Ginkgo Biloba
9.5
Reduced anxiety
Most Useful Review
Amazing! I have been taking ginkgo for a few months, feeling more energetic and less tired. It seems to help with PMS symptoms, headaches, and even contains powerful antioxidants. I take it in the morning with a meal, and at night with ashwagandha, which calms me and reduces anxiety. I highly recommend it.
9.5
Miraculous effect
Most Useful Review
Along with "Gotu Kola," my experience has been fabulous! I'm 35 with a weight problem and noticed memory issues. After a month of Ginkgo Biloba and Gotu Kola, my capillaries improved and my memory significantly sharpened. It also helped my brother with anxiety and depression. We feel it's a miracle! Start slowly and consult a doctor if necessary.
Peppermint Oil
9.5
Reduces anxiety
Most Useful Review
The scent of peppermint oil soothes and alleviates stress, with a calming effect that helps to ease feelings of anxiety. I truly adore it and wholeheartedly recommend it!
9.5
Helps with anxiety
Most Useful Review
I love mint and sought the perfect aroma to fill my room. This peppermint essential oil is exactly what I wanted. It effectively alleviates anxiety and refreshes the mind. I apply a few drops to a handkerchief for calming inhalation and use it in my hair to promote relaxation. It also helps with headaches and even sore throats. It's a reliable brand in cost-effective packagingāI recommend it for various uses!
Selenium
9.5
Anxiety relief noted
Most Useful Review
I took this for my thyroid, and within a week, I noticed a significant improvement in my mood and disappearance of anxiety.
9.5
Deep sleep achieved
Most Useful Review
Excellent for stress relief and deep sleep. Just one pill taken four hours before bed leads to deep and sound sleep. It effectively addresses stress and anxiety symptoms. I highly recommend it.
Multivitamins
9
Supports stress resilience
Most Useful Review
To manage prolonged stress, adaptogens are essential. The adrenal glands produce hormones like cortisol and adrenaline to combat stress, but constant tension leaves us unwell. Adaptogens help the body endure stress without severe side effects, unlike synthetic drugs. After losing my husband, this combination of adaptogens truly assisted me in coping.
9.5
Calms anxiety effectively
Most Useful Review
During a challenging period of burnout and anxiety at 34, I found this product. The high-quality ingredients, including Rhodiola and Ashwagandha, helped me significantly reduce anxiety and improve sleep. After a week of use, I noticed marked improvements, making this product worth every riyal spent.
5 Htp
9.5
Calmness achieved
Most Useful Review
I am truly grateful for this product! 5-HTP has been invaluable in helping me feel calmer and more balanced, significantly aiding my struggle with anxiety and mood swings.
8.8
Calm after therapy
Most Useful Review
Prescribed by a psychotherapist, it made me calmer, and my anxiety disappeared.
N Acetyl Cysteine Nac
8
Sake yeast shows potential for anxiety
Neurobehavioral protective effects of Japanese sake yeast supplement against chronic stress-induced anxiety and depression-like symptoms in mice: Possible role of central adenosine receptors.
Most Relevant Research
We explored the potential benefits of Japanese sake yeast on anxiety and depression in mice subjected to stress. Over a week, we treated the mice with different doses of sake yeast and assessed its effects on anxiety, mood, and sleep.
Our findings indicated that the yeast improved anxiety and antidepressant-like behaviors, particularly at higher doses. It also increased sleep duration and influenced certain brain levels related to mood. However, the overall results suggest that while sake yeast shows promise, it may not significantly alter all biological markers associated with stress.
Our findings indicated that the yeast improved anxiety and antidepressant-like behaviors, particularly at higher doses. It also increased sleep duration and influenced certain brain levels related to mood. However, the overall results suggest that while sake yeast shows promise, it may not significantly alter all biological markers associated with stress.
9.5
Aids OCD anxiety
Most Useful Review
Results may differ, but NAC worked for my OCD-induced anxiety. I discovered it could be effective for anxiety linked to obsessive-compulsive disorder. I began to feel a calmness enveloping my heart. I now take it daily as a supplement. Iāve tried both Life Extension and Now Foods; both are effective. I often prefer Now, as it contains molybdenum, a mineral crucial for glutathione synthesis, which is rare in standalone supplements.
Arsenicum Album
9.5
Relieves anxiety
Most Useful Review
This is the only supplement that alleviates my anxiety. I never go without it.
9.5
Effective for anxiety
Most Useful Review
I adore this product. It works wonders for my anxiety when combined with deep breathing and relaxation techniques. I wouldnāt want to be without it.
Childrens Herbs
10
Calming remedy
Most Useful Review
This water is a must-have for every household with a baby. It works like magic in soothing anxiety and teething discomfort. I found that the child calms down within 10-15 minutes of taking it. I discarded all other colic remedies, as this one provided us with the tranquillity we needed.
9.5
Reduces anxiety
Most Useful Review
If I had known about this product (and the iHerb website) when my first child was born, winter would not have brought me such anxiety. As a mother of perpetually sick children, I understand the struggle. Echinacea truly works; my older child has been taking it for two years in tablet form, while my younger one takes it in drops. They still catch colds, but symptoms are milder. I also include vitamin C and elderberry. This combination works wonders!
Zinc Magnesium Aspartate
9.5
Helps with sleep
Most Useful Review
Second repurchase. Consuming this truly aids my sleep, alleviates anxiety in a hectic life, and assists my muscles in relaxing after intense training. Itās fantastic.
9.5
Reduces stress
Most Useful Review
This brand is perfect for reducing stress and anxiety, resulting in improved sleep when taken before bedtime.
Alpha Lipoic Acid
8.8
Energy boost noted
Most Useful Review
Nicotinic acid, a water-soluble vitamin, aids in energy production. After a week of taking it, I've noticed improved energy levels and a reduction in fatigue along with relief from stress and anxiety. It has no particular taste, and while I felt slight discomfort initially, it passed quickly.
9.5
Sleep improved quickly
Most Useful Review
I took a magnesium complex with vitamin B6 to address sleep disorders and anxiety. After just one night of taking it, my sleep quality improved significantly. The tablets are somewhat large and tricky to swallow, but the benefits outweigh this minor inconvenience.
Aconitum Napellus
9.5
Enabled outdoor activity
Most Useful Review
Actually helped me after my first dose. I have suffered from agoraphobia for a long time, and I began taking this homeopathic medicine for my fear of the unknown. I have been bedridden due to a chronic back problem for around 35 years. While I tried to maintain normalcy, I also dealt with PTSD, severe depression, and anxiety, making it very challenging. After breaking my ankle last year, I was unable to leave my bed for around seven months. I remembered my earlier experiences with homeopathy and decided to give it another go, aiming to at least go outside. After taking the first dose, I felt a strong urge to try going around the block despite needing a cane, and I realised that focusing on the trees helped lessen my anxiety. I was thrilled to discover that this medicine worked. Thank you to this company for offering it at an affordable price.
9.5
Calms nervous system
Most Useful Review
Wonderful antidote to anxiety. Calms the nervous system.
N Acetyl Glucosamine
9.5
Relaxing for anxiety
Most Useful Review
This product is incredibly relaxing and can make one feel somewhat drowsy, so itās perfect to take before bedtime. I take it twice daily to help manage my high anxiety.
8.3
Effective for anxiety
Most Useful Review
This product is excellent for those who suffer from anxiety; it really does alleviate it. However, it causes constipation for me, which is why I rated it four stars.
Resveratrol
9.5
Reduces anxiety
Most Useful Review
Excellent! It increases sirtuin levels, which helps to lower neurotoxicity. My mood has improved and anxiety is reduced. I'm very satisfied!
9.5
Mitigates anxiety
Most Useful Review
I appreciate that this brand crosses the blood-brain barrier. Resveratrol aids in managing my brain injury, anxiety, and depression, while boosting my energy and overall well-being.
Tea Tree Oil
9.5
Strengthens vitality
Most Useful Review
Tea tree essential oil differs from others as it can be applied pure several times a day to inflamed skin areas. It is recommended for problem skincare, effectively eliminating acne and herpes, while also alleviating allergic skin reactions. It's useful in treating fungal issues and strengthens hair, helping to eliminate dandruff. A good natural repellent, it alleviates itching and swelling from insect bites. Additionally, it is a powerful stimulant of mental activity, enhances vitality, reduces stress, instills self-confidence, relieves anxiety and boosts concentration.
8.8
Relieves anxiety
Most Useful Review
I received the goods safely. I've started using tea tree oil, which aids recovery after stress, enhances concentration, and alleviates anxiety. In cosmetics, it can be part of oil blends to cleanse the skin and alleviate irritation, restore a healthy texture, and even eliminate dandruff. I also use it to combat bad breath, since it is considered a potent natural antiseptic.
Vitamin Bs
8
Niacin helps reduce anxiety symptoms
Antioxidant and neuro-modulatory effects of niacin prevent D-galactose-induced behavioral deficits and memory impairment.
Most Relevant Research
We evaluated the impact of niacin on anxiety and memory loss by examining its effects in male rats exposed to D-galactose, a chemical known to induce behavioral deficits. In our study, we divided the animals into six groups, with some receiving niacin at different doses (25 mg/kg and 50 mg/kg) and others being treated with D-galactose.
Over a two-week period, we observed how niacin influenced their behavior in various tests designed to measure anxiety and depression. After administering niacin, we found that it significantly reduced the anxiety and depressive symptoms that had developed due to D-galactose. This was particularly encouraging as niacin also appeared to support memory function in the rats, showing promise for addressing cognitive decline.
Biochemically, niacin treatment helped restore levels of antioxidant enzymes and neurotransmitters affected by D-galactose, demonstrating its potential to combat oxidative stress and inflammation. Our findings suggest that niacin can act as both an antioxidant and a neuromodulator, offering a valuable approach for treating anxiety and associated cognitive impairments in aging.
Over a two-week period, we observed how niacin influenced their behavior in various tests designed to measure anxiety and depression. After administering niacin, we found that it significantly reduced the anxiety and depressive symptoms that had developed due to D-galactose. This was particularly encouraging as niacin also appeared to support memory function in the rats, showing promise for addressing cognitive decline.
Biochemically, niacin treatment helped restore levels of antioxidant enzymes and neurotransmitters affected by D-galactose, demonstrating its potential to combat oxidative stress and inflammation. Our findings suggest that niacin can act as both an antioxidant and a neuromodulator, offering a valuable approach for treating anxiety and associated cognitive impairments in aging.
8.8
Effective for anxiety
Most Useful Review
Very good product. A little-known fact is that B-1 can significantly help with anxiety and panic, as it reduces lactic acid sensitivity. I take mega doses of over 1500mg daily. I just wish NOW made a 500mg tablet.
Ubiquinol Coq10
9.5
Controlled mood
Most Useful Review
This product is excellent. I have been using it for a long time and noticed positive results quickly, particularly in controlling my mood and anxiety. I highly recommend it.
9
Exceptional energy boost
Most Useful Review
The delivery was on the appointed day, although there was an issue with the delivery agency, which did not notify me when I was not home. They left the package at my gate without warning. The product is exceptional; it energises me throughout the day and doesnāt cause anxiety issues. I've used it for several years, and it's magnificent!
Face Mist
9.5
Helps with anxiety
Most Useful Review
Excellent refresher! This is the best product for a daytime boost or whenever I need a pick-me-up. Itās beneficial for anxiety and also aids with depression. Rosewater from Heritage is the most affordable while maintaining high standards. Itās a staple in my home, safe to use around my service animal and has a lovely, subtle smellānot overpowering. I spray it directly onto my face, even with makeup on, and allow it to dry. A few spritzes help alleviate my PTSD symptoms, and I recommend this to anyone experiencing anxiety issues along with their lavender.
8.8
Soothes anxiety
Most Useful Review
Delicious scent of fresh rose with numerous useful properties! It maintains the pH balance of the skin, combats rashes, and benefits dermatitis and eczema. Additionally, it smoothes, moisturises, nourishes, and renews the skin while healing scars and wounds. The rosewater not only soothes the skin but also alleviates stress and anxiety. It tones the skin with its antibacterial properties and, thanks to its antioxidants, strengthens skin cells and regenerates tissues, revitalising ageing skin. I occasionally use it over makeup, as it removes dryness and tightness!
Probiotics
5
Probiotics did not significantly affect anxiety
Effect of caloric restriction with probiotic supplementation on body composition, quality of life, and psychobiological factors of obese men: A randomized, double-blinded placebo-controlled clinical trial.
Most Relevant Research
We looked into how combining caloric restriction with probiotics affects anxiety in adult men facing obesity. In a well-structured, double-blind, placebo-controlled study, participants followed a 12-week regimen of caloric restriction while taking a specific blend of probiotics.
While we found that anxiety and depressive symptoms improved within the group taking probiotics, there was no significant difference when compared to those on a placebo. This suggests that further research is necessary to fully understand the relationship between probiotics and anxiety in this context.
While we found that anxiety and depressive symptoms improved within the group taking probiotics, there was no significant difference when compared to those on a placebo. This suggests that further research is necessary to fully understand the relationship between probiotics and anxiety in this context.
8.8
Supports focus and calm
Most Useful Review
I use this in my fight against stress. It reduces anxiety, calms me, and increases my concentration and attention. I perceive reality better. The tablets are quite large, but they feel natural and have a pleasant smell. Swallowing is not difficult, and they donāt affect my gastrointestinal tract. The packaging is of high quality and attractive. My endocrinologist recommended Bud as an adaptogen and sedative to relieve stress and normalise my emotional state, as it has a good dosage.
Alpha Gpc
NOW Foods Alpha GPC
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 10 Reviews
8.5
9.5
Reduces anxiety
Most Useful Review
Nootropic properties of Alpha GPC aid in combating apathy and depression, eliminating chronic fatigue, enhancing stress resistance, reducing irritability, and improving mood.
9.5
Boosts confidence
Most Useful Review
After just one 300mg dose in the morning, I felt blissful, joyful, focused, and more confident, with reduced social anxiety. Itās one of the best supplements I've taken, alongside inositol and B Complex. I absolutely love it.
Collagen Supplements
9.5
Boosts mood
Most Useful Review
This product is excellent; it significantly improves mood, sleep, and relieves stress. As a serotonin precursor, it effectively alleviates anxiety. The size is adequate for me, and the quality remains consistently high with premium ingredients. I felt the benefits quickly, and it comes with no taste, which is a plus.
8
Mood improvement
Most Useful Review
Dietary supplements are of good quality with worthwhile ingredients and no smell or taste. They help those with thyroid issues sleep effectively, relieve stress, and normalise mood while reducing anxiety. These supplements also support digestion and muscle health, and help maintain healthy skin with collagen, minerals, and amino acids. They are ideal for individuals aiming to prevent disease and can enhance strength.
Potassium
8.8
Reduced anxiety effectively
Most Useful Review
Fantastic for stress and anxiety. Magtein significantly aids my anxiety and stress, especially when life becomes overwhelming. Currently, I use NowFoods Potassium Gluconate alongside NowFoods Magtein to help stabilise my stress levels.
8.8
Reduced anxiety
Most Useful Review
Excellent for water retention. It balances my electrolytes and helps with anxiety, improving my sleep.
Childrens Health
9.5
Calms discomfort
Most Useful Review
I purchased Mommy's Bliss simethicone drops for my newborn, and they really have been a lifesaver. Initially, our baby experienced gas formation that caused discomfort and anxiety, prompting me to try these drops. Theyāre suitable for newborns and have a neutral taste, making them easy to mix with milk or water. After the first use, our baby seemed calmer, and his tummy issues reduced. The drops effectively relieve gas, allowing us to enjoy peaceful nights. The 30 ml packaging is convenient and lasts quite long. I feel assured giving my child this safe remedy. I highly recommend Mommy's Bliss for any parent facing gas-related issues with their baby.
10
Eliminates anxiety symptoms
Most Useful Review
The child is three months old and has been suffering from colic, but thanks to this medication, all symptoms of anxiety have vanished.
St Johns Wort
8
Hypericum perforatum alleviates post-MI anxiety
Antidepressant and Cardioprotective Effects of Self-Nanoemulsifying Self-Nanosuspension Loaded with Hypericum perforatum on Post-Myocardial Infarction Depression in Rats.
Most Relevant Research
We investigated the effects of Hypericum perforatum, commonly known as St. John's Wort, on anxiety that follows a heart attack. Our research focused on measuring how this herbal treatment could help in not just relieving anxiety, but also improving heart functions after a myocardial infarction (MI).
To enhance the absorption and efficacy of HP, we formulated it into a self-nanoemulsifying self-nanosuspension (HP.SNESNS). In our study, we used a group of rats that had experienced MI and observed that HP.SNESNS significantly reduced anxiety and depressive-like behaviors, alongside cognitive dysfunction.
Notably, it increased levels of essential neurotransmitters like norepinephrine and serotonin in the brain, which are known to play a vital role in mood regulation. Additionally, we found that HP.SNESNS helped protect heart tissues by reducing inflammation markers and restoring heart architecture. Overall, these improvements were comparable to those seen with higher doses of unformulated HP.
In conclusion, our findings indicate that HP.SNESNS not only helps manage anxiety in a post-MI context but also offers cardio-protective benefits, making it a promising candidate for further research.
To enhance the absorption and efficacy of HP, we formulated it into a self-nanoemulsifying self-nanosuspension (HP.SNESNS). In our study, we used a group of rats that had experienced MI and observed that HP.SNESNS significantly reduced anxiety and depressive-like behaviors, alongside cognitive dysfunction.
Notably, it increased levels of essential neurotransmitters like norepinephrine and serotonin in the brain, which are known to play a vital role in mood regulation. Additionally, we found that HP.SNESNS helped protect heart tissues by reducing inflammation markers and restoring heart architecture. Overall, these improvements were comparable to those seen with higher doses of unformulated HP.
In conclusion, our findings indicate that HP.SNESNS not only helps manage anxiety in a post-MI context but also offers cardio-protective benefits, making it a promising candidate for further research.
9.5
No more anxiety
Most Useful Review
I have a family history of depression and noticed signs in myself at 35. Prescription medications didn't work and caused anxiety. I tried St. John's Wort, discarding my prescriptions. After 15 years, Iām depression-free and quite mellow without anxiety attacks from ineffective drugs. I take two in the morning and one at noon, satisfied with Now Foods' quality and price.
Tulsi Tea
9
DHA reduces anxiety risk
Plasma Polyunsaturated Fatty Acid Levels and Mental Health in Middle-Aged and Elderly Adults.
Most Relevant Research
We explored the potential benefits of docosahexaenoic acid (DHA) in reducing anxiety among middle-aged and elderly adults. This was part of a larger study involving over 102,000 participants, where we assessed the impact of various polyunsaturated fatty acids (PUFAs) on mental health conditions, including anxiety and depression.
Our findings indicated that higher plasma levels of DHA, as well as omega-3 PUFAs in general, were linked to a lower risk of developing anxiety disorders. Specifically, we noted that participants in the highest quartile of PUFA levels, including DHA, showed a 14% reduction in the hazard of incident anxiety compared to those in the lowest quartile.
Further analysis of psychological symptoms revealed that those with elevated omega-3 PUFA levels, prominently DHA, experienced fewer adverse mental health issues. While we also considered white matter microstructures through neuroimaging with a subgroup of participants, the specific mechanisms behind DHA's positive effects on anxiety remain an area for future research.
Our findings indicated that higher plasma levels of DHA, as well as omega-3 PUFAs in general, were linked to a lower risk of developing anxiety disorders. Specifically, we noted that participants in the highest quartile of PUFA levels, including DHA, showed a 14% reduction in the hazard of incident anxiety compared to those in the lowest quartile.
Further analysis of psychological symptoms revealed that those with elevated omega-3 PUFA levels, prominently DHA, experienced fewer adverse mental health issues. While we also considered white matter microstructures through neuroimaging with a subgroup of participants, the specific mechanisms behind DHA's positive effects on anxiety remain an area for future research.
9.5
Reduced anxiety levels
Most Useful Review
Our family adores this tea! The Tulsi Ashwagandha has a lovely aroma. After using it in courses, I noticed a significant reduction in anxiety, allowing me to handle stress much more calmly. My libido has also improved; Ashwagandha works wonders for it.
Ashwagandha
9
DHA reduces anxiety risk
Plasma Polyunsaturated Fatty Acid Levels and Mental Health in Middle-Aged and Elderly Adults.
Most Relevant Research
We explored the potential benefits of docosahexaenoic acid (DHA) in reducing anxiety among middle-aged and elderly adults. This was part of a larger study involving over 102,000 participants, where we assessed the impact of various polyunsaturated fatty acids (PUFAs) on mental health conditions, including anxiety and depression.
Our findings indicated that higher plasma levels of DHA, as well as omega-3 PUFAs in general, were linked to a lower risk of developing anxiety disorders. Specifically, we noted that participants in the highest quartile of PUFA levels, including DHA, showed a 14% reduction in the hazard of incident anxiety compared to those in the lowest quartile.
Further analysis of psychological symptoms revealed that those with elevated omega-3 PUFA levels, prominently DHA, experienced fewer adverse mental health issues. While we also considered white matter microstructures through neuroimaging with a subgroup of participants, the specific mechanisms behind DHA's positive effects on anxiety remain an area for future research.
Our findings indicated that higher plasma levels of DHA, as well as omega-3 PUFAs in general, were linked to a lower risk of developing anxiety disorders. Specifically, we noted that participants in the highest quartile of PUFA levels, including DHA, showed a 14% reduction in the hazard of incident anxiety compared to those in the lowest quartile.
Further analysis of psychological symptoms revealed that those with elevated omega-3 PUFA levels, prominently DHA, experienced fewer adverse mental health issues. While we also considered white matter microstructures through neuroimaging with a subgroup of participants, the specific mechanisms behind DHA's positive effects on anxiety remain an area for future research.
10
Remarkable mood enhancement
Most Useful Review
After two months of daily use, ashwagandha reduced my stress and anxiety significantly, improving my mood and overall stamina. It also increased my sense of enjoyment in life and my sexual desire. Highly recommend based on my positive experience.
Zinc
7
Zinc alleviates acrylamide-induced anxiety
Zinc Ameliorates Acrylamide-Induced Cognitive Impairment in Male Wistar Rats: Modulation of Oxidative Stress, Neuro-inflammation, and Neurotrophic Pathways.
Most Relevant Research
We explored the effects of zinc treatment on anxiety caused by exposure to acrylamide, a harmful chemical found in some foods that can lead to cognitive decline and emotional distress. In our study, twenty male Wistar rats were divided into four groups; one group received water, while the other groups were given a daily oral dose of acrylamide.
Among those exposed to acrylamide, some were treated with low and high doses of zinc for eight weeks. We observed that zinc significantly improved anxiety-like behavior in the treated groups. This suggests that zinc acts not only as a protector against cognitive impairment but also helps in alleviating anxiety symptoms associated with acrylamide exposure.
Furthermore, zinc demonstrated antioxidant and anti-inflammatory effects, which could contribute to its ability to improve mood and mental function. Overall, zinc emerged as a promising contender in mitigating anxiety and cognitive challenges posed by acrylamide, leading to better mental clarity and emotional well-being.
Among those exposed to acrylamide, some were treated with low and high doses of zinc for eight weeks. We observed that zinc significantly improved anxiety-like behavior in the treated groups. This suggests that zinc acts not only as a protector against cognitive impairment but also helps in alleviating anxiety symptoms associated with acrylamide exposure.
Furthermore, zinc demonstrated antioxidant and anti-inflammatory effects, which could contribute to its ability to improve mood and mental function. Overall, zinc emerged as a promising contender in mitigating anxiety and cognitive challenges posed by acrylamide, leading to better mental clarity and emotional well-being.
9.5
Reduced anxiety
Most Useful Review
This vitamin has significantly helped me with my anxiety and depression over the past year. Taking it consistently has made a considerable difference. I highly recommend this vitamin to anyone struggling with mental health or not feeling their best.
Vitamin D
8
High-dose vitamin D reduces anxiety
Effects of an 8-week high-dose vitamin D supplementation on fatigue and neuropsychiatric manifestations in post-COVID syndrome: A randomized controlled trial.
Most Relevant Research
We conducted a study to understand how high-dose vitamin D supplementation might impact anxiety levels, particularly in patients experiencing post-COVID symptoms. In our double-blind, randomized controlled trial, we enrolled 80 individuals dealing with fatigue or neuropsychiatric issues after COVID-19.
Participants were split into two groups: one received a weekly dose of 60,000 IU of vitamin D, while the other group received a placebo. Over eight weeks, we evaluated various outcomes, including anxiety levels using the Depression, Anxiety, and Stress Scale (DASS-21).
The results were encouraging for the vitamin D group. We observed significant improvements in anxiety levels, with a notable reduction reported by participants. However, other measures related to sleep quality, depression, cognitive function, and inflammatory markers did not show similar significant changes.
Importantly, we found that the vitamin D group reported no serious adverse effects, indicating that this supplementation is generally safe. These findings suggest that high-dose vitamin D may offer substantial benefits for anxiety relief in patients recovering from COVID-19, albeit with limited effects on other symptoms.
Participants were split into two groups: one received a weekly dose of 60,000 IU of vitamin D, while the other group received a placebo. Over eight weeks, we evaluated various outcomes, including anxiety levels using the Depression, Anxiety, and Stress Scale (DASS-21).
The results were encouraging for the vitamin D group. We observed significant improvements in anxiety levels, with a notable reduction reported by participants. However, other measures related to sleep quality, depression, cognitive function, and inflammatory markers did not show similar significant changes.
Importantly, we found that the vitamin D group reported no serious adverse effects, indicating that this supplementation is generally safe. These findings suggest that high-dose vitamin D may offer substantial benefits for anxiety relief in patients recovering from COVID-19, albeit with limited effects on other symptoms.
9.5
Reduced anxiety
Most Useful Review
I have been taking this vitamin for over a month now, and I have noticed significant improvements in my quality of life. I used to frequently suffer from anxiety and depression, but since using this supplement, those symptoms have vanished.
L Lysine
8
Anxiety reduction observed with lysine
Anxiolytic, anti-nociceptive and body weight reducing effects of L-lysine in rats: Relationship with brain serotonin an In-Vivo and In-Silico study.
Most Relevant Research
We investigated how L-lysine, an essential amino acid, influences anxiety and body weight. The study involved administering two doses of L-lys to rats over 20 days.
We found that while L-lys didn't affect food intake, it did lead to weight reduction and showed signs of anxiolytic effects on the first day. Notably, repeated doses increased serotonin levels in key brain areas, which may explain its calming effects.
However, the study's outcomes indicate that L-lys may not dramatically alter anxiety compared to other treatments.
We found that while L-lys didn't affect food intake, it did lead to weight reduction and showed signs of anxiolytic effects on the first day. Notably, repeated doses increased serotonin levels in key brain areas, which may explain its calming effects.
However, the study's outcomes indicate that L-lys may not dramatically alter anxiety compared to other treatments.
9.5
Alleviates anxiety successfully
Most Useful Review
After taking this for several months during winter and early spring, I remained healthy, even avoiding a runny nose, which I had considered a fantasy. I've spent years in a constant state of anxiety, yet after stopping the medication, I realised how anxious I had been. Remarkably, for four months on this drug, I forgot what feeling anxious was like. It not only boosts immunity but significantly alleviates anxiety too. I experienced no drowsiness, only calmness.
Evening Primrose Oil
8
Evening primrose oil moderately effective
Psychological Assessment and Treatment Effectiveness in Mastalgia: Developing a Treatment Algorithm.
Most Relevant Research
In our exploration of treatment options for mastalgia, we focused on the effectiveness of evening primrose oil combined with vitamin E. Conducted at King George's Medical University, the study assessed 106 female patients suffering from breast pain.
We measured psychological status using the DASS-42 scale and pain using a visual analog scale. While topical NSAIDs showed a strong response rate, evening primrose oil and vitamin E had a notable effect in 6.98% of patients.
Overall, both treatments proved valuable, though we found no correlation between psychological conditions and pain severity.
We measured psychological status using the DASS-42 scale and pain using a visual analog scale. While topical NSAIDs showed a strong response rate, evening primrose oil and vitamin E had a notable effect in 6.98% of patients.
Overall, both treatments proved valuable, though we found no correlation between psychological conditions and pain severity.
8.8
Significant relief noted
Most Useful Review
The capsules are quite large and can be challenging to swallow; however, they're worth the effort! They have greatly helped to normalise my emotional state, improved restful sleep without anxiety or sweating, and significantly reduced hot flashes. I've previously tried other natural products, but their effects were weaker due to lower active ingredients. This specific formulation, containing 1300 active substances, suits me and has noticeably improved my skin hydration as well! After just a week, I could see a difference. I'm definitely ordering more from this company, as this truly effective product has transformed my wellbeing.
Fiber
8.8
Positive anxiety relief
Most Useful Review
For a long time, I researched various vitamin B complex brands before choosing this one, and I have no regrets. These vitamins positively affect the nervous system, improving sleep, reducing anxiety, and helping to combat stress. They work best in combination as they enhance each other's effects. The dosages are high for quick replenishment, and the bright yellow urine is a normal bodily reaction. My whole family takes them, and we are very satisfied with the results. I highly recommend them.
8.8
Normalised blood pressure
Most Useful Review
Magnesium B6 was prescribed by a neurologist for my mother to combat stress. After just two months, she became calm, positive, and the pressure stabilised. This supplement helped eliminate anxiety and insomnia, normalising her condition without needing additional medications. Cardiologists suggest a daily intake of 400-600 mg of magnesium, which I found beneficial for managing hypertension.
Chamomile Tea
7.8
Natural stress relief
Most Useful Review
This Chamomile is of high quality and far cleaner than that found in Al-Attarin. I use it as a natural sedative for sleep disorders and anxiety, and it has various immunity benefits, particularly for those suffering from pre-menstrual symptoms.
9.5
Anxiety recovery noted
Most Useful Review
My daily favourite, Chamomile, is essential for calming my stomach due to ulcers and inflammation. Iāve been drinking it for a year now, and it has alleviated my bloating and gastric issues. After a month of consuming it, my ulcer healed completely. Furthermore, I no longer experience anxiety. I highly recommend drinking it regularly and keeping faith.
Vitamins
8
Vitamin C alleviates anxiety in autism
Vitamin C and Gallic Acid Ameliorate Motor Dysfunction, Cognitive Deficits, and Brain Oxidative Stress in a Valproic Acid-Induced Model of Autism.
Most Relevant Research
We set out to explore how vitamin C influences anxiety-like behaviors in a model of autism caused by valproic acid (VPA). In our study, we used fourteen female rats that underwent specific treatments to induce autism in their offspring. After a period of observation, we treated male pups with daily injections of vitamin C for four weeks. Then, we assessed their behavior to see if there were any changes in anxiety levels.
Our findings suggested that vitamin C significantly reduced anxiety-like behaviors in these rats. This outcome is particularly promising considering that autism often brings associated anxiety. By measuring various brain oxidative stress markers, we also noted improvements in mental functioning and motor skills after vitamin C treatment. Overall, our work underscores the potential benefits of vitamin C as a supportive treatment for anxiety-related issues in autism, indicating a pathway for future research and therapeutic strategies.
Our findings suggested that vitamin C significantly reduced anxiety-like behaviors in these rats. This outcome is particularly promising considering that autism often brings associated anxiety. By measuring various brain oxidative stress markers, we also noted improvements in mental functioning and motor skills after vitamin C treatment. Overall, our work underscores the potential benefits of vitamin C as a supportive treatment for anxiety-related issues in autism, indicating a pathway for future research and therapeutic strategies.
9.5
Enhances well-being
Most Useful Review
An excellent supplement that improves well-being. It alleviates anxiety and promotes cheerfulness and a good mood.
Acetyl L Carnitine
7
ALC shows limited anxiety benefits
Effect of acetyl-L-carnitine on hypersensitivity in acute recurrent caerulein-induced pancreatitis and microglial activation along the brain's pain circuitry.
Most Relevant Research
We aimed to assess how acetyl-L-carnitine (ALC) affects pain and anxiety linked to acute pancreatitis in a mouse model. Over several weeks, mice received injections to induce pancreatitis, and then were treated with ALC.
Results showed that while ALC reduced certain types of pain sensitivity, it did not seem to alleviate the anxiety-like behaviors associated with the condition. This indicates that ALC may not effectively treat anxiety related to acute pancreatitis.
Results showed that while ALC reduced certain types of pain sensitivity, it did not seem to alleviate the anxiety-like behaviors associated with the condition. This indicates that ALC may not effectively treat anxiety related to acute pancreatitis.
9.5
Reduced social fear
Most Useful Review
Six stars out of five! This is the best supplement I've used so far. It significantly reduces stress and improves mood, making it ideal for anyone facing social anxiety or fear of public speaking.
L Taurine
8
Taurine reduces anxiety in mice
Long-term taurine supplementation regulates brain mitochondrial dynamics in mice.
Most Relevant Research
We looked into how taurine, a common amino acid found in the brain, affects anxiety levels. Young mice were given different concentrations of taurine (0.25%, 0.5%, and 1%) in their drinking water for six months to see its potential benefits on memory, cognition, and mood.
Throughout the study, we observed that taurine had a significant effect on improving memory performance and reducing signs of anxiety and depression-like behavior in the mice. In addition to these behavioral changes, taurine also appeared to enhance mitochondrial function, which plays a crucial role in energy and cell health within the brain.
Interestingly, we found no significant difference in anxiety reduction between the various doses of taurine. This suggests that even lower amounts of taurine may be effective. Overall, our findings point towards taurine's potential as a therapeutic option for addressing anxiety and related neurological issues, although further research in humans is necessary to confirm these results.
Throughout the study, we observed that taurine had a significant effect on improving memory performance and reducing signs of anxiety and depression-like behavior in the mice. In addition to these behavioral changes, taurine also appeared to enhance mitochondrial function, which plays a crucial role in energy and cell health within the brain.
Interestingly, we found no significant difference in anxiety reduction between the various doses of taurine. This suggests that even lower amounts of taurine may be effective. Overall, our findings point towards taurine's potential as a therapeutic option for addressing anxiety and related neurological issues, although further research in humans is necessary to confirm these results.
9.5
Anxiety relief
Most Useful Review
Taking this every night helps me manage my anxious feelings and nervous stomach. It works quickly, and I often combine it with magnesium malate, resulting in a calm state. The powder mixes easily with water and has no taste. I will definitely purchase it again as it is effective for me.
Phosphatidylserine
8
Phosphatidylserine lowers stress responses
Effects of soy lecithin phosphatidic acid and phosphatidylserine complex (PAS) on the endocrine and psychological responses to mental stress.
Most Relevant Research
In our study, we looked at how phosphatidylserine supplementation affects mood and stress responses during an anxiety-inducing situation. Participants were divided into four groups, receiving different doses of phosphatidylserine before facing a mental stress test.
We found that the group receiving 400 mg of phosphatidylserine experienced lower stress hormone levels and reported feeling less distressed. However, larger doses did not bring the same benefits, indicating that the 400 mg dosage might be key in alleviating anxiety during stress.
These findings suggest that phosphatidylserine could be a promising option for managing stress-related issues.
We found that the group receiving 400 mg of phosphatidylserine experienced lower stress hormone levels and reported feeling less distressed. However, larger doses did not bring the same benefits, indicating that the 400 mg dosage might be key in alleviating anxiety during stress.
These findings suggest that phosphatidylserine could be a promising option for managing stress-related issues.
9.5
Calms anxiety effectively
Most Useful Review
Effective immediately, one tablet is great for anxiety feelings before stressful encounters. It alleviates waves of anger and sadness. I tried both capsule and tablet forms and found both work equally well. Although priced high, Iām concerned about low-cost options affecting its effectiveness.
Calcium Magnesium
8
Calcium blockers reduce cocaine withdrawal anxiety
L-type calcium channel blockade attenuates the anxiogenic-like effects of cocaine abstinence in female and male rats.
Most Relevant Research
We explored how blocking L-type calcium channels (LTCCs) could influence anxiety-like behaviors during cocaine abstinence in both female and male rats. In this study, rats were trained to self-administer cocaine or saline, followed by a two-week abstinence period. Throughout this withdrawal phase, we examined their behavior using several tests designed to measure anxiety and mood, notably the elevated plus maze and forced swim test, while also checking for changes in their preference for a sweet solution.
Our findings revealed that cocaine-abstinent rats exhibited increased anxiety, as indicated by reduced time spent in open arms of the maze and heightened immobility in the forced swim test. Administering isradipineāa calcium channel blockerācould reverse some anxiety-like behaviors, with varied efficacy based on sex and dosage. For instance, the lower dose effectively reduced anxiety in female rats, while males required a higher dose to obtain similar results. In terms of immobility during stress tests, both sexes benefited from the lower dose of isradipine, while the higher dose affected both groups regardless of their abstinence condition.
This research emphasizes the potential of LTCCs in managing mood-related symptoms linked to cocaine abstinence, though results suggest a more complex relationship that requires further investigation. Overall, our study presents a hopeful look at calcium channel blockade as a possible avenue for treating anxiety disorders that may arise from substance withdrawal.
Our findings revealed that cocaine-abstinent rats exhibited increased anxiety, as indicated by reduced time spent in open arms of the maze and heightened immobility in the forced swim test. Administering isradipineāa calcium channel blockerācould reverse some anxiety-like behaviors, with varied efficacy based on sex and dosage. For instance, the lower dose effectively reduced anxiety in female rats, while males required a higher dose to obtain similar results. In terms of immobility during stress tests, both sexes benefited from the lower dose of isradipine, while the higher dose affected both groups regardless of their abstinence condition.
This research emphasizes the potential of LTCCs in managing mood-related symptoms linked to cocaine abstinence, though results suggest a more complex relationship that requires further investigation. Overall, our study presents a hopeful look at calcium channel blockade as a possible avenue for treating anxiety disorders that may arise from substance withdrawal.
8.8
Heart health improvement
Most Useful Review
For the heart, this is excellent! I consumed all 250 tablets, and the effect was immediate. My heart rate normalised, with tachycardia disappearing. It alleviates stress and anxiety, and now I take it as required. I am very satisfied with the medication.
Dha
9
DHA reduces anxiety risk
Plasma Polyunsaturated Fatty Acid Levels and Mental Health in Middle-Aged and Elderly Adults.
Most Relevant Research
We explored the potential benefits of docosahexaenoic acid (DHA) in reducing anxiety among middle-aged and elderly adults. This was part of a larger study involving over 102,000 participants, where we assessed the impact of various polyunsaturated fatty acids (PUFAs) on mental health conditions, including anxiety and depression.
Our findings indicated that higher plasma levels of DHA, as well as omega-3 PUFAs in general, were linked to a lower risk of developing anxiety disorders. Specifically, we noted that participants in the highest quartile of PUFA levels, including DHA, showed a 14% reduction in the hazard of incident anxiety compared to those in the lowest quartile.
Further analysis of psychological symptoms revealed that those with elevated omega-3 PUFA levels, prominently DHA, experienced fewer adverse mental health issues. While we also considered white matter microstructures through neuroimaging with a subgroup of participants, the specific mechanisms behind DHA's positive effects on anxiety remain an area for future research.
Our findings indicated that higher plasma levels of DHA, as well as omega-3 PUFAs in general, were linked to a lower risk of developing anxiety disorders. Specifically, we noted that participants in the highest quartile of PUFA levels, including DHA, showed a 14% reduction in the hazard of incident anxiety compared to those in the lowest quartile.
Further analysis of psychological symptoms revealed that those with elevated omega-3 PUFA levels, prominently DHA, experienced fewer adverse mental health issues. While we also considered white matter microstructures through neuroimaging with a subgroup of participants, the specific mechanisms behind DHA's positive effects on anxiety remain an area for future research.
9.5
Psychological relief
Most Useful Review
Remarkable effects! After rapid weight loss, I faced anxiety and panic attacks. Within a week of taking DHA, I felt normal again without any adverse symptoms. NOW's quality is outstanding and crucial for my health.
Lactobacillus
5
Probiotic effects on anxiety limited
Effect of caloric restriction with probiotic supplementation on body composition, quality of life, and psychobiological factors of obese men: A randomized, double-blinded placebo-controlled clinical trial.
Most Relevant Research
We conducted a clinical trial aimed at understanding the effect of caloric restriction combined with probiotic supplementation on various health factors, including anxiety, in obese men.
After 12 weeks, while the probiotic had no additional benefit on body composition or overall quality of life, we noted improvements in anxiety and depressive symptoms among those who received the probiotics.
However, there were no significant differences between the groups overall, suggesting that more research is necessary to fully understand this relationship.
After 12 weeks, while the probiotic had no additional benefit on body composition or overall quality of life, we noted improvements in anxiety and depressive symptoms among those who received the probiotics.
However, there were no significant differences between the groups overall, suggesting that more research is necessary to fully understand this relationship.
9.5
Improved mood
Most Useful Review
Excellent! I suffered from mild depression and anxiety for a long time but struggled to find the right antidepressants until I started taking this. Initially, I wanted it for an energy and immunity boost, but now on my third bottle, my mood has significantly improved!
Turmeric Curcumin
8
Curcumin shows potential for anxiety relief
Decreased Systemic Monocyte Colony Protein-1 (MCP-1) Levels and Reduced sCD14 Levels in Curcumin-Treated Patients with Moderate Anxiety: A Pilot Study.
Most Relevant Research
We evaluated whether curcumin, a compound found in turmeric, can help reduce anxiety and improve immune system responses. In this study, 81 individuals were divided into two groups: a control group without anxiety and a group experiencing moderate anxiety. The anxious participants took curcumin supplements for 15 days, receiving 1800 mg per day.
Our findings showed that those with anxiety had elevated levels of certain inflammatory markers and cortisol, a stress hormone. After curcumin treatment, the levels of these markers, particularly MCP-1 and sCD14, decreased significantly. This was promising, as it suggests that curcumin not only helps lower anxiety symptoms but also reduces inflammation and oxidative stress in the body.
Overall, we observed that curcumin may have protective effects against anxiety by balancing various bodily responses. However, it's important to note that while the results are encouraging, more extensive studies are needed to fully understand how curcumin impacts anxiety and inflammation.
Our findings showed that those with anxiety had elevated levels of certain inflammatory markers and cortisol, a stress hormone. After curcumin treatment, the levels of these markers, particularly MCP-1 and sCD14, decreased significantly. This was promising, as it suggests that curcumin not only helps lower anxiety symptoms but also reduces inflammation and oxidative stress in the body.
Overall, we observed that curcumin may have protective effects against anxiety by balancing various bodily responses. However, it's important to note that while the results are encouraging, more extensive studies are needed to fully understand how curcumin impacts anxiety and inflammation.
9.5
Reduces anxiety effectively
Most Useful Review
If you suffer from inflammation or pain, this supplement is essential. Curcumin, shown to be as effective as ibuprofen, is a key addition for my joint pain and headaches. It may also alleviate anxiety if linked to inflammation. I double my dose when feeling unwell, and it noticeably speeds up recovery from infections.
Vitamin B Complex
7
Vitamin B may alleviate anxiety symptoms
[Effects of Vitamin B on Behaviors, Brain Monoamine Neurotransmitters, and Brain-Derived Neurotrophic Factor in Depressive Rats].
Most Relevant Research
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.
The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
8.8
Positive anxiety relief
Most Useful Review
For a long time, I researched various vitamin B complex brands before choosing this one, and I have no regrets. These vitamins positively affect the nervous system, improving sleep, reducing anxiety, and helping to combat stress. They work best in combination as they enhance each other's effects. The dosages are high for quick replenishment, and the bright yellow urine is a normal bodily reaction. My whole family takes them, and we are very satisfied with the results. I highly recommend them.
Prebiotic Fiber Inulin
8
Inulin's timing impacts anxiety relief
Administration time modify the anxiolytic and antidepressant effects of inulin via gut-brain axis.
Most Relevant Research
We investigated how inulin, a type of dietary fiber, can influence anxiety and depression, particularly through its interaction with the gut-brain axis. Our research showed that the timing of inulin consumption significantly affects its ability to alleviate anxiety and depression-like behaviors induced by chronic unpredictable mild stress (CUMS).
Through fecal microbiota transplantation, we confirmed that when inulin is taken at different times, it produces varying effects on anxiety levels. Notably, administering inulin in the evening had a more pronounced impact on reducing inflammation compared to taking it in the morning.
Moreover, metabolomic analysis revealed that certain metabolites, such as fenofibric acid and 4'-Hydroxyfenoprofen glucuronide, could play crucial roles in these effects. Overall, our findings suggest that evening inulin consumption not only improves inflammation but also enhances amino acid metabolism, highlighting the importance of timing in nutritional interventions for anxiety relief.
Through fecal microbiota transplantation, we confirmed that when inulin is taken at different times, it produces varying effects on anxiety levels. Notably, administering inulin in the evening had a more pronounced impact on reducing inflammation compared to taking it in the morning.
Moreover, metabolomic analysis revealed that certain metabolites, such as fenofibric acid and 4'-Hydroxyfenoprofen glucuronide, could play crucial roles in these effects. Overall, our findings suggest that evening inulin consumption not only improves inflammation but also enhances amino acid metabolism, highlighting the importance of timing in nutritional interventions for anxiety relief.
9.5
Brain clarity regained
Most Useful Review
There is a noticeable result! I had colon issues and began taking a teaspoon of inulin each day with green tea, which was delightfulālike childhood toffee. I soon increased it to two teaspoons, and the entire jar was gone within weeks. The effects were almost immediate: my stool improved, and bloating and flatulence vanished. As a bonus, my mental clarity improved, and my anxiety diminished. My mood has brightened significantly! I will certainly purchase more.
L Theanine
8
L-theanine reduces anxiety effectively
Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
Most Relevant Research
We explored the impact of L-theanine and GABA on anxiety levels in preoperative surgical patients. In a randomized controlled study involving 168 participants, we compared the effects of these amino acids with that of a common sedative, alprazolam.
Our findings showed that both L-theanine and GABA effectively reduced preoperative anxiety while causing minimal sedation and even enhancing cognitive performance. This suggests that L-theanine might be a safe alternative to traditional anxiolytics for managing anxiety before surgery.
Our findings showed that both L-theanine and GABA effectively reduced preoperative anxiety while causing minimal sedation and even enhancing cognitive performance. This suggests that L-theanine might be a safe alternative to traditional anxiolytics for managing anxiety before surgery.
9.5
Calmness achieved
Most Useful Review
Iāve noticed very positive effects; I cope with anxiety better, feel more confident, and remain calm. It positively influences my mood and helps concentration without causing drowsiness. I take it regularly; its effect is similar to that of good tea. I highly recommend it to everyone.
Coenzyme Q10 Coq10
7
Q10 and ultrasound improve anxiety
Low-intensity pulsed ultrasound enhances delivery of 30Ā nm Q10 for improving mental and memory disorder in APP/PS1 mice.
Most Relevant Research
We explored the potential of coenzyme Q10 (Q10) in alleviating anxiety and depression in a mouse model of Alzheimer's disease. The study involved APPswe/PS1dE9 mice that received either Q10 or a combination of Q10 and low-intensity pulsed ultrasound (LIPUS). The latter approach aimed to enhance the delivery of Q10 through the blood-brain barrier, which is crucial since many treatments struggle to reach the brain effectively.
Our findings indicated that combining Q10 with LIPUS significantly improved anxiety-like and depression-like behaviors in these mice compared to Q10 alone. With the optimal intensity of LIPUS, the treatment led to increased levels of serotonin and dopamine in the brain, while also reducing harmful substances like formaldehyde and protein plaques associated with Alzheimerās.
However, we must note that despite these encouraging results, the effectiveness of the LIPUS treatment, particularly at varying intensities, only partially addressed anxiety and memory issues. Thus, while this combination therapy holds promise, it is clear that more research is necessary to understand how Q10 alone impacts anxiety effectively, especially without the influence of LIPUS.
Our findings indicated that combining Q10 with LIPUS significantly improved anxiety-like and depression-like behaviors in these mice compared to Q10 alone. With the optimal intensity of LIPUS, the treatment led to increased levels of serotonin and dopamine in the brain, while also reducing harmful substances like formaldehyde and protein plaques associated with Alzheimerās.
However, we must note that despite these encouraging results, the effectiveness of the LIPUS treatment, particularly at varying intensities, only partially addressed anxiety and memory issues. Thus, while this combination therapy holds promise, it is clear that more research is necessary to understand how Q10 alone impacts anxiety effectively, especially without the influence of LIPUS.
10
Increased energy
Most Useful Review
Energy charge! I bought this dietary supplement to enhance my performance, especially after covid. On the third week, I felt more energetic, waking up easily with one alarm. My productivity improved, and I felt less fatigued. My anxiety diminished and my mood stabilised. My light tachycardia is gone, and my recovery from gym sessions has improved. Q10 is essential for everyone, as its production decreases with ageāsuggesting it should be supplemented. I hope this review helps!
B6 Pyridoxine
9
Vitamin B6 potentially reduces anxiety
Mental Health Conditions, Including Depression and Stress, Are Associated with Increased Odds of Gastric Cancer-Insights into the Role of Diet: A Case-Control Study.
Most Relevant Research
Our investigation aimed to understand how vitamin B6 might influence anxiety, particularly among individuals facing mental health challenges like depression and stress. We assessed the mental health of 82 gastric cancer patients compared to 95 healthy individuals, using a questionnaire that evaluated their levels of anxiety and depression.
Interestingly, our findings showed a noteworthy link between vitamin B6 intake and decreased anxiety levels among those with depression. Specifically, vitamin B6 emerged as a significant protective factor, suggesting that higher intake could help reduce anxiety symptoms. This trend underscores the potential importance of certain dietary choices in managing mental health.
Our study also highlighted that other dietary factors could affect mental health. For instance, sugar and salt were found to increase anxiety risks, while foods rich in vitamins, minerals, and phytochemicals were associated with lower incidences of stress and depression. This points to the broader picture that healthy eating patterns may assist in fostering mental well-being and, in turn, impact conditions like gastric cancer.
However, while these initial findings are promising, we acknowledge the need for further research to fully understand these relationships and the underlying mechanisms involved. The interplay between diet, mental health, and physical health, such as cancer risks, is complex and warrants deeper exploration.
Interestingly, our findings showed a noteworthy link between vitamin B6 intake and decreased anxiety levels among those with depression. Specifically, vitamin B6 emerged as a significant protective factor, suggesting that higher intake could help reduce anxiety symptoms. This trend underscores the potential importance of certain dietary choices in managing mental health.
Our study also highlighted that other dietary factors could affect mental health. For instance, sugar and salt were found to increase anxiety risks, while foods rich in vitamins, minerals, and phytochemicals were associated with lower incidences of stress and depression. This points to the broader picture that healthy eating patterns may assist in fostering mental well-being and, in turn, impact conditions like gastric cancer.
However, while these initial findings are promising, we acknowledge the need for further research to fully understand these relationships and the underlying mechanisms involved. The interplay between diet, mental health, and physical health, such as cancer risks, is complex and warrants deeper exploration.
9.5
Improved mental stability
Most Useful Review
Mental stability! This supplement is absolutely essential. Taking it has virtually eliminated my vague anxiety. After discovering my deficiency in vitamin B6, I've been using it regularly. Although I have a panic disorder, I no longer experience anxiety about anticipation or agoraphobia, and my sleep has significantly improved.
Omega 3 Fish Oil
8
Omega-3 improves anxiety in mice
Impact of Omega-3 on Endocannabinoid System Expression and Function, Enhancing Cognition and Behavior in Male Mice.
Most Relevant Research
We explored the impact of an omega-3-rich diet on male mice and found exciting results. Mice that consumed omega-3 showed enhancements in the endocannabinoid system, vital for synaptic function. These dietary changes led to better object recognition and reduced anxiety-like behaviors, as indicated by their time in open arms of an elevated maze.
Though the study demonstrated notable improvements in behavior and cognition, it primarily focused on mice, leaving further research needed to understand omega-3ās effects on human anxiety.
Though the study demonstrated notable improvements in behavior and cognition, it primarily focused on mice, leaving further research needed to understand omega-3ās effects on human anxiety.
8.8
Enhanced confidence
Most Useful Review
This Omega-3 formulation is excellent, providing a high concentration of EPA and DHA with the added benefit of Vitamin D3. It's convenient with just one capsule daily, without any fishy aftertaste. Omega-3s are crucial since theyāre not produced by the body. They boost immunity, alleviate symptoms of depression and anxiety, and strengthen the nervous system. I feel stronger and more secure during the pandemic, and my overall quality of life has improved significantly. Omega-3 should be taken before fat-containing meals for the best results.
Calcium
8
Calcium blockers reduce cocaine withdrawal anxiety
L-type calcium channel blockade attenuates the anxiogenic-like effects of cocaine abstinence in female and male rats.
Most Relevant Research
We explored how blocking L-type calcium channels (LTCCs) could influence anxiety-like behaviors during cocaine abstinence in both female and male rats. In this study, rats were trained to self-administer cocaine or saline, followed by a two-week abstinence period. Throughout this withdrawal phase, we examined their behavior using several tests designed to measure anxiety and mood, notably the elevated plus maze and forced swim test, while also checking for changes in their preference for a sweet solution.
Our findings revealed that cocaine-abstinent rats exhibited increased anxiety, as indicated by reduced time spent in open arms of the maze and heightened immobility in the forced swim test. Administering isradipineāa calcium channel blockerācould reverse some anxiety-like behaviors, with varied efficacy based on sex and dosage. For instance, the lower dose effectively reduced anxiety in female rats, while males required a higher dose to obtain similar results. In terms of immobility during stress tests, both sexes benefited from the lower dose of isradipine, while the higher dose affected both groups regardless of their abstinence condition.
This research emphasizes the potential of LTCCs in managing mood-related symptoms linked to cocaine abstinence, though results suggest a more complex relationship that requires further investigation. Overall, our study presents a hopeful look at calcium channel blockade as a possible avenue for treating anxiety disorders that may arise from substance withdrawal.
Our findings revealed that cocaine-abstinent rats exhibited increased anxiety, as indicated by reduced time spent in open arms of the maze and heightened immobility in the forced swim test. Administering isradipineāa calcium channel blockerācould reverse some anxiety-like behaviors, with varied efficacy based on sex and dosage. For instance, the lower dose effectively reduced anxiety in female rats, while males required a higher dose to obtain similar results. In terms of immobility during stress tests, both sexes benefited from the lower dose of isradipine, while the higher dose affected both groups regardless of their abstinence condition.
This research emphasizes the potential of LTCCs in managing mood-related symptoms linked to cocaine abstinence, though results suggest a more complex relationship that requires further investigation. Overall, our study presents a hopeful look at calcium channel blockade as a possible avenue for treating anxiety disorders that may arise from substance withdrawal.
8.3
Anxiety disappears
Most Useful Review
This complex restores tooth enamel, strengthens nails, and significantly alleviates anxiety while improving sleep and mood. The dosage is convenient!
Folic Acid
7
Folic acid reduces pain, anxiety
Long-term folic acid treatment relieves chronic inflammatory pain and pain-induced anxiety by reducing MMP2 expression in rats.
Most Relevant Research
We examined the effects of long-term folic acid treatment on chronic inflammatory pain and associated anxiety in rats. By injecting adjuvant into the ratsā hindpaw, we created a model to study pain behavior. Our findings showed that folic acid effectively reduced expressions of MMP2, a protein linked to inflammation, resulting in significant pain relief and lowering anxiety levels among the subjects. Overall, this study suggests that folic acid could be a beneficial treatment option for chronic inflammatory pain coupled with anxiety.
9.5
Healthier mood
Most Useful Review
I've been using this vitamin for six months, and it has honestly transformed my life. I can work longer hours and feel healthier overall. Iām not frequently ill now, which is crucial for workplace health. My mood has also vastly improved; I experience no more anxiety!
L Glycine
9.5
Instant relief
Most Useful Review
I find that taking a spoonful helps instantly when I'm feeling depressed or anxious. It really does assist in alleviating both issues effectively.
9.5
Enhances cognitive function
Most Useful Review
Glycine is excellentāit is used to enhance sleep, lessen nervous tension, reduce anxiety, and improve memory and cognitive functions. As a non-essential amino acid, it regulates metabolism, normalises protective processes in the central nervous system, mitigates emotional stress, and boosts mental performance.
Magnesium
7
Magnesium's transient anxiety relief
Probiotics and magnesium orotate for the treatment of major depressive disorder: a randomised double blind controlled trial.
Most Relevant Research
In our quest to understand how magnesium influences anxiety, we conducted a randomized double-blind controlled trial involving 120 adults diagnosed with major depressive disorder (MDD). Participants took either a combination of probiotics, magnesium orotate, and coenzyme Q10 or a placebo for eight weeks.
At the end of the treatment period, we observed that those taking the combination showed significantly lower rates of major depressive episodes compared to those taking the placebo. However, this difference did not persist by the 8-week follow-up. While there was a notable reduction in self-reported symptoms of anxiety and stress during the treatment, this result also lacks long-term significance.
Ultimately, while our findings suggest that magnesium in combination with probiotics and coenzyme Q10 might help alleviate anxiety symptoms for a brief period, the persistent effects are unclear as we found no enduring benefits in the longer term.
At the end of the treatment period, we observed that those taking the combination showed significantly lower rates of major depressive episodes compared to those taking the placebo. However, this difference did not persist by the 8-week follow-up. While there was a notable reduction in self-reported symptoms of anxiety and stress during the treatment, this result also lacks long-term significance.
Ultimately, while our findings suggest that magnesium in combination with probiotics and coenzyme Q10 might help alleviate anxiety symptoms for a brief period, the persistent effects are unclear as we found no enduring benefits in the longer term.
9.5
Calm and balanced
Most Useful Review
I used to experience signs of magnesium deficiency, such as muscle cramps, poor sleep, and anxiety. After consistently taking magnesium for two years, I transformed from a constantly tired and anxious individual into a calm, balanced person. Magnesium has significantly improved my quality of life. I recommend aiming for a daily intake of 300-350 mg, as dietary sources alone are often insufficient.
Sports Fish Oil Omegas
7
Eicosapentaenoic Acid Reduces Anxiety
The Utility of Prolonged Chronic Unpredictable Stress to Study the Effects of Chronic Fluoxetine, Eicosapentaenoic Acid, and Lipopolysaccharide on Anxiety-Like Behavior and Hippocampal Transcriptomic Responses in Male Rats.
Most Relevant Research
We explored the effects of eicosapentaenoic acid (EPA) on anxiety-like behavior in rats exposed to prolonged chronic unpredictable stress (PCUS). Through a 12-week experiment, we assessed how this treatment, along with fluoxetine and lipopolysaccharide, influenced both behavior and gene expression in their brains. The study found that PCUS led to signs of anxiety in the rats, but chronic treatment with EPA significantly corrected these behaviors.
However, while we noted changes in the rats' anxiety responses with EPA, the overall impact on brain gene expression wasn't markedly affected by the treatments. Some specific genes did show changes in expression when treated with fluoxetine, EPA, or their combination, hinting these could be targets for further investigation in stress-related conditions.
In summary, while EPA appears beneficial in reducing anxiety-like behavior, the complexities of its interactions with other treatments require more exploration to fully understand its role in managing anxiety. This study emphasizes the potential for EPA as a therapeutic option, while also inviting further research on its individual and combined effects with other treatments.
However, while we noted changes in the rats' anxiety responses with EPA, the overall impact on brain gene expression wasn't markedly affected by the treatments. Some specific genes did show changes in expression when treated with fluoxetine, EPA, or their combination, hinting these could be targets for further investigation in stress-related conditions.
In summary, while EPA appears beneficial in reducing anxiety-like behavior, the complexities of its interactions with other treatments require more exploration to fully understand its role in managing anxiety. This study emphasizes the potential for EPA as a therapeutic option, while also inviting further research on its individual and combined effects with other treatments.
9.5
Stable mood achieved
Most Useful Review
Excellent! I started taking these to alleviate my anxiety and depression after years of being vegan and lacking omega-3s. I appreciate the quality of this product compared to others. After taking them for a while, my mood stabilised significantly; I really enjoy them!
B1
7
Cessation reduces stigma and anxiety
Quitting smoking after a cancer diagnosis is associated with reductions in stigma and anxiety: A longitudinal mediation analysis.
Most Relevant Research
Our analysis explored how quitting smoking after a cancer diagnosis affects internalized stigma and anxiety. We found that cancer patients who successfully quit smoking reported significant reductions in cancer-related stigma.
These decreases in stigma were also linked to reductions in anxiety over time. However, quitting smoking did not have a notable effect on depressive symptoms. Budding evidence suggests that smoking cessation not only aids in medical outcomes but also enhances the emotional well-being of cancer patients.
These decreases in stigma were also linked to reductions in anxiety over time. However, quitting smoking did not have a notable effect on depressive symptoms. Budding evidence suggests that smoking cessation not only aids in medical outcomes but also enhances the emotional well-being of cancer patients.
8.8
Easier sleep benefits
Most Useful Review
The benefits of vitamin B1 are enormous. On my doctor's advice, I took it for two months and experienced remarkable improvements: easier sleep, reduced irritability, tearfulness, and feelings of anxiety; I felt much warmer.
Iron
7
Iron boosts mental health in pregnancy
Associations between iron status and psychosocial wellbeing among pregnant women in Cape Coast, Ghana: a longitudinal study.
Most Relevant Research
We examined how changes in iron levels during pregnancy relate to anxiety and overall wellbeing. The study followed pregnant women in Cape Coast, Ghana, tracking their iron status and psychological health throughout the first, second, and third trimesters.
Our findings indicate that improvements in iron levels from the first to the second trimester significantly reduced anxiety, especially concerning fearful feelings. The numbers showed that women who enjoyed better iron status experienced less anxiety, which suggests iron supplementation might play a helpful role in enhancing mental health during early pregnancy.
However, we also noted that as iron levels changed from the second to the third trimester, there was a surprising rise in anxiety. Despite initial improvements, some aspects of quality of life declined, indicating the complex relationship between iron status and mental wellbeing.
Overall, this study sheds light on the importance of monitoring and managing iron levels in expecting mothers, as it may impact not only physical health but also emotional wellbeing.
Our findings indicate that improvements in iron levels from the first to the second trimester significantly reduced anxiety, especially concerning fearful feelings. The numbers showed that women who enjoyed better iron status experienced less anxiety, which suggests iron supplementation might play a helpful role in enhancing mental health during early pregnancy.
However, we also noted that as iron levels changed from the second to the third trimester, there was a surprising rise in anxiety. Despite initial improvements, some aspects of quality of life declined, indicating the complex relationship between iron status and mental wellbeing.
Overall, this study sheds light on the importance of monitoring and managing iron levels in expecting mothers, as it may impact not only physical health but also emotional wellbeing.
9.5
Reduced anxiety symptoms
Most Useful Review
I'm pleased with my new hair! I experienced hair loss due to iron deficiency, which is why I chose this supplement, as it has a commendable composition. The capsules are easy to swallow with water. I took one capsule daily for three months, and the packaging was idealāshould I need iron again, I can resume immediately without delay. After six months, I noticed significant growth of small new hairs. Additionally, I struggled with fatigue, which I attributed to depression and anxiety. After the iron course, those issues resolved. I also took iron with vitamin C from NOW Foods. The photo shows my hair's growth, which continues to flourish and resembles bangs now! š
Melatonin
7
Melatonin alleviates prenatal anxiety effects
Prenatal Constant Light Exposure Induces Behavioral Deficits in Male and Female Rat Offspring: Effects of Prenatal Melatonin Treatment.
Most Relevant Research
We explored the impact of prenatal constant light exposure (CLE) and melatonin treatment on anxiety-related behaviors in male and female rat offspring. In our study, six groups of rats were examined, with some experiencing a standard light/dark cycle while others were subjected to CLE. We treated these groups with either a saline solution or melatonin.
Through various anxiety assessments like the open field test and elevated plus maze, we observed that exposure to CLE led to significant behavioral deficits. Specifically, the rats showed heightened anxiety levels, alongside increased plasma cortisol levels. Surprisingly, melatonin treatment repaired these behavioral issues in a way that was different between sexes.
Even though melatonin did not change overall levels of melatonin in the bloodstream or normalize cortisol levels, it did boost the expression of specific brain receptors associated with mood regulation. This suggests that melatonin may hold therapeutic potential for addressing anxiety issues triggered by environmental factors experienced during prenatal development.
Through various anxiety assessments like the open field test and elevated plus maze, we observed that exposure to CLE led to significant behavioral deficits. Specifically, the rats showed heightened anxiety levels, alongside increased plasma cortisol levels. Surprisingly, melatonin treatment repaired these behavioral issues in a way that was different between sexes.
Even though melatonin did not change overall levels of melatonin in the bloodstream or normalize cortisol levels, it did boost the expression of specific brain receptors associated with mood regulation. This suggests that melatonin may hold therapeutic potential for addressing anxiety issues triggered by environmental factors experienced during prenatal development.
9.5
Deep, restful sleep
Most Useful Review
This drug was my salvation. I always suffered from anxiety, which would keep me awake for 2-3 hours. I often woke up in the middle of the night with a racing heartbeat. Taking one pill before bed works wonders; after about 20-25 minutes, I fall asleep peacefully. The sleep is very deep and enjoyable, with calm and colourful dreams. For the first time, I sleep 7-8 hours without disturbance and wake up feeling rested and ready to start my day. My overall condition has improved without any lethargy or weakness.
Childrens Sleep Aids
7
Melatonin alleviates prenatal anxiety effects
Prenatal Constant Light Exposure Induces Behavioral Deficits in Male and Female Rat Offspring: Effects of Prenatal Melatonin Treatment.
Most Relevant Research
We explored the impact of prenatal constant light exposure (CLE) and melatonin treatment on anxiety-related behaviors in male and female rat offspring. In our study, six groups of rats were examined, with some experiencing a standard light/dark cycle while others were subjected to CLE. We treated these groups with either a saline solution or melatonin.
Through various anxiety assessments like the open field test and elevated plus maze, we observed that exposure to CLE led to significant behavioral deficits. Specifically, the rats showed heightened anxiety levels, alongside increased plasma cortisol levels. Surprisingly, melatonin treatment repaired these behavioral issues in a way that was different between sexes.
Even though melatonin did not change overall levels of melatonin in the bloodstream or normalize cortisol levels, it did boost the expression of specific brain receptors associated with mood regulation. This suggests that melatonin may hold therapeutic potential for addressing anxiety issues triggered by environmental factors experienced during prenatal development.
Through various anxiety assessments like the open field test and elevated plus maze, we observed that exposure to CLE led to significant behavioral deficits. Specifically, the rats showed heightened anxiety levels, alongside increased plasma cortisol levels. Surprisingly, melatonin treatment repaired these behavioral issues in a way that was different between sexes.
Even though melatonin did not change overall levels of melatonin in the bloodstream or normalize cortisol levels, it did boost the expression of specific brain receptors associated with mood regulation. This suggests that melatonin may hold therapeutic potential for addressing anxiety issues triggered by environmental factors experienced during prenatal development.
9.5
Children's sleep improved
Most Useful Review
Melatonin has been a sanity saviour! As a foster parent, Iāve seen how it helps anxious children sleep. Despite being tired and calm, they would often lie awake. With a good sleep routine and these gummies, they found the rest they needed, even waking occasionally. The positive changes in the children are remarkable.
L Glutathione
8
Silibinin and naringenin reduce anxiety
Anxiolytic effects of silibinin and naringenin on zebrafish model: A preclinical study.
Most Relevant Research
Our study aimed to determine whether silibinin and naringenin, two flavonoids, could reduce anxiety caused by acute stress using a zebrafish model.
We assessed their effects through behavioral tests, noting that the treated zebrafish showed increased exploration in the upper and well-lit areas of their tanks compared to the control group.
The results suggest that these flavonoids may have potential as therapeutic agents for anxiety with their significant anxiolytic properties.
We assessed their effects through behavioral tests, noting that the treated zebrafish showed increased exploration in the upper and well-lit areas of their tanks compared to the control group.
The results suggest that these flavonoids may have potential as therapeutic agents for anxiety with their significant anxiolytic properties.
9.5
Reduced anxiety symptoms
Most Useful Review
This DIM product combined with vitex is incredible for premenstrual syndrome. Just 13 days into this cycle, I've observed a marked decrease in mood swings and anxiety. I take 2 DIM capsules and 3 VITEX capsules, plus glutathione to detox my kidneys and eliminate hormones. IT HAS CHANGED MY LIFE.
Glucosamine Chondroitin Formulas
7
MSM reduces anxiety in pregnancy
Effectiveness of the mom supports mom peer support intervention in treating antenatal mental health difficulties in women.
Most Relevant Research
We tested a phone-based peer support program called Mom Supports Mom (MSM) to see how it affects anxiety in pregnant women at risk of mental health issues. A total of 167 women participated in the study and were split into two groups. One group received the MSM intervention, while the other group continued with standard care, which didnāt include psychological support.
After one month, we checked in again on the womenās mental health using various assessment tools. While we found that levels of anxiety significantly dropped in the women who engaged in the MSM program, their depressive symptoms remained unchanged. Specifically, the anxiety levels showed a notable reduction, which suggests that the MSM support could help alleviate some of the stress and anxiety faced during pregnancy.
Additionally, we observed an increase in prenatal attachment among the women who received the peer support. This suggests that while MSM helps reduce anxiety, it may not address depression directly. Overall, the findings show promise for using peer support to aid mental well-being during pregnancy, though depression remains a challenge that needs further attention.
After one month, we checked in again on the womenās mental health using various assessment tools. While we found that levels of anxiety significantly dropped in the women who engaged in the MSM program, their depressive symptoms remained unchanged. Specifically, the anxiety levels showed a notable reduction, which suggests that the MSM support could help alleviate some of the stress and anxiety faced during pregnancy.
Additionally, we observed an increase in prenatal attachment among the women who received the peer support. This suggests that while MSM helps reduce anxiety, it may not address depression directly. Overall, the findings show promise for using peer support to aid mental well-being during pregnancy, though depression remains a challenge that needs further attention.
9.5
Manages joint pain
Most Useful Review
These miraculous vitamins, Iām not hesitant to call them that! After about a week of taking them, my knee pain decreased significantly, and my anxiety vanished entirely! I also bought them for my parents, whose joint pain from COVID improved remarkably, along with their anxiety.
B12
7
Vitamin B improves anxiety-related behaviors
[Effects of Vitamin B on Behaviors, Brain Monoamine Neurotransmitters, and Brain-Derived Neurotrophic Factor in Depressive Rats].
Most Relevant Research
We set out to understand how Vitamin B affects behavior and brain chemistry in rats experiencing depression due to stress. In our study, 72 rats were divided into three groups: a control group, a group under stress, and a group under stress receiving Vitamin B injections.
Results showed that Vitamin B helped elevate brain chemicals associated with mood and reduced anxiety-like behaviors by improving neurochemical balance. This suggests a beneficial impact of Vitamin B on anxiety, particularly through its influence on essential neurotransmitters and the brain's supporting structures.
Results showed that Vitamin B helped elevate brain chemicals associated with mood and reduced anxiety-like behaviors by improving neurochemical balance. This suggests a beneficial impact of Vitamin B on anxiety, particularly through its influence on essential neurotransmitters and the brain's supporting structures.
9.5
Anxiety improvements
Most Useful Review
This is my repeat order. It is highly absorbable with no chemical ingredients. I've been taking it for my chronic anxiety and depression, and after three months, my neurological symptoms have greatly improved.
Inositol
7
Myo-Inositol improves anxiety behavior
Assessment of Long-Term Safety and Efficacy of Purple Sweet Potato Color (PSPC) and Myo-Inositol (MI) Treatment for Motor Related and Behavioral Phenotypes in a Mouse Model of Classic Galactosemia.
Most Relevant Research
We aimed to explore the impact of myo-inositol (MI) on anxiety in a mouse model of classic galactosemia. Our research involved a combination of acute and chronic evaluations of MI, particularly looking at its effects over a long-term treatment period. We observed that lower doses of MI suggested notable improvements in motor deficits and anxiety-driven hyperactivity among the GalT-KO mice, which are affected by this condition.
While we conducted a thorough assessment of motor-related behaviors and anxiety levels, it appears that MI holds potential as an adjunct treatment option. These findings indicate that MI may benefit not only physical symptoms but also emotional well-being, particularly in reducing anxiety-related behaviors in this genetically modified model, which helps us understand its role more clearly. The results could point to new avenues for managing anxiety, especially in conditions like classic galactosemia where traditional treatment methods fall short.
While we conducted a thorough assessment of motor-related behaviors and anxiety levels, it appears that MI holds potential as an adjunct treatment option. These findings indicate that MI may benefit not only physical symptoms but also emotional well-being, particularly in reducing anxiety-related behaviors in this genetically modified model, which helps us understand its role more clearly. The results could point to new avenues for managing anxiety, especially in conditions like classic galactosemia where traditional treatment methods fall short.
9.5
Stress reduction
Most Useful Review
These supplements effectively support the nervous system and reduce anxiety. My doctor recommended them, and I've noticed a significant decrease in stress, along with improved liver function. The quality is excellent, and I plan to continue taking them.
B3 Niacin
8
Niacin helps reduce anxiety symptoms
Antioxidant and neuro-modulatory effects of niacin prevent D-galactose-induced behavioral deficits and memory impairment.
Most Relevant Research
We evaluated the impact of niacin on anxiety and memory loss by examining its effects in male rats exposed to D-galactose, a chemical known to induce behavioral deficits. In our study, we divided the animals into six groups, with some receiving niacin at different doses (25 mg/kg and 50 mg/kg) and others being treated with D-galactose.
Over a two-week period, we observed how niacin influenced their behavior in various tests designed to measure anxiety and depression. After administering niacin, we found that it significantly reduced the anxiety and depressive symptoms that had developed due to D-galactose. This was particularly encouraging as niacin also appeared to support memory function in the rats, showing promise for addressing cognitive decline.
Biochemically, niacin treatment helped restore levels of antioxidant enzymes and neurotransmitters affected by D-galactose, demonstrating its potential to combat oxidative stress and inflammation. Our findings suggest that niacin can act as both an antioxidant and a neuromodulator, offering a valuable approach for treating anxiety and associated cognitive impairments in aging.
Over a two-week period, we observed how niacin influenced their behavior in various tests designed to measure anxiety and depression. After administering niacin, we found that it significantly reduced the anxiety and depressive symptoms that had developed due to D-galactose. This was particularly encouraging as niacin also appeared to support memory function in the rats, showing promise for addressing cognitive decline.
Biochemically, niacin treatment helped restore levels of antioxidant enzymes and neurotransmitters affected by D-galactose, demonstrating its potential to combat oxidative stress and inflammation. Our findings suggest that niacin can act as both an antioxidant and a neuromodulator, offering a valuable approach for treating anxiety and associated cognitive impairments in aging.
9.5
Decreased anxiety
Most Useful Review
I purchased this for a teenager with anxiety. Initially, I was on medication, but I tried niacinamide to reduce my dosage. After three months, I started taking 100mg of niacin, two tablets after meals. Iāve adapted to it, and my anxiety has significantly decreased, allowing me to stop my hospital medication. The niacin seems to work well; Iāll soon try niacin 500mg for future prevention. Iām smiling more and feeling brighter, all without side effects, so Iāll keep using it.