Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
USERS' SCORE
Good
Based on 10 Reviews
8.5
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Magnesium (from 2,000 mg magnesium lysinate glycinate chelate) (Albion®)
200 mg
48%

Top Medical Research Studies

9
Magnesium intake linked to reduced hypertension
We explored the connection between dietary magnesium intake and hypertension along with other health issues in US adults. In our study, we analyzed data from over 24,000 people, taking into account various lifestyle factors.

We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.

These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns.
Read More
8
Magnesium effectively lowers blood pressure
We explored how magnesium supplementation can affect systolic blood pressure (SBP) in the general population. Through careful analysis of placebo-controlled, randomized clinical trials, we focused on understanding the optimal dosages and treatment durations necessary to achieve significant reductions in SBP. Past findings revealed that magnesium could reduce SBP by an average of 2.79 mm Hg, and our goal was to dive deeper into these results.

Our meta-analysis showed promising outcomes. Specifically, we noticed that magnesium taken at lower doses, particularly ≤360 mg per day, led to a notable decrease in SBP of about 3.03 mm Hg, especially when the treatment duration exceeded three months. This suggests that for those looking to manage their blood pressure, longer-term use of magnesium at these dosages may be beneficial.

While we found encouraging evidence pointing to the effectiveness of magnesium in lowering SBP, we acknowledge the importance of further studies. These future investigations should focus on varied dosages and longer follow-up periods to strengthen our understanding and provide tailored recommendations for individuals seeking to utilize magnesium in their hypertension management strategies.
Read More
8
Magnesium depletion predicts mortality risk
We examined how the magnesium depletion score (MDS) affects mortality risks in individuals with hypertension. By analyzing data from over 12,000 participants in a national health survey, we discovered that those with higher MDS levels significantly faced increased risks of both all-cause and cardiovascular deaths.

Our findings highlighted that individuals grouped in the higher MDS category had an elevated mortality risk compared to those in the lower and middle categories, underscoring the potential of MDS as a simple tool for identifying at-risk patients.

In essence, maintaining adequate magnesium levels could play a critical role in improving health outcomes for those suffering from hypertension.
Read More

Most Useful Reviews

8
Insulin Sensitivity
4 people found this helpful
I always buy magnesium for my elderly mother with diabetes. It enhances tissue sensitivity to insulin and has helped lessen her reliance on insulin injections while keeping hypertension at bay. I recommend it especially for women.
Read More
10
Reduces blood pressure
2 people found this helpful
BEST EVER MAG! I tried other brands and different forms with no effect on my hypertension, but after taking this magnesium, my blood pressure became normal. It's highly recommended. I'm on my third bottle already. AWESOME!
Read More
9
Sound Sleep
2 people found this helpful
A strong sleep aid that reduces hypertension and promotes relaxation. It has excellent assimilation and should be taken at night for the best effect.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
  • All Researches
9
Magnesium improves pregnancy hypertension
We conducted a retrospective study to investigate how magnesium sulfate paired with labetalol affects vascular health and pregnancy outcomes in women with preeclampsia—a serious condition that can occur during pregnancy characterized by high blood pressure.

Our analysis focused on clinical data from 262 women treated for preeclampsia. The patients were divided into two groups: one group received magnesium sulfate alone, while the other group was treated with both magnesium sulfate and labetalol. By measuring key indicators such as nitric oxide and endothelin-1 levels, along with blood pressure readings, we aimed to determine the effectiveness of these treatments.

The results showed that the combination of magnesium sulfate and labetalol notably improved vascular function and pregnancy outcomes for these women. Not only did this treatment help in better controlling high blood pressure during pregnancy, but it also reduced the chances of adverse outcomes for both mothers and babies. Importantly, the study found this combined treatment to be as safe as using magnesium sulfate alone.

This reinforces the idea that magnesium can play a significant role in treating hypertension during pregnancy, especially when paired with other medications like labetalol.
Read More
9
Magnesium's effects on PAH treatment
We examined an experimental model of pulmonary arterial hypertension (PAH) induced by monocrotaline in rats. Our research focused on the combined effects of Magnesium sulfate along with Rosuvastatin and Sildenafil, which were administered two weeks after the initial MCT injection.

Using measures like the Fulton Index and various cardiac dimensions, we observed improvements in right ventricular function and markers of oxidative stress. Notably, Magnesium sulfate appeared to work well with Rosuvastatin, which is known for its anti-inflammatory properties, enhancing the overall treatment effectiveness on pulmonary hypertension.

However, since Magnesium was administered in combination with these other treatments, we could not determine its isolated benefits on hypertension specifically. The study did highlight the importance of multi-pronged approaches in tackling such complex conditions, suggesting that further research might clarify Magnesium's unique contributions to managing hypertension.
Read More
We examined a cohort of neonates born at or above 36 weeks gestation to assess the impact of antenatal magnesium sulfate on hypoxic-ischemic encephalopathy linked to hypertensive disorders of pregnancy.

Our analysis revealed that these disorders significantly increase the risk of moderate to severe brain injury. Importantly, we observed that receiving magnesium sulfate reduced the odds of developing hypoxic-ischemic encephalopathy in affected infants.

However, it’s crucial to understand that while our study shows an association, it does not establish a cause-and-effect relationship.
Read More
9
Magnesium intake linked to reduced hypertension
We explored the connection between dietary magnesium intake and hypertension along with other health issues in US adults. In our study, we analyzed data from over 24,000 people, taking into account various lifestyle factors.

We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.

These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns.
Read More
8
Magnesium effectively lowers blood pressure
We explored how magnesium supplementation can affect systolic blood pressure (SBP) in the general population. Through careful analysis of placebo-controlled, randomized clinical trials, we focused on understanding the optimal dosages and treatment durations necessary to achieve significant reductions in SBP. Past findings revealed that magnesium could reduce SBP by an average of 2.79 mm Hg, and our goal was to dive deeper into these results.

Our meta-analysis showed promising outcomes. Specifically, we noticed that magnesium taken at lower doses, particularly ≤360 mg per day, led to a notable decrease in SBP of about 3.03 mm Hg, especially when the treatment duration exceeded three months. This suggests that for those looking to manage their blood pressure, longer-term use of magnesium at these dosages may be beneficial.

While we found encouraging evidence pointing to the effectiveness of magnesium in lowering SBP, we acknowledge the importance of further studies. These future investigations should focus on varied dosages and longer follow-up periods to strengthen our understanding and provide tailored recommendations for individuals seeking to utilize magnesium in their hypertension management strategies.
Read More

User Reviews

USERS' SCORE
Good
Based on 10 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8
Insulin Sensitivity
4 people found this helpful
I always buy magnesium for my elderly mother with diabetes. It enhances tissue sensitivity to insulin and has helped lessen her reliance on insulin injections while keeping hypertension at bay. I recommend it especially for women.
Read More
10
Reduces blood pressure
2 people found this helpful
BEST EVER MAG! I tried other brands and different forms with no effect on my hypertension, but after taking this magnesium, my blood pressure became normal. It's highly recommended. I'm on my third bottle already. AWESOME!
Read More
9
Sound Sleep
2 people found this helpful
A strong sleep aid that reduces hypertension and promotes relaxation. It has excellent assimilation and should be taken at night for the best effect.
Read More
10
Normalizes blood pressure
1 people found this helpful
My husband has hypertension and started taking this magnesium every morning for the past few months. With the doctor’s advice, he replaced his other medication with magnesium, and now his blood pressure is normal, and the arrhythmia has ceased. I hope this effect lasts!
Read More
9
Prevents hypertension flare-ups
I use various forms of magnesium, and this one definitely works. It helps keep my hypertension from flaring up. I highly recommend it.
Read More

Frequently Asked Questions

7.5
Calms irritability
2 people found this helpful
During my pregnancy, I became terribly irritable. I started taking magnesium to calm my nerves, and within a week, I felt much less irritable. I take 2 capsules twice a day, and my anger has lessened. Additionally, my doctor recommended magnesium for hypertension, and it has boosted my energy and alleviated leg cramps.
10
Normalizes blood pressure
1 people found this helpful
My husband has hypertension and started taking this magnesium every morning for the past few months. With the doctor’s advice, he replaced his other medication with magnesium, and now his blood pressure is normal, and the arrhythmia has ceased. I hope this effect lasts!
10
Reduces blood pressure
2 people found this helpful
BEST EVER MAG! I tried other brands and different forms with no effect on my hypertension, but after taking this magnesium, my blood pressure became normal. It's highly recommended. I'm on my third bottle already. AWESOME!
9
Supports cardiovascular health
Highly recommend for daily use! Magnesium in an easily digestible, chelated form is crucial as it exists in all body tissues and aids in metabolic processes. It's essential for those with cardiovascular disease, stress, convulsions, elevated blood pressure, or a sluggish gallbladder. In treating hypertension and cardiovascular ailments, consider adding coenzyme and Omega-3.
8
Magnesium effectively lowers blood pressure
We explored how magnesium supplementation can affect systolic blood pressure (SBP) in the general population. Through careful analysis of placebo-controlled, randomized clinical trials, we focused on understanding the optimal dosages and treatment durations necessary to achieve significant reductions in SBP. Past findings revealed that magnesium could reduce SBP by an average of 2.79 mm Hg, and our goal was to dive deeper into these results.

Our meta-analysis showed promising outcomes. Specifically, we noticed that magnesium taken at lower doses, particularly ≤360 mg per day, led to a notable decrease in SBP of about 3.03 mm Hg, especially when the treatment duration exceeded three months. This suggests that for those looking to manage their blood pressure, longer-term use of magnesium at these dosages may be beneficial.

While we found encouraging evidence pointing to the effectiveness of magnesium in lowering SBP, we acknowledge the importance of further studies. These future investigations should focus on varied dosages and longer follow-up periods to strengthen our understanding and provide tailored recommendations for individuals seeking to utilize magnesium in their hypertension management strategies.
9
Magnesium intake linked to reduced hypertension
We explored the connection between dietary magnesium intake and hypertension along with other health issues in US adults. In our study, we analyzed data from over 24,000 people, taking into account various lifestyle factors.

We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.

These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns.
7
Magnesium intake supports hypertension management
We conducted a randomized clinical trial to explore the effects of magnesium from deep ocean sources on adults dealing with hypertension, diabetes, or high cholesterol. Patients participated by consuming either magnesium-enriched water or a placebo over a four-week period.

Throughout the trial, we focused on key health indicators, including body mass index (BMI) and levels of insulin and triglycerides, among others. Our findings indicated that, despite some participants consuming less magnesium than the recommended daily allowance, those who drank magnesium-enriched water showed meaningful improvements in various metabolic markers.

Notably, we found that this water not only supported better metabolic outcomes but also positively influenced gut microbiome diversity. The magnesium-enriched water helped maintain a balanced abundance of beneficial gut bacteria, which is crucial for overall health. This indicates that boosting our magnesium intake, through sources like deep ocean water, might play a valuable role in controlling hypertension and possibly preventing related conditions without any significant adverse effects.

References

  1. Kang H, Lee UJ, Park BY, Kim M, Yang M. Effects of deep ocean-derived magnesium-enhanced water on metabolic diseases with microbiome changes. Diabetes Metab Syndr. 2025;19:103203. doi:10.1016/j.dsx.2025.103203
  2. Liu Y, Li W, Sun Y, Wang Z. Effects of magnesium sulfate combined with labetalol on vascular endothelial function and pregnancy outcomes in pregnant women with preeclampsia. Am J Transl Res. 2024;16:7096. doi:10.62347/COZZ1407
  3. Behers BJ, Behers BM, Stephenson-Moe CA, Vargas IA, Meng Z, et al. Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length. Nutrients. 2024;16. doi:10.3390/nu16213617
  4. Hojda SE, Chis IC, Mîrza TV, Clichici S. Monocrotaline-induced pulmonary arterial hypertension: the benefic effects of magnesium sulfate, Rosuvastatin and Sildenafil. Med Pharm Rep. 2024;97:528. doi:10.15386/mpr-2804
  5. Gong Y, Zhou C, Wan Y, Yin H. Association of magnesium deficiency, tobacco smoke exposure and hypertension in children and adolescents: evidence from the NHANES 2007-2018. BMC Pediatr. 2024;24:647. doi:10.1186/s12887-024-05097-z
  6. Amer SA, Abo-Elnour DE, Abbas A, Abdelrahman AS, Hamdy HM, et al. Calcium, magnesium, and vitamin D supplementations as complementary therapy for hypertensive patients: a systematic review and meta-analysis. BMC Complement Med Ther. 2025;25:89. doi:10.1186/s12906-025-04809-x
  7. Dariy V, Serikov K, Kmyta O, Rybalko T, Kolesnyk O. PERSONIFICATION OF ANTIHYPERTENSIVE THERAPY IN ISCHEMIC CEREBRAL STROKE. Georgian Med News. 2024.
  8. Song J, Zhang Y, Lin Z, Tang J, Yang X, et al. Higher Magnesium Depletion Score Increases the Risk of All-cause and Cardiovascular Mortality in Hypertension Participants. Biol Trace Elem Res. 2025;203:1287. doi:10.1007/s12011-024-04254-w
  9. Minor KC, Liu J, Druzin ML, El-Sayed YY, Hintz SR, et al. Magnesium sulfate and risk of hypoxic-ischemic encephalopathy in a high-risk cohort. Am J Obstet Gynecol. 2024;231:647.e1. doi:10.1016/j.ajog.2024.04.001
  10. Wang Q, Si K, Xing X, Ye X, Liu Z, et al. Association between dietary magnesium intake and muscle mass among hypertensive population: evidence from the National Health and Nutrition Examination Survey. Nutr J. 2024;23:37. doi:10.1186/s12937-024-00940-6
  11. Yerubandi S, Devi Kallur S, Gala A, Chandra Ravula P, Surapaneni T, et al. Eclampsia reduction with maternal early warning trigger tool. Pregnancy Hypertens. 2024;35:6. doi:10.1016/j.preghy.2023.11.007
  12. Peng Z, Zhang J, Xiao Y, Dong W. Comparison of outcomes following intravenous magnesium compared with intravenous labetalol and oral nifedipine in 355 pregnant Han Chinese women with preeclampsia. Medicine (Baltimore). 2023;102:e35334. doi:10.1097/MD.0000000000035334
  13. Su HC, Lin CP, Ho WJ, Chou SH, Wu CT, et al. Factors affecting the intensity of chronic musculoskeletal pain in patients with cardiovascular disease and evaluation of the efficacy of magnesium emulsion cream for muscle cramps. Medicine (Baltimore). 2023;102:e35532. doi:10.1097/MD.0000000000035532
  14. Vongpatanasin W, Giacona JM, Pittman D, Murillo A, Khan G, et al. Potassium Magnesium Citrate Is Superior to Potassium Chloride in Reversing Metabolic Side Effects of Chlorthalidone. Hypertension. 2023;80:2611. doi:10.1161/HYPERTENSIONAHA.123.21932
  15. Behers BJ, Melchor J, Behers BM, Meng Z, Swanson PJ, et al. Vitamins and Minerals for Blood Pressure Reduction in the General, Normotensive Population: A Systematic Review and Meta-Analysis of Six Supplements. Nutrients. 2023;15. doi:10.3390/nu15194223
  16. Han M, Zhang Y, Fang J, Sun M, Liu Q, et al. Associations between dietary magnesium intake and hypertension, diabetes, and hyperlipidemia. Hypertens Res. 2024;47:331. doi:10.1038/s41440-023-01439-z
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