Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Good
Based on 2 Reviews
8.7
Supplement Facts
Serving Size: One (1) Tablet
Amount Per Serving
%DV
Calories
0
Total Carbohydrate
<1 g
<1%+
Total Sugars
0 g
**
Incl. 0 g Added Sugars
0%+
Xylitol
<1 g
**
Lactobacillus rhamnosus GG
53 mg (10 billion CFUs)
**
Top Medical Research Studies
9
Lactobacillus improves infant reflux symptoms
We explored the impact of Lactobacillus reuteri NCIMB 30351 on common gastrointestinal issues in infants, focusing on gastroesophageal reflux. Conducted as a randomized and placebo-controlled trial, 90 infants received either the probiotic drops or a placebo for 25 days.
Our findings revealed that the probiotic significantly reduced regurgitation and crying times while increasing bowel movements in infants with constipation. However, it didn't show strong effects on diarrhea. Overall, Lactobacillus reuteri appears to be a safe and effective option for managing reflux and colic in newborns.
Our findings revealed that the probiotic significantly reduced regurgitation and crying times while increasing bowel movements in infants with constipation. However, it didn't show strong effects on diarrhea. Overall, Lactobacillus reuteri appears to be a safe and effective option for managing reflux and colic in newborns.
Read More
8
Lactobacillus reduces heartburn symptoms
We investigated the impact of heat-killed Lactobacillus No. 1088 on gastroesophageal reflux symptoms in healthy volunteers. In a carefully designed study, 120 participants were randomly assigned to either the Lactobacillus group or placebo for six weeks.
We observed that those taking Lactobacillus experienced significant improvement in heartburn symptoms compared to the placebo group. Overall, it seems that this lactobacillus strain could offer some relief for occasional heartburn in healthy individuals without severe side effects.
We observed that those taking Lactobacillus experienced significant improvement in heartburn symptoms compared to the placebo group. Overall, it seems that this lactobacillus strain could offer some relief for occasional heartburn in healthy individuals without severe side effects.
Read More
8
Lactobacillus reduces gastrointestinal disorders
We investigated whether giving Lactobacillus reuteri DSM 17938 to newborns in their first three months could help prevent infantile colic, reflux, and constipation. In a well-designed study across nine hospitals in Italy, 589 infants received either the probiotic or a placebo.
Parents documented various health and feeding issues in a diary. The results showed that this probiotic did cut down on daily crying times, regurgitation, and constipation, benefiting both families and healthcare costs.
Parents documented various health and feeding issues in a diary. The results showed that this probiotic did cut down on daily crying times, regurgitation, and constipation, benefiting both families and healthcare costs.
Read More
Most Useful Reviews
10
Cured severe reflux
This product practically cured my GERD. I've suffered for years with awful reflux issues, difficulty swallowing, and frequent throat clearing. Taking this once daily has significantly improved my life. I would definitely recommend it to anyone who experiences similar issues.
Read More
9.5
Helps with reflux
It works! It seems to assist with everything it claims, and I'm particularly pleased that it has helped my acid reflux!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
- All Researches
9
Lactobacillus improves infant reflux symptoms
We explored the impact of Lactobacillus reuteri NCIMB 30351 on common gastrointestinal issues in infants, focusing on gastroesophageal reflux. Conducted as a randomized and placebo-controlled trial, 90 infants received either the probiotic drops or a placebo for 25 days.
Our findings revealed that the probiotic significantly reduced regurgitation and crying times while increasing bowel movements in infants with constipation. However, it didn't show strong effects on diarrhea. Overall, Lactobacillus reuteri appears to be a safe and effective option for managing reflux and colic in newborns.
Our findings revealed that the probiotic significantly reduced regurgitation and crying times while increasing bowel movements in infants with constipation. However, it didn't show strong effects on diarrhea. Overall, Lactobacillus reuteri appears to be a safe and effective option for managing reflux and colic in newborns.
Read More
9
This double-blind, randomized controlled trial explored the use of a specialized infant formula with Lactobacillus reuteri DSM 17938 to reduce functional regurgitation (FR) in infants. We found that infants consuming the test formula experienced a significant decrease in regurgitation frequency—from an average of 7.4 to 2.6 regurgitations per day—compared to smaller changes in the control group. Additionally, gastric emptying improved more in the test group, suggesting this combination could offer benefits for managing FR in infants.
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8
Probiotic supplement reduces GERD symptoms
We explored the effects of a dietary supplement containing probiotics, bioactive peptides, and vitamins on heartburn and quality of life in individuals with mild-to-moderate gastroesophageal reflux disease (GERD). In a well-structured, randomized, double-blind, placebo-controlled study involving 56 adults over 28 days, we noted a significant reduction in heartburn frequency and severity in those taking the supplement compared to the placebo group.
Participants also reported taking fewer over-the-counter medications and recognized improvements in their overall quality of life.
Participants also reported taking fewer over-the-counter medications and recognized improvements in their overall quality of life.
Read More
8
Lactobacillus reduces heartburn symptoms
We investigated the impact of heat-killed Lactobacillus No. 1088 on gastroesophageal reflux symptoms in healthy volunteers. In a carefully designed study, 120 participants were randomly assigned to either the Lactobacillus group or placebo for six weeks.
We observed that those taking Lactobacillus experienced significant improvement in heartburn symptoms compared to the placebo group. Overall, it seems that this lactobacillus strain could offer some relief for occasional heartburn in healthy individuals without severe side effects.
We observed that those taking Lactobacillus experienced significant improvement in heartburn symptoms compared to the placebo group. Overall, it seems that this lactobacillus strain could offer some relief for occasional heartburn in healthy individuals without severe side effects.
Read More
8
We explored how a fermented soy product called GAD, made with Lactobacillus delbrueckii, impacts gastroesophageal reflux and peptic ulcers. Using advanced techniques like H NMR spectroscopy, we identified changes in the compounds released during fermentation, including anti-inflammatory molecules.
These changes point to how GAD might reduce inflammation in the stomach, potentially linking its effects to symptom improvement. However, while we noted significant changes in the metabolite profile, further research is necessary to fully assess GAD's effectiveness in managing reflux symptoms.
These changes point to how GAD might reduce inflammation in the stomach, potentially linking its effects to symptom improvement. However, while we noted significant changes in the metabolite profile, further research is necessary to fully assess GAD's effectiveness in managing reflux symptoms.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
10
Cured severe reflux
This product practically cured my GERD. I've suffered for years with awful reflux issues, difficulty swallowing, and frequent throat clearing. Taking this once daily has significantly improved my life. I would definitely recommend it to anyone who experiences similar issues.
Read More
9.5
Helps with reflux
It works! It seems to assist with everything it claims, and I'm particularly pleased that it has helped my acid reflux!
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Tursi F, Benedetto E, Spina A, De Ponti I, Amone F, et al. Efficacy of a Food Supplement Containing LA14, Peptides, and a Multivitamin Complex in Improving Gastroesophageal Reflux Disease-Related Outcomes and Quality of Life of Subjects Showing Mild-to-Moderate Gastroesophageal Reflux Disease. Nutrients. 2024;16. doi:10.3390/nu16111759
- Komatsu Y, Miura H, Iwama Y, Urita Y. Beneficial Effect of Heat-Killed Lactic Acid Bacterium No. 1088 on Temporal Gastroesophageal Reflux-Related Symptoms in Healthy Volunteers: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study. Nutrients. 2024;16. doi:10.3390/nu16081230
- Ethier R, Krishnamurthy A, Jeffrey M, Tompkins TA. Profiling of Metabolites in a Fermented Soy Dietary Supplement Reinforces its Role in the Management of Intestinal Inflammation. Mol Nutr Food Res. 2024;68:e2300770. doi:10.1002/mnfr.202300770
- Tyrsin OY, Tyrsin DY, Nemenov DG, Ruzov AS, Odintsova VE, et al. Effect of Lactobacillus reuteri NCIMB 30351 drops on symptoms of infantile functional gastrointestinal disorders and gut microbiota in early infants: Results from a randomized, placebo-controlled clinical trial. Eur J Pediatr. 2024;183:2311. doi:10.1007/s00431-024-05473-y
- Bernard JN, Chinnaiyan V, Almeda J, Catala-Valentin A, Andl CD. sp. Facilitate the Repair of DNA Damage Caused by Bile-Induced Reactive Oxygen Species in Experimental Models of Gastroesophageal Reflux Disease. Antioxidants (Basel). 2023;12. doi:10.3390/antiox12071314
- Fatani A, Vaher K, Rivero-Mendoza D, Alabasi K, Dahl WJ. Fermented soy supplementation improves indicators of quality of life: a randomized, placebo-controlled, double-blind trial in adults experiencing heartburn. BMC Res Notes. 2020;13:364. doi:10.1186/s13104-020-05205-z
- Horvath A, Leber B, Feldbacher N, Steinwender M, Komarova I, et al. The effects of a multispecies synbiotic on microbiome-related side effects of long-term proton pump inhibitor use: A pilot study. Sci Rep. 2020;10:2723. doi:10.1038/s41598-020-59550-x
- Belei O, Olariu L, Dobrescu A, Marcovici T, Marginean O. Is It Useful to Administer Probiotics Together With Proton Pump Inhibitors in Children With Gastroesophageal Reflux?. J Neurogastroenterol Motil. 2018;24:51. doi:10.5056/jnm17059
- Indrio F, Riezzo G, Giordano P, Ficarella M, Miolla MP, et al. Effect of a Partially Hydrolysed Whey Infant Formula Supplemented with Starch and Lactobacillus reuteri DSM 17938 on Regurgitation and Gastric Motility. Nutrients. 2017;9. doi:10.3390/nu9111181
- Suzuki T, Masui A, Nakamura J, Shiozawa H, Aoki J, et al. Yogurt Containing Lactobacillus gasseri Mitigates Aspirin-Induced Small Bowel Injuries: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial. Digestion. 2017;95:49. doi:10.1159/000452361
- Fujiwara Y, Watanabe T, Muraki M, Yamagami H, Tanigawa T, et al. Association between chronic use of proton pump inhibitors and small- intestinal bacterial overgrowth assessed using lactulose hydrogen breath tests. Hepatogastroenterology. 2015;62:268.
- Aiba Y, Nakano Y, Koga Y, Takahashi K, Komatsu Y. A highly acid-resistant novel strain of Lactobacillus johnsonii No. 1088 has antibacterial activity, including that against Helicobacter pylori, and inhibits gastrin-mediated acid production in mice. Microbiologyopen. 2015;4:465. doi:10.1002/mbo3.252
- Compare D, Rocco A, Sgamato C, Coccoli P, Campo SM, et al. Lactobacillus paracasei F19 versus placebo for the prevention of proton pump inhibitor-induced bowel symptoms: a randomized clinical trial. Dig Liver Dis. 2015;47:273. doi:10.1016/j.dld.2015.01.004
- Igarashi M, Nagano J, Tsuda A, Suzuki T, Koike J, et al. Correlation between the Serum Pepsinogen I Level and the Symptom Degree in Proton Pump Inhibitor-Users Administered with a Probiotic. Pharmaceuticals (Basel). 2014;7:754. doi:10.3390/ph7070754
- Garofoli F, Civardi E, Indrio F, Mazzucchelli I, Angelini M, et al. The early administration of Lactobacillus reuteri DSM 17938 controls regurgitation episodes in full-term breastfed infants. Int J Food Sci Nutr. 2014;65:646. doi:10.3109/09637486.2014.898251
- Indrio F, Di Mauro A, Riezzo G, Civardi E, Intini C, et al. Prophylactic use of a probiotic in the prevention of colic, regurgitation, and functional constipation: a randomized clinical trial. JAMA Pediatr. 2014;168:228. doi:10.1001/jamapediatrics.2013.4367
