Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 14 Reviews
8.7
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Coenzyme Q10 (Ubiquinone)
100 mg
Black Pepper Ext. (Piper nigrum) (fruit) (standardized to contain 95% Piperine) (BioPerine®)
5 mg

Top Medical Research Studies

We investigated the potential benefits of coenzyme Q10 (CoQ10) supplementation in patients recovering from acute ischemic stroke. In this double-blind, randomized placebo-controlled study, fifty hospitalized patients were divided into two groups; one received 600 mg of CoQ10 daily for 30 days, while the other received a placebo starting 24 hours post-stroke.

Our findings revealed notable improvements among those taking CoQ10. The group supplemented with CoQ10 showed significant reductions in harmful substances linked to oxidative stress, such as malondialdehyde (MDA) and inflammatory interleukin-6 (IL-6). Additionally, we observed increases in beneficial antioxidants, including superoxide dismutase (SOD) and brain-derived neurotrophic factor (BDNF), suggesting that CoQ10 may aid in neuroprotection and recovery after a stroke.

While some biomarkers did not show significant change, the overall results suggest that CoQ10 could be a valuable addition to rehabilitation programs for stroke patients, potentially improving recovery outcomes.
Read More

Most Useful Reviews

9.5
Prevents heatstroke
I find Coenzyme Q10 essential for surviving summer in Japan as it helps with my weak autonomic nervous system. Taking it after breakfast has prevented heatstroke during my commutes, which I previously suffered from.
Read More
9.5
Stroke effect noted
Doctor's Best Coenzyme Q10 has improved my mother's condition after her early stroke and atrial fibrillation. I’ve noticed positive effects, and I intend to repurchase for continued support.
Read More
9.5
Protects against strokes
Coenzyme Q10 is an excellent supplement that helps protect against strokes and heart attacks while producing energy and sustaining youthfulness.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
We investigated the potential benefits of coenzyme Q10 (CoQ10) supplementation in patients recovering from acute ischemic stroke. In this double-blind, randomized placebo-controlled study, fifty hospitalized patients were divided into two groups; one received 600 mg of CoQ10 daily for 30 days, while the other received a placebo starting 24 hours post-stroke.

Our findings revealed notable improvements among those taking CoQ10. The group supplemented with CoQ10 showed significant reductions in harmful substances linked to oxidative stress, such as malondialdehyde (MDA) and inflammatory interleukin-6 (IL-6). Additionally, we observed increases in beneficial antioxidants, including superoxide dismutase (SOD) and brain-derived neurotrophic factor (BDNF), suggesting that CoQ10 may aid in neuroprotection and recovery after a stroke.

While some biomarkers did not show significant change, the overall results suggest that CoQ10 could be a valuable addition to rehabilitation programs for stroke patients, potentially improving recovery outcomes.
Read More

User Reviews

USERS' SCORE
Good
Based on 14 Reviews
8.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Prevents heatstroke
I find Coenzyme Q10 essential for surviving summer in Japan as it helps with my weak autonomic nervous system. Taking it after breakfast has prevented heatstroke during my commutes, which I previously suffered from.
Read More
9.5
Stroke effect noted
Doctor's Best Coenzyme Q10 has improved my mother's condition after her early stroke and atrial fibrillation. I’ve noticed positive effects, and I intend to repurchase for continued support.
Read More
9.5
Protects against strokes
Coenzyme Q10 is an excellent supplement that helps protect against strokes and heart attacks while producing energy and sustaining youthfulness.
Read More
9.5
Supports heart function
This coenzyme, combined with black pepper extract, is crucial for individuals over 40. It aids energy production, combats oxidative stress, and is key for supporting heart health, thus helping to reduce stroke risks.
Read More
8.3
Prevents stroke risk
I take CoQ10 to support my heart health, which has been under threat due to PTSD. While I don’t feel its effects directly, it has significantly reduced my risk of experiencing a stroke or heart attack, especially in managing my arrhythmia.
Read More

Frequently Asked Questions

A stroke occurs when the blood supply to a part of the brain is interrupted or reduced, preventing brain tissue from getting oxygen and nutrients. This can happen in two primary ways: an ischemic stroke, which occurs when a blood vessel supplying blood to the brain is obstructed, often due to a blood clot; and a hemorrhagic stroke, which occurs when a blood vessel in the brain bursts, leading to bleeding in or around the brain. The severity and outcome of a stroke can vary widely depending on the type, location, and amount of brain tissue affected, as well as the speed with which medical treatment is received.

Recognizing the symptoms of a stroke is crucial for prompt treatment and recovery. Common signs include sudden numbness or weakness in the face, arm, or leg, especially on one side of the body, confusion, trouble speaking or understanding speech, vision problems in one or both eyes, and difficulty walking, which may include dizziness or loss of balance coordination. The acronym FAST can help remember the key signs: Face drooping, Arm weakness, Speech difficulty, and Time to call emergency services. If you or someone you know exhibits these symptoms, it's vital to seek immediate medical attention, as timely intervention can significantly improve outcomes.

Coenzyme Q10, often abbreviated as CoQ10, is a naturally occurring antioxidant that is found in the cells of the body. It plays a crucial role in the production of energy within mitochondria, which are the powerhouses of our cells. CoQ10 is important for maintaining cellular energy levels and overall health, as it assists in the conversion of food into energy. Additionally, it helps protect cells from oxidative damage, which is linked to various conditions such as heart disease and aging.

As a dietary supplement, CoQ10 is popular for its potential benefits, including promoting heart health, improving energy levels, and supporting cognitive function. It's particularly beneficial for individuals who are taking statin medications, as these drugs can lower natural CoQ10 levels in the body. While more research is needed to determine its efficacy fully, many users have reported positive experiences. If you’re considering adding CoQ10 to your supplement routine, it’s best to consult with a healthcare professional to determine the appropriate dosage and ensure it fits your health needs.

Based on user reviews, the timeframe for noticing results from Coenzyme Q10 can vary significantly among individuals. Some users report immediate benefits, while others mention it may take weeks to observe tangible effects. For instance, one user noted improvements in their mother’s condition post-stroke, indicating positive effects that make continued use worthwhile (Read Review). Another reviewer shared their experiences in stroke recovery, suggesting that CoQ10 yields positive results but warns that individual responses can differ (Read Review).

Recent research indicates that Coenzyme Q10 (CoQ10) may have potential benefits for stroke recovery. A study involving fifty patients recovering from acute ischemic stroke evaluated the effects of a 600 mg daily dose of CoQ10 over 30 days compared to a placebo. The findings showed significant improvements in oxidative stress markers, with reductions in harmful substances like malondialdehyde and interleukin-6, alongside increases in beneficial antioxidants such as superoxide dismutase and brain-derived neurotrophic factor. This suggests that CoQ10 may offer neuroprotective effects and enhance recovery outcomes for stroke patients [1].

Based on user reviews, many individuals have reported significant improvements in various health conditions associated with Coenzyme Q10 supplementation. Some users claim that the supplement has been essential for managing their autonomic nervous system, particularly in climates that pose risks such as heatstroke (Read Review). Others have experienced marked enhancements in cardiovascular health, with family members reporting positive changes after strokes or heart-related issues, leading to repeated purchases for continued support (Read Review). Furthermore, users have indicated that CoQ10 aids in energy production and may reduce the risk of serious events like strokes and heart attacks (Read Review).

Additionally, several testimonies highlight Coenzyme Q10's role in overall wellness, including recovery from childbirth and combating the effects of medications that could lead to adverse health outcomes (Read Review). Users also note its ability to support heart health and potentially lower blood pressure, which is especially beneficial for older adults and those with pre-existing conditions (Read Review). Nevertheless, it’s important to remember that individual results can vary, and experiences may differ from person to person.

Based on user reviews, many individuals have reported positive outcomes when combining Coenzyme Q10 with other supplements for stroke management and overall heart health. One user highlighted the benefits of taking CoQ10 alongside omega-3 fatty acids, stating that this combination not only provides energizing effects but also aids in reducing the risk of blood clots and strokes (Read Review). Another reviewer mentioned the importance of CoQ10 in conjunction with black pepper extract, emphasizing its role in energy production, combating oxidative stress, and minimizing stroke risks, particularly for those over 40 (Read Review).

Moreover, users have shared that CoQ10 plays a supportive role in their recovery from strokes and heart attacks while being effective in combination with other treatments for managing heart conditions and side effects of medications like Lipitor (Read Review). Overall, these testimonials suggest that many users find synergistic benefits when combining Coenzyme Q10 with other complementary supplements, contributing to improved cardiovascular health and reduced risk of severe health issues (Read Review).

The optimal dose for Coenzyme Q10 (CoQ10) when treating stroke appears to be 600 mg daily. A recent double-blind, randomized placebo-controlled study involving fifty hospitalized patients recovering from acute ischemic stroke found that this dosage led to significant improvements in several key biomarkers linked to oxidative stress and inflammation. Specifically, patients receiving 600 mg of CoQ10 exhibited reductions in harmful substances like malondialdehyde (MDA) and interleukin-6 (IL-6), while also showing increases in beneficial antioxidants such as superoxide dismutase (SOD) and brain-derived neurotrophic factor (BDNF) [1].

These results suggest that CoQ10 may serve as a valuable supplement in rehabilitation programs for stroke patients, potentially enhancing neuroprotection and improving recovery outcomes. If you or someone you know is considering CoQ10 as part of stroke recovery, 600 mg per day may be an effective starting point based on this research, but always consult with a healthcare professional before starting any new supplementation regimen.

9.5
Stroke effect noted
Doctor's Best Coenzyme Q10 has improved my mother's condition after her early stroke and atrial fibrillation. I’ve noticed positive effects, and I intend to repurchase for continued support.
8.8
Recovery from stroke
CoQ10 has been effective for my patients with various arrhythmias and conditions like connective tissue diseases and mitochondrial deficiency. It yields positive results in stroke recovery, but individual intolerance should always be considered.
9.5
Prevents heatstroke
I find Coenzyme Q10 essential for surviving summer in Japan as it helps with my weak autonomic nervous system. Taking it after breakfast has prevented heatstroke during my commutes, which I previously suffered from.
8.8
Heart and stroke recovery
Since childbirth, I've taken Coenzyme Q10 to restore my health. It’s beneficial for heart and blood vessel diseases and aids in recovery from strokes and heart attacks, while also helping with neurological issues and slowing age-related changes.
7.5
Improves stroke treatment
Coenzyme Q10 is known for its antioxidant properties, improving immune function and preventing diseases related to vitamin deficiency. I buy it for my parents to help lower their blood pressure and reduce their risk of stroke and other cardiovascular conditions.
8.8
Fights against strokes
Coenzyme Q10 is a powerful antioxidant that combats free radicals, prevents premature aging, and reduces the risk of blood clots, heart attacks, and strokes. I regularly take it alongside omega-3 and feel energised.
9.5
Supports heart function
This coenzyme, combined with black pepper extract, is crucial for individuals over 40. It aids energy production, combats oxidative stress, and is key for supporting heart health, thus helping to reduce stroke risks.
7.5
Supports stroke prevention
Coenzyme Q10 is essential for countering the side effects of hyperlipidemia medications like Lipitor, which can lead to stroke. Its long-term use helps maintain musculoskeletal health, and I find it has good cost performance without significant rejection.
7.5
Assists stroke recovery
I believe Coenzyme Q10 is a vital antioxidant for everyone, particularly for those recovering from strokes, heart attacks, or suffering conditions like coronary heart disease.
We investigated the potential benefits of coenzyme Q10 (CoQ10) supplementation in patients recovering from acute ischemic stroke. In this double-blind, randomized placebo-controlled study, fifty hospitalized patients were divided into two groups; one received 600 mg of CoQ10 daily for 30 days, while the other received a placebo starting 24 hours post-stroke.

Our findings revealed notable improvements among those taking CoQ10. The group supplemented with CoQ10 showed significant reductions in harmful substances linked to oxidative stress, such as malondialdehyde (MDA) and inflammatory interleukin-6 (IL-6). Additionally, we observed increases in beneficial antioxidants, including superoxide dismutase (SOD) and brain-derived neurotrophic factor (BDNF), suggesting that CoQ10 may aid in neuroprotection and recovery after a stroke.

While some biomarkers did not show significant change, the overall results suggest that CoQ10 could be a valuable addition to rehabilitation programs for stroke patients, potentially improving recovery outcomes.

References

  1. Mojaver A, Khazaei M, Ahmadpanah M, Zarei M, Soleimani Asl S, et al. Dietary intake of coenzyme Q10 reduces oxidative stress in patients with acute ischemic stroke: a double-blind, randomized placebo-controlled study. Neurol Res. 2025. doi:10.1080/01616412.2025.2470712
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