Overview
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
5.5
USERS' SCORE
Good
Based on 3 Reviews
8.3
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Coenzyme Q10 (Ubiquinone)
100 mg
†
Black Pepper Ext. (Piper nigrum) (fruit) (standardized to contain 95% Piperine) (BioPerine®)
5 mg
†
Top Medical Research Studies
4
We evaluated the levels of Coenzyme Q10 (CoQ10) in patients with hypothyroidism and hyperthyroidism to understand its role in thyroid health. The study included participants from both groups, as well as a control group without thyroid issues, ensuring that no subjects had other cardiovascular or metabolic diseases that could interfere with the results.
Our findings showed that hypothyroid patients had a higher average level of CoQ10 in their blood compared to those with hyperthyroidism. Specifically, hypothyroid patients showed levels of 0.97 mcg/ml, while hyperthyroid patients had only 0.51 mcg/ml, with the control group at 0.73 mcg/ml. This suggests that patients with hypothyroidism may have a greater prevalence of higher CoQ10 levels.
However, we found that the differences were not enough to clearly separate those with normal thyroid function from those with either hypothyroidism or hyperthyroidism. While there is a noted inverse relationship between CoQ10 levels and certain thyroid hormones, this indicates that CoQ10 alone may not provide significant benefits for those specifically dealing with hypothyroidism. More research—especially longitudinal studies—is needed to see how treatment and therapy could potentially affect CoQ10 levels and overall thyroid health in these patients.
Our findings showed that hypothyroid patients had a higher average level of CoQ10 in their blood compared to those with hyperthyroidism. Specifically, hypothyroid patients showed levels of 0.97 mcg/ml, while hyperthyroid patients had only 0.51 mcg/ml, with the control group at 0.73 mcg/ml. This suggests that patients with hypothyroidism may have a greater prevalence of higher CoQ10 levels.
However, we found that the differences were not enough to clearly separate those with normal thyroid function from those with either hypothyroidism or hyperthyroidism. While there is a noted inverse relationship between CoQ10 levels and certain thyroid hormones, this indicates that CoQ10 alone may not provide significant benefits for those specifically dealing with hypothyroidism. More research—especially longitudinal studies—is needed to see how treatment and therapy could potentially affect CoQ10 levels and overall thyroid health in these patients.
Read More
7
We explored the effects of a combination of magnesium, selenium, and coenzyme Q10 on the thyroid morphology in patients suffering from benign thyroid diseases, specifically looking at both hyperthyroidism and hypothyroidism. Our study involved 8 patients who received standard pharmacological treatment but also underwent additional therapy at our private institution.
Over a period of 2 to 4 years, we observed some remarkable changes. Initially, we addressed musculoskeletal issues and psychological stressors in our patients. Following this, thyroid morphology started to normalize, with improvements visible through ultrasound imaging. Notably, thyroid antibody levels declined in most patients, suggesting a positive response to the treatment.
However, it's essential to highlight that we could not assess the isolated impact of coenzyme Q10 on hypothyroidism specifically, as it was part of a broader treatment regimen. While we saw promising results, we encountered limited success in two cases where chronic thyroiditis had persisted for over ten years, suggesting that factors like fibrosis may influence treatment outcomes.
Overall, despite the small sample size, our findings challenge the idea that thyroid issues are perpetually autoimmune and irreversible, opening up new avenues for therapeutic options for patients with thyroid diseases.
Over a period of 2 to 4 years, we observed some remarkable changes. Initially, we addressed musculoskeletal issues and psychological stressors in our patients. Following this, thyroid morphology started to normalize, with improvements visible through ultrasound imaging. Notably, thyroid antibody levels declined in most patients, suggesting a positive response to the treatment.
However, it's essential to highlight that we could not assess the isolated impact of coenzyme Q10 on hypothyroidism specifically, as it was part of a broader treatment regimen. While we saw promising results, we encountered limited success in two cases where chronic thyroiditis had persisted for over ten years, suggesting that factors like fibrosis may influence treatment outcomes.
Overall, despite the small sample size, our findings challenge the idea that thyroid issues are perpetually autoimmune and irreversible, opening up new avenues for therapeutic options for patients with thyroid diseases.
Read More
7
We explored the relationship between Coenzyme Q10 (CoQ10) levels and thyroid hormones in patients suffering from chronic obstructive pulmonary disease (COPD). Our study involved 15 older adults, aged 69 to 82, and aimed to see how differing levels of free-T3 (FT3)—a thyroid hormone—would affect CoQ10 concentrations.
The results revealed an intriguing trend: patients exhibiting low FT3 levels had significantly higher CoQ10 levels compared to those with normal FT3 levels. Specifically, we found CoQ10 levels of 0.91 µg/ml in the low FT3 group versus 0.7 µg/ml in the normal FT3 group. Even when we normalized these levels with cholesterol, the difference was consistent, suggesting a metabolic aspect of hypothyroidism linked to lower thyroid hormone levels.
While these findings provide insight into how CoQ10 behaves in the context of thyroid hormone variation among COPD patients, they also raise questions about possible treatments. The elevated CoQ10 levels in patients with low FT3 suggest an adaptation mechanism similar to those seen in true hypothyroid states. However, whether CoQ10 supplementation could effectively address hypothyroidism still needs more rigorous study.
The results revealed an intriguing trend: patients exhibiting low FT3 levels had significantly higher CoQ10 levels compared to those with normal FT3 levels. Specifically, we found CoQ10 levels of 0.91 µg/ml in the low FT3 group versus 0.7 µg/ml in the normal FT3 group. Even when we normalized these levels with cholesterol, the difference was consistent, suggesting a metabolic aspect of hypothyroidism linked to lower thyroid hormone levels.
While these findings provide insight into how CoQ10 behaves in the context of thyroid hormone variation among COPD patients, they also raise questions about possible treatments. The elevated CoQ10 levels in patients with low FT3 suggest an adaptation mechanism similar to those seen in true hypothyroid states. However, whether CoQ10 supplementation could effectively address hypothyroidism still needs more rigorous study.
Read More
Most Useful Reviews
9
Supports thyroid recovery
2 people found this helpful
I have bought this product multiple times for heart health. My husband has taken it for over five years, witnessing substantial improvement in his heart condition. I started it this year for my hypothyroidism and hyperlipidemia, and it appears to aid in restoring thyroid function while protecting cardiovascular health.
Read More
7.5
Boosted energy levels
27 people found this helpful
Coenzyme Q10 is a vital compound produced by the liver that aids in energy production. After five days of taking it, I noticed significant improvement in my energy and mood. My productivity increased, and I fell asleep more easily. This supplement is fantastic, particularly for addressing my hypothyroidism.
Read More
7.5
Irreplaceable supplement
This coenzyme is excellent! I take one capsule twice daily with meals; it enhances mitochondrial function, providing more energy and mental clarity. With my hypothyroidism, this supplement is indispensable. I noticed a notable boost in my energy levels and overall cognitive function.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
5.5
- All Researches
7
We explored the effects of a combination of magnesium, selenium, and coenzyme Q10 on the thyroid morphology in patients suffering from benign thyroid diseases, specifically looking at both hyperthyroidism and hypothyroidism. Our study involved 8 patients who received standard pharmacological treatment but also underwent additional therapy at our private institution.
Over a period of 2 to 4 years, we observed some remarkable changes. Initially, we addressed musculoskeletal issues and psychological stressors in our patients. Following this, thyroid morphology started to normalize, with improvements visible through ultrasound imaging. Notably, thyroid antibody levels declined in most patients, suggesting a positive response to the treatment.
However, it's essential to highlight that we could not assess the isolated impact of coenzyme Q10 on hypothyroidism specifically, as it was part of a broader treatment regimen. While we saw promising results, we encountered limited success in two cases where chronic thyroiditis had persisted for over ten years, suggesting that factors like fibrosis may influence treatment outcomes.
Overall, despite the small sample size, our findings challenge the idea that thyroid issues are perpetually autoimmune and irreversible, opening up new avenues for therapeutic options for patients with thyroid diseases.
Over a period of 2 to 4 years, we observed some remarkable changes. Initially, we addressed musculoskeletal issues and psychological stressors in our patients. Following this, thyroid morphology started to normalize, with improvements visible through ultrasound imaging. Notably, thyroid antibody levels declined in most patients, suggesting a positive response to the treatment.
However, it's essential to highlight that we could not assess the isolated impact of coenzyme Q10 on hypothyroidism specifically, as it was part of a broader treatment regimen. While we saw promising results, we encountered limited success in two cases where chronic thyroiditis had persisted for over ten years, suggesting that factors like fibrosis may influence treatment outcomes.
Overall, despite the small sample size, our findings challenge the idea that thyroid issues are perpetually autoimmune and irreversible, opening up new avenues for therapeutic options for patients with thyroid diseases.
Read More
7
We explored the relationship between Coenzyme Q10 (CoQ10) levels and thyroid hormones in patients suffering from chronic obstructive pulmonary disease (COPD). Our study involved 15 older adults, aged 69 to 82, and aimed to see how differing levels of free-T3 (FT3)—a thyroid hormone—would affect CoQ10 concentrations.
The results revealed an intriguing trend: patients exhibiting low FT3 levels had significantly higher CoQ10 levels compared to those with normal FT3 levels. Specifically, we found CoQ10 levels of 0.91 µg/ml in the low FT3 group versus 0.7 µg/ml in the normal FT3 group. Even when we normalized these levels with cholesterol, the difference was consistent, suggesting a metabolic aspect of hypothyroidism linked to lower thyroid hormone levels.
While these findings provide insight into how CoQ10 behaves in the context of thyroid hormone variation among COPD patients, they also raise questions about possible treatments. The elevated CoQ10 levels in patients with low FT3 suggest an adaptation mechanism similar to those seen in true hypothyroid states. However, whether CoQ10 supplementation could effectively address hypothyroidism still needs more rigorous study.
The results revealed an intriguing trend: patients exhibiting low FT3 levels had significantly higher CoQ10 levels compared to those with normal FT3 levels. Specifically, we found CoQ10 levels of 0.91 µg/ml in the low FT3 group versus 0.7 µg/ml in the normal FT3 group. Even when we normalized these levels with cholesterol, the difference was consistent, suggesting a metabolic aspect of hypothyroidism linked to lower thyroid hormone levels.
While these findings provide insight into how CoQ10 behaves in the context of thyroid hormone variation among COPD patients, they also raise questions about possible treatments. The elevated CoQ10 levels in patients with low FT3 suggest an adaptation mechanism similar to those seen in true hypothyroid states. However, whether CoQ10 supplementation could effectively address hypothyroidism still needs more rigorous study.
Read More
4
We evaluated the levels of Coenzyme Q10 (CoQ10) in patients with hypothyroidism and hyperthyroidism to understand its role in thyroid health. The study included participants from both groups, as well as a control group without thyroid issues, ensuring that no subjects had other cardiovascular or metabolic diseases that could interfere with the results.
Our findings showed that hypothyroid patients had a higher average level of CoQ10 in their blood compared to those with hyperthyroidism. Specifically, hypothyroid patients showed levels of 0.97 mcg/ml, while hyperthyroid patients had only 0.51 mcg/ml, with the control group at 0.73 mcg/ml. This suggests that patients with hypothyroidism may have a greater prevalence of higher CoQ10 levels.
However, we found that the differences were not enough to clearly separate those with normal thyroid function from those with either hypothyroidism or hyperthyroidism. While there is a noted inverse relationship between CoQ10 levels and certain thyroid hormones, this indicates that CoQ10 alone may not provide significant benefits for those specifically dealing with hypothyroidism. More research—especially longitudinal studies—is needed to see how treatment and therapy could potentially affect CoQ10 levels and overall thyroid health in these patients.
Our findings showed that hypothyroid patients had a higher average level of CoQ10 in their blood compared to those with hyperthyroidism. Specifically, hypothyroid patients showed levels of 0.97 mcg/ml, while hyperthyroid patients had only 0.51 mcg/ml, with the control group at 0.73 mcg/ml. This suggests that patients with hypothyroidism may have a greater prevalence of higher CoQ10 levels.
However, we found that the differences were not enough to clearly separate those with normal thyroid function from those with either hypothyroidism or hyperthyroidism. While there is a noted inverse relationship between CoQ10 levels and certain thyroid hormones, this indicates that CoQ10 alone may not provide significant benefits for those specifically dealing with hypothyroidism. More research—especially longitudinal studies—is needed to see how treatment and therapy could potentially affect CoQ10 levels and overall thyroid health in these patients.
Read More
4
We examined how coenzyme Q10 (Co-Q10) influences heart function in people with hypothyroidism. In this study, which involved 13 patients with primary hypothyroidism, we compared cardiac measurements such as the pre-ejection period (PEP) and the left ventricular ejection time (LVET) to those of healthy individuals.
Before treatment, we found that patients with hypothyroidism showed a prolonged PEP, reduced LVET, and a decreased LVET/PEP ratio, indicating that their hearts weren’t functioning optimally. However, after treatment with T4, a thyroid hormone, these measurements returned to normal levels.
Interestingly, within the same framework, we saw that administering 120 mg of Co-Q10 for a week significantly improved heart function in mild untreated thyrotoxic patients, leading to shortened PEP and increased stroke volume.
While we observed some positive trends with Co-Q10, it’s important to note that there was no significant benefit from Co-Q10 directly for those with hypothyroidism in the same manner as with T4 treatment. Thus, while our findings highlight the interplay between thyroid hormones and cardiac function, the role of Co-Q10 specifically for hypothyroidism remains unclear.
Before treatment, we found that patients with hypothyroidism showed a prolonged PEP, reduced LVET, and a decreased LVET/PEP ratio, indicating that their hearts weren’t functioning optimally. However, after treatment with T4, a thyroid hormone, these measurements returned to normal levels.
Interestingly, within the same framework, we saw that administering 120 mg of Co-Q10 for a week significantly improved heart function in mild untreated thyrotoxic patients, leading to shortened PEP and increased stroke volume.
While we observed some positive trends with Co-Q10, it’s important to note that there was no significant benefit from Co-Q10 directly for those with hypothyroidism in the same manner as with T4 treatment. Thus, while our findings highlight the interplay between thyroid hormones and cardiac function, the role of Co-Q10 specifically for hypothyroidism remains unclear.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Supports thyroid recovery
2 people found this helpful
I have bought this product multiple times for heart health. My husband has taken it for over five years, witnessing substantial improvement in his heart condition. I started it this year for my hypothyroidism and hyperlipidemia, and it appears to aid in restoring thyroid function while protecting cardiovascular health.
Read More
7.5
Boosted energy levels
27 people found this helpful
Coenzyme Q10 is a vital compound produced by the liver that aids in energy production. After five days of taking it, I noticed significant improvement in my energy and mood. My productivity increased, and I fell asleep more easily. This supplement is fantastic, particularly for addressing my hypothyroidism.
Read More
7.5
Irreplaceable supplement
This coenzyme is excellent! I take one capsule twice daily with meals; it enhances mitochondrial function, providing more energy and mental clarity. With my hypothyroidism, this supplement is indispensable. I noticed a notable boost in my energy levels and overall cognitive function.
Read More
Frequently Asked Questions
7.5
Boosted energy levels
27 people found this helpful
Coenzyme Q10 is a vital compound produced by the liver that aids in energy production. After five days of taking it, I noticed significant improvement in my energy and mood. My productivity increased, and I fell asleep more easily. This supplement is fantastic, particularly for addressing my hypothyroidism.
9
Supports thyroid recovery
2 people found this helpful
I have bought this product multiple times for heart health. My husband has taken it for over five years, witnessing substantial improvement in his heart condition. I started it this year for my hypothyroidism and hyperlipidemia, and it appears to aid in restoring thyroid function while protecting cardiovascular health.
7.5
Irreplaceable supplement
This coenzyme is excellent! I take one capsule twice daily with meals; it enhances mitochondrial function, providing more energy and mental clarity. With my hypothyroidism, this supplement is indispensable. I noticed a notable boost in my energy levels and overall cognitive function.
7
We explored the effects of a combination of magnesium, selenium, and coenzyme Q10 on the thyroid morphology in patients suffering from benign thyroid diseases, specifically looking at both hyperthyroidism and hypothyroidism. Our study involved 8 patients who received standard pharmacological treatment but also underwent additional therapy at our private institution.
Over a period of 2 to 4 years, we observed some remarkable changes. Initially, we addressed musculoskeletal issues and psychological stressors in our patients. Following this, thyroid morphology started to normalize, with improvements visible through ultrasound imaging. Notably, thyroid antibody levels declined in most patients, suggesting a positive response to the treatment.
However, it's essential to highlight that we could not assess the isolated impact of coenzyme Q10 on hypothyroidism specifically, as it was part of a broader treatment regimen. While we saw promising results, we encountered limited success in two cases where chronic thyroiditis had persisted for over ten years, suggesting that factors like fibrosis may influence treatment outcomes.
Overall, despite the small sample size, our findings challenge the idea that thyroid issues are perpetually autoimmune and irreversible, opening up new avenues for therapeutic options for patients with thyroid diseases.
Over a period of 2 to 4 years, we observed some remarkable changes. Initially, we addressed musculoskeletal issues and psychological stressors in our patients. Following this, thyroid morphology started to normalize, with improvements visible through ultrasound imaging. Notably, thyroid antibody levels declined in most patients, suggesting a positive response to the treatment.
However, it's essential to highlight that we could not assess the isolated impact of coenzyme Q10 on hypothyroidism specifically, as it was part of a broader treatment regimen. While we saw promising results, we encountered limited success in two cases where chronic thyroiditis had persisted for over ten years, suggesting that factors like fibrosis may influence treatment outcomes.
Overall, despite the small sample size, our findings challenge the idea that thyroid issues are perpetually autoimmune and irreversible, opening up new avenues for therapeutic options for patients with thyroid diseases.
4
We evaluated the levels of Coenzyme Q10 (CoQ10) in patients with hypothyroidism and hyperthyroidism to understand its role in thyroid health. The study included participants from both groups, as well as a control group without thyroid issues, ensuring that no subjects had other cardiovascular or metabolic diseases that could interfere with the results.
Our findings showed that hypothyroid patients had a higher average level of CoQ10 in their blood compared to those with hyperthyroidism. Specifically, hypothyroid patients showed levels of 0.97 mcg/ml, while hyperthyroid patients had only 0.51 mcg/ml, with the control group at 0.73 mcg/ml. This suggests that patients with hypothyroidism may have a greater prevalence of higher CoQ10 levels.
However, we found that the differences were not enough to clearly separate those with normal thyroid function from those with either hypothyroidism or hyperthyroidism. While there is a noted inverse relationship between CoQ10 levels and certain thyroid hormones, this indicates that CoQ10 alone may not provide significant benefits for those specifically dealing with hypothyroidism. More research—especially longitudinal studies—is needed to see how treatment and therapy could potentially affect CoQ10 levels and overall thyroid health in these patients.
Our findings showed that hypothyroid patients had a higher average level of CoQ10 in their blood compared to those with hyperthyroidism. Specifically, hypothyroid patients showed levels of 0.97 mcg/ml, while hyperthyroid patients had only 0.51 mcg/ml, with the control group at 0.73 mcg/ml. This suggests that patients with hypothyroidism may have a greater prevalence of higher CoQ10 levels.
However, we found that the differences were not enough to clearly separate those with normal thyroid function from those with either hypothyroidism or hyperthyroidism. While there is a noted inverse relationship between CoQ10 levels and certain thyroid hormones, this indicates that CoQ10 alone may not provide significant benefits for those specifically dealing with hypothyroidism. More research—especially longitudinal studies—is needed to see how treatment and therapy could potentially affect CoQ10 levels and overall thyroid health in these patients.
4
We examined how coenzyme Q10 (Co-Q10) influences heart function in people with hypothyroidism. In this study, which involved 13 patients with primary hypothyroidism, we compared cardiac measurements such as the pre-ejection period (PEP) and the left ventricular ejection time (LVET) to those of healthy individuals.
Before treatment, we found that patients with hypothyroidism showed a prolonged PEP, reduced LVET, and a decreased LVET/PEP ratio, indicating that their hearts weren’t functioning optimally. However, after treatment with T4, a thyroid hormone, these measurements returned to normal levels.
Interestingly, within the same framework, we saw that administering 120 mg of Co-Q10 for a week significantly improved heart function in mild untreated thyrotoxic patients, leading to shortened PEP and increased stroke volume.
While we observed some positive trends with Co-Q10, it’s important to note that there was no significant benefit from Co-Q10 directly for those with hypothyroidism in the same manner as with T4 treatment. Thus, while our findings highlight the interplay between thyroid hormones and cardiac function, the role of Co-Q10 specifically for hypothyroidism remains unclear.
Before treatment, we found that patients with hypothyroidism showed a prolonged PEP, reduced LVET, and a decreased LVET/PEP ratio, indicating that their hearts weren’t functioning optimally. However, after treatment with T4, a thyroid hormone, these measurements returned to normal levels.
Interestingly, within the same framework, we saw that administering 120 mg of Co-Q10 for a week significantly improved heart function in mild untreated thyrotoxic patients, leading to shortened PEP and increased stroke volume.
While we observed some positive trends with Co-Q10, it’s important to note that there was no significant benefit from Co-Q10 directly for those with hypothyroidism in the same manner as with T4 treatment. Thus, while our findings highlight the interplay between thyroid hormones and cardiac function, the role of Co-Q10 specifically for hypothyroidism remains unclear.
References
- Moncayo R, Moncayo H. Proof of concept of the WOMED model of benign thyroid disease: Restitution of thyroid morphology after correction of physical and psychological stressors and magnesium supplementation. BBA Clin. 2015;3:113. 10.1016/j.bbacli.2014.12.005
- Mancini A, Corbo GM, Gaballo A, Valente S, Gigliotti P, et al. Relationships between plasma CoQ10 levels and thyroid hormones in chronic obstructive pulmonary disease. Biofactors. 2005;25:201.
- Pandolfi C, Ferrari D, Stanic I, Pellegrini L. [Circulating levels of CoQ10 in hypo- and hyperthyroidism]. Minerva Endocrinol. 1994;19:139.
- Naito T. [Abnormal cardiac index measured by means of systolic time intervals and the effect of co-enzyme Q10 in thyroid disorders]. Nihon Naibunpi Gakkai Zasshi. 1986;62:619.
