Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 35 Researches
8
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.4
Supplement Facts
Serving Size: One (1) Capsule
Amount Per Serving
%DV
Calories
0
Total Carbohydrate
0 g
0%+
Total Sugars
0 g
**
Incl. 0 g Added Sugars
0%+
Lactobacillus rhamnosus GG
40 mg (10 billion CFUs)
**
Inulin (Chicory Root Extract)
200 mg
**
Top Medical Research Studies
9.5
Inulin protects against type 1 diabetes
We explored how inulin, a type of prebiotic fiber, impacts the immune response in the context of type 1 diabetes (T1D) using a specific mouse model. Our findings showed that mice treated with inulin alongside a chemical that induces diabetes, called streptozotocin, did not develop the disease. In fact, these mice had lower blood glucose levels, reduced inflammation in their pancreas, and more balanced insulin levels compared to those not receiving inulin.
The mice that received inulin also demonstrated an interesting change in their gut health, showcasing an increase in beneficial bacteria like Bifidobacterium and Akkermansia muciniphila, as well as higher levels of butyrate, a short-chain fatty acid crucial for gut health. This improved gut microbiota seemed to support regulatory T cells, which play an important role in immune regulation.
Specifically, we noted that inulin helped recruit these regulatory T cells into the pancreas, a site critical for managing the immune response in diabetes. This recruitment depended on a specific pathway involving something known as CCR4. When we looked at mice lacking this CCR4 receptor, the beneficial effects of inulin were significantly reduced, highlighting its importance.
Overall, these findings suggest that inulin could be a promising nutritional strategy for enhancing immune health and potentially protecting against autoimmune conditions like T1D.
The mice that received inulin also demonstrated an interesting change in their gut health, showcasing an increase in beneficial bacteria like Bifidobacterium and Akkermansia muciniphila, as well as higher levels of butyrate, a short-chain fatty acid crucial for gut health. This improved gut microbiota seemed to support regulatory T cells, which play an important role in immune regulation.
Specifically, we noted that inulin helped recruit these regulatory T cells into the pancreas, a site critical for managing the immune response in diabetes. This recruitment depended on a specific pathway involving something known as CCR4. When we looked at mice lacking this CCR4 receptor, the beneficial effects of inulin were significantly reduced, highlighting its importance.
Overall, these findings suggest that inulin could be a promising nutritional strategy for enhancing immune health and potentially protecting against autoimmune conditions like T1D.
Read More
9
We explored the potential of Lactobacillus strain LC-STH-13 in treating systemic lupus erythematosus (SLE), a challenging autoimmune disorder. Using female MRL/lpr mice prone to lupus, we found that LC-STH-13 significantly lowered anti-autoantibodies and optimized the balance of immune cells.
Additionally, it reduced kidney inflammation by targeting the TLR9/NF-κB signaling pathway and improved gut health. These results are promising, suggesting that LC-STH-13 could be a safe and effective treatment avenue for SLE.
Additionally, it reduced kidney inflammation by targeting the TLR9/NF-κB signaling pathway and improved gut health. These results are promising, suggesting that LC-STH-13 could be a safe and effective treatment avenue for SLE.
Read More
9
We aimed to understand whether probiotics could ease inflammation in autoimmune pancreatitis (AIP) by interfacing with innate immunity. We set up a mouse model of AIP and treated these mice with Lactobacillus gasseri. The treatment appeared to significantly reduce pancreatitis symptoms, potentially via TLR7 signaling in immune cells.
This suggests that Lactobacillus could be a valuable tool in managing AIP, as we observed crucial interactions between the gut microbiota and the body's immune response.
This suggests that Lactobacillus could be a valuable tool in managing AIP, as we observed crucial interactions between the gut microbiota and the body's immune response.
Read More
Most Useful Reviews
9
Effective for dysbiosis
3 people found this helpful
Solid five! This probiotic works effectively and is very popular in the USA. When I lived there, I learned about it from a local doctor who prescribed it alongside antibiotics to guard against dysbiosis. I take two capsules between doses, and it keeps my body and intestines in order. Additionally, after using it, I’ve noticed a long-lasting reduction in thrush.
Read More
9
Improved wellbeing
I purchased this probiotic from iHerb and had a wonderful experience. The product is excellent, yielding a noticeable improvement in my health. The quality is remarkable, the price is reasonable, and I appreciated the prompt shipping and great customer service. I'm keen to order more in the future!
Read More
2
Sceptical about effectiveness
2 people found this helpful
Recently, I've marked an increase in interest in probiotics for enhancing the immune system and digestion. Although doctors recommend various options alongside antibiotics, I have reservations about pharmacy drugs. I tried these probiotics after antibiotics but didn’t notice any gastrointestinal discomfort. Unfortunately, they didn’t improve my skin condition either, leading to my lower evaluation.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 35 Researches
8
- All Researches
9.5
Inulin protects against type 1 diabetes
We explored how inulin, a type of prebiotic fiber, impacts the immune response in the context of type 1 diabetes (T1D) using a specific mouse model. Our findings showed that mice treated with inulin alongside a chemical that induces diabetes, called streptozotocin, did not develop the disease. In fact, these mice had lower blood glucose levels, reduced inflammation in their pancreas, and more balanced insulin levels compared to those not receiving inulin.
The mice that received inulin also demonstrated an interesting change in their gut health, showcasing an increase in beneficial bacteria like Bifidobacterium and Akkermansia muciniphila, as well as higher levels of butyrate, a short-chain fatty acid crucial for gut health. This improved gut microbiota seemed to support regulatory T cells, which play an important role in immune regulation.
Specifically, we noted that inulin helped recruit these regulatory T cells into the pancreas, a site critical for managing the immune response in diabetes. This recruitment depended on a specific pathway involving something known as CCR4. When we looked at mice lacking this CCR4 receptor, the beneficial effects of inulin were significantly reduced, highlighting its importance.
Overall, these findings suggest that inulin could be a promising nutritional strategy for enhancing immune health and potentially protecting against autoimmune conditions like T1D.
The mice that received inulin also demonstrated an interesting change in their gut health, showcasing an increase in beneficial bacteria like Bifidobacterium and Akkermansia muciniphila, as well as higher levels of butyrate, a short-chain fatty acid crucial for gut health. This improved gut microbiota seemed to support regulatory T cells, which play an important role in immune regulation.
Specifically, we noted that inulin helped recruit these regulatory T cells into the pancreas, a site critical for managing the immune response in diabetes. This recruitment depended on a specific pathway involving something known as CCR4. When we looked at mice lacking this CCR4 receptor, the beneficial effects of inulin were significantly reduced, highlighting its importance.
Overall, these findings suggest that inulin could be a promising nutritional strategy for enhancing immune health and potentially protecting against autoimmune conditions like T1D.
Read More
9
We examined how probiotics affect immune cells in rheumatoid arthritis (RA) patients. By isolating monocytes from both RA patients and healthy individuals, we created macrophages that were treated with different probiotic bacteria.
Our findings revealed that probiotic treatment shifted macrophages towards a more anti-inflammatory state while reducing markers of inflammation. Notably, probiotics increased levels of beneficial anti-inflammatory substances and decreased harmful inflammatory responses.
This suggests probiotics could play a role in managing RA through their influence on immune cell behavior.
Our findings revealed that probiotic treatment shifted macrophages towards a more anti-inflammatory state while reducing markers of inflammation. Notably, probiotics increased levels of beneficial anti-inflammatory substances and decreased harmful inflammatory responses.
This suggests probiotics could play a role in managing RA through their influence on immune cell behavior.
Read More
9
We explored the potential of Lactobacillus strain LC-STH-13 in treating systemic lupus erythematosus (SLE), a challenging autoimmune disorder. Using female MRL/lpr mice prone to lupus, we found that LC-STH-13 significantly lowered anti-autoantibodies and optimized the balance of immune cells.
Additionally, it reduced kidney inflammation by targeting the TLR9/NF-κB signaling pathway and improved gut health. These results are promising, suggesting that LC-STH-13 could be a safe and effective treatment avenue for SLE.
Additionally, it reduced kidney inflammation by targeting the TLR9/NF-κB signaling pathway and improved gut health. These results are promising, suggesting that LC-STH-13 could be a safe and effective treatment avenue for SLE.
Read More
9
We investigated how diet influences autoimmune diseases, particularly using a ketogenic diet (KD) model. The KD improved conditions in a mouse model of multiple sclerosis by interacting with the gut microbiome.
Notably, lactobacillus variants were linked to reduced immune cell activation. We found that a specific strain, L. murinus, offered protection against autoimmune conditions, demonstrating the potential of lactobacillus combined with diet-dependent compounds to impact immunity positively.
Overall, our findings underscore the importance of dietary factors and gut bacteria in managing autoimmune disorders.
Notably, lactobacillus variants were linked to reduced immune cell activation. We found that a specific strain, L. murinus, offered protection against autoimmune conditions, demonstrating the potential of lactobacillus combined with diet-dependent compounds to impact immunity positively.
Overall, our findings underscore the importance of dietary factors and gut bacteria in managing autoimmune disorders.
Read More
9
We aimed to understand whether probiotics could ease inflammation in autoimmune pancreatitis (AIP) by interfacing with innate immunity. We set up a mouse model of AIP and treated these mice with Lactobacillus gasseri. The treatment appeared to significantly reduce pancreatitis symptoms, potentially via TLR7 signaling in immune cells.
This suggests that Lactobacillus could be a valuable tool in managing AIP, as we observed crucial interactions between the gut microbiota and the body's immune response.
This suggests that Lactobacillus could be a valuable tool in managing AIP, as we observed crucial interactions between the gut microbiota and the body's immune response.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective for dysbiosis
3 people found this helpful
Solid five! This probiotic works effectively and is very popular in the USA. When I lived there, I learned about it from a local doctor who prescribed it alongside antibiotics to guard against dysbiosis. I take two capsules between doses, and it keeps my body and intestines in order. Additionally, after using it, I’ve noticed a long-lasting reduction in thrush.
Read More
9
Improved wellbeing
I purchased this probiotic from iHerb and had a wonderful experience. The product is excellent, yielding a noticeable improvement in my health. The quality is remarkable, the price is reasonable, and I appreciated the prompt shipping and great customer service. I'm keen to order more in the future!
Read More
2
Sceptical about effectiveness
2 people found this helpful
Recently, I've marked an increase in interest in probiotics for enhancing the immune system and digestion. Although doctors recommend various options alongside antibiotics, I have reservations about pharmacy drugs. I tried these probiotics after antibiotics but didn’t notice any gastrointestinal discomfort. Unfortunately, they didn’t improve my skin condition either, leading to my lower evaluation.
Read More
7.5
Relieved digestive issues
1 people found this helpful
A few years ago, a friend from America recommended this probiotic as one of the best. I decided to try it again and ordered it from iHerb. After starting the capsules, my previous intestinal pains disappeared, and I no longer experienced bloating. I now take one capsule at night.
Read More
7.5
Bowel movement support
The inclusion of inulin seems effective for bowel movements, and I noticed a distinct improvement. I used to suffer from indigestion, but the bloating has significantly decreased, and I'm pleased with the results.
Read More
Frequently Asked Questions
7.5
Relieved digestive issues
1 people found this helpful
A few years ago, a friend from America recommended this probiotic as one of the best. I decided to try it again and ordered it from iHerb. After starting the capsules, my previous intestinal pains disappeared, and I no longer experienced bloating. I now take one capsule at night.
4
Limited impact
I acquired this product at a discount but didn’t notice any significant effects. Perhaps a longer usage period is necessary, yet I’ve experienced better probiotics in the past.
2
No noticeable effect
2 people found this helpful
I ordered these probiotics, convinced by their high ratings on a popular American website. However, I did not feel any notable effects after using them.
9
Effective for dysbiosis
3 people found this helpful
Solid five! This probiotic works effectively and is very popular in the USA. When I lived there, I learned about it from a local doctor who prescribed it alongside antibiotics to guard against dysbiosis. I take two capsules between doses, and it keeps my body and intestines in order. Additionally, after using it, I’ve noticed a long-lasting reduction in thrush.
7.5
Bowel movement support
The inclusion of inulin seems effective for bowel movements, and I noticed a distinct improvement. I used to suffer from indigestion, but the bloating has significantly decreased, and I'm pleased with the results.
7.5
Strengthens immunity
1 people found this helpful
This complex of probiotics is highly recommended, especially after antibiotics. It helps in strengthening immunity and restoring balance to the microbiome, which is crucial for health.
2
Sceptical about effectiveness
2 people found this helpful
Recently, I've marked an increase in interest in probiotics for enhancing the immune system and digestion. Although doctors recommend various options alongside antibiotics, I have reservations about pharmacy drugs. I tried these probiotics after antibiotics but didn’t notice any gastrointestinal discomfort. Unfortunately, they didn’t improve my skin condition either, leading to my lower evaluation.
9
We explored the potential of Lactobacillus strain LC-STH-13 in treating systemic lupus erythematosus (SLE), a challenging autoimmune disorder. Using female MRL/lpr mice prone to lupus, we found that LC-STH-13 significantly lowered anti-autoantibodies and optimized the balance of immune cells.
Additionally, it reduced kidney inflammation by targeting the TLR9/NF-κB signaling pathway and improved gut health. These results are promising, suggesting that LC-STH-13 could be a safe and effective treatment avenue for SLE.
Additionally, it reduced kidney inflammation by targeting the TLR9/NF-κB signaling pathway and improved gut health. These results are promising, suggesting that LC-STH-13 could be a safe and effective treatment avenue for SLE.
8
Lactobacillus modifies inflammation in lupus
We investigated the effects of Lactobacillus delbrueckii and Lactobacillus rhamnosus on immune responses in newly diagnosed systemic lupus erythematosus patients. By examining blood-derived macrophages, we observed that these probiotics can decrease key inflammatory markers and promote a healthier balance in macrophage populations. Notably, they lowered certain harmful cytokines while increasing beneficial ones in both lupus patients and healthy individuals. Although the probiotics showed promise in inducing an anti-inflammatory profile, their overall effectiveness in managing SLE aspects needs further exploration.
9
We examined how probiotics affect immune cells in rheumatoid arthritis (RA) patients. By isolating monocytes from both RA patients and healthy individuals, we created macrophages that were treated with different probiotic bacteria.
Our findings revealed that probiotic treatment shifted macrophages towards a more anti-inflammatory state while reducing markers of inflammation. Notably, probiotics increased levels of beneficial anti-inflammatory substances and decreased harmful inflammatory responses.
This suggests probiotics could play a role in managing RA through their influence on immune cell behavior.
Our findings revealed that probiotic treatment shifted macrophages towards a more anti-inflammatory state while reducing markers of inflammation. Notably, probiotics increased levels of beneficial anti-inflammatory substances and decreased harmful inflammatory responses.
This suggests probiotics could play a role in managing RA through their influence on immune cell behavior.
8
Lactobacillus shows promise for therapy
We explored the therapeutic effects of Lactobacillus and Bifidobacterium on a rat model of demyelination, aiming to understand how gut bacteria influence inflammatory disorders like multiple sclerosis.
In our study, we found that supplementing with these lactic acid bacteria greatly improved behavioral deficits and reduced demyelination.
Additionally, the treatments helped lower oxidative stress and enhanced serum levels of vitamins D and B. These promising results suggest that incorporating Lactobacillus may serve as a supportive therapy for conditions like multiple sclerosis.
In our study, we found that supplementing with these lactic acid bacteria greatly improved behavioral deficits and reduced demyelination.
Additionally, the treatments helped lower oxidative stress and enhanced serum levels of vitamins D and B. These promising results suggest that incorporating Lactobacillus may serve as a supportive therapy for conditions like multiple sclerosis.
References
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- Kazemimiraki M, Moazamian E, Mokhtari MJ, Gholamzad M. The Role of Lactic Acid Bacteria in Improving Behavioral Deficits, Serum Levels of Vitamin D3, B12 and Reducing Oxidative Stress and Demyelination in a Cuprizone-induced Demyelination Model of Rat. Neuromolecular Med. 2025;27:14. 10.1007/s12017-025-08837-1
- Qu H, Fu XX, Han S. C16 peptide and angiopoietin-1 alleviate the side effects of glucocorticoids in a rat multiple sclerosis model. Life Sci. 2025;363:123402. 10.1016/j.lfs.2025.123402
- Liao W, Zhang X, Jia C, Chen W, Cai Y, et al. LC-STH-13 ameliorates the progression of SLE in MRL/lpr mice by inhibiting the TLR9/NF-κB signaling pathway. Food Funct. 2025;16:475. 10.1039/d4fo03966a
- Alexander M, Upadhyay V, Rock R, Ramirez L, Trepka K, et al. A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity. Cell Rep. 2024;43:114891. 10.1016/j.celrep.2024.114891
- Mirfeizi Z, Mahmoudi M, Jokar MH, Sahebari M, Noori E, et al. Impact of synbiotics on disease activity in systemic lupus erythematosus: Results from a randomized clinical trial. J Food Sci. 2024;89:9835. 10.1111/1750-3841.17460
- Gangaiah D, Gu M, Zaparte A, Will O, Dolan LC, et al. Effects of Limosilactobacillus reuteri strains PTA-126787 and PTA-126788 on intestinal barrier integrity and immune homeostasis in an alcohol-induced leaky gut model. Sci Rep. 2024;14:19584. 10.1038/s41598-024-70549-6
- Straus Farber R, Walker EL, Diallo F, Onomichi K, Riley C, et al. A randomized cross-over trial of prebiotics and probiotics in multiple sclerosis: Trial feasibility, supplement tolerability and symptom abatement. Mult Scler Relat Disord. 2024;89:105762. 10.1016/j.msard.2024.105762
- Sprenger-Svačina A, Klein I, Svačina MKR, Bobylev I, Kohle F, et al. Antibiotics-Induced Intestinal Immunomodulation Attenuates Experimental Autoimmune Neuritis (EAN). J Neuroimmune Pharmacol. 2024;19:26. 10.1007/s11481-024-10119-9
- Ito S, Higashiyama M, Nishimura H, Tomioka A, Tanemoto R, et al. The Role of Gut Microbiota and Innate Immune Response in an Autoimmune Pancreatitis Model. Pancreas. 2024;53:e617. 10.1097/MPA.0000000000002339
- Javanmardi Z, Mahmoudi M, Rafatpanah H, Rezaieyazdi Z, Shapouri-Moghaddam A, et al. Tolerogenic probiotics Lactobacillus delbrueckii and Lactobacillus rhamnosus promote anti-inflammatory profile of macrophages-derived monocytes of newly diagnosed patients with systemic lupus erythematosus. Cell Biochem Funct. 2024;42:e3981. 10.1002/cbf.3981
- Vahidi Z, Saghi E, Mahmoudi M, RezaieYazdi Z, Esmaeili SA, et al. Lactobacillus rhamnosus and Lactobacillus delbrueckii Ameliorate the Expression of miR-125a and miR-146a in Systemic Lupus Erythematosus Patients. Appl Biochem Biotechnol. 2024;196:6330. 10.1007/s12010-023-04827-w
- Hoseinzadeh A, Mahmoudi M, Rafatpanah H, Rezaieyazdi Z, Tavakol Afshari J, et al. A new generation of mesenchymal stromal/stem cells differentially trained by immunoregulatory probiotics in a lupus microenvironment. Stem Cell Res Ther. 2023;14:358. 10.1186/s13287-023-03578-z
- Tripathy A, Swain N, Padhan P, Raghav SK, Gupta B. Lactobacillus rhamnosus reduces CD8T cell mediated inflammation in patients with rheumatoid arthritis. Immunobiology. 2023;228:152415. 10.1016/j.imbio.2023.152415
- Furone F, Bellomo C, Carpinelli M, Nicoletti M, Hewa-Munasinghege FN, et al. The protective role of GG postbiotic on the alteration of autophagy and inflammation pathways induced by gliadin in intestinal models. Front Med (Lausanne). 2023;10:1085578. 10.3389/fmed.2023.1085578
- Lin H, Lin J, Pan T, Li T, Jiang H, et al. Polymeric immunoglobulin receptor deficiency exacerbates autoimmune hepatitis by inducing intestinal dysbiosis and barrier dysfunction. Cell Death Dis. 2023;14:68. 10.1038/s41419-023-05589-3
- Samani SA, Moloudi MR, Ramezanzadeh R, Abdi M, Nikkhoo B, et al. Oral Administration of Probiotic to Ameliorate Experimental Autoimmune Encephalomyelitis in Mice. Basic Clin Neurosci. 2022;13:35. 10.32598/bcn.2021.1955.1
- Monzani R, Gagliardi M, Clemente N, Saverio V, Pańczyszyn E, et al. The Gut-Ex-Vivo System (GEVS) Is a Dynamic and Versatile Tool for the Study of DNBS-Induced IBD in BALB/C and C57BL/6 Mice, Highlighting the Protective Role of Probiotics. Biology (Basel). 2022;11. 10.3390/biology11111574
- Petersen AØ, Jokinen M, Plichta DR, Liebisch G, Gronwald W, et al. Cytokine-specific autoantibodies shape the gut microbiome in autoimmune polyendocrine syndrome type 1. J Allergy Clin Immunol. 2021;148:876. 10.1016/j.jaci.2021.03.025
- Liu Y, Hoang TK, Taylor CM, Park ES, Freeborn J, et al. and differentially affect gut microbes and metabolites in mice with Treg deficiency. Am J Physiol Gastrointest Liver Physiol. 2021;320:G969. 10.1152/ajpgi.00072.2021
- Fan Z, Yang B, Ross RP, Stanton C, Zhao J, et al. The prophylactic effects of different Lactobacilli on collagen-induced arthritis in rats. Food Funct. 2020;11:3681. 10.1039/c9fo02556a
- Khorasani S, Mahmoudi M, Kalantari MR, Lavi Arab F, Esmaeili SA, et al. Amelioration of regulatory T cells by Lactobacillus delbrueckii and Lactobacillus rhamnosus in pristane-induced lupus mice model. J Cell Physiol. 2019;234:9778. 10.1002/jcp.27663
- Mardani F, Mahmoudi M, Esmaeili SA, Khorasani S, Tabasi N, et al. In vivo study: Th1-Th17 reduction in pristane-induced systemic lupus erythematosus mice after treatment with tolerogenic Lactobacillus probiotics. J Cell Physiol. 2018;234:642. 10.1002/jcp.26819
- Li N, Han X, Ruan M, Huang F, Yang L, et al. Prebiotic inulin controls Th17 cells mediated central nervous system autoimmunity through modulating the gut microbiota and short chain fatty acids. Gut Microbes. 2024;16:2402547. 10.1080/19490976.2024.2402547
- Lou Y, Wen X, Song S, Zeng Y, Huang L, et al. Dietary pectin and inulin: A promising adjuvant supplement for collagen-induced arthritis through gut microbiome restoration and CD4 T cell reconstitution. J Nutr Biochem. 2024;133:109699. 10.1016/j.jnutbio.2024.109699
- Hashmi HF, Xuan X, Chen K, Zhang P, Shahab M, et al. Molecular modeling and simulation approaches to characterize potential molecular targets for burdock inulin to instigate protection against autoimmune diseases. Sci Rep. 2024;14:11291. 10.1038/s41598-024-61387-7
- Moleón J, González-Correa C, Miñano S, Robles-Vera I, de la Visitación N, et al. Protective effect of microbiota-derived short chain fatty acids on vascular dysfunction in mice with systemic lupus erythematosus induced by toll like receptor 7 activation. Pharmacol Res. 2023;198:106997. 10.1016/j.phrs.2023.106997
- Guimarães JB, Rodrigues VF, Pereira ÍS, Manso GMDC, Elias-Oliveira J, et al. Inulin prebiotic ameliorates type 1 diabetes dictating regulatory T cell homing via CCR4 to pancreatic islets and butyrogenic gut microbiota in murine model. J Leukoc Biol. 2024;115:483. 10.1093/jleuko/qiad132
- Moleón J, González-Correa C, Robles-Vera I, Miñano S, de la Visitación N, et al. Targeting the gut microbiota with dietary fibers: a novel approach to prevent the development cardiovascular complications linked to systemic lupus erythematosus in a preclinical study. Gut Microbes. 2023;15:2247053. 10.1080/19490976.2023.2247053
- Lo Conte M, Antonini Cencicchio M, Ulaszewska M, Nobili A, Cosorich I, et al. A diet enriched in omega-3 PUFA and inulin prevents type 1 diabetes by restoring gut barrier integrity and immune homeostasis in NOD mice. Front Immunol. 2022;13:1089987. 10.3389/fimmu.2022.1089987
- Zhang R, Xiao Y, Yan J, Yang W, Wu X, et al. Effects of Berberine Plus Inulin on Diabetes Care in Patients With Latent Autoimmune Diabetes in Adults: Protocol for a Randomized Controlled Trial. Front Endocrinol (Lausanne). 2022;13:876657. 10.3389/fendo.2022.876657
- Zou J, Reddivari L, Shi Z, Li S, Wang Y, et al. Inulin Fermentable Fiber Ameliorates Type I Diabetes via IL22 and Short-Chain Fatty Acids in Experimental Models. Cell Mol Gastroenterol Hepatol. 2021;12:983. 10.1016/j.jcmgh.2021.04.014
- Ho J, Nicolucci AC, Virtanen H, Schick A, Meddings J, et al. Effect of Prebiotic on Microbiota, Intestinal Permeability, and Glycemic Control in Children With Type 1 Diabetes. J Clin Endocrinol Metab. 2019;104:4427. 10.1210/jc.2019-00481
- Chen K, Chen H, Faas MM, de Haan BJ, Li J, et al. Specific inulin-type fructan fibers protect against autoimmune diabetes by modulating gut immunity, barrier function, and microbiota homeostasis. Mol Nutr Food Res. 2017;61. 10.1002/mnfr.201601006
- Sitkin SI, Tkachenko EI, Vakhitov TIa, Oreshko LS, Zhigalova TN. [Serum metabolome by gas chromatography-mass spectrometry (GC-MS) in patients with ulcerative colitis and celiac disease]. Eksp Klin Gastroenterol. 2013.
