We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
4
Magnesium shows limited sleep benefits
Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis.
We explored the effects of magnesium supplementation on insomnia in older adults through a systematic review and meta-analysis. Our investigation included several studies that compared magnesium with a placebo or no treatment.
We found three randomized control trials involving 151 older adults across three countries. The pooled results indicated that individuals taking magnesium had a notable decrease in sleep onset latency, averaging a reduction of 17.36 minutes compared to those on placebo. However, the improvement in total sleep time, which increased by 16.06 minutes in the magnesium group, did not reach statistical significance.
Despite these findings, we must emphasize that the overall quality of the research is below standards necessary for making firm recommendations. All studies reviewed showed a moderate to high risk of bias, and the evidence quality ranged from low to very low. Nonetheless, magnesium is an affordable and widely accessible option for those struggling with insomnia symptoms, suggesting it may be a reasonable consideration for some older adults.
Read More
8
Magnesium may reduce daytime sleepiness
Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up.
We set out to explore how dietary magnesium might impact symptoms of insomnia, such as falling asleep during the day and snoring at night. Our study included a significant sample of 1,487 adults from the Jiangsu Nutrition Study, which allowed us to gather valuable information about their magnesium intake and sleep experiences. Over five years, we assessed participants' magnesium consumption through detailed food records and later examined their sleep patterns via a questionnaire.
Our findings revealed that the average magnesium intake among participants was 332.5 mg per day. Interestingly, we found that around 5.3% reported falling asleep during the day, 13.2% faced daytime sleepiness, and 35.7% experienced snoring at night. Rising through the quartiles of magnesium intake, we observed a promising decrease in the chance of women experiencing daytime falling asleep; however, this effect wasn’t mirrored in men. It’s crucial to note that we didn’t find significant associations between magnesium intake and daytime sleepiness or night snoring for either gender.
Overall, it seems that dietary magnesium might offer long-term benefits in reducing daytime sleepiness in women, while more research could clarify its effects on other symptoms. This makes magnesium an interesting dietary consideration for those seeking to improve their sleep quality.
Read More
Most Useful Reviews
9
Restored sound sleep
346 people found this helpful
I loved this chelated form of magnesium! It does not cause gastrointestinal upset, which is important to me. It helped restore my sound sleep, alleviating my insomnia. I noticed a calmer reaction to stimuli. Periodically changing magnesium forms has been beneficial, as I had cramps in my legs. Since using this magnesium, I’ve forgotten about those issues. I felt a surge of vitality, and I wish the same for you!
Read More
9
Alleviated insomnia issues
210 people found this helpful
I really liked this chelated magnesium! It doesn't cause gastrointestinal upset, which is important to me. It helped restore my sound sleep after suffering from insomnia for long periods. I also experienced cramps in my legs, but since taking this magnesium, those issues have disappeared. I'm very satisfied with this product.
Read More
9
Great for insomnia
153 people found this helpful
I had significant sleep problems. I struggled to fall asleep and often woke up in the middle of the night. After following my doctor’s advice, I tried these vitamins. They effectively helped me overcome insomnia, relaxed my muscles, and reduced my anxiety.
We explored the potential benefits of a supplement containing magnesium, melatonin, and vitamin B complex in treating insomnia. The study involved 60 patients diagnosed with insomnia, who were divided into a study group and a control group. Over three months, the study group received a daily dose of the supplement, while the control group did not receive it.
At the start, both groups had similar levels of insomnia, indicated by their scores on the Athens insomnia scale. However, after three months of supplementation, the study group showed a significant improvement, with their insomnia scores decreasing, indicating mild insomnia. In contrast, the control group’s scores remained stable, suggesting they continued to experience moderate insomnia.
Although magnesium was part of the supplement, the study design makes it challenging to isolate its specific effects on insomnia. Nevertheless, we observed that combining magnesium with melatonin and vitamin B complex potentially enhances sleep quality for those struggling with insomnia.
Read More
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
9
Magnesium may aid sleep quality
The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial in a long-term care facility in Italy to explore whether nightly doses of melatonin, magnesium, and zinc could benefit residents suffering from primary insomnia. Our study involved 43 participants, who were either given a combined supplement of these nutrients or a placebo for eight weeks.
The primary objective was to measure sleep quality using the Pittsburgh Sleep Quality Index, while we also considered secondary indicators like daytime sleepiness and overall quality of life. The results revealed that the combined approach of melatonin, magnesium, and zinc appeared to improve both sleep and quality of life for residents struggling with insomnia.
However, since magnesium was tested alongside two other supplements, we cannot clearly attribute the benefits directly to magnesium alone. Overall, the findings suggest a positive effect on sleep quality and well-being for long-term care residents dealing with insomnia, but we must be cautious in isolating each nutrient's individual effectiveness.
Read More
8
Magnesium improves insomnia in diabetes
Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
We conducted a randomized controlled trial focusing on individuals with diabetes who struggle with insomnia. Over two months, we examined the effects of magnesium and potassium supplementation on sleep quality and hormone levels. Our study included 320 patients, and after follow-up, 290 patients completed the trial. We assessed insomnia severity using the Insomnia Severity Index and analyzed changes in melatonin and cortisol levels, which are key sleep hormones.
Our findings indicated that magnesium supplementation—whether alone or in combination with potassium—had a notable positive impact. Participants who received magnesium and potassium demonstrated significant improvements in both insomnia severity and sleep hormone levels. It was exciting to see how these supplements could enhance sleep duration and quality in those facing the dual challenges of insomnia and diabetes.
Although the combination of magnesium and potassium was effective, we recognize that this limits a clear assessment of magnesium's isolated effects. Nevertheless, our research adds valuable insights on how these minerals may play a role in managing insomnia among diabetic patients.
Read More
8
Magnesium may aid post-surgery insomnia
Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial.
We conducted a study to explore how magnesium affects insomnia in patients undergoing lumbar fixation surgery. Our research involved 80 participants, divided into two groups: one received conventional general anesthesia supplemented with magnesium sulfate, while the other had standard anesthesia without magnesium.
We assessed various factors, including insomnia severity using the Insomnia Severity Index and post-operative delirium through the Memorial Delirium Assessment Scale. Interestingly, our findings indicated a significant relationship between the administration of magnesium and reduced instances of post-operative insomnia.
This suggests that magnesium may be beneficial in easing sleep disturbances experienced by some patients after surgery. However, we also noted variations due to other factors like pain and depression, which could influence the overall results.
While the relationship is promising, it’s essential to recognize that there may be multiple factors at play that contribute to insomnia post-surgery. Overall, our evaluation presents magnesium as a potentially helpful option for enhancing sleep quality in these patients.
I loved this chelated form of magnesium! It does not cause gastrointestinal upset, which is important to me. It helped restore my sound sleep, alleviating my insomnia. I noticed a calmer reaction to stimuli. Periodically changing magnesium forms has been beneficial, as I had cramps in my legs. Since using this magnesium, I’ve forgotten about those issues. I felt a surge of vitality, and I wish the same for you!
Read More
9
Alleviated insomnia issues
210 people found this helpful
I really liked this chelated magnesium! It doesn't cause gastrointestinal upset, which is important to me. It helped restore my sound sleep after suffering from insomnia for long periods. I also experienced cramps in my legs, but since taking this magnesium, those issues have disappeared. I'm very satisfied with this product.
Read More
9
Great for insomnia
153 people found this helpful
I had significant sleep problems. I struggled to fall asleep and often woke up in the middle of the night. After following my doctor’s advice, I tried these vitamins. They effectively helped me overcome insomnia, relaxed my muscles, and reduced my anxiety.
Read More
9
Improved sleep quality
135 people found this helpful
My sleep was poor, struggling for hours to fall asleep. Since using these pills from day one, I found myself relaxing and drifting off within an hour. After extended use, I feel revitalised. It’s helped with insomnia, stress, and fatigue. I’ll provide a further update after a month and a half of use.
Read More
10
Effective sleep aid
67 people found this helpful
This product has been the most effective sleep aid I’ve ever used for my chronic insomnia.
Insomnia is a common sleep disorder characterized by the inability to fall asleep, stay asleep, or wake up too early and not be able to go back to sleep. Individuals experiencing insomnia may find that it affects their daytime functioning, leading to issues such as fatigue, mood disturbances, and difficulty concentrating. Insomnia can be classified into two main types: acute insomnia, which lasts for a short period often triggered by stress or life changes, and chronic insomnia, which occurs at least three times a week for three months or longer, and may require more in-depth evaluation and treatment.
Numerous factors can contribute to insomnia, including stress, anxiety, poor sleep habits, medical conditions, and the use of certain medications. Treatment for insomnia typically involves a combination of lifestyle changes, cognitive behavioral therapy for insomnia (CBT-I), and sometimes medication. Establishing a consistent sleep routine, creating a comfortable sleep environment, and practicing relaxation techniques can help improve sleep quality. If insomnia persists, it is advisable to consult a healthcare professional for proper diagnosis and customized treatment options.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium is often touted as a natural remedy for improving sleep quality and managing insomnia. This essential mineral plays a crucial role in various bodily functions, including the regulation of neurotransmitters that send signals throughout the nervous system and brain. Some studies suggest that magnesium may assist in promoting relaxation by helping to regulate melatonin, a hormone responsible for sleep-wake cycles. Additionally, it may help reduce anxiety and stress, which are common culprits of sleep disturbances.
While many people report improved sleep after incorporating magnesium supplements or magnesium-rich foods—like leafy greens, nuts, and whole grains—into their diets, the scientific evidence is mixed. More research is needed to definitively establish its effectiveness in treating insomnia. If you're considering magnesium supplements, it's always best to consult with a healthcare professional to determine the appropriate dosage and ensure that it won’t interact with any medications you may be taking. Overall, while magnesium may offer some benefits for sleep, it is most effective when used as part of a comprehensive approach to improving sleep hygiene.
Based on user reviews, the time it typically takes to see results from this magnesium supplement for insomnia varies among individuals. Many users report improvements within days, with some noting they experienced better sleep on the very first day of taking the supplement Read Review. Others have indicated noticeable effects in as little as two weeks Read Review or 18 days, with ongoing benefits growing stronger over that period Read Review.
Users have highlighted that consistent usage can lead to significant and lasting improvements. For instance, one individual reported their sleep issues were resolved effectively after only three days Read Review. Overall, while initial results can be felt quickly, many also mention continued benefits over weeks of regular use. Therefore, if you're considering this supplement for insomnia, you may start to see noticeable effects within the first few days to a couple of weeks.
The evidence surrounding magnesium as a potential remedy for insomnia shows promise, but it's not without its caveats. Several studies have indicated that magnesium supplementation can improve sleep quality. For instance, a randomized controlled trial involving 46 older adults showed significant improvements in sleep efficiency and insomnia severity among those who received magnesium after eight weeks [8]. In another study focusing on diabetic patients, magnesium combined with potassium led to notable enhancements in sleep duration and quality [1]. However, it's crucial to understand that not all research unanimously supports magnesium; some studies presented mixed results, highlighting the variance in dosage and participant demographics [3].
Despite the potential benefits, the overall quality of research remains inconsistent, with many studies displaying moderate to high bias risk [4]. Consequently, while magnesium may be an accessible option for managing insomnia, particularly in certain populations such as older adults and those with specific medical conditions, the need for more robust, large-scale trials is clear. Hence, if you're considering magnesium as a supplement for insomnia, it may be worthwhile, but speak with a healthcare provider to determine the best approach for your individual situation.
Users have reported a range of improvements in their insomnia symptoms after using this magnesium supplement. Many individuals, like the person who struggled with chronic pain and insomnia, noted a significant reduction in their sleep difficulties, experiencing a peaceful night’s sleep for the first time in years Read Review. Others highlighted a quicker onset of sleep and reduced awakenings at night, with one review mentioning falling asleep within 20 minutes and waking up feeling refreshed Read Review. Users have also reported that the supplement helped alleviate associated symptoms such as anxiety and cramps, allowing for a more restorative sleep experience overall Read Review.
Additionally, several reviewers commented on the ease of incorporation into their routines, with many finding the capsules easy to swallow and reporting no gastrointestinal discomfort, which is often a concern with magnesium products Read Review. While individual results can vary, as seen in the differing experiences of users, the overall trend indicates that a considerable number have found this magnesium supplement to be effective in addressing their insomnia and enhancing their sleep quality.
Users have reported positive experiences when combining this magnesium supplement with other vitamins and supplements to effectively manage insomnia. Many have found that while the magnesium alone has provided substantial relief from their sleep difficulties, the addition of other supplements seems to amplify the benefits. For instance, one user noted that taking magnesium alongside complex vitamins yielded maximum effect in improving their sleep quality Read Review. Similarly, another reviewer mentioned that combining magnesium with additional vitamins helped in substantially enhancing their overall sleep experience Read Review.
Additionally, users have emphasized that the flexibility in incorporating this magnesium supplement into their nighttime routines allows them to tailor their sleep aids to their specific needs. One individual stated that they take four tablets of magnesium before bed, in conjunction with other supplements, which has effectively replaced their reliance on prescription medications like benzodiazepines Read Review. Overall, the consensus among users appears to be that combining this magnesium with other supportive supplements can help achieve an even more significant impact on managing insomnia.
Based on user reviews, there is a mix of experiences regarding the optimal dosage of magnesium for alleviating insomnia. Some users report that taking one to two tablets before bed effectively improves their sleep quality and helps them fall asleep faster. For instance, one reviewer noted that taking two tablets helped them drift off within an hour and wake up feeling revitalized Read Review. Similarly, another user mentioned taking three tablets daily led to a significant relief from both headaches and insomnia Read Review.
Conversely, some users require higher dosages for similar benefits, with one reviewer indicating that four tablets taken each night are necessary for effective results in managing their chronic insomnia Read Review. This suggests that individual responses to magnesium supplementation vary, and factors like the type of magnesium, personal health conditions, and tolerance may influence the ideal amount. Overall, while lower doses seem effective for some, others find success with higher quantities, underscoring the importance of personalized dosage adjustments.
9
Improved sleep quality
135 people found this helpful
My sleep was poor, struggling for hours to fall asleep. Since using these pills from day one, I found myself relaxing and drifting off within an hour. After extended use, I feel revitalised. It’s helped with insomnia, stress, and fatigue. I’ll provide a further update after a month and a half of use.
9
Ailments resolved
20 people found this helpful
I realised I was likely magnesium deficient due to insomnia and cramps. Since taking Doctor's Best chelated magnesium, my issues have subsided within two weeks. My mother now uses it as well for her insomnia. This product is truly beneficial!
9
Reduced insomnia effectively
61 people found this helpful
I bought this for my grandma, who suffers from severe pain and insomnia. It has allowed her to sleep without needing immobilizers and significantly reduced her insomnia. After just 18 days, I’ve even encouraged family members to try it, as it has made a noticeable difference.
9
Deep sleep restored
15 people found this helpful
I struggled with insomnia for months due to job stress. After learning about magnesium’s role in sleep, I began taking it. Remarkably, on the third day, I fell asleep within 20 minutes, achieving deep sleep and feeling refreshed in the morning. It's truly saved me!
10
Life-changing impact
9 people found this helpful
This magnesium has changed my life. After struggling with chronic pain and insomnia while on various medications, I found relief after taking this supplement. I've experienced a significant reduction in pain and improved sleep quality.
9
Alleviated insomnia issues
210 people found this helpful
I really liked this chelated magnesium! It doesn't cause gastrointestinal upset, which is important to me. It helped restore my sound sleep after suffering from insomnia for long periods. I also experienced cramps in my legs, but since taking this magnesium, those issues have disappeared. I'm very satisfied with this product.
9
Sleep cocktail success
29 people found this helpful
As a lifelong sufferer of insomnia, I incorporate this magnesium into my sleep regimen alongside other supplements. It requires taking four tablets before bed, but it’s effective for me. Though the tablets are large, they don’t bother me. This mix has worked better than my previous reliance on benzodiazepines.
9
Improved sleep
12 people found this helpful
At 46, I began having insomnia over the last few years. Magnesium has been a lifesaver for my sleep, allowing me to fall asleep quickly and wake up refreshed. I take it before bed along with complex vitamins for maximum effect.
9
Quality of life
11 people found this helpful
After significant weight loss, I experienced muscle weakness and insomnia. Since taking magnesium and other vitamins, my sleep quality has dramatically improved and my pain has diminished. I highly recommend this product.
9
Deep sleep achieved
42 people found this helpful
Wonderful Magnesium! After struggling with insomnia and cramps, I started taking this magnesium. It being 100% chelated and highly absorbable made a difference. Taking two tablets before bed helped me fall into a deep sleep and I woke up rejuvenated! My anxiety eased, and I no longer experience cramps. I’ll keep using it and recommend it to others.
7.5
Helped with headaches
47 people found this helpful
I suffered from headaches and insomnia despite taking painkillers. Switching to herbal medicine didn't help. However, after taking three tablets daily, I noticed significant relief from my headaches and insomnia. The pills are large but easy to swallow. This is worth trying for anyone battling similar issues!
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
8
Magnesium improves insomnia in diabetes
Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
We conducted a randomized controlled trial focusing on individuals with diabetes who struggle with insomnia. Over two months, we examined the effects of magnesium and potassium supplementation on sleep quality and hormone levels. Our study included 320 patients, and after follow-up, 290 patients completed the trial. We assessed insomnia severity using the Insomnia Severity Index and analyzed changes in melatonin and cortisol levels, which are key sleep hormones.
Our findings indicated that magnesium supplementation—whether alone or in combination with potassium—had a notable positive impact. Participants who received magnesium and potassium demonstrated significant improvements in both insomnia severity and sleep hormone levels. It was exciting to see how these supplements could enhance sleep duration and quality in those facing the dual challenges of insomnia and diabetes.
Although the combination of magnesium and potassium was effective, we recognize that this limits a clear assessment of magnesium's isolated effects. Nevertheless, our research adds valuable insights on how these minerals may play a role in managing insomnia among diabetic patients.
7
Magnesium may improve insomnia
Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.
We examined the potential benefits of magnesium supplements for improving sleep quality through a detailed analysis of existing clinical studies. Our systematic review focused specifically on trials investigating how magnesium affects insomnia, which have gained popularity among people seeking natural remedies for sleep problems.
A total of 15 relevant studies were reviewed. Among these, eight studies looked specifically at sleep-related outcomes, often employing the Pittsburgh Sleep Quality Index (PSQI) to measure improvements. The results were promising—five out of the eight studies indicated that magnesium supplementation led to better sleep quality.
However, it's important to note that not all studies observed benefits; two showed no significant improvements, and one provided mixed results. Many of these studies varied in the dosage, type of magnesium used, and overall participant numbers, which made it challenging to draw firm conclusions. Still, the general trend suggests that magnesium could indeed be helpful, especially for those who start with low magnesium levels.
Ultimately, while the findings lean towards positive, further large-scale, randomized trials are necessary to confirm the effectiveness of specific magnesium formulations and dosages in treating insomnia. We take these outcomes seriously, considering them a first step towards understanding how this mineral can help those struggling with sleep issues.
4
Magnesium shows limited sleep benefits
Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis.
We explored the effects of magnesium supplementation on insomnia in older adults through a systematic review and meta-analysis. Our investigation included several studies that compared magnesium with a placebo or no treatment.
We found three randomized control trials involving 151 older adults across three countries. The pooled results indicated that individuals taking magnesium had a notable decrease in sleep onset latency, averaging a reduction of 17.36 minutes compared to those on placebo. However, the improvement in total sleep time, which increased by 16.06 minutes in the magnesium group, did not reach statistical significance.
Despite these findings, we must emphasize that the overall quality of the research is below standards necessary for making firm recommendations. All studies reviewed showed a moderate to high risk of bias, and the evidence quality ranged from low to very low. Nonetheless, magnesium is an affordable and widely accessible option for those struggling with insomnia symptoms, suggesting it may be a reasonable consideration for some older adults.
References
Khalid S, Bashir S, Mehboob R, Anwar T, Ali M, et al. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus. Front Endocrinol (Lausanne). 2024;15:1370733. doi:10.3389/fendo.2024.1370733
Fathy W, Hussein M, Elanwar R, Elmoutaz H, Abdelsadek DA, et al. Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial. BMC Anesthesiol. 2024;24:289. doi:10.1186/s12871-024-02579-6
Rawji A, Peltier MR, Mourtzanakis K, Awan S, Rana J, et al. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review. Cureus. 2024;16:e59317. doi:10.7759/cureus.59317
Mah J, Pitre T. Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis. BMC Complement Med Ther. 2021;21:125. doi:10.1186/s12906-021-03297-z
Djokic G, Vojvodić P, Korcok D, Agic A, Rankovic A, et al. The Effects of Magnesium - Melatonin - Vit B Complex Supplementation in Treatment of Insomnia. Open Access Maced J Med Sci. 2019;7:3101. doi:10.3889/oamjms.2019.771
Cao Y, Zhen S, Taylor AW, Appleton S, Atlantis E, et al. Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up. Nutrients. 2018;10. doi:10.3390/nu10101354
Scholey A, Benson S, Gibbs A, Perry N, Sarris J, et al. Exploring the Effect of Lactium™ and Zizyphus Complex on Sleep Quality: A Double-Blind, Randomized Placebo-Controlled Trial. Nutrients. 2017;9. doi:10.3390/nu9020154
Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, et al. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17:1161.
Rondanelli M, Opizzi A, Monteferrario F, Antoniello N, Manni R, et al. The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial. J Am Geriatr Soc. 2011;59:82. doi:10.1111/j.1532-5415.2010.03232.x
Mucci M, Carraro C, Mancino P, Monti M, Papadia LS, et al. Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause. Minerva Ginecol. 2006;58:323.
Hornyak M, Haas P, Veit J, Gann H, Riemann D. Magnesium treatment of primary alcohol-dependent patients during subacute withdrawal: an open pilot study with polysomnography. Alcohol Clin Exp Res. 2004;28:1702.
Hornyak M, Voderholzer U, Hohagen F, Berger M, Riemann D. Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study. Sleep. 1998;21:501.