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Our findings revealed that the probiotic significantly reduced regurgitation and crying times while increasing bowel movements in infants with constipation. However, it didn't show strong effects on diarrhea. Overall, Lactobacillus reuteri appears to be a safe and effective option for managing reflux and colic in newborns.
We observed that those taking Lactobacillus experienced significant improvement in heartburn symptoms compared to the placebo group. Overall, it seems that this lactobacillus strain could offer some relief for occasional heartburn in healthy individuals without severe side effects.
Parents documented various health and feeding issues in a diary. The results showed that this probiotic did cut down on daily crying times, regurgitation, and constipation, benefiting both families and healthcare costs.
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Our findings revealed that the probiotic significantly reduced regurgitation and crying times while increasing bowel movements in infants with constipation. However, it didn't show strong effects on diarrhea. Overall, Lactobacillus reuteri appears to be a safe and effective option for managing reflux and colic in newborns.
Participants also reported taking fewer over-the-counter medications and recognized improvements in their overall quality of life.
We observed that those taking Lactobacillus experienced significant improvement in heartburn symptoms compared to the placebo group. Overall, it seems that this lactobacillus strain could offer some relief for occasional heartburn in healthy individuals without severe side effects.
These changes point to how GAD might reduce inflammation in the stomach, potentially linking its effects to symptom improvement. However, while we noted significant changes in the metabolite profile, further research is necessary to fully assess GAD's effectiveness in managing reflux symptoms.
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Frequently Asked Questions
Reflux, medically known as gastroesophageal reflux disease (GERD), occurs when stomach acid flows back into the esophagus, the tube that connects the throat to the stomach. This backflow can lead to symptoms such as heartburn, regurgitation, and difficulty swallowing. Reflux can affect people of all ages and may be triggered or worsened by factors such as diet, obesity, smoking, and certain medications. While occasional reflux is common and often manageable with lifestyle changes, chronic reflux can lead to more serious complications if not properly treated.
Managing reflux typically involves a combination of lifestyle modifications—such as avoiding trigger foods, eating smaller meals, and maintaining a healthy weight—and, in some cases, medication to reduce stomach acid production. In more severe cases, surgical options may be considered. If you suspect you have reflux or experience frequent symptoms, it’s advisable to consult a healthcare professional for an accurate diagnosis and personalized treatment plan.
Lactobacillus is a genus of bacteria that plays a crucial role in the fermentation of various foods and is found naturally in the human gut. Known for their probiotic properties, strains of Lactobacillus are commonly utilized in the production of yogurt, sauerkraut, and other fermented products. They are characterized by their rod-shaped structure and ability to convert sugars into lactic acid, which not only helps preserve food but also contributes to the tangy flavor of fermented foods.
In addition to their culinary uses, Lactobacillus bacteria can offer several health benefits. They are known to support gut health by enhancing the balance of beneficial bacteria in the microbiome, potentially aiding in digestion and alleviating symptoms of issues like irritable bowel syndrome (IBS). Regular consumption of Lactobacillus-containing foods or supplements may also bolster the immune system and improve overall digestive health. With a growing interest in gut health, Lactobacillus remains a key player in both dietary and therapeutic contexts.
Lactobacillus, a type of beneficial probiotic bacteria, may help alleviate some gastrointestinal issues, including reflux or gastroesophageal reflux disease (GERD). While more research is needed to establish a direct link between Lactobacillus and reduced reflux symptoms, some studies suggest that probiotics can support overall gut health and improve function of the digestive system. By potentially restoring the balance of gut bacteria and improving digestion, Lactobacillus may help reduce the frequency and severity of reflux episodes.
However, it’s important to note that individual responses to probiotics can vary greatly. Factors such as the specific strain of Lactobacillus, dosage, and a person's unique health profile all play a role in effectiveness. If you're considering using Lactobacillus to help manage reflux, it's advisable to consult with a healthcare provider for personalized guidance. They can help determine if probiotics are a suitable option for you, while also ensuring that any other underlying causes of reflux are appropriately addressed.
Lactobacillus, a beneficial strain of probiotics, is often used to support gut health and may help alleviate symptoms of acid reflux for some individuals. While some users report improvements in their reflux symptoms within a few days to a week, it can take longer, typically around 3 to 4 weeks, for the full effects to manifest. The timeframe can vary greatly depending on factors such as individual metabolism, diet, and the severity of the condition.
It's important to remember that everyone's body responds differently to probiotics, and while some users may see significant changes, others might require more time to notice any difference. Patience is key, and it might also be beneficial to combine probiotics with dietary changes or other lifestyle modifications recommended by healthcare professionals. Remember to consult with your healthcare provider to determine the best approach for your specific situation.
This dietary supplement, containing probiotics such as Lactobacillus, is supported by scientific research as a potential aid for managing reflux symptoms. A study involving adults with gastroesophageal reflux disease (GERD) found that a supplement containing probiotics and other bioactive components led to a significant reduction in heartburn frequency and severity compared to a placebo group ([1]). Additionally, a separate investigation highlighted the promise of Lactobacillus No. 1088 in improving heartburn symptoms among healthy volunteers, further suggesting its potential for occasional reflux relief without serious side effects ([2]).
For infants, the probiotic Lactobacillus reuteri has demonstrated effectiveness in reducing regurgitation and related gastrointestinal issues in controlled studies. Research showed that infants receiving this probiotic experienced a notable decrease in regurgitation frequency, suggesting its viability as a safe management option for reflux ([9]; [16]). These findings indicate that probiotics could play a beneficial role for individuals experiencing reflux, although ongoing studies are needed to establish definitive efficacy and treatment protocols.
Participants also reported taking fewer over-the-counter medications and recognized improvements in their overall quality of life.
We observed that those taking Lactobacillus experienced significant improvement in heartburn symptoms compared to the placebo group. Overall, it seems that this lactobacillus strain could offer some relief for occasional heartburn in healthy individuals without severe side effects.
Parents documented various health and feeding issues in a diary. The results showed that this probiotic did cut down on daily crying times, regurgitation, and constipation, benefiting both families and healthcare costs.
References
- Tursi F, Benedetto E, Spina A, De Ponti I, Amone F, et al. Efficacy of a Food Supplement Containing LA14, Peptides, and a Multivitamin Complex in Improving Gastroesophageal Reflux Disease-Related Outcomes and Quality of Life of Subjects Showing Mild-to-Moderate Gastroesophageal Reflux Disease. Nutrients. 2024;16. doi:10.3390/nu16111759
- Komatsu Y, Miura H, Iwama Y, Urita Y. Beneficial Effect of Heat-Killed Lactic Acid Bacterium No. 1088 on Temporal Gastroesophageal Reflux-Related Symptoms in Healthy Volunteers: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study. Nutrients. 2024;16. doi:10.3390/nu16081230
- Ethier R, Krishnamurthy A, Jeffrey M, Tompkins TA. Profiling of Metabolites in a Fermented Soy Dietary Supplement Reinforces its Role in the Management of Intestinal Inflammation. Mol Nutr Food Res. 2024;68:e2300770. doi:10.1002/mnfr.202300770
- Tyrsin OY, Tyrsin DY, Nemenov DG, Ruzov AS, Odintsova VE, et al. Effect of Lactobacillus reuteri NCIMB 30351 drops on symptoms of infantile functional gastrointestinal disorders and gut microbiota in early infants: Results from a randomized, placebo-controlled clinical trial. Eur J Pediatr. 2024;183:2311. doi:10.1007/s00431-024-05473-y
- Bernard JN, Chinnaiyan V, Almeda J, Catala-Valentin A, Andl CD. sp. Facilitate the Repair of DNA Damage Caused by Bile-Induced Reactive Oxygen Species in Experimental Models of Gastroesophageal Reflux Disease. Antioxidants (Basel). 2023;12. doi:10.3390/antiox12071314
- Fatani A, Vaher K, Rivero-Mendoza D, Alabasi K, Dahl WJ. Fermented soy supplementation improves indicators of quality of life: a randomized, placebo-controlled, double-blind trial in adults experiencing heartburn. BMC Res Notes. 2020;13:364. doi:10.1186/s13104-020-05205-z
- Horvath A, Leber B, Feldbacher N, Steinwender M, Komarova I, et al. The effects of a multispecies synbiotic on microbiome-related side effects of long-term proton pump inhibitor use: A pilot study. Sci Rep. 2020;10:2723. doi:10.1038/s41598-020-59550-x
- Belei O, Olariu L, Dobrescu A, Marcovici T, Marginean O. Is It Useful to Administer Probiotics Together With Proton Pump Inhibitors in Children With Gastroesophageal Reflux?. J Neurogastroenterol Motil. 2018;24:51. doi:10.5056/jnm17059
- Indrio F, Riezzo G, Giordano P, Ficarella M, Miolla MP, et al. Effect of a Partially Hydrolysed Whey Infant Formula Supplemented with Starch and Lactobacillus reuteri DSM 17938 on Regurgitation and Gastric Motility. Nutrients. 2017;9. doi:10.3390/nu9111181
- Suzuki T, Masui A, Nakamura J, Shiozawa H, Aoki J, et al. Yogurt Containing Lactobacillus gasseri Mitigates Aspirin-Induced Small Bowel Injuries: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial. Digestion. 2017;95:49. doi:10.1159/000452361
- Fujiwara Y, Watanabe T, Muraki M, Yamagami H, Tanigawa T, et al. Association between chronic use of proton pump inhibitors and small- intestinal bacterial overgrowth assessed using lactulose hydrogen breath tests. Hepatogastroenterology. 2015;62:268.
- Aiba Y, Nakano Y, Koga Y, Takahashi K, Komatsu Y. A highly acid-resistant novel strain of Lactobacillus johnsonii No. 1088 has antibacterial activity, including that against Helicobacter pylori, and inhibits gastrin-mediated acid production in mice. Microbiologyopen. 2015;4:465. doi:10.1002/mbo3.252
- Compare D, Rocco A, Sgamato C, Coccoli P, Campo SM, et al. Lactobacillus paracasei F19 versus placebo for the prevention of proton pump inhibitor-induced bowel symptoms: a randomized clinical trial. Dig Liver Dis. 2015;47:273. doi:10.1016/j.dld.2015.01.004
- Igarashi M, Nagano J, Tsuda A, Suzuki T, Koike J, et al. Correlation between the Serum Pepsinogen I Level and the Symptom Degree in Proton Pump Inhibitor-Users Administered with a Probiotic. Pharmaceuticals (Basel). 2014;7:754. doi:10.3390/ph7070754
- Garofoli F, Civardi E, Indrio F, Mazzucchelli I, Angelini M, et al. The early administration of Lactobacillus reuteri DSM 17938 controls regurgitation episodes in full-term breastfed infants. Int J Food Sci Nutr. 2014;65:646. doi:10.3109/09637486.2014.898251
- Indrio F, Di Mauro A, Riezzo G, Civardi E, Intini C, et al. Prophylactic use of a probiotic in the prevention of colic, regurgitation, and functional constipation: a randomized clinical trial. JAMA Pediatr. 2014;168:228. doi:10.1001/jamapediatrics.2013.4367
