' 
SCIENTIFIC SCORE
Possibly Effective
Based on 28 Researches
7.9
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: One (1) Capsule
Amount Per Serving
%DV
Calories
0
Total Carbohydrate
0 g
0%+
Total Sugars
0 g
**
Incl. 0 g Added Sugars
0%+
Lactobacillus rhamnosus GG
83 mg (20 billion CFUs)
**
Inulin (Chicory root extract)
200 mg
**
Top Medical Research Studies
9
Lactobacillus rhamnosus DNA affects allergies
Probiotic DNA regulates intestinal Th2 polarization by inducing epithelial cells to produce PD-L1.
High relevance for allergy research
We explored how Lactobacillus rhamnosus DNA might affect allergic responses linked to Th2 polarization. Using a specific protocol in mice, we administered LR-DNA daily for five days and observed its impact on intestinal cells. The results showed that LR-DNA increased PD-L1 expression in these cells, which then helped trigger the death of Th2 cells.
Importantly, while we found promising effects, the study suggests that just the DNA from the probiotic—not the live bacteria—was effective in reducing allergic responses.
Importantly, while we found promising effects, the study suggests that just the DNA from the probiotic—not the live bacteria—was effective in reducing allergic responses.
Read More
9
Lr improves lung inflammation management
Lactobacillus rhamnosus Modulates Lung Inflammation and Mitigates Gut Dysbiosis in a Murine Model of Asthma-COPD Overlap Syndrome.
High relevance for ACOS treatment
We sought to understand how Lactobacillus rhamnosus (Lr) influences lung inflammation and gut health in asthma-COPD overlap syndrome (ACOS). In an experimental study with mice, we introduced Lr treatment after inducing ACOS.
Our findings indicated that Lr treatment reduced lung inflammation, bronchial hyperreactivity, and improved gut microbiota diversity. Specifically, Lr lowered the levels of pro-inflammatory cytokines and restored beneficial immune markers. This study reveals that Lr could play a role in managing symptoms of ACOS by modulating both lung inflammation and gut dysbiosis.
Our findings indicated that Lr treatment reduced lung inflammation, bronchial hyperreactivity, and improved gut microbiota diversity. Specifically, Lr lowered the levels of pro-inflammatory cytokines and restored beneficial immune markers. This study reveals that Lr could play a role in managing symptoms of ACOS by modulating both lung inflammation and gut dysbiosis.
Read More
9
Lactobacillus rhamnosus mitigates airway inflammation
Lactobacillus rhamnosus 76 alleviates airway inflammation in ovalbumin-allergic mice and improves mucus secretion by down-regulating STAT6/SPDEF pathway.
Demonstrates probiotic effect on allergies
We explored the effect of Lactobacillus rhamnosus 76 (LR76) on mice suffering from allergies triggered by ovalbumin.
In our study, LR76 helped reduce signs of airway inflammation and improved mucus secretion by affecting certain pathways involved in immune response.
Mice that received LR76 showed a decrease in multiple inflammatory markers, indicating a potential benefit of this probiotic on allergy-related symptoms. However, while promising, we must note that this study was conducted in animals, and results may differ in humans.
In our study, LR76 helped reduce signs of airway inflammation and improved mucus secretion by affecting certain pathways involved in immune response.
Mice that received LR76 showed a decrease in multiple inflammatory markers, indicating a potential benefit of this probiotic on allergy-related symptoms. However, while promising, we must note that this study was conducted in animals, and results may differ in humans.
Read More
Most Useful Reviews
8.8
Milk allergy relief
Very good probiotic for patients with milk allergies, as advised by my doctor.
Read More
8.8
Skin allergy aid
This has been quite helpful for my skin allergies; it’s excellent stuff.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 28 Researches
7.9
9
Lactobacillus rhamnosus DNA affects allergies
Probiotic DNA regulates intestinal Th2 polarization by inducing epithelial cells to produce PD-L1.
High relevance for allergy research
We explored how Lactobacillus rhamnosus DNA might affect allergic responses linked to Th2 polarization. Using a specific protocol in mice, we administered LR-DNA daily for five days and observed its impact on intestinal cells. The results showed that LR-DNA increased PD-L1 expression in these cells, which then helped trigger the death of Th2 cells.
Importantly, while we found promising effects, the study suggests that just the DNA from the probiotic—not the live bacteria—was effective in reducing allergic responses.
Importantly, while we found promising effects, the study suggests that just the DNA from the probiotic—not the live bacteria—was effective in reducing allergic responses.
Read More
9
Probiotics enhance food allergy treatment
Probiotics and other adjuvants in allergen-specific immunotherapy for food allergy: a comprehensive review.
Highly relevant to allergy treatment
We examined how probiotics, especially Lactobacillus rhamnosus, can improve treatments for food allergies through allergen-specific immunotherapy (FA-AIT). These helpful bacteria promote better immune responses, leading to increased tolerance. Clinical trials revealed that combining Lactobacillus rhamnosus with peanut immunotherapy led to better desensitization rates and positive immune changes.
While FA-AIT remains under study, integrating probiotics into these treatments appears promising for achieving lasting relief from allergies and improving patient well-being.
While FA-AIT remains under study, integrating probiotics into these treatments appears promising for achieving lasting relief from allergies and improving patient well-being.
Read More
9
Lr improves lung inflammation management
Lactobacillus rhamnosus Modulates Lung Inflammation and Mitigates Gut Dysbiosis in a Murine Model of Asthma-COPD Overlap Syndrome.
High relevance for ACOS treatment
We sought to understand how Lactobacillus rhamnosus (Lr) influences lung inflammation and gut health in asthma-COPD overlap syndrome (ACOS). In an experimental study with mice, we introduced Lr treatment after inducing ACOS.
Our findings indicated that Lr treatment reduced lung inflammation, bronchial hyperreactivity, and improved gut microbiota diversity. Specifically, Lr lowered the levels of pro-inflammatory cytokines and restored beneficial immune markers. This study reveals that Lr could play a role in managing symptoms of ACOS by modulating both lung inflammation and gut dysbiosis.
Our findings indicated that Lr treatment reduced lung inflammation, bronchial hyperreactivity, and improved gut microbiota diversity. Specifically, Lr lowered the levels of pro-inflammatory cytokines and restored beneficial immune markers. This study reveals that Lr could play a role in managing symptoms of ACOS by modulating both lung inflammation and gut dysbiosis.
Read More
9
Lactobacillus rhamnosus mitigates airway inflammation
Lactobacillus rhamnosus 76 alleviates airway inflammation in ovalbumin-allergic mice and improves mucus secretion by down-regulating STAT6/SPDEF pathway.
Demonstrates probiotic effect on allergies
We explored the effect of Lactobacillus rhamnosus 76 (LR76) on mice suffering from allergies triggered by ovalbumin.
In our study, LR76 helped reduce signs of airway inflammation and improved mucus secretion by affecting certain pathways involved in immune response.
Mice that received LR76 showed a decrease in multiple inflammatory markers, indicating a potential benefit of this probiotic on allergy-related symptoms. However, while promising, we must note that this study was conducted in animals, and results may differ in humans.
In our study, LR76 helped reduce signs of airway inflammation and improved mucus secretion by affecting certain pathways involved in immune response.
Mice that received LR76 showed a decrease in multiple inflammatory markers, indicating a potential benefit of this probiotic on allergy-related symptoms. However, while promising, we must note that this study was conducted in animals, and results may differ in humans.
Read More
9
Probiotic reduces allergy symptoms
[The results of the use of a combined probiotic ( and spp. ВB-12) in children with gastrointestinal and skin manifestations of food allergy].
Moderately relevant for allergy treatment
We assessed the impact of a combined probiotic, including Lactobacillus rhamnosus, on children with food allergies. In a study involving 92 children aged 4 to 5 years, half received the probiotic for 21 days while the control group did not.
Results showed a significant reduction in skin and gastrointestinal symptoms in those using the probiotic, alongside decreased levels of the allergy marker IgE. Although some symptoms returned over time, the overall severity remained lower than at the start.
Our findings suggest that this probiotic could improve allergy symptoms, supporting its potential as a treatment option for children.
Results showed a significant reduction in skin and gastrointestinal symptoms in those using the probiotic, alongside decreased levels of the allergy marker IgE. Although some symptoms returned over time, the overall severity remained lower than at the start.
Our findings suggest that this probiotic could improve allergy symptoms, supporting its potential as a treatment option for children.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
8.8
Milk allergy relief
Very good probiotic for patients with milk allergies, as advised by my doctor.
8.8
Skin allergy aid
This has been quite helpful for my skin allergies; it’s excellent stuff.
