Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
USERS' SCORE
Good
Based on 10 Reviews
8.2
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Magnesium (from 2,000 mg magnesium lysinate glycinate chelate) (Albion®)
200 mg
48%
Top Medical Research Studies
8
Magnesium shows potential benefits
We conducted a randomized double-blind study to see how supplementation with zinc, magnesium, and vitamin A might affect hypothyroidism.
In our trial with 86 participants, those receiving the supplements showed improved thyroid function, indicated by a significant increase in serum FT4 levels.
However, no noteworthy changes were observed in the control group regarding thyroid hormones.
Overall, while the supplementation shows promise for some thyroid improvement, it's not a guaranteed solution for everyone.
In our trial with 86 participants, those receiving the supplements showed improved thyroid function, indicated by a significant increase in serum FT4 levels.
However, no noteworthy changes were observed in the control group regarding thyroid hormones.
Overall, while the supplementation shows promise for some thyroid improvement, it's not a guaranteed solution for everyone.
Read More
4
Magnesium shows promise in thyroid recovery
We set out to investigate how magnesium, along with selenium and coenzyme Q10, could influence hypothyroidism in patients with benign thyroid diseases. Our approach included a small group of eight patients—five with hyperthyroidism and three with hypothyroidism—who received additional treatment aimed at addressing both their thyroid condition and related physical and psychological stresses.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
Read More
9
We explored the interaction between magnesium sulfate and levothyroxine in managing inflammation related to hypothyroidism. In this study, we used 60 male rats, dividing them into six different groups. These included normals, those given magnesium, hypothyroid rats, and various combinations of treatments with levothyroxine and magnesium.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Read More
Most Useful Reviews
9
Calmness and relief
5 people found this helpful
This product genuinely works well for my nervous system. After taking this magnesium alongside B vitamins, I achieved almost complete calmness. Caution is necessary to avoid overdosing, which can lead to lowered blood pressure; for me, it notably improved my stool regularity, a common issue with hypothyroidism. Although I experienced constipation previously, I needed to control my intake and had to stop after two weeks due to an accidental overdose. Nevertheless, I am pleased with the results and plan to order more.
Read More
9
Less muscle pain
Managing hypothyroidism, I've taken magnesium for three months and have noticed reduced muscle and joint pain. It's remarkable how I’ve forgotten about cramps entirely. My stomach function has improved, and my headaches have stopped, which is significant for my overall health.
Read More
9
Significant symptom relief
My endocrinologist prescribed magnesium, and after two weeks, I noticed significant improvements: better sleep, reduced numbness in my fingers at night, decreased headaches, and even my constant arrhythmia subsided. Living with hypothyroidism has been challenging for the past three years, but I aim to continue using this supplement as it appears essential for managing my cardiovascular health and emotional stability.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
- All Researches
9
We explored the interaction between magnesium sulfate and levothyroxine in managing inflammation related to hypothyroidism. In this study, we used 60 male rats, dividing them into six different groups. These included normals, those given magnesium, hypothyroid rats, and various combinations of treatments with levothyroxine and magnesium.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Read More
8
Magnesium shows potential benefits
We conducted a randomized double-blind study to see how supplementation with zinc, magnesium, and vitamin A might affect hypothyroidism.
In our trial with 86 participants, those receiving the supplements showed improved thyroid function, indicated by a significant increase in serum FT4 levels.
However, no noteworthy changes were observed in the control group regarding thyroid hormones.
Overall, while the supplementation shows promise for some thyroid improvement, it's not a guaranteed solution for everyone.
In our trial with 86 participants, those receiving the supplements showed improved thyroid function, indicated by a significant increase in serum FT4 levels.
However, no noteworthy changes were observed in the control group regarding thyroid hormones.
Overall, while the supplementation shows promise for some thyroid improvement, it's not a guaranteed solution for everyone.
Read More
We explored how magnesium, as part of a broader supplementation strategy, influences thyroid function and overall well-being in patients with hypothyroidism. In a well-structured study, 104 individuals receiving traditional treatment with levothyroxine and vitamin D were randomly divided into two groups. One group received a combination of essential micronutrients, including magnesium, while the other received placebos over an 8-week period.
Our observations highlighted changes in insulin resistance and quality of life after the intervention, suggesting that micronutrient supplementation could have a bearing on these aspects of health. However, the specifics regarding magnesium's isolated effect on thyroid function were less clear due to the multi-nutritional approach taken in this trial.
While we acknowledge promising results related to quality of life, we must clarify that the study does not provide concrete evidence that magnesium alone significantly improves thyroid function. Further, more focused clinical trials are necessary to ascertain the role of magnesium, allowing for a better understanding of its potential benefits in hypothyroid patients.
Our observations highlighted changes in insulin resistance and quality of life after the intervention, suggesting that micronutrient supplementation could have a bearing on these aspects of health. However, the specifics regarding magnesium's isolated effect on thyroid function were less clear due to the multi-nutritional approach taken in this trial.
While we acknowledge promising results related to quality of life, we must clarify that the study does not provide concrete evidence that magnesium alone significantly improves thyroid function. Further, more focused clinical trials are necessary to ascertain the role of magnesium, allowing for a better understanding of its potential benefits in hypothyroid patients.
Read More
7
Minerals affect thyroid dysfunction risk
We delved into how different minerals might influence thyroid dysfunction, particularly focusing on hypothyroidism. Analyzing data from nearly 7,800 people, we utilized advanced statistical methods to explore the impact of mineral intake on thyroid hormones.
While we found that higher intakes of minerals like magnesium and calcium were linked to lower rates of hyperthyroidism, the study did not show significant benefits of magnesium specifically for hypothyroidism. The results suggest that a balanced intake of various minerals may support thyroid health overall.
While we found that higher intakes of minerals like magnesium and calcium were linked to lower rates of hyperthyroidism, the study did not show significant benefits of magnesium specifically for hypothyroidism. The results suggest that a balanced intake of various minerals may support thyroid health overall.
Read More
4
Magnesium shows promise in thyroid recovery
We set out to investigate how magnesium, along with selenium and coenzyme Q10, could influence hypothyroidism in patients with benign thyroid diseases. Our approach included a small group of eight patients—five with hyperthyroidism and three with hypothyroidism—who received additional treatment aimed at addressing both their thyroid condition and related physical and psychological stresses.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
Read More
User Reviews
USERS' SCORE
Good
Based on 10 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Calmness and relief
5 people found this helpful
This product genuinely works well for my nervous system. After taking this magnesium alongside B vitamins, I achieved almost complete calmness. Caution is necessary to avoid overdosing, which can lead to lowered blood pressure; for me, it notably improved my stool regularity, a common issue with hypothyroidism. Although I experienced constipation previously, I needed to control my intake and had to stop after two weeks due to an accidental overdose. Nevertheless, I am pleased with the results and plan to order more.
Read More
9
Less muscle pain
Managing hypothyroidism, I've taken magnesium for three months and have noticed reduced muscle and joint pain. It's remarkable how I’ve forgotten about cramps entirely. My stomach function has improved, and my headaches have stopped, which is significant for my overall health.
Read More
9
Significant symptom relief
My endocrinologist prescribed magnesium, and after two weeks, I noticed significant improvements: better sleep, reduced numbness in my fingers at night, decreased headaches, and even my constant arrhythmia subsided. Living with hypothyroidism has been challenging for the past three years, but I aim to continue using this supplement as it appears essential for managing my cardiovascular health and emotional stability.
Read More
7.5
Reduced swelling
11 people found this helpful
Since being diagnosed with hypothyroidism, I have endured significant edema, with swelling affecting my face and legs. Since starting magnesium, I've noticed a reduction in swelling, which seems apparent to others as well. After three months of consistent use, I plan to continue ordering it.
Read More
7.5
Improved sleep quality
9 people found this helpful
Having tried various magnesium preparations, I believe this product is the best for me. Taking 3-4 pills daily, I can be sensitive to different forms; citrate magnesium caused discomfort. This chelated magnesium is a true relief, promoting relaxation before bedtime and enhancing my sleep quality. As someone living with autonomic instability and hypothyroidism, quality sleep is vital for my wellbeing. Long-term magnesium intake may lower blood pressure, so dosage should be based on how I feel. Although some reviews mention the pill's size, I find it manageable. I can't imagine life without this mineral; it has become a staple for me. I highly recommend it for health and restful sleep!
Read More
Frequently Asked Questions
9
Enhanced wellbeing
1 people found this helpful
This magnesium is wonderfully digestible, and I regularly take between 100 to 400 mg. My sleep quality has notably improved, and I no longer suffer from cramps or numbness in my legs. As someone with hypothyroidism, magnesium is crucial for my health, and I have genuinely felt better since incorporating it into my routine.
7.5
Essential supplement
With autoimmune thyroiditis and hypothyroidism, I find magnesium vital for my thyroid function since it aids in converting inactive T4 hormone into active T3. I take 400 mg at night and have seen cramps vanish, along with a marked sense of calm. Regular use is manageable, with breaks once a year necessary.
6
Muscle twitching issue
I initially took this magnesium for stronger nerves and better sleep, vital for my hypothyroidism and Hashimoto's. After a while on two pills daily, I felt improvements in my sleep and mood. However, I began experiencing muscle twitching in my face as I progressed through the jar. I reduced my dosage to one tablet per day, which lessened the twitching. When I stopped taking it for a few days, the twitching completely ceased. Unfortunately, I couldn't finish the supplement due to the increased intensity of the twitching. I can't explain why this happened, but I may try another brand.
We explored how magnesium, as part of a broader supplementation strategy, influences thyroid function and overall well-being in patients with hypothyroidism. In a well-structured study, 104 individuals receiving traditional treatment with levothyroxine and vitamin D were randomly divided into two groups. One group received a combination of essential micronutrients, including magnesium, while the other received placebos over an 8-week period.
Our observations highlighted changes in insulin resistance and quality of life after the intervention, suggesting that micronutrient supplementation could have a bearing on these aspects of health. However, the specifics regarding magnesium's isolated effect on thyroid function were less clear due to the multi-nutritional approach taken in this trial.
While we acknowledge promising results related to quality of life, we must clarify that the study does not provide concrete evidence that magnesium alone significantly improves thyroid function. Further, more focused clinical trials are necessary to ascertain the role of magnesium, allowing for a better understanding of its potential benefits in hypothyroid patients.
Our observations highlighted changes in insulin resistance and quality of life after the intervention, suggesting that micronutrient supplementation could have a bearing on these aspects of health. However, the specifics regarding magnesium's isolated effect on thyroid function were less clear due to the multi-nutritional approach taken in this trial.
While we acknowledge promising results related to quality of life, we must clarify that the study does not provide concrete evidence that magnesium alone significantly improves thyroid function. Further, more focused clinical trials are necessary to ascertain the role of magnesium, allowing for a better understanding of its potential benefits in hypothyroid patients.
9
We explored the interaction between magnesium sulfate and levothyroxine in managing inflammation related to hypothyroidism. In this study, we used 60 male rats, dividing them into six different groups. These included normals, those given magnesium, hypothyroid rats, and various combinations of treatments with levothyroxine and magnesium.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
7
Minerals affect thyroid dysfunction risk
We delved into how different minerals might influence thyroid dysfunction, particularly focusing on hypothyroidism. Analyzing data from nearly 7,800 people, we utilized advanced statistical methods to explore the impact of mineral intake on thyroid hormones.
While we found that higher intakes of minerals like magnesium and calcium were linked to lower rates of hyperthyroidism, the study did not show significant benefits of magnesium specifically for hypothyroidism. The results suggest that a balanced intake of various minerals may support thyroid health overall.
While we found that higher intakes of minerals like magnesium and calcium were linked to lower rates of hyperthyroidism, the study did not show significant benefits of magnesium specifically for hypothyroidism. The results suggest that a balanced intake of various minerals may support thyroid health overall.
8
Magnesium shows potential benefits
We conducted a randomized double-blind study to see how supplementation with zinc, magnesium, and vitamin A might affect hypothyroidism.
In our trial with 86 participants, those receiving the supplements showed improved thyroid function, indicated by a significant increase in serum FT4 levels.
However, no noteworthy changes were observed in the control group regarding thyroid hormones.
Overall, while the supplementation shows promise for some thyroid improvement, it's not a guaranteed solution for everyone.
In our trial with 86 participants, those receiving the supplements showed improved thyroid function, indicated by a significant increase in serum FT4 levels.
However, no noteworthy changes were observed in the control group regarding thyroid hormones.
Overall, while the supplementation shows promise for some thyroid improvement, it's not a guaranteed solution for everyone.
References
- Nikkhah M, Vafa M, Abiri B, Golgiri F, Sarbakhsh P, et al. The Effect of Some Micronutrients Multi-Supplementation on Thyroid Function, Metabolic Features and Quality of Life in Patients Treating With Levothyroxine and Vitamin D: A Double-blind, Randomized Controlled Trial. Med J Islam Repub Iran. 2024;38:133. doi:10.47176/mjiri.38.133
- Abbas AM, Sakr HF. Effect of magnesium sulfate and thyroxine on inflammatory markers in a rat model of hypothyroidism. Can J Physiol Pharmacol. 2016;94:426. doi:10.1139/cjpp-2015-0247
- Moncayo R, Moncayo H. Proof of concept of the WOMED model of benign thyroid disease: Restitution of thyroid morphology after correction of physical and psychological stressors and magnesium supplementation. BBA Clin. 2015;3:113. doi:10.1016/j.bbacli.2014.12.005
- Liu S, Huang W, Lin Y, Wang Y, Li H, et al. Machine learning-based exploration of the associations between multiple minerals' intake and thyroid dysfunction: data from the National Health and Nutrition Examination Survey. Front Nutr. 2025;12:1522232. doi:10.3389/fnut.2025.1522232
- Rabbani E, Golgiri F, Janani L, Moradi N, Fallah S, et al. Randomized Study of the Effects of Zinc, Vitamin A, and Magnesium Co-supplementation on Thyroid Function, Oxidative Stress, and hs-CRP in Patients with Hypothyroidism. Biol Trace Elem Res. 2021;199:4074. doi:10.1007/s12011-020-02548-3
