gut microbiota, which showed signs of imbalance in mice suffering from osteoporosis. The findings suggest that FSHHK13M1 could be a promising direction for improving bone health and reducing fracture risks in the elderly by enhancing vitamin D levels naturally.
Overall, this research highlights the potential of combining probiotics with vitamin D strategies for better management of osteoporosis, especially in older populations who often face challenges absorbing conventional treatments.
Read More
Most Useful Reviews
7.5
Prevents osteoporosis
Very good. It is D3 at a reasonable price, most suitable for children. Remember to take it after a meal for better absorption. It has no fishy smell and is not rejected by children. D3 aids calcium absorption. If you have doubts about growth, consult a doctor. I hope there will be more discounts in the future, as I will consider buying more. It promotes calcium and phosphorus absorption, prevents osteoporosis, and can be beneficial for the elderly.
Read More
7.5
Muscle strength improvements
Vitamin D receptors are present in striated muscle fibres, crucial for regulating calcium exchange in muscle tissue, directly impacting muscle contraction and relaxation. Deficiency leads to decreased muscle strength and balance issues. Vitamin D also prevents rickets in children, protects against osteoporosis in adults, and accelerates fracture healing. The quality is excellent, taste is neutral, size is comfortable, and the packaging is good.
Read More
7.5
Accelerates fracture healing
In infants, vitamin D prevents rickets, while in adolescents and adults, it prevents caries and protects against osteoporosis. It also accelerates the healing of fractures, safeguarding bone health effectively.
We explored how a specific probiotic strain, FSHHK13M1, affects vitamin D metabolism and osteoporosis in mice. Previous research pointed out that the gut microbiota plays a crucial role in vitamin D metabolism, which is especially relevant for older adults who tend to suffer from osteoporosis due to declining organ functions.
Our study demonstrated that treating the mice with FSHHK13M1 led to a significant increase in their serum levels of active vitamin D metabolites, particularly 1,25-dihydroxy vitamin D. This increase was linked to activation of important bone health pathways, helping to fortify bone structure and function.
Not only did we observe improvements in vitamin D levels, but the intervention also restored balance in the gut microbiota, which showed signs of imbalance in mice suffering from osteoporosis. The findings suggest that FSHHK13M1 could be a promising direction for improving bone health and reducing fracture risks in the elderly by enhancing vitamin D levels naturally.
Overall, this research highlights the potential of combining probiotics with vitamin D strategies for better management of osteoporosis, especially in older populations who often face challenges absorbing conventional treatments.
Read More
8
Vitamin D aids cancer treatment outcomes
A Systematic Review of Vitamin D Supplementation in Oncology: Chance of Science or Effectiveness?
We explored the role of vitamin D (VD) supplementation in supporting cancer patients undergoing chemotherapy and radiotherapy, particularly regarding its effects on osteoporosis. The aim was to sift through scientific evidence to understand how vitamin D influences not just bone health but also alleviates the side effects of demanding cancer treatments.
Our findings indicated that adequate levels of VD are important for maintaining bone density in patients, especially those receiving preoperative chemoradiotherapy. Some studies showed that vitamin D supplementation could lessen certain severe side effects, like fatigue and nausea, often experienced during cancer treatments.
However, the evidence regarding the isolated effects of vitamin D on osteoporosis, specifically, was limited due to the varied designs of the included studies. Despite these challenges, it seems clear that vitamin D plays a valuable role in managing bone health and reducing treatment-related complications.
Read More
8
Vitamin D improves bone health
Chronically increased osteoclastogenesis in adult celiac disease patients does not hinder improvement in bone health induced by gluten-free diet: Role of vitamin D, OPG and IL-6.
We investigated how vitamin D affects bone health, particularly focusing on individuals with celiac disease (CeD). Our study aimed to uncover the role of vitamin D alongside other key proteins in bone metabolism as patients transitioned to a gluten-free diet (GFD).
Through a careful examination, we observed notable changes in bone mineral density (BMD) among those who adhered to the GFD. Specifically, we found that patients after GFD treatment had improved serum levels of vitamin D, which correlated with healthier bone outcomes, including increased BMD and reduced markers of bone turnover.
Interestingly, even though the capacity for osteoclast formation—a type of cell responsible for bone resorption—remained elevated in these patients, their bone health still improved. This suggests that, while vitamin D plays a crucial role in bone strength, the connection between osteoclast activity and overall bone health might change with proper dietary management.
Our findings emphasized how vital vitamin D is for bone health, particularly in the context of managing celiac disease, where absorption can be compromised. Ultimately, we learned that a gluten-free lifestyle brings significant benefits for bone density, along with the supportive actions of vitamin D.
Read More
8
Vitamin D's role in fracture risk
Association Between 25-hydroxyvitamin D Status and New Vertebral Fractures Post Percutaneous Vertebral Augmentation in Patients During Postmenopause: A Retrospective Case-control Study.
We examined the relationship between vitamin D levels and the risk of new vertebral fractures after patients underwent a specific spine procedure called percutaneous vertebral augmentation. Our focus was on postmenopausal women aged 50 and above, who often face an increased risk of fractures due to osteoporosis.
In this retrospective study, we categorized patients into groups based on whether they experienced new osteoporotic vertebral fractures or not. Our analysis revealed that low levels of serum 25-hydroxyvitamin D are an independent risk factor for these new fractures.
This suggests that maintaining adequate vitamin D levels could be crucial for individuals recovering from this type of spinal surgery. By ensuring active vitamin D supplementation after the procedure, patients may significantly lower their chances of future osteoporotic vertebral fractures, promoting better recovery and overall health.
Read More
8
Vitamin D's impact on osteoporosis
The Vitamin D-Sirt1/PGC1α Axis Regulates Bone Metabolism and Counteracts Osteoporosis.
We aimed to understand how vitamin D influences bone health and helps combat osteoporosis, a condition that weakens bones. In our study, we used various mouse models, including those that mimic a deficiency in active vitamin D. Through a range of advanced methods, we assessed how changes in vitamin D levels affected bone structure and metabolism.
The research revealed that insufficient vitamin D led to a drop in Sirt1, a gene that plays a crucial role in maintaining bone density. This lack of Sirt1 resulted in increased bone loss. However, when we boosted Sirt1 levels in bone stem cells, we observed a reversal in bone loss. This improvement happened because higher Sirt1 levels reduced oxidative stress, slowed down aging processes in bone cells, and enhanced new bone formation while curbing bone resorption.
Additionally, our findings indicated that vitamin D directly stimulates Sirt1 expression in these stem cells, which is vital for bone health. We also explored the effects of resveratrol, a natural compound known for activating Sirt1, and found it helped alleviate osteoporosis symptoms linked to vitamin D deficiency by enhancing the relationship between Sirt1 and another protein called PGC1α, which supports bone formation and energy metabolism.
This research underscores the importance of the vitamin D-Sirt1/PGC1α axis in bone metabolism, providing insight into how vitamin D can serve as a target for osteoporosis prevention and treatment.
Very good. It is D3 at a reasonable price, most suitable for children. Remember to take it after a meal for better absorption. It has no fishy smell and is not rejected by children. D3 aids calcium absorption. If you have doubts about growth, consult a doctor. I hope there will be more discounts in the future, as I will consider buying more. It promotes calcium and phosphorus absorption, prevents osteoporosis, and can be beneficial for the elderly.
Read More
7.5
Muscle strength improvements
Vitamin D receptors are present in striated muscle fibres, crucial for regulating calcium exchange in muscle tissue, directly impacting muscle contraction and relaxation. Deficiency leads to decreased muscle strength and balance issues. Vitamin D also prevents rickets in children, protects against osteoporosis in adults, and accelerates fracture healing. The quality is excellent, taste is neutral, size is comfortable, and the packaging is good.
Read More
7.5
Accelerates fracture healing
In infants, vitamin D prevents rickets, while in adolescents and adults, it prevents caries and protects against osteoporosis. It also accelerates the healing of fractures, safeguarding bone health effectively.
Read More
7.5
Prevents rickets
Excellent composition without unnecessary components—only vitamin D and an oil base. I have given it to my child since birth. Vitamin D is essential in children to prevent rickets. In adolescents and adults, it also combats caries, helps protect against osteoporosis, and accelerates fracture healing.
Read More
7.5
Boosts overall health
Vitamin D3 is vital for maintaining bone quality, assisting the body in absorbing calcium and phosphorus. It reduces the risk of diseases, including osteoporosis and enhances immunity. Proper vitamin D levels strengthen muscles, improve mood, and elevate energy levels. A deficiency can result in reduced bone strength, poor health, and weakened immunity.
Read More
Frequently Asked Questions
Osteoporosis is a medical condition characterized by weakened bones, making them fragile and more prone to fractures. This condition occurs when the body loses too much bone mass, doesn't make enough bone, or a combination of both. As bones lose density, they can break more easily, often as a result of minor falls or injury. Osteoporosis is often referred to as a "silent disease" because bone loss occurs without any symptoms until a fracture occurs, often in the hip, spine, or wrist.
Risk factors for developing osteoporosis include age, gender (it’s more common in women), family history, low body weight, and certain medical conditions and medications. Lifestyle choices such as smoking, excessive alcohol consumption, and a diet low in calcium and vitamin D can also contribute to bone loss. Regular weight-bearing exercise, ensuring adequate nutrition, and, in some cases, medications can help prevent or manage osteoporosis. If you believe you may be at risk, it is important to consult with a healthcare professional for appropriate screening and intervention options.
Children's Vitamin D is a dietary supplement specifically formulated to support the health and development of children. Vitamin D is crucial for maintaining healthy bones and teeth, and it plays an essential role in the functioning of the immune system. Young children, especially those who may have limited sun exposure or dietary intake of vitamin D, are often recommended to take these supplements to ensure they receive adequate levels for optimal growth and development.
Typically, children's vitamin D supplements come in various forms such as chewable tablets, gummies, or liquid drops, making them more palatable for younger audiences. The most common form is vitamin D3 (cholecalciferol), which is considered more effective in raising vitamin D levels in the body than D2 (ergocalciferol). It's essential for parents to consult with a pediatrician before starting any supplement to determine the right dosage based on individual health needs and lifestyle factors. Proper intake of vitamin D not only supports bone health but also has been linked to other health benefits, such as improved mood and immune response, making it a valuable addition to children's wellness routines.
Vitamin D plays a crucial role in bone health, and its importance extends even to children, as it helps the body absorb calcium, which is essential for developing strong bones. Adequate vitamin D levels during childhood are particularly critical since the amount of bone mass acquired during these formative years can influence the risk of osteoporosis later in life. While Children's Vitamin D supplements can help ensure that kids get the recommended amount for optimal bone development, they are just one piece of the puzzle.
That said, if you're specifically concerned about osteoporosis, it's important to note that while Children's Vitamin D supports overall bone health, it is not a direct treatment for existing osteoporosis in adults or children. A comprehensive approach that includes a balanced diet rich in calcium, regular physical activity, and healthful lifestyle choices is essential for optimal bone health and reducing osteoporosis risk. Always consult a healthcare provider for personalized advice regarding supplementation and bone health.
Based on user reviews, the effectiveness of vitamin D3 supplements for osteoporosis may become evident within a few weeks of consistent use. Several reviews highlight the crucial role of vitamin D in promoting calcium absorption and maintaining bone health, particularly in older adults Read Review. Users appreciate the combination of vitamin D3 in their regimen, noting that it aids in reducing the risk of osteoporosis and accelerates fracture healing Read Review.
While exact timelines for seeing results can vary depending on individual circumstances, many users report feeling the benefits relatively quickly, especially when used alongside a balanced diet and regular exercise. Maintaining adequate vitamin D levels is essential, as deficiency can lead to weakened bones and other health issues Read Review. Consistent supplementation can lead to improvements in bone density and strength over time.
The role of vitamin D in managing osteoporosis is supported by several studies, highlighting its significant impact on bone health. Research indicates that adequate vitamin D levels can improve bone density, especially among populations at risk of fractures, such as postmenopausal women and those undergoing specific medical treatments. For instance, a study found that maintaining proper serum vitamin D levels can lower the risk of new osteoporotic fractures after spine surgery in postmenopausal women, emphasizing the necessity of adequate supplementation for optimal recovery and bone health [6]. Furthermore, vitamin D supplementation alongside calcium has been associated with reduced falls and fractures in the elderly, suggesting that combining these supplements may be a strategic approach for osteoporosis management [4].
However, the relationship is not without its complexities. Some research notes that while vitamin D is essential, the effects of supplementation can vary based on dosage and individual circumstances. High doses of vitamin D taken intermittently might even elevate risks for certain individuals, such as increasing the likelihood of falls [4]. Additionally, while certain studies focus on vitamin D’s role alongside other treatments, such as calcium or probiotics, the isolated effects of vitamin D on osteoporosis remain a topic of ongoing research, indicating that while it can support bone health, optimal strategies may require a multifaceted approach [2]. Overall, there's a strong scientific basis for vitamin D's involvement in osteoporosis management but also a need for tailored approaches based on individual health profiles and existing conditions.
Based on user reviews, many individuals report significant improvements in health and well-being after incorporating vitamin D3 supplements into their routines. Users note enhanced calcium and phosphorus absorption, which is crucial for maintaining strong bones and preventing conditions such as osteoporosis. For instance, one review highlights the importance of vitamin D in safeguarding bone health for both children and adults, especially in accelerating fracture healing and combating caries Read Review. Another user emphasizes that consistent use results in better muscle strength and balance, further supporting overall physical functioning Read Review.
Additionally, users often mention positive changes in mood and energy levels, suggesting that vitamin D3 may also contribute to enhanced overall vitality. One reviewer specifically noted improved emotional well-being alongside the physical benefits of stronger bones and muscles Read Review. It's important to keep in mind that individual results can vary based on factors such as diet, lifestyle, and existing health conditions, but the collective experiences shared by users indicate a worthwhile investment in vitamin D3 supplementation.
Based on user reviews, many individuals report that combining vitamin D3 with other supplements enhances its effectiveness in managing osteoporosis. Users emphasize the critical role of vitamin D3 in promoting calcium absorption, crucial for maintaining bone density and preventing osteoporosis. For instance, one user mentioned that taking vitamin D after meals optimizes absorption, highlighting its collaborative nature with calcium and phosphorus in bone health Read Review. Additionally, users note that consistent use of vitamin D3 not only protects against osteoporosis but also accelerates fracture healing and improves overall muscle strength and balance Read Review.
Furthermore, it appears that users find particular value in integrating vitamin D3 with a broader health regimen, suggesting that this combination leads to better health outcomes. Many reviews highlight the importance of maintaining adequate vitamin D levels to prevent rickets in children and to protect against osteoporosis in older adults. The general consensus indicates that pairing vitamin D3 with calcium supplementation may yield substantial benefits for bone health Read Review. Overall, user experiences suggest that a strategic approach to supplementation, incorporating vitamin D3, can significantly impact bone strength and overall vitality.
Users report that Vitamin D, particularly D3, plays a crucial role in maintaining bone health and preventing conditions like osteoporosis in both children and adults. Reviewers emphasize the importance of ensuring that children receive an adequate dose, ideally after meals to enhance absorption. The consensus suggests that these supplements not only aid in the absorption of calcium and phosphorus but also mitigate the risks associated with bone health degradation as individuals age. For example, one user highlighted that "D3 aids calcium absorption... promotes calcium and phosphorus absorption, prevents osteoporosis" Read Review.
While specific dosages weren't frequently mentioned, users consistently noted the need for Vitamin D in preventing deficiencies that could lead to decreased muscle strength and balance issues, as well as prevent rickets in children and protect against osteoporosis in adults Read Review. Overall, users suggest consulting a healthcare professional for personalized dosing, especially if there are concerns about a child's growth or bone health Read Review.
7.5
Prevents osteoporosis
Very good. It is D3 at a reasonable price, most suitable for children. Remember to take it after a meal for better absorption. It has no fishy smell and is not rejected by children. D3 aids calcium absorption. If you have doubts about growth, consult a doctor. I hope there will be more discounts in the future, as I will consider buying more. It promotes calcium and phosphorus absorption, prevents osteoporosis, and can be beneficial for the elderly.
7.5
Accelerates fracture healing
In infants, vitamin D prevents rickets, while in adolescents and adults, it prevents caries and protects against osteoporosis. It also accelerates the healing of fractures, safeguarding bone health effectively.
7.5
Boosts overall health
Vitamin D3 is vital for maintaining bone quality, assisting the body in absorbing calcium and phosphorus. It reduces the risk of diseases, including osteoporosis and enhances immunity. Proper vitamin D levels strengthen muscles, improve mood, and elevate energy levels. A deficiency can result in reduced bone strength, poor health, and weakened immunity.
7.5
Muscle strength improvements
Vitamin D receptors are present in striated muscle fibres, crucial for regulating calcium exchange in muscle tissue, directly impacting muscle contraction and relaxation. Deficiency leads to decreased muscle strength and balance issues. Vitamin D also prevents rickets in children, protects against osteoporosis in adults, and accelerates fracture healing. The quality is excellent, taste is neutral, size is comfortable, and the packaging is good.
8
Vitamin D's role in fracture risk
Association Between 25-hydroxyvitamin D Status and New Vertebral Fractures Post Percutaneous Vertebral Augmentation in Patients During Postmenopause: A Retrospective Case-control Study.
We examined the relationship between vitamin D levels and the risk of new vertebral fractures after patients underwent a specific spine procedure called percutaneous vertebral augmentation. Our focus was on postmenopausal women aged 50 and above, who often face an increased risk of fractures due to osteoporosis.
In this retrospective study, we categorized patients into groups based on whether they experienced new osteoporotic vertebral fractures or not. Our analysis revealed that low levels of serum 25-hydroxyvitamin D are an independent risk factor for these new fractures.
This suggests that maintaining adequate vitamin D levels could be crucial for individuals recovering from this type of spinal surgery. By ensuring active vitamin D supplementation after the procedure, patients may significantly lower their chances of future osteoporotic vertebral fractures, promoting better recovery and overall health.
7
Vitamin D and osteoporosis insight
Daily or intermittent vitamin D supplementation in patients with or at risk of osteoporosis: Position statement from the GRIO.
We explored the effects of vitamin D supplementation on osteoporosis, especially among individuals at risk for this condition. The Osteoporosis Research and Information Group (GRIO) highlighted the critical difference between daily and intermittent vitamin D dosing.
Current literature indicates that taking high doses of vitamin D intermittently, such as 60,000 IU a month, can actually elevate the chances of falls, fractures, and even premature death in some groups. Conversely, daily supplementation of 800-1000 IU, particularly alongside calcium, has been shown to reduce falls and non-vertebral fractures in the elderly who have a vitamin D deficiency.
Before anyone starts supplementing, it is crucial to measure their vitamin D levels to achieve a target concentration of 30 to 60 ng/mL. For those needing a quick boost in vitamin D levels—like patients showing symptoms of osteomalacia or those with critically low vitamin D—a starting loading dose followed by daily maintenance is the preferred approach. If daily options aren’t available, of course, a smaller intermittent dose can be a temporary solution until better options are accessible.
9
Probiotic support for osteoporosis treatment
increases serum vitamin D metabolite levels and modulates intestinal flora to alleviate osteoporosis in mice.
We explored how a specific probiotic strain, FSHHK13M1, affects vitamin D metabolism and osteoporosis in mice. Previous research pointed out that the gut microbiota plays a crucial role in vitamin D metabolism, which is especially relevant for older adults who tend to suffer from osteoporosis due to declining organ functions.
Our study demonstrated that treating the mice with FSHHK13M1 led to a significant increase in their serum levels of active vitamin D metabolites, particularly 1,25-dihydroxy vitamin D. This increase was linked to activation of important bone health pathways, helping to fortify bone structure and function.
Not only did we observe improvements in vitamin D levels, but the intervention also restored balance in the gut microbiota, which showed signs of imbalance in mice suffering from osteoporosis. The findings suggest that FSHHK13M1 could be a promising direction for improving bone health and reducing fracture risks in the elderly by enhancing vitamin D levels naturally.
Overall, this research highlights the potential of combining probiotics with vitamin D strategies for better management of osteoporosis, especially in older populations who often face challenges absorbing conventional treatments.
References
Afonso ML, Capelas ML, Pimenta NM, Santos T, Mäkitie A, et al. A Systematic Review of Vitamin D Supplementation in Oncology: Chance of Science or Effectiveness?. Nutrients. 2025;17. doi:10.3390/nu17040634
Wang H, Tian G, Pei Z, Yu X, Wang Y, et al. increases serum vitamin D metabolite levels and modulates intestinal flora to alleviate osteoporosis in mice. mSphere. 2025. doi:10.1128/msphere.01039-24
Skubica P, Hoffmanova I, Dankova P. Chronically increased osteoclastogenesis in adult celiac disease patients does not hinder improvement in bone health induced by gluten-free diet: Role of vitamin D, OPG and IL-6. J Nutr Biochem. 2025. doi:10.1016/j.jnutbio.2025.109871
Pickering ME, Souberbielle JC, Boutten A, Breuil V, Briot K, et al. Daily or intermittent vitamin D supplementation in patients with or at risk of osteoporosis: Position statement from the GRIO. Joint Bone Spine. 2025;92:105858. doi:10.1016/j.jbspin.2025.105858
Shi L, Bao Y, Deng X, Xu X, Hu J. Association between calcium and vitamin D supplementation and increased risk of kidney stone formation in patients with osteoporosis in Southwest China: a cross-sectional study. BMJ Open. 2025;15:e092901. doi:10.1136/bmjopen-2024-092901
Zhang SB, Yang J, Xu HW, Yi YY, Ren CX, et al. Association Between 25-hydroxyvitamin D Status and New Vertebral Fractures Post Percutaneous Vertebral Augmentation in Patients During Postmenopause: A Retrospective Case-control Study. Pain Physician. 2025;28:E31.
Yang C, Chen L, Guo X, Sun H, Miao D. The Vitamin D-Sirt1/PGC1α Axis Regulates Bone Metabolism and Counteracts Osteoporosis. J Orthop Translat. 2025;50:211. doi:10.1016/j.jot.2024.10.011
Kuwabara N, Kanda J, Sato S, Nakagawa S. Impact of Daily High Ergosterol Intake for 14 Weeks in Ovariectomized Rats on Cholesterol and Vitamin D Biosynthesis Pathways. Biol Pharm Bull. 2025;48:39. doi:10.1248/bpb.b24-00536
McCarrison S, Abdelrahman S, Quinlivan R, Keen R, Wong SC. Pharmacological and non-pharmacological therapies for prevention and treatment of osteoporosis in Duchenne Muscular Dystrophy: A systematic review. Bone. 2025;193:117410. doi:10.1016/j.bone.2025.117410
Ma M, Zhang Y, Liu J, Tian C, Duan Z, et al. Associations of the serum 25-hydroxyvitamin D with mortality among patients in osteopenia or osteoporosis. Bone. 2025. doi:10.1016/j.bone.2025.117408