Fiber
9.5
Improves fertility
Most Useful Review
A good dose of Vitamin D is crucial. I’m an endocrinologist and assert that it's a hormone rather than a vitamin. Testing for Vitamin D levels before supplementation is essential. The optimal level should be above 65 ng/ml, and dosages can be higher without adverse reactions. It's evident that Vitamin D enhances fertility in men and women, boosts mood, and helps prevent osteoporosis.
9.5
Effective for calcium absorption
Most Useful Review
Two vitamins in one! This vitamin K2 combined with vitamin D3 is excellent for calcium absorption. I purchased it for my 9-year-old with dental issues. After a month, there was significant improvement in his teeth's condition. This product is highly recommended for anyone dealing with osteoporosis or dental problems.
Multivitamins
9.5
Pain relief
Most Useful Review
Working!!! I purchased this for a family member suffering from third degree osteoporosis in the hip joints. Remarkably, after just three days, they felt lighter and experienced pain relief. I found the same product being used by a friend, whose knee was in poor condition. After using this for several years, they are now active again. My trust in this product comes from a relative, sceptical of supplements, who found it effective for treating vertebral hernias. In conclusion, it's effective for injuries and musculoskeletal disorders.
9.5
Pain relief noted
Most Useful Review
Fast delivery and excellent quality. This drug is a panacea for me! It helps regulate my cycle, makes my skin glow, and reduces hair loss. Omega-3s prevent osteoporosis, maintain joint health, and alleviate pain during flare-ups. They combat bone mass loss, reduce inflammation, and slow cartilage destruction in arthrosis.
L Lysine
8
NSD2 inhibition may reduce osteoporosis
NSD2-mediated H3K36me2 exacerbates osteoporosis via activation of hoxa2 in bone marrow mesenchymal stem cells.
Most Relevant Research
We explored the connection between NSD2 and bone health, specifically how it affects bone marrow stem cells in osteoporosis. By using advanced techniques, we found that NSD2 inhibits the growth of these cells, which is crucial for healthy bones.
In animal models of osteoporosis, blocking NSD2 not only promoted stem cell differentiation but also helped prevent bone loss. Our findings suggest that targeting NSD2 could be a new way to treat osteoporosis and improve bone health.
In animal models of osteoporosis, blocking NSD2 not only promoted stem cell differentiation but also helped prevent bone loss. Our findings suggest that targeting NSD2 could be a new way to treat osteoporosis and improve bone health.
9.5
Prevents osteoporosis
Most Useful Review
Now Foods L-Lysine 500 mg is crucial for health. It aids immunity and helps prevent and treat yeast, fungal infections, and herpes due to its role in collagen synthesis. It's essential for calcium absorption, which is vital in preventing osteoporosis.
Vitamins
8
Vitamin D aids cancer treatment outcomes
A Systematic Review of Vitamin D Supplementation in Oncology: Chance of Science or Effectiveness?
Most Relevant Research
We explored the role of vitamin D (VD) supplementation in supporting cancer patients undergoing chemotherapy and radiotherapy, particularly regarding its effects on osteoporosis. The aim was to sift through scientific evidence to understand how vitamin D influences not just bone health but also alleviates the side effects of demanding cancer treatments.
Our findings indicated that adequate levels of VD are important for maintaining bone density in patients, especially those receiving preoperative chemoradiotherapy. Some studies showed that vitamin D supplementation could lessen certain severe side effects, like fatigue and nausea, often experienced during cancer treatments.
However, the evidence regarding the isolated effects of vitamin D on osteoporosis, specifically, was limited due to the varied designs of the included studies. Despite these challenges, it seems clear that vitamin D plays a valuable role in managing bone health and reducing treatment-related complications.
Our findings indicated that adequate levels of VD are important for maintaining bone density in patients, especially those receiving preoperative chemoradiotherapy. Some studies showed that vitamin D supplementation could lessen certain severe side effects, like fatigue and nausea, often experienced during cancer treatments.
However, the evidence regarding the isolated effects of vitamin D on osteoporosis, specifically, was limited due to the varied designs of the included studies. Despite these challenges, it seems clear that vitamin D plays a valuable role in managing bone health and reducing treatment-related complications.
9.5
Effective for calcium absorption
Most Useful Review
Two vitamins in one! This vitamin K2 combined with vitamin D3 is excellent for calcium absorption. I purchased it for my 9-year-old with dental issues. After a month, there was significant improvement in his teeth's condition. This product is highly recommended for anyone dealing with osteoporosis or dental problems.
Nattokinase
9.5
High-quality supplement
Most Useful Review
Nattokinase, discovered in Japan, is a potent enzyme from natto known for improving blood fluidity and preventing osteoporosis, strokes, and heart diseases. The Japanese greatly value traditional soy products, leading to their longevity. This quality supplement is an excellent alternative to aspirin for maintaining healthy blood density.
8.8
Improves osteoporosis treatment
Most Useful Review
Nattokinase is an incredibly beneficial enzyme that helps to normalise blood circulation and blood density. It is particularly effective for addressing osteoporosis and preventing strokes and heart attacks. I have noticed that my blood flow has improved significantly since I started taking it, and it has other positive effects like enhancing immunity and lowering cholesterol. This high-quality enzyme is an excellent alternative to aspirin.
Vitamin D
8
Vitamin D aids cancer treatment outcomes
A Systematic Review of Vitamin D Supplementation in Oncology: Chance of Science or Effectiveness?
Most Relevant Research
We explored the role of vitamin D (VD) supplementation in supporting cancer patients undergoing chemotherapy and radiotherapy, particularly regarding its effects on osteoporosis. The aim was to sift through scientific evidence to understand how vitamin D influences not just bone health but also alleviates the side effects of demanding cancer treatments.
Our findings indicated that adequate levels of VD are important for maintaining bone density in patients, especially those receiving preoperative chemoradiotherapy. Some studies showed that vitamin D supplementation could lessen certain severe side effects, like fatigue and nausea, often experienced during cancer treatments.
However, the evidence regarding the isolated effects of vitamin D on osteoporosis, specifically, was limited due to the varied designs of the included studies. Despite these challenges, it seems clear that vitamin D plays a valuable role in managing bone health and reducing treatment-related complications.
Our findings indicated that adequate levels of VD are important for maintaining bone density in patients, especially those receiving preoperative chemoradiotherapy. Some studies showed that vitamin D supplementation could lessen certain severe side effects, like fatigue and nausea, often experienced during cancer treatments.
However, the evidence regarding the isolated effects of vitamin D on osteoporosis, specifically, was limited due to the varied designs of the included studies. Despite these challenges, it seems clear that vitamin D plays a valuable role in managing bone health and reducing treatment-related complications.
9.5
Improves fertility
Most Useful Review
A good dose of Vitamin D is crucial. I’m an endocrinologist and assert that it's a hormone rather than a vitamin. Testing for Vitamin D levels before supplementation is essential. The optimal level should be above 65 ng/ml, and dosages can be higher without adverse reactions. It's evident that Vitamin D enhances fertility in men and women, boosts mood, and helps prevent osteoporosis.
Selenium
9.5
Supports fertility
Most Useful Review
This wonderful product provides essential elements for the body, improving fertility and aiding in weight loss. It also promotes hair growth and is beneficial for osteoporosis. Overall, it is a fantastic product and represents great value for the price.
8.8
Reduced fracture risk
Most Useful Review
Symptoms of selenium deficiency can include muscle weakness and pain, inflammation, increased fragility of red blood cells, and degeneration of the pancreas. This micronutrient is crucial for women, as it decreases osteoporosis risk during postmenopause. Additionally, it aids in hormone production, preventing dry mucous membranes, and is vital for pregnancy, supporting embryo implantation and placental development.
Potassium
9.5
Supports bone health
Most Useful Review
I believe potassium citrate is an excellent supplement that promotes urinary tract health and lowers the risk of kidney stones. It enhances electrolyte balance and reduces dehydration risk, while also improving bone health and potentially diminishing the risk of osteoporosis. Overall, I find potassium citrate a worthwhile choice for enhancing health.
8.8
Reduced osteoporosis risk
Most Useful Review
Potassium is an essential trace element that greatly diminishes the risk of swelling and stimulates enzyme production. Many people consume excessive salt while not getting enough potassium, leading to a deficiency. High potassium levels in the blood are associated with a significantly reduced risk of stroke and high blood pressure. Adequate potassium intake is also linked to better bone density and reduced osteoporosis risk.
Quercetin
9.5
Obvious effects noted
Most Useful Review
It has a noticeable effect on my mother's osteoporosis.
9.5
Improves multiple health aspects
Most Useful Review
Quercetin enhances kidney function, promotes heart health, prevents cancer, combats ageing, treats osteoporosis of the bones, extends life, and delays the onset of old age. I take it with resveratrol and coenzyme as antioxidants.
Boron
9.5
Improves bone strength
Most Useful Review
Boron, derived from organo-boron glycine by NOW Foods, supports bone strength and influences the metabolism of calcium, magnesium, and phosphorus. While boron deficiency is rare, it can contribute to osteoporosis and other health issues. I am pleased with this supplement and recommend it.
9.5
Positive bone support
Most Useful Review
I found boron capsules of 3 mg beneficial for bone health. Boron aids in maintaining bone structure and is especially helpful for those with osteoporosis or at risk. It also enhances calcium metabolism and hormonal balance. My experience has been positive with no side effects, but individual reactions can vary. Consulting a physician is advised.
Magnesium
9
Magnesium's role in osteoporosis
Relationship between multi-nutrient intake and bone loss and osteoporosis in U.S. adults: Findings from NHANES.
Most Relevant Research
We examined how dietary intake of magnesium, along with potassium and sodium, influences bone health, specifically focusing on osteoporosis and bone mineral density (BMD) in adults across the U.S. Our analysis was based on data from the National Health and Nutrition Examination Surveys, which spanned from 2005 to 2018, involving over 10,000 participants.
The findings revealed a positive association between higher dietary intake of potassium, magnesium, and sodium and improved BMD of the femur. This means that those who consumed more of these nutrients tended to have stronger bones. Additionally, we observed that a higher intake of these minerals was linked to a lower occurrence of osteopenia and osteoporosis.
Our study highlights how magnesium, when part of a broader nutrient intake that includes potassium and sodium, could play a significant role in maintaining bone health. While our research points to a beneficial relationship, more targeted studies are needed to definitively isolate the effects of magnesium alone on osteoporosis. Overall, this reinforces the importance of a balanced diet for bone health.
The findings revealed a positive association between higher dietary intake of potassium, magnesium, and sodium and improved BMD of the femur. This means that those who consumed more of these nutrients tended to have stronger bones. Additionally, we observed that a higher intake of these minerals was linked to a lower occurrence of osteopenia and osteoporosis.
Our study highlights how magnesium, when part of a broader nutrient intake that includes potassium and sodium, could play a significant role in maintaining bone health. While our research points to a beneficial relationship, more targeted studies are needed to definitively isolate the effects of magnesium alone on osteoporosis. Overall, this reinforces the importance of a balanced diet for bone health.
9.5
Promotes strong bones
Most Useful Review
After researching magnesium's role in osteoporosis, I started taking two 200mg tablets daily. They are cheap and effective, with no digestive issues. As someone training for a demanding mountain walking challenge at seventy, I recommend these for anyone wanting to maintain their health, especially in later life.
Resveratrol
8.8
Benefits osteoporosis treatment
Most Useful Review
Resveratrol is a dietary supplement that helps block tumour cell proliferation and reduces the risk of osteoporosis, particularly during menopause. It also stimulates collagen synthesis and may significantly lower cardiovascular disease risks. It is a powerful antioxidant, more effective than vitamin E. The packaging was excellent and undamaged.
8.8
Supports osteoporosis prevention
Most Useful Review
This product is effective for maintaining youth, especially for menopausal women. It reduces the risk of osteoporosis and promotes collagen synthesis.
Bone Formulas
9
Zuogui Pills improve osteoporosis outcomes
Zuogui Pills alleviate iron overload-induced osteoporosis by attenuating ROS-mediated osteoblast apoptosis via the PI3K-AKT pathway and mitigating mitochondrial damage.
Most Relevant Research
We investigated how Zuogui Pills (ZGP), an herbal formula used in Traditional Chinese Medicine, can help with osteoporosis caused by excessive iron. Our study utilized both mouse models and osteoblast cells to examine its effects.
Through detailed experiments, we noted that ZGP has strong antioxidant and anti-apoptotic properties. It works by engaging the PI3K/AKT pathway, reducing oxidative stress, and improving bone health. These results suggest that ZGP may be a valuable treatment option for osteoporosis linked to iron overload.
Through detailed experiments, we noted that ZGP has strong antioxidant and anti-apoptotic properties. It works by engaging the PI3K/AKT pathway, reducing oxidative stress, and improving bone health. These results suggest that ZGP may be a valuable treatment option for osteoporosis linked to iron overload.
9.5
Improved bone density
Most Useful Review
This product has aided my bone density after a year of use. I'm continuing to take it to improve the fourth area in my scan. In the three areas that improved, I've transitioned from osteoporosis to osteopenia!
Biotin
8.8
Vitamin D3 benefits
Most Useful Review
With a deficiency of vitamin D3 in women, the risk of various genitourinary diseases increases. During pregnancy, vitamin D3 aids calcium-phosphorus metabolism for a healthy gestation. Following menopause, the risk of osteoporosis significantly rises due to low estrogen. I took biotin for my hair, nails, and skin, and after one jar, I noticed a marked improvement.
8.8
Prevents osteoporosis
Most Useful Review
It effectively prevents osteoporosis and balances immunity. I found it very beneficial and will certainly purchase it again!
Collagen Supplements
9.5
Beneficial for elderly
Most Useful Review
This product does wonders for my mum’s osteoporosis. She has experienced positive effects since taking it.
8.8
His back pain reduced
Most Useful Review
My husband has osteoporosis and after starting this treatment, he feels significantly better. He reports that his back pain has decreased substantially.
Pumpkin Seeds Pepitas
9
Protein complex enhances bone health
A calcium-loaded complex based on Antarctic krill protein and supplemented with pectin promotes calcium absorption and bone health.
Most Relevant Research
We investigated how a unique protein complex, derived from Antarctic krill and enriched with pectin, influences calcium absorption and bone health, especially in the context of osteoporosis. Using a calcium-deficient mouse model, we assessed the effects of this complex, known as P + Ca + HMP, on calcium intake and bone structure.
Our findings were impressive: chronic low calcium levels led to reduced calcium absorption and weakened bone architecture. However, the P + Ca + HMP complex turned the situation around. It improved calcium retention significantly and strengthened the femur, showcasing enhanced mechanical properties of the bone.
Additionally, the complex aided in improving the structure of the bone’s trabecular network, making it thicker and more integral. We also noted an increase in beneficial gut bacteria associated with better calcium absorption and bone health after administering the complex.
Overall, the P + Ca + HMP complex demonstrated the potential to effectively deliver calcium, support a healthy gut environment, and promote stronger bones, making it a promising candidate for preventing calcium deficiency.
Our findings were impressive: chronic low calcium levels led to reduced calcium absorption and weakened bone architecture. However, the P + Ca + HMP complex turned the situation around. It improved calcium retention significantly and strengthened the femur, showcasing enhanced mechanical properties of the bone.
Additionally, the complex aided in improving the structure of the bone’s trabecular network, making it thicker and more integral. We also noted an increase in beneficial gut bacteria associated with better calcium absorption and bone health after administering the complex.
Overall, the P + Ca + HMP complex demonstrated the potential to effectively deliver calcium, support a healthy gut environment, and promote stronger bones, making it a promising candidate for preventing calcium deficiency.
8.8
Supports bone health
Most Useful Review
The quality is clean and tasty, with ingredients matching the picture. It's delicious, perfect with breakfast or yoghurt, and lasts about two months if not used daily. This helps prevent osteoporosis due to magnesium. It also enhances relaxation, aids sleep, improves skin and eye health, and strengthens immunity thanks to its antioxidants. It's a rich formula that complements a healthy diet.
Glucosamine Chondroitin Formulas
8
MSM enhances bone cell differentiation
Methylsulfonylmethane enhances BMP‑2‑induced osteoblast differentiation in mesenchymal stem cells.
Most Relevant Research
We investigated how methylsulfonylmethane (MSM) interacts with bone morphogenetic protein 2 (BMP-2) to potentially enhance the differentiation of mesenchymal stem cells (MSCs) into osteoblasts, which are crucial for bone health. The study revealed that both MSM and BMP-2, when combined, lead to increased levels of certain proteins that aid in this process.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
9.5
Slows osteoporosis progression
Most Useful Review
Doctor's Best Glucosamine, Chondroitin, and MSM is a remarkable tool for aiding cartilage health. It slows bone resorption and enhances calcium retention, promoting bone tissue repair and inhibiting cartilage degeneration. Its topical application can slow osteoporosis progression and stimulate regeneration in connective tissues. I highly recommend it for managing joint pain and enhancing the normal physiological processes!
MSM
8
MSM enhances bone cell differentiation
Methylsulfonylmethane enhances BMP‑2‑induced osteoblast differentiation in mesenchymal stem cells.
Most Relevant Research
We investigated how methylsulfonylmethane (MSM) interacts with bone morphogenetic protein 2 (BMP-2) to potentially enhance the differentiation of mesenchymal stem cells (MSCs) into osteoblasts, which are crucial for bone health. The study revealed that both MSM and BMP-2, when combined, lead to increased levels of certain proteins that aid in this process.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
9.5
Pain relief noted
Most Useful Review
Excellent! My mother is quite elderly and suffers from severe osteoporosis, as well as occasional low back pain following a lower back injury, which caused her to bend over. Due to concerns about side effects from Western medicine, alongside taking Life Extension’s Bone Strength Collagen Formula, I also added MSM for its anti-inflammatory benefits and to strengthen cartilage and connective tissue. After nearly a month, my mother can finally straighten her back and has experienced significant pain relief. This product has been beneficial for her back pain, and I plan to continue purchasing it.
Vitamin K
8
Vitamin K MK-4 aids diabetic osteoporosis
MK-4 Ameliorates Diabetic Osteoporosis in Angiogenesis-Dependent Bone Formation by Promoting Mitophagy in Endothelial Cells.
Most Relevant Research
We examined the potential of vitamin K menaquinone-4 (MK-4) to improve diabetic osteoporosis by focusing on its influence on bone formation and blood vessel health. Using a mouse model of type 2 diabetic osteoporosis, we assessed bone mass and the function of bone-forming cells. Our findings suggest that MK-4 can enhance blood vessel functionality, which is crucial for bone health, thus helping to alleviate diabetic osteoporosis symptoms. However, the exact long-term benefits require further research for clarity.
9.5
Reduces osteoporosis risk
Most Useful Review
Vitamin K2 (MK-7) is essential for treating osteoporosis by removing calcium from arteries and directing it to bones. I take it regularly with vitamin D3 to strengthen my bones. In high doses, it lowers cholesterol and prevents vascular calcification. The 100 mcg dosage is optimal, and the packaging is intact. It could be cheaper, though!
Calcium Magnesium
9.5
Vitamin D3 aids osteoporosis prevention
IgG4-RD-Associated Mikulicz Syndrome Without Classic Systemic Involvement-A Case Report.
Most Relevant Research
We looked into the effects of vitamin D3 on osteoporosis management, particularly in relation to glucocorticoid-induced complications. In a recent case involving an 85-year-old patient with IgG4-related disease, vitamin D3 was used alongside prednisone and azathioprine. The goal was to prevent bone density loss often seen with steroid treatments.
Our focus on this case revealed that vitamin D3 played an essential role in supporting the patient’s bone health. This addition helped mitigate some side effects of long-term steroid use, specifically protecting against osteoporosis, while the patient experienced significant improvements in their orbital symptoms.
Over the course of treatment, the patient showed remarkable recovery in just 24 hours, along with a complete resolution of issues related to their eye condition over the following year. While direct data on vitamin D3's standalone effectiveness isn't highlighted, its use in this context underscores a possible beneficial role in osteoporosis prevention when combined with corticosteroids.
Our focus on this case revealed that vitamin D3 played an essential role in supporting the patient’s bone health. This addition helped mitigate some side effects of long-term steroid use, specifically protecting against osteoporosis, while the patient experienced significant improvements in their orbital symptoms.
Over the course of treatment, the patient showed remarkable recovery in just 24 hours, along with a complete resolution of issues related to their eye condition over the following year. While direct data on vitamin D3's standalone effectiveness isn't highlighted, its use in this context underscores a possible beneficial role in osteoporosis prevention when combined with corticosteroids.
9.5
Reduced cravings
Most Useful Review
I take this as prescribed by my orthopaedic surgeon for osteoporosis management before and after pelvic surgery. It's a great remedy for the cramps common during pregnancy. After consuming other types of calcium without relief, I finally found this one. My calcium levels have improved, and the urge to eat chalk has disappeared entirely.
Calcium
4
Calcium's role in osteoporosis unclear
Optimizing bone health in people living with HIV: insights from a network meta-analysis of randomized controlled trials.
Most Relevant Research
We conducted a thorough review of various treatments for osteoporosis in people living with HIV, particularly focusing on the role of calcium. Our analysis included randomized controlled trials that compared different treatment strategies, such as calcium combined with medications like zoledronate or alendronate.
While zoledronate showed promising results in improving bone mineral density, calcium was often used alongside these treatments. Unfortunately, this combination makes it difficult to isolate the specific effects of calcium on osteoporosis. We found that alendronate, although it helped reduce certain bone turnover markers, did not significantly improve bone density.
Overall, the study indicates that while calcium plays a role in treatment combinations, its isolated impact on osteoporosis remains unclear. We emphasized the need for more focused research to determine calcium's true effectiveness in enhancing bone health for those affected by HIV.
While zoledronate showed promising results in improving bone mineral density, calcium was often used alongside these treatments. Unfortunately, this combination makes it difficult to isolate the specific effects of calcium on osteoporosis. We found that alendronate, although it helped reduce certain bone turnover markers, did not significantly improve bone density.
Overall, the study indicates that while calcium plays a role in treatment combinations, its isolated impact on osteoporosis remains unclear. We emphasized the need for more focused research to determine calcium's true effectiveness in enhancing bone health for those affected by HIV.
9.5
Supports osteoporosis treatment
Most Useful Review
Calcium is vital for human health. A deficiency can lead to osteoporosis. Magnesium calms the nervous system, while zinc strengthens immunity. This 3-in-1 combo, featuring D3 to enhance calcium absorption, is an excellent supplement for its price and quality.
Lactoferrin
8
Lactoferrin shows promise for osteoporosis
The role of lactoferrin in bone remodeling: evaluation of its potential in targeted delivery and treatment of metabolic bone diseases and orthopedic conditions.
Most Relevant Research
We explored how lactoferrin (Lf) could impact osteoporosis, a condition characterized by weakened bones. The research highlights Lf's significant role in bone remodeling by influencing the activity of various cells involved in bone health, like osteoblasts, osteoclasts, and chondrocytes.
Our findings indicate that Lf can stimulate bone formation while reducing bone resorption. This is crucial for reversing the effects of osteoporosis, where bone loss is prevalent. We observed that Lf enhances the function and growth of osteoblasts—cells responsible for building bone—while inhibiting the activity of osteoclasts, which break down bone.
Additionally, studies have shown that Lf may help in repairing fractures more efficiently. However, because Lf is quite large, ensuring sufficient delivery to the bones can be a challenge. This suggests that while Lf has promising benefits, strategies to improve its bioavailability are necessary to maximize its effects in treating osteoporosis. Overall, Lf appears to be an exciting avenue for research in bone health, specifically for those struggling with osteoporosis.
Our findings indicate that Lf can stimulate bone formation while reducing bone resorption. This is crucial for reversing the effects of osteoporosis, where bone loss is prevalent. We observed that Lf enhances the function and growth of osteoblasts—cells responsible for building bone—while inhibiting the activity of osteoclasts, which break down bone.
Additionally, studies have shown that Lf may help in repairing fractures more efficiently. However, because Lf is quite large, ensuring sufficient delivery to the bones can be a challenge. This suggests that while Lf has promising benefits, strategies to improve its bioavailability are necessary to maximize its effects in treating osteoporosis. Overall, Lf appears to be an exciting avenue for research in bone health, specifically for those struggling with osteoporosis.
9.5
Antibacterial properties
Most Useful Review
Lactoferrin is a crucial protein found in breast milk that aids in iron absorption and possesses antibacterial properties. It combats pathogenic bacteria and is beneficial for fighting herpes viruses and preventing osteoporosis. I give my child one capsule daily, and I’ve found the Jarrow supplement to be the most effective in terms of price and quality. It’s proven to work, and I highly recommend it.
Calcium Plus Vitamin D
8
Vitamin D3 aids osteoporosis recovery
Determination of immune factor levels in serum and local hematoma samples of osteoporotic fracture patients and clinical study of the effect of active vitamin D3 treatment on immune factor levels.
Most Relevant Research
We explored how active vitamin D3 treatment could affect immune factors like interleukins and tumor necrosis factor in patients with osteoporotic fractures.
Our study involved two groups—one received conventional treatment with calcium, while the other received calcium plus active vitamin D3.
After seven days, we observed that vitamin D3 treatment appeared to boost fracture healing by influencing immune factor levels. This suggests a potential role for vitamin D3 in supporting recovery from osteoporotic fractures.
Our study involved two groups—one received conventional treatment with calcium, while the other received calcium plus active vitamin D3.
After seven days, we observed that vitamin D3 treatment appeared to boost fracture healing by influencing immune factor levels. This suggests a potential role for vitamin D3 in supporting recovery from osteoporotic fractures.
10
Essential for women
Most Useful Review
Calcium citrate with vitamin D3 is a true find. It absorbs completely and is vital for women to prevent osteoporosis while improving hair, nails, and teeth health.
Zinc
7
Dietary zinc linked to osteoporosis
Association between dietary zinc intake amount and prevalence of osteoporosis in middle-aged and elderly individuals: a cross-sectional study.
Most Relevant Research
We aimed to understand how dietary zinc intake relates to the prevalence of osteoporosis in middle-aged and elderly individuals. By analyzing data from over 7,300 participants aged 45 and older, we found that those diagnosed with osteoporosis had significantly lower zinc intake compared to those without the condition.
Our results, derived from comprehensive statistical analyses, indicate that higher dietary zinc levels are associated with lower odds of developing osteoporosis. Even when adjusting for various factors, the connection remained strong. This suggests that zinc may play an important role in bone health.
However, it’s essential to note that while lower levels of dietary zinc correlate with a higher prevalence of osteoporosis, the study did not directly address the impact of zinc treatment on improving osteoporosis outcomes. Therefore, while the data points to a relationship, we cannot conclusively say that increasing zinc intake will treat osteoporosis effectively.
Our results, derived from comprehensive statistical analyses, indicate that higher dietary zinc levels are associated with lower odds of developing osteoporosis. Even when adjusting for various factors, the connection remained strong. This suggests that zinc may play an important role in bone health.
However, it’s essential to note that while lower levels of dietary zinc correlate with a higher prevalence of osteoporosis, the study did not directly address the impact of zinc treatment on improving osteoporosis outcomes. Therefore, while the data points to a relationship, we cannot conclusively say that increasing zinc intake will treat osteoporosis effectively.
9.5
Supports osteoporosis treatment
Most Useful Review
A tiny capsule of zinc helps combat various health issues. This small dietary supplement is easy to consume and plays a crucial role in preventing diseases such as osteoporosis. Zinc contributes to skin cell renewal and collagen formation, reducing dryness and helping combat wrinkles and acne. The importance of zinc in overall health cannot be overstated, particularly in maintaining beauty and preventing various health problems.
Omega 3 Fish Oil
7
Oily fish benefits bone health
On the association between dietary oily fish intake and bone mineral density in frequent fish consumers of Amerindian ancestry. The three villages study.
Most Relevant Research
We investigated the relationship between oily fish consumption and bone mineral density in elderly individuals of Amerindian ancestry living in rural Ecuador.
The study involved 399 participants aged 60 and over, where we found that consuming at least 5.2 servings of oily fish per week was linked to a lower prevalence of osteopenia and osteoporosis, particularly in elderly women.
This suggests that dietary oily fish may support bone health in this specific population, highlighting the need for further studies in other groups to understand the overall impact better.
The study involved 399 participants aged 60 and over, where we found that consuming at least 5.2 servings of oily fish per week was linked to a lower prevalence of osteopenia and osteoporosis, particularly in elderly women.
This suggests that dietary oily fish may support bone health in this specific population, highlighting the need for further studies in other groups to understand the overall impact better.
8.8
Supports joint health
Most Useful Review
Omega-3s support joint health and help prevent osteoporosis. They reduce inflammation and fight bone loss, alleviating joint pain, and mitigate symptoms of rheumatoid arthritis while slowing cartilage degradation in arthrosis. The fish oil is of high quality with no side effects like heartburn. I take it regularly and find it excellent value for money.
Prebiotic Fiber Inulin
9
Inulin improves bone health markers
Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model.
Most Relevant Research
We investigated how inulin, a type of dietary fiber, impacts bone health in the context of osteoporosis, particularly in a model of postmenopausal women represented by ovarierectomized (OVX) rats. The study involved feeding these rats different diets that included various sources of calcium, both dairy and carbonate, sometimes accompanied by inulin or lactose.
Our findings revealed that inulin has a significant effect on the gut environment. Notably, it enhanced the production of beneficial short-chain fatty acids (SCFAs) and led to a lower intestinal pH. This change is coupled with an increase in certain beneficial gut bacteria, such as Allobaculum and Bifidobacterium, which play a role in gut health.
When we looked at bone health markers, we observed that inulin, in combination with calcium supplementation, was associated with higher bone mineral density and improved bone strength. Moreover, inulin seems to boost the expression of calcium absorption-related genes, which could potentially support better calcium uptake and retention.
Thus, while inulin alone showed promise in enhancing certain aspects of bone health, the beneficial effects were most pronounced when combined with adequate calcium sources. This insight emphasizes the importance of dietary choices in managing osteoporosis and promoting overall bone health.
Our findings revealed that inulin has a significant effect on the gut environment. Notably, it enhanced the production of beneficial short-chain fatty acids (SCFAs) and led to a lower intestinal pH. This change is coupled with an increase in certain beneficial gut bacteria, such as Allobaculum and Bifidobacterium, which play a role in gut health.
When we looked at bone health markers, we observed that inulin, in combination with calcium supplementation, was associated with higher bone mineral density and improved bone strength. Moreover, inulin seems to boost the expression of calcium absorption-related genes, which could potentially support better calcium uptake and retention.
Thus, while inulin alone showed promise in enhancing certain aspects of bone health, the beneficial effects were most pronounced when combined with adequate calcium sources. This insight emphasizes the importance of dietary choices in managing osteoporosis and promoting overall bone health.
8.8
Improves calcium absorption
Most Useful Review
In addition to its prebiotic effects, inulin significantly increases calcium absorption, reducing osteoporosis risk. It influences lipid metabolism, decreasing atherosclerosis risk and possibly preventing type II diabetes, with preliminary data suggesting anticarcinogenic effects. Inulin also combats functional constipation and nourishes beneficial gut bacteria to maintain microbiota balance.
Sports Fish Oil Omegas
8
Eicosapentaenoic acid's potential effects
Is there a role for essential fatty acids in osteoporosis?
Most Relevant Research
We explored the connection between eicosapentaenoic acid (EPA) and osteoporosis to understand how this essential fatty acid may influence bone health. Research suggests that osteoporosis, particularly in postmenopausal women and the elderly, might be linked to low-grade systemic inflammation.
Although glucocorticoids are strong anti-inflammatory agents, their use has been shown to induce osteoporosis instead of preventing it. This strange finding points to a more complex mechanism involving pro-inflammatory cytokines and hormones like estrogen.
It appears that eicosapentaenoic acid play a role as a mediator in this process. Supporting evidence shows that people with osteoporosis often have lower levels of unsaturated fatty acids, including EPA. Some studies imply that long-chain metabolites of EFAs, such as arachidonic acid and lipoxin A4, can benefit bone health.
However, the specifics of EPA's effectiveness in isolation from other essential fatty acids remain unclear, as it was not assessed separately in the studies reviewed. Nevertheless, the potential for EPA to contribute positively to osteoporosis management is a discussion worth continuing.
Although glucocorticoids are strong anti-inflammatory agents, their use has been shown to induce osteoporosis instead of preventing it. This strange finding points to a more complex mechanism involving pro-inflammatory cytokines and hormones like estrogen.
It appears that eicosapentaenoic acid play a role as a mediator in this process. Supporting evidence shows that people with osteoporosis often have lower levels of unsaturated fatty acids, including EPA. Some studies imply that long-chain metabolites of EFAs, such as arachidonic acid and lipoxin A4, can benefit bone health.
However, the specifics of EPA's effectiveness in isolation from other essential fatty acids remain unclear, as it was not assessed separately in the studies reviewed. Nevertheless, the potential for EPA to contribute positively to osteoporosis management is a discussion worth continuing.
9.5
Prevents osteoporosis
Most Useful Review
This Omega-3 fish oil, certified by IFOS, is extracted from wild Alaska pollock. Each capsule contains significant amounts of EPA and DHA. Its benefits include reducing cholesterol and triglycerides, managing blood pressure, preventing osteoporosis, and enhancing joint health. It’s recommended to take 1-2 capsules daily, and it’s a great value, currently on sale.
Coral Calcium
8
Vitamin D aids cancer treatment outcomes
A Systematic Review of Vitamin D Supplementation in Oncology: Chance of Science or Effectiveness?
Most Relevant Research
We explored the role of vitamin D (VD) supplementation in supporting cancer patients undergoing chemotherapy and radiotherapy, particularly regarding its effects on osteoporosis. The aim was to sift through scientific evidence to understand how vitamin D influences not just bone health but also alleviates the side effects of demanding cancer treatments.
Our findings indicated that adequate levels of VD are important for maintaining bone density in patients, especially those receiving preoperative chemoradiotherapy. Some studies showed that vitamin D supplementation could lessen certain severe side effects, like fatigue and nausea, often experienced during cancer treatments.
However, the evidence regarding the isolated effects of vitamin D on osteoporosis, specifically, was limited due to the varied designs of the included studies. Despite these challenges, it seems clear that vitamin D plays a valuable role in managing bone health and reducing treatment-related complications.
Our findings indicated that adequate levels of VD are important for maintaining bone density in patients, especially those receiving preoperative chemoradiotherapy. Some studies showed that vitamin D supplementation could lessen certain severe side effects, like fatigue and nausea, often experienced during cancer treatments.
However, the evidence regarding the isolated effects of vitamin D on osteoporosis, specifically, was limited due to the varied designs of the included studies. Despite these challenges, it seems clear that vitamin D plays a valuable role in managing bone health and reducing treatment-related complications.
9.5
Helped recovery
Most Useful Review
Recommended due to my mother-in-law's hip fracture. Since using this coral calcium, her osteoporosis improved significantly alongside her recovery. I also benefit from it for allergies and eczema.
Calcium Citrate
8
Vitamin D aids cancer treatment outcomes
A Systematic Review of Vitamin D Supplementation in Oncology: Chance of Science or Effectiveness?
Most Relevant Research
We explored the role of vitamin D (VD) supplementation in supporting cancer patients undergoing chemotherapy and radiotherapy, particularly regarding its effects on osteoporosis. The aim was to sift through scientific evidence to understand how vitamin D influences not just bone health but also alleviates the side effects of demanding cancer treatments.
Our findings indicated that adequate levels of VD are important for maintaining bone density in patients, especially those receiving preoperative chemoradiotherapy. Some studies showed that vitamin D supplementation could lessen certain severe side effects, like fatigue and nausea, often experienced during cancer treatments.
However, the evidence regarding the isolated effects of vitamin D on osteoporosis, specifically, was limited due to the varied designs of the included studies. Despite these challenges, it seems clear that vitamin D plays a valuable role in managing bone health and reducing treatment-related complications.
Our findings indicated that adequate levels of VD are important for maintaining bone density in patients, especially those receiving preoperative chemoradiotherapy. Some studies showed that vitamin D supplementation could lessen certain severe side effects, like fatigue and nausea, often experienced during cancer treatments.
However, the evidence regarding the isolated effects of vitamin D on osteoporosis, specifically, was limited due to the varied designs of the included studies. Despite these challenges, it seems clear that vitamin D plays a valuable role in managing bone health and reducing treatment-related complications.
9.5
Effective for healing bones
Most Useful Review
At 58, after breaking an arm and leg, I began taking calcium citrate with vitamin D3. When my plaster was removed after 1.5 months, my bones had fused well, so I continued using it until the pack was complete. I've since ordered more and take it in intervals of 2 months for osteoporosis prevention. I am very pleased with its effectiveness for strengthening bones.
B12
4
Taurine outperforms vitamin B12
Integrative in-silico and in-vitro analysis of taurine and vitamin B12 in modulating PPARγ and Wnt signaling in hyperhomocysteinemia-induced osteoporosis.
Most Relevant Research
We investigated how vitamin B12 influences osteoporosis, especially in cases linked to high homocysteine levels, alongside taurine. Through molecular docking techniques and laboratory experiments, we discovered that taurine and homocysteine interact with PPARγ, a crucial protein in bone health.
Vitamin B12 showed some positive effects on bone health; however, it didn't perform as strongly as taurine. We noticed that while vitamin B12 contributes beneficially, it can't fully counteract the damaging impact of hyperhomocysteinemia on bone. The study highlighted that taurine, particularly when combined with vitamin B12, exhibited greater effectiveness against osteoporosis.
In conclusion, while vitamin B12 has its merits in promoting bone health, taurine appears to play a more significant role. This suggests that further exploration into taurine's mechanisms could be valuable for developing treatments for osteoporosis.
Vitamin B12 showed some positive effects on bone health; however, it didn't perform as strongly as taurine. We noticed that while vitamin B12 contributes beneficially, it can't fully counteract the damaging impact of hyperhomocysteinemia on bone. The study highlighted that taurine, particularly when combined with vitamin B12, exhibited greater effectiveness against osteoporosis.
In conclusion, while vitamin B12 has its merits in promoting bone health, taurine appears to play a more significant role. This suggests that further exploration into taurine's mechanisms could be valuable for developing treatments for osteoporosis.
9.5
Supports general health
Most Useful Review
This product is extremely useful. It greatly benefits the body, nerves, and overall health. I use it alongside my family as it’s one of the most important vitamins for daily health. It promotes bone growth and helps prevent osteoporosis. Nutritionists emphasise the significance of vitamin B12 and its role in supporting mood and mental health.