Lactobacillus plantarum shows promiseImmune responses of mice inoculated with recombinant Lactobacillus plantarum NC8 expressing the fusion gene HA2 and 3M2e of the influenza virus and protection against different subtypes of influenza virus.
We investigated whether a special strain of Lactobacillus plantarum, modified to express flu virus components, could help protect against bird flu in mice.
Our findings revealed that this treatment significantly boosted immune responses, notably increasing specific antibodies.
Mice vaccinated with the recombinant strains showed notable protection levels against H9N2 and H1N1 viruses, demonstrating up to 80% and 60% protection, respectively.
Overall, these results suggest that recombinant Lactobacillus plantarum could be a promising candidate for oral flu vaccines.
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Lactobacillus improves flu resistanceLactobacillus paracasei feeding improves immune control of influenza infection in mice.
We examined how feeding mice the probiotic Lactobacillus paracasei might enhance their immune response to the flu. This study revealed that after seven days of Lactobacillus intake, mice showed improved lung health and faster recovery from influenza.
These mice experienced less lung inflammation and had a better ability to clear the virus. Though the gut microbiota didn't significantly change in composition, some beneficial strains increased after flu infection.
Overall, this research indicates that Lactobacillus paracasei could play a helpful role in managing flu symptoms and strengthening immunity.
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Lactobacillus boosts immunity against fluHeat-killed Lactobacillus gasseri TMC0356 protects mice against influenza virus infection by stimulating gut and respiratory immune responses.
We explored the impact of heat-killed Lactobacillus gasseri TMC0356 on flu infection in mice. The study showed that mice receiving this treatment had significantly reduced clinical symptoms and lower viral loads compared to controls.
Immune responses, particularly in gut and respiratory areas, were stimulated, leading to increased activity of key immune molecules.
Overall, this suggests that heat-killed lactobacilli could be an effective way to enhance immunity against influenza.
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Lactobacillus shows flu protectionOral administration of lactobacilli from human intestinal tract protects mice against influenza virus infection.
We examined whether oral probiotics, specifically Lactobacillus rhamnosus GG and Lactobacillus gasseri TMC0356, could help protect against influenza in mice.
Over 19 days, these mouse subjects received the probiotics before being infected with the flu virus. Our results revealed that the mice given these lactobacilli showed significantly improved clinical symptoms and lower virus levels in their lungs compared to the control group.
Thus, it appears that these probiotics may offer some level of protection against flu infections through their beneficial interaction with gut immunity.
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Probiotics show mixed benefitsProbiotics for preventing acute upper respiratory tract infections.
We examined whether probiotics, like Lactobacillus, can help prevent flu and other upper respiratory infections. Our analysis included 23 trials with nearly 7,000 participants of all ages.
Results suggest that probiotics may reduce the chances of getting respiratory infections, lower the number of severe cases, and potentially shorten the duration of illness. They might even decrease the need for antibiotics. However, the benefits may not be as strong as initially thought, and we found that adverse effects were minimal.
Overall, while promising, the evidence is mixed, and more research is needed to fully understand how effective probiotics are against the flu.
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