'
SCIENTIFIC SCORE
Possibly Effective
Based on 26 Researches
7.7
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size:  One (1) Capsule
Amount Per Serving
%DV
Calories
0
 
Total Carbohydrate
0 g
0%+
Total Sugars
0 g
**
Incl. 0 g Added Sugars
 
0%+
Lactobacillus rhamnosus GG
83 mg (20 billion CFUs)
**
Inulin (Chicory root extract)
200 mg
**

Top Medical Research Studies

8
Lactobacillus JB-1 reduces anxiety
Continuous Ingestion of JB-1 during Chronic Stress Ensures Neurometabolic and Behavioural Stability in Rats.
Study indicates probiotic benefits
We explored how the treatment with JB-1—a type of probiotic bacteria—affects anxiety during chronic stress in rats. In our study, half of the twenty rats received JB-1 while the other half got a placebo over eight weeks of stress exposure.

The results were telling! Rats on JB-1 showed less anxiety and were more willing to explore their environment compared to the placebo group, which largely avoided exploration. Additionally, measurements of brain metabolites indicated that JB-1 helped maintain stability in brain chemistry, even in stressful conditions.

This suggests that lactobacillus rhamnosus might play a beneficial role in reducing anxiety during prolonged stress.
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9.5
Inulin reduces anxiety in migraines
A randomized, double-blind, placebo-controlled parallel trial to test the effect of inulin supplementation on migraine headache characteristics, quality of life and mental health symptoms in women with migraine.
Significant effect on anxiety noted.
We conducted a fascinating study to understand how inulin supplementation might affect anxiety levels in women suffering from migraines. By design, this was a randomized, double-blind, placebo-controlled trial involving 80 women aged 20 to 50 years old. Participants received either 10 grams of inulin daily or a placebo for 12 weeks.

Our results showed promising findings regarding anxiety. Specifically, we observed a significant decrease in anxiety levels among those taking inulin, with a reduction of 4.37 points compared to the placebo group. This indicates that inulin may play a role in enhancing mental well-being in those experiencing migraine headaches.

It's worth noting that while we found improvements in anxiety and other mental health symptoms such as stress and depression, the quality of life scores did not show a significant difference between the two groups. This could suggest that while inulin helps with anxiety, it might not immediately influence overall quality of life in women with migraines.

Such findings are encouraging and suggest that inulin supplementation can provide a natural avenue to alleviate some mental health challenges associated with migraine episodes. We believe further research could shed more light on these effects.
Read More
8
Probiotics may reduce anxiety
Lactobacillus rhamnosus GG colonization in early life regulates gut-brain axis and relieves anxiety-like behavior in adulthood.
High relevance for mental health research
We examined how colonizing newborn mice with probiotics, specifically Lactobacillus rhamnosus GG (LGG), influences anxiety in adulthood. By administering live LGG during pregnancy and early life, we observed significant changes to the gut microbiome and protective effects on the intestinal barrier. Notably, the adult mice with LGG colonization showed reduced anxiety-like behaviors in tests designed to measure stress responses. This indicates that early life probiotics could play an important role in regulating the gut-brain axis and improving mental health in later life.
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Most Useful Reviews

8.8
Anxiety relief
It’s true that this product is pricey, but it’s invaluable, especially for those with digestive issues. After my sleeve gastrectomy ten years ago, I suffered from gas and colic when I drank coffee with milk. Taking Riha Takramun on an empty stomach made a significant difference; it eased my stomach discomfort and improved my psychological state. My anxiety diminished as well, although I’m unsure if it’s directly related. Consider exploring holistic medicine, which discusses the importance of resting the intestines and its impact on mental health.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 26 Researches
7.7
9.5
Inulin reduces anxiety in migraines
A randomized, double-blind, placebo-controlled parallel trial to test the effect of inulin supplementation on migraine headache characteristics, quality of life and mental health symptoms in women with migraine.
Significant effect on anxiety noted.
We conducted a fascinating study to understand how inulin supplementation might affect anxiety levels in women suffering from migraines. By design, this was a randomized, double-blind, placebo-controlled trial involving 80 women aged 20 to 50 years old. Participants received either 10 grams of inulin daily or a placebo for 12 weeks.

Our results showed promising findings regarding anxiety. Specifically, we observed a significant decrease in anxiety levels among those taking inulin, with a reduction of 4.37 points compared to the placebo group. This indicates that inulin may play a role in enhancing mental well-being in those experiencing migraine headaches.

It's worth noting that while we found improvements in anxiety and other mental health symptoms such as stress and depression, the quality of life scores did not show a significant difference between the two groups. This could suggest that while inulin helps with anxiety, it might not immediately influence overall quality of life in women with migraines.

Such findings are encouraging and suggest that inulin supplementation can provide a natural avenue to alleviate some mental health challenges associated with migraine episodes. We believe further research could shed more light on these effects.
Read More
9
Probiotics impact anxiety in AD
Ameliorative effects of probiotics in AlCl-induced mouse model of Alzheimer's disease.
High relevance in neurodegeneration
We investigated how probiotics, specifically Lactobacillus rhamnosus and Bifidobacterium BB-12, can affect anxiety in a mouse model of Alzheimer’s disease. In our study, we found that mice treated with these probiotics exhibited significantly reduced anxiety-like behaviors compared to those exposed to aluminum chloride alone.

Through various behavioral tests, it was evident that this probiotic combination also improved memory functions. Our results suggest that leveraging the gut-brain axis through these probiotics could offer a promising approach for alleviating anxiety and cognitive deficits in neurodegenerative conditions like Alzheimer's.
Read More
9
Inulin reduces anxiety in stressed mice
The Influence of Topinambur and Inulin Preventive Supplementation on Microbiota, Anxious Behavior, Cognitive Functions and Neurogenesis in Mice Exposed to the Chronic Unpredictable Mild Stress.
Significant benefits noted
We explored the impact of inulin supplementation on anxiety levels in mice subjected to chronic unpredictable mild stress (CUMS). The study looked at how natural prebiotics, such as topinambur powder and chicory root inulin, influence anxiety and cognitive functions.

Over a period of 10 weeks, we administered inulin alongside topinambur to observe any changes in behavior and neurogenesis compared to a control group. Excitingly, we found that both inulin and topinambur, just like fluoxetine—a known antidepressant—significantly reduced anxiety and depression-like behaviors.

Furthermore, we noted improvements in learning and memory skills for the mice receiving these supplements. Fecal microbiota analysis also revealed that inulin played a role in counteracting stress-induced intestinal disruptions, making it a potentially valuable addition to diets for improving mental health under stress.

Overall, our findings suggest that inulin not only helps mitigate anxiety but also supports cognitive functions during stressful conditions in mice. This shines a light on the potential benefits of prebiotics for mental health.
Read More
8
Lactobacillus rhamnosus shows mixed benefits
Cognitive and Emotional Effect of a Multi-species Probiotic Containing Lactobacillus rhamnosus and Bifidobacterium lactis in Healthy Older Adults: A Double-Blind Randomized Placebo-Controlled Crossover Trial.
Moderate relevance for aging studies
In a randomized double-blind placebo-controlled crossover trial, we investigated whether a multi-species probiotic containing Lactobacillus rhamnosus could help reduce anxiety and improve cognitive function in healthy older adults.

Over a ten-week period, participants consumed the probiotic daily and were assessed for cognitive abilities and emotional well-being.

While significant improvements were found in cognitive and emotional functions, including planning and memory, the study provided limited evidence specifically addressing anxiety benefits.

Therefore, while promising, the role of Lactobacillus rhamnosus for anxiety treatment in older adults remains uncertain.
Read More
8
Lactobacillus Rhamnosus Reduces Anxiety
Effect of Probiotic LB1.5 on Anxiety-like Behavior, Neuroprotection and Neuroinflammation Markers of Male Mice Fed a High-Fat Diet.
Study on probiotic efficacy
We explored how the probiotic LB1.5 influences anxiety-like behaviors in male mice subjected to a high-fat diet. Mice were divided into groups and treated for 13 weeks, with some receiving probiotic supplements.

We found that LB1.5 significantly reduced anxiety-like behaviors in both control and high-fat diet groups. Furthermore, it lowered serum levels of IL-6, an inflammatory marker, in mice on the high-fat diet. Overall, our findings suggest that this probiotic may help mitigate anxiety linked to obesity-related inflammation.
Read More

User Reviews

USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Anxiety relief
It’s true that this product is pricey, but it’s invaluable, especially for those with digestive issues. After my sleeve gastrectomy ten years ago, I suffered from gas and colic when I drank coffee with milk. Taking Riha Takramun on an empty stomach made a significant difference; it eased my stomach discomfort and improved my psychological state. My anxiety diminished as well, although I’m unsure if it’s directly related. Consider exploring holistic medicine, which discusses the importance of resting the intestines and its impact on mental health.
Read More
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