We observed that omega-3 fatty acids, particularly EPA and DHA, could be beneficial for patients struggling with acne. Over 16 weeks, 60 participants followed a Mediterranean diet and received algae-derived omega-3 supplements.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
Read More
9
Docosahexaenoic acid reduces acne risk
The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study.
We investigated the relationship between docosahexaenoic acid (DHA), a type of polyunsaturated fatty acid (PUFA), and the occurrence of acne. Using a method called Mendelian randomization, we looked at how genetic variations associated with DHA might influence acne development in large groups of participants, including over 115,000 individuals from the UK and nearly 364,000 of Finnish ancestry.
Our findings revealed that higher levels of DHA are actually linked to a lower risk of developing acne. Specifically, we found that a significant increase in DHA levels or its proportion compared to total fatty acids corresponded with a reduced likelihood of acne. In contrast, higher levels of linoleic acid (LA), another type of PUFA, were associated with an increased acne risk.
This suggests that balancing our intake of these fatty acids might be important for skin health. Notably, the results pointed towards a genetic connection involving the FADS1 gene, which appears to play a role in how these fatty acids affect our skin.
In conclusion, increasing DHA could be beneficial in protecting against acne, while excessive linoleic acid might have the opposite effect. Overall, our study highlights the importance of these fatty acids in understanding acne risk better.
Read More
8
Impact of fatty acids on acne
Exploring clinical and genetic evidence in association between unsaturated fatty acids and acne.
We systematically reviewed studies on how omega-3 and omega-6 fatty acids affect acne. Our findings indicate that omega-3s may help reduce acne, while some omega-6s could exacerbate it.
Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.
More diverse research is needed to fully understand these effects across different groups.
Read More
Most Useful Reviews
7.5
Acne improvement
2 people found this helpful
Very satisfied :) After using these pills, I experienced a problem with acne on my face, and I am very pleased with the outcome. I didn't expect such a result; it feels like these pills are providing the body with vitamins and fats that I lack in my diet. I haven't noticed any side effects, which is a relief. Overall, it's a fantastic product, and I highly recommend it!
Read More
9
Acne reduction
1 people found this helpful
Great! I love this omega and have been taking it for several years. I used to have acne on my chin, but after taking omega for a longer period, it disappeared.
Read More
9
Acne symptoms improvement
I have purchased this product multiple times. It helps reduce inflammation, regulate endocrine levels, and improve acne symptoms. My daughter now has significantly less acne after using it, and I will continue to buy it.
We observed that omega-3 fatty acids, particularly EPA and DHA, could be beneficial for patients struggling with acne. Over 16 weeks, 60 participants followed a Mediterranean diet and received algae-derived omega-3 supplements.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
Read More
9
Docosahexaenoic acid reduces acne risk
The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study.
We investigated the relationship between docosahexaenoic acid (DHA), a type of polyunsaturated fatty acid (PUFA), and the occurrence of acne. Using a method called Mendelian randomization, we looked at how genetic variations associated with DHA might influence acne development in large groups of participants, including over 115,000 individuals from the UK and nearly 364,000 of Finnish ancestry.
Our findings revealed that higher levels of DHA are actually linked to a lower risk of developing acne. Specifically, we found that a significant increase in DHA levels or its proportion compared to total fatty acids corresponded with a reduced likelihood of acne. In contrast, higher levels of linoleic acid (LA), another type of PUFA, were associated with an increased acne risk.
This suggests that balancing our intake of these fatty acids might be important for skin health. Notably, the results pointed towards a genetic connection involving the FADS1 gene, which appears to play a role in how these fatty acids affect our skin.
In conclusion, increasing DHA could be beneficial in protecting against acne, while excessive linoleic acid might have the opposite effect. Overall, our study highlights the importance of these fatty acids in understanding acne risk better.
Read More
8
Impact of fatty acids on acne
Exploring clinical and genetic evidence in association between unsaturated fatty acids and acne.
We systematically reviewed studies on how omega-3 and omega-6 fatty acids affect acne. Our findings indicate that omega-3s may help reduce acne, while some omega-6s could exacerbate it.
Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.
More diverse research is needed to fully understand these effects across different groups.
Read More
8
Omega-3 effects on acne studied
The adjuvant treatment role of ω-3 fatty acids by regulating gut microbiota positively in the acne vulgaris.
We investigated whether omega-3 fatty acids could help manage acne by influencing gut bacteria. Over 12 weeks, untreated acne patients were divided into two groups: one received omega-3 supplements while the other didn’t. We also tested in rats with an acne model. The findings indicated that omega-3 increased gut bacteria diversity and enhanced beneficial bacteria linked to anti-inflammatory effects. However, despite these promising changes, we did not observe a significant overall impact on acne improvement in patients.
Read More
8
Omega-3 improves acne symptoms
Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial.
We examined how omega-3 fatty acids and gamma-linolenic acid could help with acne in a well-structured 10-week study. Involving 45 participants with mild to moderate acne, we compared those taking omega-3, those taking gamma-linolenic acid, and a control group.
The findings were promising: both omega-3 and gamma-linolenic acid showed a significant reduction in both inflammatory and non-inflammatory acne lesions. Participants also reported noticeable improvements in their skin. Importantly, no severe side effects were noted, indicating these supplements might be a beneficial addition to existing acne treatments.
Very satisfied :) After using these pills, I experienced a problem with acne on my face, and I am very pleased with the outcome. I didn't expect such a result; it feels like these pills are providing the body with vitamins and fats that I lack in my diet. I haven't noticed any side effects, which is a relief. Overall, it's a fantastic product, and I highly recommend it!
Read More
9
Acne reduction
1 people found this helpful
Great! I love this omega and have been taking it for several years. I used to have acne on my chin, but after taking omega for a longer period, it disappeared.
Read More
9
Acne symptoms improvement
I have purchased this product multiple times. It helps reduce inflammation, regulate endocrine levels, and improve acne symptoms. My daughter now has significantly less acne after using it, and I will continue to buy it.
Read More
9
Teen acne disappearance
This omega is the best I've ever taken. My daughter's acne on her face has vanished. I have consistently chosen this manufacturer and remain very satisfied.
Read More
9
Improved skin tone
I am delighted that I started taking Omega. During pregnancy, I had normal tests with a complex vitamin regimen. After giving birth, my health deteriorated, as my body lacked essential elements while nursing. Now, I have significantly improved my condition by taking the necessary supplements, and my face shows no signs of acne. I believe Omega-3 has played a crucial role in this revival.
Acne is a common skin condition that affects people of all ages, though it's especially prevalent among teenagers and young adults. It occurs when hair follicles become clogged with oil and dead skin cells, leading to the formation of pimples, blackheads, and cysts. The main factors contributing to acne include excess oil production, hormonal changes, and the presence of bacteria on the skin. Acne can manifest in various forms, from mild cases with just a few breakouts to more severe forms that can cause significant inflammation and scarring.
Treatment for acne varies depending on its severity and can range from over-the-counter topical treatments like benzoyl peroxide and salicylic acid to prescription medications including retinoids and antibiotics. Lifestyle adjustments, such as maintaining a balanced diet and proper skin hygiene, may also contribute to managing and reducing breakouts. Despite being a common skin issue, the psychological impact of acne should not be underestimated, as it can affect self-esteem and overall quality of life.
Omega-3 fish oil is a nutritional supplement derived from the fatty tissues of fish, particularly fatty fish like salmon, mackerel, and sardines. It is rich in omega-3 fatty acids, which are essential fats that the body cannot produce on its own. The most significant types of omega-3s found in fish oil are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both of which are known for their numerous health benefits. These include reducing inflammation, supporting heart health, and promoting brain function.
Incorporating omega-3 fish oil into your diet can be beneficial if you don’t consume enough fish regularly. Many health experts recommend oily fish as a part of a balanced diet due to their high omega-3 content. For those who find it difficult to include fish in their meals, fish oil supplements can offer a convenient alternative, providing the same essential fatty acids in concentrated form. However, it’s essential to choose high-quality supplements that are third-party tested for purity and potency to avoid contaminants such as heavy metals or other toxins that can impact health.
Research on the effects of Omega-3 fish oil on acne suggests that it may offer some benefits, particularly due to its anti-inflammatory properties. Omega-3 fatty acids, which are found in fish oil, are known to help reduce inflammation in the body, and since acne is often associated with inflammatory processes, some individuals may experience a decrease in the severity or frequency of their breakouts. Additionally, Omega-3s can help improve skin hydration and may support overall skin health, which can be beneficial for those dealing with acne-prone skin.
However, while some studies have shown promising results, the evidence is not definitive enough to make Omega-3 fish oil a guaranteed solution for acne. It is also worth noting that dietary changes and supplements should complement a comprehensive skincare regimen tailored to individual skin types and needs. If you're considering adding Omega-3 supplements to your routine for acne management, it's a good idea to consult with a healthcare professional to ensure it aligns with your overall health goals and skincare plan.
Based on user reviews, it seems that the time to see noticeable results from taking this supplement for acne can vary. Many users report improvements within a few weeks of consistent use. For example, one user mentioned positive changes after only three weeks of taking Omega-3, highlighting improvements in skin texture and reduction in small pimples Read Review. Others have mentioned that longer-term use has been necessary, with several users noting significant reductions in acne after months of supplementation Read Review.
Users have expressed satisfaction with the supplement's effect on their skin, suggesting that it may contribute positively to managing acne, particularly for mothers or individuals experiencing hormonal changes Read Review. Overall, while individual experiences may vary, many users seem to see beneficial effects within the first few weeks to months of starting the supplement.
The research on omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), suggests a promising connection to acne management. Several studies demonstrate that increasing omega-3 levels can significantly improve the severity of acne. For instance, in a study involving participants who supplemented with algae-derived omega-3s while following a Mediterranean diet, notable improvements in both inflammatory and non-inflammatory acne lesions were observed after 16 weeks. This underscores the potential of incorporating omega-3 fatty acids as a complementary approach to traditional acne treatments [2], [7].
Additionally, the findings indicate that omega-3s may help reduce the side effects experienced by patients undergoing conventional treatments, such as isotretinoin [4]. However, the results also highlight that while omega-3s can benefit some individuals, the effects can vary among patients, and they are best viewed as a supportive option rather than a standalone solution for acne [5]. With further diverse research needed, omega-3 supplementation appears to be a viable choice for those seeking to enhance their acne treatment strategy [1].
Users report a range of improvements in their acne symptoms after taking Omega-3 supplements, often citing significant changes within weeks to months. For instance, one user noted that after consistent use, their daughter's acne considerably diminished, leading to a high level of satisfaction with the product Read Review. Another user described their acne issues around the chin completely disappearing after long-term use, reinforcing the notion that patience can yield favorable results Read Review.
Moreover, users have shared that the supplement not only helps with acne but also improves overall skin health. For example, one review highlights the relief from skin issues post-pregnancy and the pivotal role of Omega-3 in enhancing skin condition, as well as eliminating acne Read Review, while another user mentions complete clearance of back acne after starting the supplement Read Review. Although experiences can vary widely from person to person, these anecdotal accounts suggest that Omega-3 may be beneficial for managing acne and promoting healthier skin.
Based on user reviews, many individuals report positive experiences when combining Omega-3 supplements with other products or routines for treating acne. For instance, users noted that after starting Omega-3, they experienced significant reductions in acne symptoms without adverse side effects. One reviewer specifically mentioned that their daughter saw a marked decrease in facial acne related to hormonal fluctuations during her menstrual cycle after integrating the supplement into her regimen Read Review. Furthermore, consistent long-term usage was praised; another user stated their chin acne disappeared after several months of taking Omega-3 Read Review.
Additionally, some users highlighted that Omega-3 not only addressed acne but also improved overall skin health, suggesting a holistic benefit. For example, one reviewer mentioned that their skin showed no signs of acne after giving birth while incorporating Omega-3 along with a complex vitamin regimen Read Review. Another user linked Omega's benefits to their ability to manage skin challenges caused by poor environmental conditions, further emphasizing its role in enhancing skincare routines Read Review. Overall, these reviews point to Omega-3 as a valuable addition to acne management, especially when combined with other health-conscious practices.
Research indicates that omega-3 fatty acids, specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), can be beneficial for individuals dealing with acne. In a study involving 60 participants over 16 weeks on a Mediterranean diet with algae-derived omega-3 supplementation, significant improvements in acne severity were observed when optimal omega-3 levels were achieved [2]. Another trial assessed the effects of fish oil in 13 individuals taking 3 grams daily over 12 weeks, showing varied individual responses, where some participants with moderate to severe acne saw improvements [8].
Overall, the data suggests aiming for a dosage of around 2,000 mg to 3,000 mg of combined EPA and DHA per day as part of an integrated acne treatment strategy [7]. Although individual responses can vary, enhancing omega-3 intake might be a useful addition to acne management plans, particularly for those suffering from inflammatory acne lesions or alongside conventional treatments [5]. While omega-3s may not serve as a standalone cure for acne, their anti-inflammatory properties could help alleviate some symptoms and assist in improving overall skin health [6].
7.5
Acne-free periods
I bought Omega-3 from this brand for the first time on a recommendation and we have been using it as a family for three weeks. My husband hasn't noticed changes yet, but my daughter and I have. My heels, which had cracks, are now soft, and the skin on my elbows no longer peels. Notably, I did not have acne on my face before my menstrual cycle, and my daughter’s small pimples in the décolleté area have also cleared up.
9
Acne reduction
1 people found this helpful
Great! I love this omega and have been taking it for several years. I used to have acne on my chin, but after taking omega for a longer period, it disappeared.
9
Improved skin tone
I am delighted that I started taking Omega. During pregnancy, I had normal tests with a complex vitamin regimen. After giving birth, my health deteriorated, as my body lacked essential elements while nursing. Now, I have significantly improved my condition by taking the necessary supplements, and my face shows no signs of acne. I believe Omega-3 has played a crucial role in this revival.
9
Acne symptoms improvement
I have purchased this product multiple times. It helps reduce inflammation, regulate endocrine levels, and improve acne symptoms. My daughter now has significantly less acne after using it, and I will continue to buy it.
9
Banishment of back acne
This is the best Omega-3! The quality is excellent, and the compact packaging makes it easy to carry. I had acne on my back for many years; however, after I started taking omega, it all disappeared!
7.5
Skin hydration
Our city has poor water quality and harsh winters, making skin hydration challenging without omega. This omega works best for me as it is cleaner compared to others and reasonably priced. When I stop taking it, my skin and heels suffer again, and I've noticed a reduction in acne as well. Overall, it works effectively for my skin!
9
Omega-3 improves acne severity
Exploring the potential of omega-3 fatty acids in acne patients: A prospective intervention study.
We observed that omega-3 fatty acids, particularly EPA and DHA, could be beneficial for patients struggling with acne. Over 16 weeks, 60 participants followed a Mediterranean diet and received algae-derived omega-3 supplements.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
8
Omega-3 improves acne symptoms
Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial.
We examined how omega-3 fatty acids and gamma-linolenic acid could help with acne in a well-structured 10-week study. Involving 45 participants with mild to moderate acne, we compared those taking omega-3, those taking gamma-linolenic acid, and a control group.
The findings were promising: both omega-3 and gamma-linolenic acid showed a significant reduction in both inflammatory and non-inflammatory acne lesions. Participants also reported noticeable improvements in their skin. Importantly, no severe side effects were noted, indicating these supplements might be a beneficial addition to existing acne treatments.
7
Omega-3 reduces isotretinoin side effects
Effectiveness Of Oral Omega 3 In Reducing Mucocutaneous Side Effects Of Oral Isotretinoin In Patients With Acne Vulgaris.
We set out to investigate whether omega-3 fish oil could reduce the common side effects associated with isotretinoin treatment in patients with acne vulgaris. In our randomized control trial involving 60 participants, we found that those taking omega-3 experienced significantly fewer issues like dry lips compared to those on a placebo.
Our findings suggest that omega-3 may offer a helpful solution for managing these mucocutaneous side effects, improving comfort during acne treatment. Overall, this research indicates that adding omega-3 could be beneficial for those taking isotretinoin.
7
Omega-3s benefit inflammatory skin conditions
The Potential Uses of Omega-3 Fatty Acids in Dermatology: A Review.
We examined a variety of studies on omega-3 fatty acids (O3FAs) and their impact on skin conditions, including acne. The review encompassed 38 studies, highlighting benefits such as a reduction in inflammatory lesions and side effects from other acne treatments like isotretinoin.
Although the findings suggest potential advantages, specifically for inflammatory skin issues, O3FAs are best viewed as a supplemental option rather than a standalone solution for acne. Overall, their low cost and safety make them a viable addition to treatment strategies for those seeking to improve their skin health.
8
Impact of fatty acids on acne
Exploring clinical and genetic evidence in association between unsaturated fatty acids and acne.
We systematically reviewed studies on how omega-3 and omega-6 fatty acids affect acne. Our findings indicate that omega-3s may help reduce acne, while some omega-6s could exacerbate it.
Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.
More diverse research is needed to fully understand these effects across different groups.
4
Fish oil may improve acne severity
Effects of fish oil supplementation on inflammatory acne.
We evaluated the effects of omega-3 fish oil on inflammatory acne in a group of 13 individuals over 12 weeks. Each participant continued their regular acne treatments while taking three grams of fish oil daily.
While the overall results showed no significant changes in acne severity scores or inflammatory lesion counts, we observed varied individual responses. Eight participants showed improvement, particularly those with moderate to severe acne, while four experienced worsening conditions.
These findings suggest that omega-3 supplementation may be beneficial for some, but further research is necessary to confirm its effectiveness.
4
Omega-3 acids' role in acne
Decreased eicosapentaenoic acid levels in acne vulgaris reveals the presence of a proinflammatory state.
This study focused on the relationship between omega-3 fatty acids and acne. We examined the serum levels of various fatty acids in 31 patients with acne compared to 21 healthy individuals.
Our findings showed that levels of eicosapentaenoic acid (EPA) were significantly lower in acne sufferers. Higher ratios of arachidonic acid to EPA indicated a proinflammatory state in those with acne.
While omega-3s might offer some benefits due to their anti-inflammatory potential, the study suggests that they alone may not be a standalone cure for acne.
References
Zhang L, Li Y, Pu Y, Dang T, Shi Q, et al. Exploring clinical and genetic evidence in association between unsaturated fatty acids and acne. Eur J Nutr. 2025;64:130. doi:10.1007/s00394-025-03647-4
Guertler A, Neu K, Lill D, Clanner-Engelshofen B, French LE, et al. Exploring the potential of omega-3 fatty acids in acne patients: A prospective intervention study. J Cosmet Dermatol. 2024;23:3295. doi:10.1111/jocd.16434
Huang Y, Liu F, Lai J, Jiang S, Tan X, et al. The adjuvant treatment role of ω-3 fatty acids by regulating gut microbiota positively in the acne vulgaris. J Dermatolog Treat. 2024;35:2299107. doi:10.1080/09546634.2023.2299107
Zainab Z, Malik NA, Obaid S, Malik S, Aftab K, et al. Effectiveness Of Oral Omega 3 In Reducing Mucocutaneous Side Effects Of Oral Isotretinoin In Patients With Acne Vulgaris. J Ayub Med Coll Abbottabad. 2021;33:60.
Thomsen BJ, Chow EY, Sapijaszko MJ. The Potential Uses of Omega-3 Fatty Acids in Dermatology: A Review. J Cutan Med Surg. 2020;24:481. doi:10.1177/1203475420929925
Aslan İ, Özcan F, Karaarslan T, Kıraç E, Aslan M. Decreased eicosapentaenoic acid levels in acne vulgaris reveals the presence of a proinflammatory state. Prostaglandins Other Lipid Mediat. 2017;128-129:1. doi:10.1016/j.prostaglandins.2016.12.001
Jung JY, Kwon HH, Hong JS, Yoon JY, Park MS, et al. Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial. Acta Derm Venereol. 2014;94:521. doi:10.2340/00015555-1802
Khayef G, Young J, Burns-Whitmore B, Spalding T. Effects of fish oil supplementation on inflammatory acne. Lipids Health Dis. 2012;11:165. doi:10.1186/1476-511X-11-165
Desbois AP, Lawlor KC. Antibacterial activity of long-chain polyunsaturated fatty acids against Propionibacterium acnes and Staphylococcus aureus. Mar Drugs. 2013;11:4544. doi:10.3390/md11114544
Rubin MG, Kim K, Logan AC. Acne vulgaris, mental health and omega-3 fatty acids: a report of cases. Lipids Health Dis. 2008;7:36. doi:10.1186/1476-511X-7-36
Kim BR, Kim G, Jin SP, Choi CW, Kim J, et al. The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study. Br J Dermatol. 2025. doi:10.1093/bjd/ljaf052