The Causal Role of Magnesium Deficiency in the Neuroinflammation, Pain Hypersensitivity and Memory/Emotional Deficits in Ovariectomized and Aged Female Mice.
We explored the connection between magnesium deficiency and various challenges commonly faced by postmenopausal women, such as chronic pain, memory decline, and mood disorders. Our research specifically focused on how magnesium supplementation can help in alleviating these issues in ovariectomized and aged female mice—modeling the postmenopausal state.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
Read More
7
Magnesium impacts menopause bone health
Magnesium Intake Predicts Bone Turnover in Postmenopausal Black South African Women.
We explored the relationship between magnesium intake and bone health in postmenopausal black South African women over a two-year period. In this study, which included 144 participants, researchers measured bone mineral density (BMD) at several key sites, alongside various biochemical analyses, including bone turnover markers.
The findings highlighted that higher dietary magnesium intake was linked to lower levels of C-Telopeptide of type I collagen (CTX-1), indicating reduced bone resorption. Moreover, calcium intake showed a positive correlation with BMD at the distal radius both at the start and end of the study.
Interestingly, one dietary pattern—snacking—also related to BMD scores over time, suggesting that what we eat can influence our bone health as we age. The results revealed that magnesium intake alone predicted a notable portion of the changes in bone turnover, emphasizing its potential role in supporting bone health during menopause.
Overall, this study suggests that paying attention to magnesium in our diets could be beneficial for women navigating menopause, especially regarding bone health.
Read More
7
Magnesium's limited effectiveness on menopause
The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a systematic review.
We reviewed various studies to understand how magnesium and other dietary supplements like B vitamins and essential fatty acids affect stress and anxiety in women. Our search included women aged 18 and older who had their stress levels assessed.
Although magnesium showed potential benefits, particularly in combination with vitamin B6 for premenstrual anxiety, the results overall suggested limited effectiveness in managing menopause-related anxiety when evaluated across all studies.
We found that essential fatty acids could help reduce stress during pregnancy and menopause, but more research is needed to establish more definitive findings.
Read More
Most Useful Reviews
9
Mood stabilisation noted
2 people found this helpful
I bought this for my mother during menopause. Good magnesium! It eliminates frequent hot flashes and normalises her mood, contributing to improved sleep and overall wellbeing.
Read More
9
Pain relief achieved
1 people found this helpful
It is essential right before my period. I take it when my uterus starts to contract, sometimes twice a day. I use it whenever I feel abdominal pain until bleeding occurs. Since entering menopause, I suffered from terrible menstrual pain and headaches, but this product has genuinely alleviated my suffering. I am incredibly grateful to live free from headache medication now.
Read More
9
Muscle tension relief
1 people found this helpful
The quality of this supplement surpassed my expectations. Its high-absorption magnesium ingredient effectively relieves muscle tension and significantly benefits sleep quality. It has also helped regulate hormones affected by menopause. It offers excellent value for money with a substantial number of capsules.
The Causal Role of Magnesium Deficiency in the Neuroinflammation, Pain Hypersensitivity and Memory/Emotional Deficits in Ovariectomized and Aged Female Mice.
We explored the connection between magnesium deficiency and various challenges commonly faced by postmenopausal women, such as chronic pain, memory decline, and mood disorders. Our research specifically focused on how magnesium supplementation can help in alleviating these issues in ovariectomized and aged female mice—modeling the postmenopausal state.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
Read More
9
Magnesium's impact on bone health
Supplementation of nanofiltrated deep ocean water ameliorate the progression of osteoporosis in ovariectomized rat via regulating osteoblast differentiation.
Our exploration centered on the effects of magnesium, particularly from nanofiltrated deep ocean water (DOW), in addressing osteoporosis, a common concern during menopause. In our study, we used ovariectomized female Sprague-Dawley rats, a model that simulates menopausal conditions. We administered varying amounts of DOW daily over eight weeks to observe its impact on bone health.
We found that DOW supplementation significantly increased bone density and reduced bone loss related to menopause. This was particularly notable as the rats that received DOW showed improved bone structure and reduced adiposity in their bones. More specifically, the lowest doses of DOW led to increased expression of a key protein called RUNX2, which plays an essential role in the formation of bone cells known as osteoblasts.
In human osteoblasts, DOW also raised levels of osteocalcin and alkaline phosphatase—both vital for promoting bone health. Overall, our findings demonstrated that magnesium-rich DOW can enhance osteoblast differentiation, contributing positively to bone structure integrity during menopause. This work highlights how incorporating magnesium into our diets or supplements could be beneficial for bone health as we age.
Read More
9
Isoflavones, probiotics boost bone health
Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial.
We explored the impact of a novel red clover extract rich in isoflavones and probiotics on bone health in postmenopausal osteopenic women. In a year-long double-blind trial with 78 participants, we compared this treatment alongside standard supplements against a placebo. Results showed that the extract substantially reduced bone mineral density loss and improved certain estrogen metabolism markers. However, it did not affect other bone turnover indicators significantly. Overall, combining the extract with calcium and magnesium proved beneficial for bone health in this demographic.
Read More
9
Magnesium reduces menopause symptoms
Effects of a new combination of nutraceuticals on postmenopausal symptoms and metabolic profile: a crossover, randomized, double-blind trial.
We explored the effects of a nutraceutical blend, including magnesium, on menopause symptoms through a crossover trial involving 43 postmenopausal women.
Participants experienced significant reductions in menopause symptoms, as measured by the Menopause Rating Scale, after using the nutraceuticals.
Additionally, improvements were noted in cardiovascular risk factors, such as lower cholesterol levels and blood pressure.
Overall, this study suggests that magnesium, combined with other nutrients, may provide meaningful relief for postmenopausal symptoms.
Read More
7
Magnesium aids menopausal metabolism
Utilizing a Combination of Supplements Comprising Boric Acid, Magnesium, Vitamin D3, and Extra Virgin Olive Oil to Improve Metabolism in Menopausal Ovariectomized Rats.
We conducted a study to understand how magnesium, along with other supplements, could influence metabolic health during menopause. Our research involved 42 adult female rats that were either ovariectomized or kept as controls. We divided them into seven groups to assess the effects of various treatments, including magnesium, boric acid, vitamin D3, extra virgin olive oil, and combinations of these supplements.
The results were promising. We observed significant improvements in markers related to inflammation, oxidative stress, and various metabolic parameters when magnesium was included in the treatment plans. Interestingly, the rats receiving magnesium, especially as part of a combined treatment, showed better results than those given individual supplements. This suggests that magnesium could play a valuable role in supporting metabolic health during menopause.
However, it’s worth noting that while magnesium demonstrated beneficial effects, the comprehensive impact of each supplement used individually wasn’t singled out for analysis. Thus, while magnesium appears to contribute positively, we cannot decisively state its specific role in isolation. Overall, our findings hint at a promising therapeutic potential for magnesium in managing menopausal symptoms, particularly when used alongside other beneficial nutrients.
I bought this for my mother during menopause. Good magnesium! It eliminates frequent hot flashes and normalises her mood, contributing to improved sleep and overall wellbeing.
Read More
9
Pain relief achieved
1 people found this helpful
It is essential right before my period. I take it when my uterus starts to contract, sometimes twice a day. I use it whenever I feel abdominal pain until bleeding occurs. Since entering menopause, I suffered from terrible menstrual pain and headaches, but this product has genuinely alleviated my suffering. I am incredibly grateful to live free from headache medication now.
Read More
9
Muscle tension relief
1 people found this helpful
The quality of this supplement surpassed my expectations. Its high-absorption magnesium ingredient effectively relieves muscle tension and significantly benefits sleep quality. It has also helped regulate hormones affected by menopause. It offers excellent value for money with a substantial number of capsules.
Read More
7.5
Menopause support confirmed
1 people found this helpful
I was taking affordable magnesium with good cost performance, and I've noticed a decrease in menopausal symptoms, leading to an overall better feeling. If it's in stock, I will purchase this again.
Read More
9
Central nervous system support
This works great! Magnesium is essential for the normal functioning of the central nervous system. My doctor prescribed this easily digestible form during menopause. The results include sound sleep and diminished anxiety, allowing me to feel calm and relaxed immediately. I highly recommend it!
Menopause is a natural biological process that marks the end of a woman's reproductive years, characterized by the cessation of menstruation and a decline in hormonal levels, particularly estrogen and progesterone. Typically occurring between the ages of 45 and 55, menopause can bring a variety of physical and emotional changes. Common symptoms may include hot flashes, night sweats, mood swings, and changes in sleep patterns. It is important to note that menopause is a gradual process and often begins with perimenopause, where women may experience irregular periods and increased symptoms for several years before periods stop completely.
While menopause is a natural phase of life, it can have significant impacts on a woman's health and well-being. This transition can increase the risk of certain health issues, such as osteoporosis and cardiovascular disease, due in part to lowered hormone levels. Therefore, it is advisable for women to consult with healthcare providers to discuss potential management strategies and lifestyle adjustments during this time. These may include hormone replacement therapy, dietary changes, regular physical activity, and alternative therapies, all aimed at alleviating symptoms and promoting overall health during and after menopause.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium is often highlighted for its potential benefits during menopause, although the evidence is not as comprehensive as one might hope. Some studies suggest that magnesium may help alleviate certain symptoms associated with menopause, such as mood swings, anxiety, and sleep disturbances. This mineral plays a crucial role in various bodily functions, including hormone regulation and stress response, which means that adequate magnesium levels might contribute to a smoother transition during this life stage.
In addition to its potential symptom-relieving properties, magnesium is also known for its overall health benefits, including supporting bone health, which is particularly important during menopause as women are at a higher risk for osteoporosis. It is generally advisable to maintain a balanced diet rich in magnesium through foods like leafy greens, nuts, seeds, and whole grains. However, it's always wise to consult with a healthcare provider before starting any supplementation, especially during menopause, to ensure it's safe and appropriate for your individual health needs.
Based on user reviews, the timeframe for seeing results from magnesium supplements during menopause can vary, but many users report experiencing benefits within a couple of weeks. For instance, one reviewer noted that their mother's struggle with severe insomnia improved significantly after just two weeks of taking the supplement (Read Review). Others highlighted improvements in sleep quality, decreased menopausal symptoms, and enhanced overall wellbeing also occurring within a similar timeframe, suggesting that some benefits may manifest relatively quickly.
However, it is essential to recognize that individual experiences can differ greatly. Some users signified longer-term benefits, appreciating improvements in sleeping patterns and alleviation of symptoms from ongoing use (Read Review; Read Review). Thus, while many may notice changes as soon as two weeks, full advantages might take longer, and consistent usage appears to yield the best results over time. As always, it's advisable to consult with a healthcare professional when considering supplement use during menopause.
Magnesium supplementation has shown promise in addressing some symptoms and health concerns associated with menopause, supported by various studies. For instance, research on ovariectomized female animals demonstrated that magnesium could positively influence metabolic health, inflammation, and oxidative stress, suggesting its potential as a therapeutic option during menopause [1]. Additionally, a different study indicated that magnesium could alleviate menopause-related disorders such as chronic pain and memory decline in animal models [2].
Furthermore, studies involving women have highlighted the importance of monitoring magnesium levels during menopause, as these levels tend to decrease during this transitional phase [4]. Notably, women with higher dietary magnesium intake exhibited better bone density outcomes [5]. While magnesium appears to have beneficial effects on menopausal symptoms and bone health, it is often most effective when combined with other nutrients [8]. In conclusion, scientific research suggests that magnesium could play a valuable role in menopause management, particularly when incorporated into a broader nutritional strategy.
Based on user reviews, many individuals have reported significant improvements in various menopausal symptoms after taking magnesium supplements. Numerous users highlighted the effectiveness of magnesium in regulating mood, reducing the intensity of hot flashes, and aiding in better sleep quality. For instance, one user mentioned that their mother experienced a considerable reduction in hot flashes and improved mood after starting magnesium, which contributed significantly to her overall wellbeing (Read Review). Another user found relief from menstrual pain and migraines, expressing gratitude for being able to live without headache medication (Read Review).
In addition to alleviating physical symptoms, many users reported enhanced mental clarity and reduced anxiety, which are critical during menopause. Users like one reviewer noted that taking magnesium led to a decrease in anxiety and improved tranquility, promoting better sleep and relaxation (Read Review). Several others mentioned improved sleep patterns as well, with some noting reduced insomnia after just a couple of weeks of supplementation (Read Review). Overall, while anecdotal evidence seems promising, it is essential to remember that individual results can vary, and users should consider consulting with a healthcare provider before starting any new supplement regimen.
Based on user reviews, many individuals report positive experiences when combining magnesium supplements with other supplements during menopause. One user noted that chelated magnesium taken alongside zinc provided enhanced benefits for sleep and joint support, particularly after menopause (Read Review). Another mentioned that magnesium complements their usage of magnesium oxide, illustrating its role in alleviating cramps and improving sleep quality during this transitional phase (Read Review).
Additionally, users described magnesium’s overall balance with other supplements as vital in managing the broader spectrum of menopausal symptoms. One reviewer emphasized magnesium's effectiveness in reducing pain from PMS and menstrual issues, highlighting its capability to stabilize hormonal fluctuations (Read Review). Overall, users seem to appreciate a comprehensive supplement strategy that integrates magnesium, indicating its synergistic effects when used alongside other key nutrients for menopausal relief.
Users report various experiences with magnesium supplementation for treating menopause, particularly highlighting its benefits for sleep quality, hormone regulation, and alleviating symptoms such as hot flashes and mood swings. Many users suggest a dosage of around 100-200 mg, noting that taking two pills before bed or adjusting based on individual need has proven effective. For instance, one user mentions, "I take two tablets twice a day to address sleep disorders related to menopause” Read Review, while another notes, “With menopause approaching, I take two pills before bed” Read Review.
Remarkably, the feedback also highlights that the form of magnesium, such as chelated or high-absorption types, contributes to its efficacy, optimizing the relief from symptoms. Users often report a significant improvement in sleep quality, mood stabilization, and a reduction in menstrual pain and headaches Read Review. Overall, magnesium appears to be a valuable addition for those navigating menopause, providing not just relief from discomfort but also enhancing overall wellbeing.
7.5
Insomnia relief achieved
It has been remarkably effective for insomnia. My mother struggled with severe insomnia during menopause, but after two weeks on this, the effects gradually appeared. Now, she can take it independently without my assistance. I’m thoroughly satisfied with the remarkable impact it has had on her sleep. The quality is also excellent, as it’s Dr. Best's product, so I trust and consume it myself.
7.5
Drowsiness alleviated
12 people found this helpful
For months, I've felt constantly sleepy, sick, and tired, attributing it to my age and menopause. However, magnesium has greatly improved my sleep quality. I was aware of its effectiveness, so I began taking it. The drowsiness and dullness I felt upon waking have significantly diminished, and I rarely experience brain fog while working from home. Magnesium is crucial and common deficiencies among Japanese people, thus I intend to keep taking it.
9
Hormonal balance
Under stress and with hormonal disorders like thyroid issues, hair loss, PMS, migraines, and menopause, I adore magnesium for its immediate benefits. It preserves hormones and effectively alleviates pain from menstruation, PMS, migraines, and menopause symptoms.
9
Mood stabilisation noted
2 people found this helpful
I bought this for my mother during menopause. Good magnesium! It eliminates frequent hot flashes and normalises her mood, contributing to improved sleep and overall wellbeing.
9
Pain relief achieved
1 people found this helpful
It is essential right before my period. I take it when my uterus starts to contract, sometimes twice a day. I use it whenever I feel abdominal pain until bleeding occurs. Since entering menopause, I suffered from terrible menstrual pain and headaches, but this product has genuinely alleviated my suffering. I am incredibly grateful to live free from headache medication now.
9
Central nervous system support
This works great! Magnesium is essential for the normal functioning of the central nervous system. My doctor prescribed this easily digestible form during menopause. The results include sound sleep and diminished anxiety, allowing me to feel calm and relaxed immediately. I highly recommend it!
9
Improved sleep quality
Chelated magnesium allows better absorption in the body. I take it regularly alongside zinc. It improves my sleep, benefits my joints, and is an excellent aid after menopause. I consume it consistently.
7.5
Cramps alleviated
Magnesium has eradicated my cramps since I started taking it, significantly aiding my constipation and improving my sleep. I initially took 2 tablets before bed, also using magnesium oxide for severe constipation. While my sleep quality is better, I noticed no change in headaches or depression. Given my menopause, I had hoped for more, but it was a relief to eliminate my cramps.
8
Sleep disorders
Magnesium aids muscle relaxation and enhances sleep quality. I take two tablets twice a day to address sleep disorders related to menopause.
7.5
Improved sleep quality
7 people found this helpful
Eat before going to bed, sleep well, and improve sleep quality. This 100 mg granule is much more cost-effective than capsules, although the volume is slightly larger, which takes a bit of getting used to. Previously, I'd bought 120 capsules, but this time I opted for 240 due to the good effects. With menopause approaching, I take two pills before bed and find one sufficient for my son. The benefits include falling asleep easily, waking up refreshed, and experiencing less discomfort. I hope my experience is helpful to you.
7
Magnesium aids menopausal metabolism
Utilizing a Combination of Supplements Comprising Boric Acid, Magnesium, Vitamin D3, and Extra Virgin Olive Oil to Improve Metabolism in Menopausal Ovariectomized Rats.
We conducted a study to understand how magnesium, along with other supplements, could influence metabolic health during menopause. Our research involved 42 adult female rats that were either ovariectomized or kept as controls. We divided them into seven groups to assess the effects of various treatments, including magnesium, boric acid, vitamin D3, extra virgin olive oil, and combinations of these supplements.
The results were promising. We observed significant improvements in markers related to inflammation, oxidative stress, and various metabolic parameters when magnesium was included in the treatment plans. Interestingly, the rats receiving magnesium, especially as part of a combined treatment, showed better results than those given individual supplements. This suggests that magnesium could play a valuable role in supporting metabolic health during menopause.
However, it’s worth noting that while magnesium demonstrated beneficial effects, the comprehensive impact of each supplement used individually wasn’t singled out for analysis. Thus, while magnesium appears to contribute positively, we cannot decisively state its specific role in isolation. Overall, our findings hint at a promising therapeutic potential for magnesium in managing menopausal symptoms, particularly when used alongside other beneficial nutrients.
9
Magnesium aids menopause-related issues
The Causal Role of Magnesium Deficiency in the Neuroinflammation, Pain Hypersensitivity and Memory/Emotional Deficits in Ovariectomized and Aged Female Mice.
We explored the connection between magnesium deficiency and various challenges commonly faced by postmenopausal women, such as chronic pain, memory decline, and mood disorders. Our research specifically focused on how magnesium supplementation can help in alleviating these issues in ovariectomized and aged female mice—modeling the postmenopausal state.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
4
Magnesium impact on menopause assessed
Activities of Serum Magnesium and Thyroid Hormones in Pre-, Peri-, and Post-menopausal Women.
We conducted a study to understand how magnesium levels and thyroid hormone activities relate to the experiences of women who are pre-, peri-, and post-menopausal. Our group comprised 165 women who were carefully selected based on specific criteria, alongside an equal number of age-matched control participants. These subjects were all patients at Prathima Institute of Medical Sciences in Karimnagar, India.
We collected blood samples to measure magnesium and thyroid hormones levels, specifically tetra-iodothyronine (T4), tri-iodothyronine (T3), and thyroid-stimulating hormone (TSH). What we found was quite revealing: there was a notable difference in magnesium levels and thyroid hormones between our study participants and the control group.
Notably, magnesium levels tended to decrease as women transitioned through peri- and post-menopausal stages. For instance, our findings showed a drop in magnesium levels from an average of 1.72 in pre-menopausal women to just 1.60 in postmenopausal women. Conversely, TSH levels were on the rise, indicating hormonal changes, with postmenopausal women showing the highest TSH levels at 7.19.
Therefore, we concluded that women approaching menopause might experience low magnesium levels, potentially leading to thyroid and other hormonal disorders. This highlights the importance of monitoring and managing magnesium levels during this transitional phase in a woman's life.
7
Magnesium impacts menopause bone health
Magnesium Intake Predicts Bone Turnover in Postmenopausal Black South African Women.
We explored the relationship between magnesium intake and bone health in postmenopausal black South African women over a two-year period. In this study, which included 144 participants, researchers measured bone mineral density (BMD) at several key sites, alongside various biochemical analyses, including bone turnover markers.
The findings highlighted that higher dietary magnesium intake was linked to lower levels of C-Telopeptide of type I collagen (CTX-1), indicating reduced bone resorption. Moreover, calcium intake showed a positive correlation with BMD at the distal radius both at the start and end of the study.
Interestingly, one dietary pattern—snacking—also related to BMD scores over time, suggesting that what we eat can influence our bone health as we age. The results revealed that magnesium intake alone predicted a notable portion of the changes in bone turnover, emphasizing its potential role in supporting bone health during menopause.
Overall, this study suggests that paying attention to magnesium in our diets could be beneficial for women navigating menopause, especially regarding bone health.
9
Magnesium reduces menopause symptoms
Effects of a new combination of nutraceuticals on postmenopausal symptoms and metabolic profile: a crossover, randomized, double-blind trial.
We explored the effects of a nutraceutical blend, including magnesium, on menopause symptoms through a crossover trial involving 43 postmenopausal women.
Participants experienced significant reductions in menopause symptoms, as measured by the Menopause Rating Scale, after using the nutraceuticals.
Additionally, improvements were noted in cardiovascular risk factors, such as lower cholesterol levels and blood pressure.
Overall, this study suggests that magnesium, combined with other nutrients, may provide meaningful relief for postmenopausal symptoms.
References
Atteia HH, Ahmed SF, Askar ME, Sakr AT. Utilizing a Combination of Supplements Comprising Boric Acid, Magnesium, Vitamin D3, and Extra Virgin Olive Oil to Improve Metabolism in Menopausal Ovariectomized Rats. Biol Trace Elem Res. 2024. doi:10.1007/s12011-024-04476-y
Zhang J, Mai CL, Xiong Y, Lin ZJ, Jie YT, et al. The Causal Role of Magnesium Deficiency in the Neuroinflammation, Pain Hypersensitivity and Memory/Emotional Deficits in Ovariectomized and Aged Female Mice. J Inflamm Res. 2021;14:6633. doi:10.2147/JIR.S330894
Chen PC, Lee YC, Jao HY, Wang CP, Jacobs A, et al. Supplementation of nanofiltrated deep ocean water ameliorate the progression of osteoporosis in ovariectomized rat via regulating osteoblast differentiation. J Food Biochem. 2020;44:e13236. doi:10.1111/jfbc.13236
Kolanu BR, Vadakedath S, Boddula V, Kandi V. Activities of Serum Magnesium and Thyroid Hormones in Pre-, Peri-, and Post-menopausal Women. Cureus. 2020;12:e6554. doi:10.7759/cureus.6554
Wright HH, Kruger MC, Schutte WD, Wentzel-Viljoen E, Kruger IM, et al. Magnesium Intake Predicts Bone Turnover in Postmenopausal Black South African Women. Nutrients. 2019;11. doi:10.3390/nu11102519
Lambert MNT, Thybo CB, Lykkeboe S, Rasmussen LM, Frette X, et al. Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial. Am J Clin Nutr. 2017;106:909. doi:10.3945/ajcn.117.153353
McCabe D, Lisy K, Lockwood C, Colbeck M. The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a systematic review. JBI Database System Rev Implement Rep. 2017;15:402. doi:10.11124/JBISRIR-2016-002965
Trimarco V, Rozza F, Izzo R, De Leo V, Cappelli V, et al. Effects of a new combination of nutraceuticals on postmenopausal symptoms and metabolic profile: a crossover, randomized, double-blind trial. Int J Womens Health. 2016;8:581.