Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.5
USERS' SCORE
Moderately Good
Based on 36 Reviews
7.6
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Coenzyme Q10 (Ubiquinone)
100 mg
†
Black Pepper Ext. (Piper nigrum) (fruit) (standardized to contain 95% Piperine) (BioPerine®)
5 mg
†
Top Medical Research Studies
9
We conducted a study to see how coenzyme Q10 (CoQ10) supplementation impacts migraine symptoms and inflammation. This randomized double-blind trial involved 45 non-menopausal women with episodic migraines.
Participants took either 400 mg/day of CoQ10 or a placebo for three months, while continuing their usual migraine medications. We observed a significant reduction in migraine frequency, severity, and duration in the CoQ10 group.
Additionally, CoQ10 levels and inflammatory markers showed some changes, specifically a reduction in certain proteins linked to inflammation. However, not all markers responded positively, indicating some limited effectiveness.
Participants took either 400 mg/day of CoQ10 or a placebo for three months, while continuing their usual migraine medications. We observed a significant reduction in migraine frequency, severity, and duration in the CoQ10 group.
Additionally, CoQ10 levels and inflammatory markers showed some changes, specifically a reduction in certain proteins linked to inflammation. However, not all markers responded positively, indicating some limited effectiveness.
Read More
8
We investigated whether coenzyme Q10 (CoQ10) could help reduce migraines. By examining five studies with 346 participants, we learned that CoQ10 may not significantly cut down on the number of attacks or their severity.
However, it appears to decrease the number of migraine days and duration each month. This suggests that while CoQ10 may not be a cure-all, it could help those suffering from migraines find some relief. Further research will be necessary to confirm these findings.
However, it appears to decrease the number of migraine days and duration each month. This suggests that while CoQ10 may not be a cure-all, it could help those suffering from migraines find some relief. Further research will be necessary to confirm these findings.
Read More
8
Co-Q10 potentially benefits migraine patients
We investigated how Coenzyme Q10 (Co-Q10) affects migraine symptoms in a well-structured clinical trial. Over the course of 12 weeks, 84 women aged 18 to 50 diagnosed with episodic migraines participated in a randomized, double-blind study, where they received either Co-Q10 (400 mg/day) or a placebo.
Upon analyzing the results, we observed some promising outcomes. Participants who took Co-Q10 experienced a significant reduction in malondialdehyde (MDA) levels, an indicator of oxidative stress. Additionally, there was a noteworthy increase in high-density lipoprotein cholesterol (HDL-C) levels, which is beneficial for overall heart health. We also noted a decrease in body fat percentage among those receiving Co-Q10.
However, while some improvements were documented, Co-Q10 did not show a significant effect on total antioxidant capacity or other lipid profile measures like low-density lipoprotein cholesterol and triglycerides. Therefore, while Co-Q10 may hold potential for enhancing certain health aspects in migraine sufferers, its overall impact on migraine management and other related parameters remains mixed.
Upon analyzing the results, we observed some promising outcomes. Participants who took Co-Q10 experienced a significant reduction in malondialdehyde (MDA) levels, an indicator of oxidative stress. Additionally, there was a noteworthy increase in high-density lipoprotein cholesterol (HDL-C) levels, which is beneficial for overall heart health. We also noted a decrease in body fat percentage among those receiving Co-Q10.
However, while some improvements were documented, Co-Q10 did not show a significant effect on total antioxidant capacity or other lipid profile measures like low-density lipoprotein cholesterol and triglycerides. Therefore, while Co-Q10 may hold potential for enhancing certain health aspects in migraine sufferers, its overall impact on migraine management and other related parameters remains mixed.
Read More
Most Useful Reviews
9
Migraine attacks nearly absent
16 people found this helpful
This product is effective; after regular use, my migraine attacks have almost disappeared. I feel energised and overall it has greatly improved my wellbeing.
Read More
9
Migraine relief
14 people found this helpful
The coenzyme Q10 has helped me eliminate migraines. It boosts energy for our immune system and aids oxygen absorption in cells, allowing the body to better resist infections.
Read More
9
Migraine nearly non-existent
9 people found this helpful
I was hesitant to switch to this product but was pleasantly surprised. Since taking 300 mg/day, I’ve maintained good energy levels, and my migraines have remained almost non-existent. I plan to recommend it to my mother as well.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.5
- All Researches
9
Nano-curcumin and CoQ10 reduce migraines
We explored how the combination of nano-curcumin and coenzyme Q10 (CoQ10) affects migraine symptoms and patients' quality of life. In a double-blind, placebo-controlled study involving 100 participants, we assessed the impacts on headache frequency, severity, and duration over eight weeks.
Our findings were promising: the group taking both nano-curcumin and CoQ10 showed significant improvements compared to those receiving the placebo or single supplements alone. Remarkably, this combination enhanced migraine-specific scores without any reported side effects. Overall, it highlights the potential benefits of these supplements in managing migraine.
Our findings were promising: the group taking both nano-curcumin and CoQ10 showed significant improvements compared to those receiving the placebo or single supplements alone. Remarkably, this combination enhanced migraine-specific scores without any reported side effects. Overall, it highlights the potential benefits of these supplements in managing migraine.
Read More
9
CoQ10 and L-carnitine aid migraines
We explored the impact of Coenzyme Q10 in combination with L-carnitine on migraine symptoms in a well-structured trial involving 56 participants aged 20-40. Over eight weeks, subjects received these supplements or a placebo.
Our findings show a substantial improvement in migraine-related aspects, including a decrease in headache severity, duration, and frequency, alongside lower serum lactate levels. This suggests that these supplements could be beneficial for those suffering from migraines.
Our findings show a substantial improvement in migraine-related aspects, including a decrease in headache severity, duration, and frequency, alongside lower serum lactate levels. This suggests that these supplements could be beneficial for those suffering from migraines.
Read More
9
We conducted a study to see how coenzyme Q10 (CoQ10) supplementation impacts migraine symptoms and inflammation. This randomized double-blind trial involved 45 non-menopausal women with episodic migraines.
Participants took either 400 mg/day of CoQ10 or a placebo for three months, while continuing their usual migraine medications. We observed a significant reduction in migraine frequency, severity, and duration in the CoQ10 group.
Additionally, CoQ10 levels and inflammatory markers showed some changes, specifically a reduction in certain proteins linked to inflammation. However, not all markers responded positively, indicating some limited effectiveness.
Participants took either 400 mg/day of CoQ10 or a placebo for three months, while continuing their usual migraine medications. We observed a significant reduction in migraine frequency, severity, and duration in the CoQ10 group.
Additionally, CoQ10 levels and inflammatory markers showed some changes, specifically a reduction in certain proteins linked to inflammation. However, not all markers responded positively, indicating some limited effectiveness.
Read More
9
We explored the effects of a daily supplement containing coenzyme Q10, feverfew, and magnesium on migraine prevention. In our observational study, which included adult migraine sufferers, participants took the supplement for three months after a one-month baseline phase.
Results revealed a significant reduction in migraine days, dropping from an average of 4.9 days to 1.3 days by the third month. Additionally, 75% of participants experienced at least a 50% reduction in migraine frequency.
The treatment was well tolerated and also appeared to improve anxiety and depressive symptoms, enhancing overall quality of life.
Results revealed a significant reduction in migraine days, dropping from an average of 4.9 days to 1.3 days by the third month. Additionally, 75% of participants experienced at least a 50% reduction in migraine frequency.
The treatment was well tolerated and also appeared to improve anxiety and depressive symptoms, enhancing overall quality of life.
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9
We aimed to explore how a nutraceutical combination of Ginkgolide B, Coenzyme Q10, Riboflavin, and Magnesium could help children with neurofibromatosis type 1 manage migraine without aura. Over six months, 18 school-aged children took this supplement twice a day and kept journals tracking their migraine symptoms.
Remarkably, we observed significant reductions in frequency, intensity, duration, and overall migraine-related disability. Our findings reveal that this nutraceutical blend may effectively alleviate migraine symptoms for these children, marking a promising step forward in managing headaches associated with NF1.
Remarkably, we observed significant reductions in frequency, intensity, duration, and overall migraine-related disability. Our findings reveal that this nutraceutical blend may effectively alleviate migraine symptoms for these children, marking a promising step forward in managing headaches associated with NF1.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 36 Reviews
7.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Migraine attacks nearly absent
16 people found this helpful
This product is effective; after regular use, my migraine attacks have almost disappeared. I feel energised and overall it has greatly improved my wellbeing.
Read More
9
Migraine relief
14 people found this helpful
The coenzyme Q10 has helped me eliminate migraines. It boosts energy for our immune system and aids oxygen absorption in cells, allowing the body to better resist infections.
Read More
9
Migraine nearly non-existent
9 people found this helpful
I was hesitant to switch to this product but was pleasantly surprised. Since taking 300 mg/day, I’ve maintained good energy levels, and my migraines have remained almost non-existent. I plan to recommend it to my mother as well.
Read More
9
Significant improvement
9 people found this helpful
Helps with migraine pain! I have chronic head, neck, and shoulder pain along with migraines. My doctors recommended 200mg of CoQ10 three times daily, and it has made a significant difference! When I ran out, the pain returned, highlighting its importance. A friend who underwent brain surgery also had his doctor suggest CoQ10. It seems to be gaining recognition worldwide among migraine sufferers! My doctor explained that it is something found throughout our bodies and could indicate lower levels in some individuals.
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7.5
Prevents migraines
3 people found this helpful
I use this in addition to my prescriptions for the prevention of migraines, and it definitely helps.
Read More
Frequently Asked Questions
6
Migraine improvement
19 people found this helpful
After a month of taking this product alongside Omega-3, I noticed significant improvements. I’ve suffered from migraines for around 30 years, and while I experienced three attacks this month, usually it’s more frequent. I'm optimistic that this product is helping me manage my migraines better.
8
Migraine-free for years
5 people found this helpful
This product has helped combat my migraine headaches and shoulder stiffness. After three months of use, I haven’t experienced migraine problems for nearly a decade, and it remains effective.
9
Proven effectiveness
Coenzyme Q10 has many documented therapeutic benefits. Personally, it has significantly reduced my migraine intensity and frequency after long-term use. I trust the brand, and I can assure you of its effectiveness.
7.5
Lower blood pressure
3 people found this helpful
CoQ10 acts as an antioxidant, protecting cells and aiding metabolism. It may slightly lower blood pressure and assist with heart failure, particularly when combined with medications. CoQ10 can also alleviate muscle pains and liver issues caused by statins and might help in migraine management, though results may take time.
9
Migraine attacks nearly absent
16 people found this helpful
This product is effective; after regular use, my migraine attacks have almost disappeared. I feel energised and overall it has greatly improved my wellbeing.
9
Reduces migraines
Coenzyme Q10 is beneficial for migraines. I've suffered from migraines for many years, but after taking it, my headaches have significantly reduced. I highly recommend it.
9
Migraine relief
2 people found this helpful
I read that CoQ10 has scientific support for helping migraines. After trying it, I've only had 3 or 4 migraines in over two years. I highly recommend it for headaches.
9
Migraine relief
14 people found this helpful
The coenzyme Q10 has helped me eliminate migraines. It boosts energy for our immune system and aids oxygen absorption in cells, allowing the body to better resist infections.
2
No relief for migraines
Unfortunately, this supplement did not seem to help my migraines at all.
4
We explored the potential role of coenzyme Q10 as a treatment option for migraines, particularly against the backdrop of mitochondrial dysfunction. This condition suggests that individuals with migraines may experience an imbalance between energy supply and demand in their brains. Through our examination of existing trials, we noted that some studies have found promising results for coenzyme Q10, especially among those who had lower levels of this nutrient before treatment.
However, it's important to be candid about the study’s limitations. Many of these trials lacked proper control groups or sufficient sample sizes to draw more conclusive results. Although the initial findings are intriguing, more rigorous research is needed to verify whether coenzyme Q10 can genuinely make a difference for migraine sufferers.
Overall, we recognize the potential that coenzyme Q10 holds as an adjunctive therapy for migraines, particularly as part of a personalized approach that considers individual nutrient deficiencies. By focusing on tailored treatments, we may pave the way for more effective management of migraines in the future.
However, it's important to be candid about the study’s limitations. Many of these trials lacked proper control groups or sufficient sample sizes to draw more conclusive results. Although the initial findings are intriguing, more rigorous research is needed to verify whether coenzyme Q10 can genuinely make a difference for migraine sufferers.
Overall, we recognize the potential that coenzyme Q10 holds as an adjunctive therapy for migraines, particularly as part of a personalized approach that considers individual nutrient deficiencies. By focusing on tailored treatments, we may pave the way for more effective management of migraines in the future.
8
We explored how coenzyme Q10 (CoQ10) can influence migraines by reviewing randomized controlled trials that compared this supplement to placebos.
The systematic analysis revealed that CoQ10 has a beneficial impact on reducing both the frequency and duration of migraine attacks.
This is promising for those suffering from migraines, as it suggests that CoQ10 may aid in managing their symptoms effectively.
The systematic analysis revealed that CoQ10 has a beneficial impact on reducing both the frequency and duration of migraine attacks.
This is promising for those suffering from migraines, as it suggests that CoQ10 may aid in managing their symptoms effectively.
7
We explored the effectiveness of Coenzyme Q10 (CoQ10) in preventing migraines. The findings suggest that CoQ10 has limited evidence supporting its use, classified as Level C. This means that while some patients may benefit, the overall results are not strong enough to warrant a confident recommendation. Importantly, adverse side effects appear low, making it a relatively safe option. However, we must approach it with care, looking at other proven alternatives for migraine prevention.
8
We delved into the effectiveness of coenzyme Q10 (CoQ10) as a treatment for migraine headaches, alongside other dietary supplements known for their potential benefits in headache management. The evidence highlights CoQ10's prominent role in mitochondrial energy metabolism, which is crucial since migraines may stem from energy deficits in our bodies.
Various studies indicate that incorporating CoQ10 into daily routines can lead to significant improvements in migraine symptoms. For example, consistent intake of CoQ10 may help in reducing the frequency of migraine attacks, especially when combined with other essential nutrients like magnesium and vitamins B and D.
Overall, we found that a combination of these supplements could serve as an effective, budget-friendly strategy for individuals seeking relief from migraines. This suggests that CoQ10, among other nutrients, deserves a place in dietary approaches to migraine prevention.
Various studies indicate that incorporating CoQ10 into daily routines can lead to significant improvements in migraine symptoms. For example, consistent intake of CoQ10 may help in reducing the frequency of migraine attacks, especially when combined with other essential nutrients like magnesium and vitamins B and D.
Overall, we found that a combination of these supplements could serve as an effective, budget-friendly strategy for individuals seeking relief from migraines. This suggests that CoQ10, among other nutrients, deserves a place in dietary approaches to migraine prevention.
8
Co-Q10 potentially benefits migraine patients
We investigated how Coenzyme Q10 (Co-Q10) affects migraine symptoms in a well-structured clinical trial. Over the course of 12 weeks, 84 women aged 18 to 50 diagnosed with episodic migraines participated in a randomized, double-blind study, where they received either Co-Q10 (400 mg/day) or a placebo.
Upon analyzing the results, we observed some promising outcomes. Participants who took Co-Q10 experienced a significant reduction in malondialdehyde (MDA) levels, an indicator of oxidative stress. Additionally, there was a noteworthy increase in high-density lipoprotein cholesterol (HDL-C) levels, which is beneficial for overall heart health. We also noted a decrease in body fat percentage among those receiving Co-Q10.
However, while some improvements were documented, Co-Q10 did not show a significant effect on total antioxidant capacity or other lipid profile measures like low-density lipoprotein cholesterol and triglycerides. Therefore, while Co-Q10 may hold potential for enhancing certain health aspects in migraine sufferers, its overall impact on migraine management and other related parameters remains mixed.
Upon analyzing the results, we observed some promising outcomes. Participants who took Co-Q10 experienced a significant reduction in malondialdehyde (MDA) levels, an indicator of oxidative stress. Additionally, there was a noteworthy increase in high-density lipoprotein cholesterol (HDL-C) levels, which is beneficial for overall heart health. We also noted a decrease in body fat percentage among those receiving Co-Q10.
However, while some improvements were documented, Co-Q10 did not show a significant effect on total antioxidant capacity or other lipid profile measures like low-density lipoprotein cholesterol and triglycerides. Therefore, while Co-Q10 may hold potential for enhancing certain health aspects in migraine sufferers, its overall impact on migraine management and other related parameters remains mixed.
7
We explored the effects of coenzyme Q10 on migraine headaches through a comprehensive review of existing studies. Our goal was to determine if this supplement can effectively reduce the frequency of migraine attacks, as well as their severity and duration.
Upon reviewing various studies that included adult participants between the ages of 18 and 65, we found promising results regarding the frequency of migraines. Coenzyme Q10 appeared to help decrease how often these painful episodes occurred.
However, when it came to the severity and duration of the migraines, the results were mixed. Some studies showed slight improvements, while others did not demonstrate significant benefits. Importantly, we noted that participants reported no concerning side effects from taking coenzyme Q10, which is great news for those looking for natural alternatives to traditional medications.
Overall, we believe that coenzyme Q10 could be a valuable option for individuals who experience adverse reactions to conventional migraine treatments and prefer a more holistic approach.
Upon reviewing various studies that included adult participants between the ages of 18 and 65, we found promising results regarding the frequency of migraines. Coenzyme Q10 appeared to help decrease how often these painful episodes occurred.
However, when it came to the severity and duration of the migraines, the results were mixed. Some studies showed slight improvements, while others did not demonstrate significant benefits. Importantly, we noted that participants reported no concerning side effects from taking coenzyme Q10, which is great news for those looking for natural alternatives to traditional medications.
Overall, we believe that coenzyme Q10 could be a valuable option for individuals who experience adverse reactions to conventional migraine treatments and prefer a more holistic approach.
8
CoQ10 shows promise for migraines
We examined the potential of coenzyme Q10 (CoQ10) as a preventive treatment for migraines. Evidence indicates that CoQ10 can effectively help reduce the frequency of migraines with minimal side effects.
Our findings suggest that its efficacy is comparable to conventional treatments like topiramate and propranolol, making it an appealing option for those seeking an alternative.
With its promising profile, CoQ10 could be a first-line treatment for migraine prevention, especially in children and adolescents.
Our findings suggest that its efficacy is comparable to conventional treatments like topiramate and propranolol, making it an appealing option for those seeking an alternative.
With its promising profile, CoQ10 could be a first-line treatment for migraine prevention, especially in children and adolescents.
References
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- Sazali S, Badrin S, Norhayati MN, Idris NS. Coenzyme Q10 supplementation for prophylaxis in adult patients with migraine-a meta-analysis. BMJ Open. 2021;11:e039358. 10.1136/bmjopen-2020-039358
- Lisicki M, Schoenen J. Metabolic treatments of migraine. Expert Rev Neurother. 2020;20:295. 10.1080/14737175.2020.1729130
- Parohan M, Sarraf P, Javanbakht MH, Foroushani AR, Ranji-Burachaloo S, et al. The synergistic effects of nano-curcumin and coenzyme Q10 supplementation in migraine prophylaxis: a randomized, placebo-controlled, double-blind trial. Nutr Neurosci. 2021;24:317. 10.1080/1028415X.2019.1627770
- Moscano F, Guiducci M, Maltoni L, Striano P, Ledda MG, et al. An observational study of fixed-dose Tanacetum parthenium nutraceutical preparation for prophylaxis of pediatric headache. Ital J Pediatr. 2019;45:36. 10.1186/s13052-019-0624-z
- Parohan M, Sarraf P, Javanbakht MH, Ranji-Burachaloo S, Djalali M. Effect of coenzyme Q10 supplementation on clinical features of migraine: a systematic review and dose-response meta-analysis of randomized controlled trials. Nutr Neurosci. 2020;23:868. 10.1080/1028415X.2019.1572940
- Hajihashemi P, Askari G, Khorvash F, Reza Maracy M, Nourian M. The effects of concurrent Coenzyme Q10, L-carnitine supplementation in migraine prophylaxis: A randomized, placebo-controlled, double-blind trial. Cephalalgia. 2019;39:648. 10.1177/0333102418821661
- Zeng Z, Li Y, Lu S, Huang W, Di W. Efficacy of CoQ10 as supplementation for migraine: A meta-analysis. Acta Neurol Scand. 2019;139:284. 10.1111/ane.13051
- Dahri M, Tarighat-Esfanjani A, Asghari-Jafarabadi M, Hashemilar M. Oral coenzyme Q10 supplementation in patients with migraine: Effects on clinical features and inflammatory markers. Nutr Neurosci. 2019;22:607. 10.1080/1028415X.2017.1421039
- Guilbot A, Bangratz M, Ait Abdellah S, Lucas C. A combination of coenzyme Q10, feverfew and magnesium for migraine prophylaxis: a prospective observational study. BMC Complement Altern Med. 2017;17:433. 10.1186/s12906-017-1933-7
- Shoeibi A, Olfati N, Soltani Sabi M, Salehi M, Mali S, et al. Effectiveness of coenzyme Q10 in prophylactic treatment of migraine headache: an open-label, add-on, controlled trial. Acta Neurol Belg. 2017;117:103. 10.1007/s13760-016-0697-z
- Gaul C, Diener HC, Danesch U. Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial. J Headache Pain. 2015;16:516. 10.1186/s10194-015-0516-6
- Carotenuto M, Esposito M. Nutraceuticals safety and efficacy in migraine without aura in a population of children affected by neurofibromatosis type I. Neurol Sci. 2013;34:1905. 10.1007/s10072-013-1403-z
- Pringsheim T, Davenport W, Mackie G, Worthington I, Aubé M, et al. Canadian Headache Society guideline for migraine prophylaxis. Can J Neurol Sci. 2012;39:S1.
- Slater SK, Nelson TD, Kabbouche MA, LeCates SL, Horn P, et al. A randomized, double-blinded, placebo-controlled, crossover, add-on study of CoEnzyme Q10 in the prevention of pediatric and adolescent migraine. Cephalalgia. 2011;31:897. 10.1177/0333102411406755
- Schiapparelli P, Allais G, Castagnoli Gabellari I, Rolando S, Terzi MG, et al. Non-pharmacological approach to migraine prophylaxis: part II. Neurol Sci. 2010;31 Suppl 1:S137. 10.1007/s10072-010-0307-4
- Tavasoli A, Rezazadeh M, Kachuei M. Eyebrow bleeding as a rare migraine symptom: a case report. Ann Med Surg (Lond). 2024;86:7377. 10.1097/MS9.0000000000002655
- Hajhashemy Z, Golpour-Hamedani S, Eshaghian N, Sadeghi O, Khorvash F, et al. Practical supplements for prevention and management of migraine attacks: a narrative review. Front Nutr. 2024;11:1433390. 10.3389/fnut.2024.1433390
- Jiménez-Jiménez FJ, Alonso-Navarro H, García-Martín E, Espada-Rubio S, Agúndez JAG. Oxidative Stress and Migraine. Mol Neurobiol. 2024;61:8344. 10.1007/s12035-024-04114-7
- Hannigan IP, Rosengren SM, Di Tanna GL, Watson SRD, Welgampola MS. Effects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study. Intern Med J. 2024;54:916. 10.1111/imj.16314
- Dahri M, Sarafan Sadeghi A, Pahlavani N, Nattagh-Eshtivani E, Hashemilar M, et al. The Effects of Coenzyme Q10 Supplementation on Oxidative Status and Lipid Profile in Migraine Patients: A Randomized Double-Blinded Controlled Clinical Trial. Clin Nutr Res. 2023;12:257. 10.7762/cnr.2023.12.4.257
- Ebrahimi A, Kamyab A, Hosseini S, Ebrahimi S, Ashkani-Esfahani S. Involvement of Coenzyme Q10 in Various Neurodegenerative and Psychiatric Diseases. Biochem Res Int. 2023;2023:5510874. 10.1155/2023/5510874
- Stearns SA, Xun H, Haddad A, Rinkinen J, Bustos VP, et al. Therapeutic Options for Migraines in the Microsurgical Patient: A Scoping Review. Plast Reconstr Surg. 2024;153:988e. 10.1097/PRS.0000000000010861
- Yaghini O, Hoseini N, Ghazavi MR, Mansouri V, Nasiri J, et al. A Comparative Study on the Efficacy of Coenzyme Q10 and Amitriptyline in the Prophylactic Treatment of Migraine Headaches in Children: A Randomized Controlled Trial. Adv Biomed Res. 2022;11:43. 10.4103/abr.abr_235_20
- Ariyanfar S, Razeghi Jahromi S, Togha M, Ghorbani Z. Review on Headache Related to Dietary Supplements. Curr Pain Headache Rep. 2022;26:193. 10.1007/s11916-022-01019-9
- Grech O, Mollan SP, Wakerley BR, Fulton D, Lavery GG, et al. The Role of Metabolism in Migraine Pathophysiology and Susceptibility. Life (Basel). 2021;11. 10.3390/life11050415
- Kaur K, Hernandez V, Al Hajaj SW, Ebrahim AM, Razack M, et al. The Efficacy of Herbal Supplements and Nutraceuticals for Prevention of Migraine: Can They Help?. Cureus. 2021;13:e14868. 10.7759/cureus.14868
- Vikelis M, Dermitzakis EV, Vlachos GS, Soldatos P, Spingos KC, et al. Open Label Prospective Experience of Supplementation with a Fixed Combination of Magnesium, Vitamin B2, Feverfew, Andrographis Paniculata and Coenzyme Q10 for Episodic Migraine Prophylaxis. J Clin Med. 2020;10. 10.3390/jcm10010067
- Onofri A, Necozione S, Tozzi E. Complementary and alternative medicine (CAM) in headache of children and adolescents: open-label Italian study. Clin Ter. 2020;171:e393. 10.7417/CT.2020.2246
