Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.4
USERS' SCORE
Good
Based on 132 Reviews
8.1
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Magnesium (from 2,000 mg magnesium lysinate glycinate chelate) (Albion®)
200 mg
48%

Top Medical Research Studies

We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.

Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.

We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Read More
8
Magnesium aids migraine prevention
We observed that magnesium plays a notable role in migraine prevention and treatment. Specifically, magnesium is recommended for both chronic migraine management and immediate intravenous relief during acute migraine episodes. The use of magnesium appears to be linked with mild gastrointestinal side effects, indicating that it is generally well-tolerated by those who use it.

Although individual responses may vary, magnesium has shown promising results for many people managing migraines. It's essential to consider this approach alongside other treatments, as magnesium supplementation might enhance overall migraine management. For those looking for alternative or complementary options, magnesium could be a viable choice worth exploring further.
Read More
9
Magnesium significantly alleviates migraines
We explored how magnesium supplementation affects the frequency and intensity of migraine attacks. The study relied on evidence gathered from twenty-two randomized controlled trials, providing a solid foundation for our findings.

Through a detailed analysis, we found that magnesium supplementation significantly reduced migraine attacks, with a marked decrease in severity and the number of days afflicted each month. Specifically, magnesium showed a mean difference of -2.51 in attack frequency and -0.88 in severity compared to those who did not receive the supplement.

This promising outcome suggests that magnesium could be an effective option for individuals seeking migraine relief. As we delved deeper into the study, it became clear that while additional research is needed to establish long-term effects, magnesium’s immediate benefits in reducing migraines are noteworthy.
Read More

Most Useful Reviews

10
Migraine relief
242 people found this helpful
I have been taking this wonderful medication for a year and a half, and during this time, I have eliminated my main issue - migraines.
Read More
8
Eased migraine symptoms
104 people found this helpful
Doctor's Best magnesium normalises sleep and has significantly improved my migraines. I take it regularly, and when I do, both migraines and PMS become much easier to manage. I also take omega-3s, which may contribute to my overall improvement.
Read More
10
Migraine prevention
56 people found this helpful
After years of crippling migraines, I discovered magnesium deficiency was a trigger. Taking 400-800 mg daily has drastically reduced my headaches to just two in the past ten months.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.4
  • All Researches
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.

Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.

We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Read More
9
Magnesium significantly alleviates migraines
We explored how magnesium supplementation affects the frequency and intensity of migraine attacks. The study relied on evidence gathered from twenty-two randomized controlled trials, providing a solid foundation for our findings.

Through a detailed analysis, we found that magnesium supplementation significantly reduced migraine attacks, with a marked decrease in severity and the number of days afflicted each month. Specifically, magnesium showed a mean difference of -2.51 in attack frequency and -0.88 in severity compared to those who did not receive the supplement.

This promising outcome suggests that magnesium could be an effective option for individuals seeking migraine relief. As we delved deeper into the study, it became clear that while additional research is needed to establish long-term effects, magnesium’s immediate benefits in reducing migraines are noteworthy.
Read More
We examined how magnesium oxide (MgO), both alone and with riboflavin, helps prevent migraines in pregnant individuals. This retrospective study included 203 patients treated between 2015 and 2020, analyzing outcomes such as migraine frequency, severity, and duration.

We found that both treatment options reduced migraines significantly, with 77% of participants experiencing improvement in associated symptoms. The results indicate that magnesium oxide can be an effective option for managing migraines during pregnancy, making it a potential consideration for expectant mothers suffering from this condition.
Read More
8
Magnesium aids migraine prevention
We observed that magnesium plays a notable role in migraine prevention and treatment. Specifically, magnesium is recommended for both chronic migraine management and immediate intravenous relief during acute migraine episodes. The use of magnesium appears to be linked with mild gastrointestinal side effects, indicating that it is generally well-tolerated by those who use it.

Although individual responses may vary, magnesium has shown promising results for many people managing migraines. It's essential to consider this approach alongside other treatments, as magnesium supplementation might enhance overall migraine management. For those looking for alternative or complementary options, magnesium could be a viable choice worth exploring further.
Read More
We examined the potential role of magnesium, along with other natural ingredients, in reducing the severity and frequency of symptoms associated with vestibular migraine (VM). This observational study involved a questionnaire-based approach where we encouraged patients to consider lifestyle changes alongside an over-the-counter supplement containing magnesium and other components.

Over a three-month period, we collected data from 82 participants, focusing on symptom severity using various assessment tools. We found that there was a notable decrease in the reported severity and frequency of VM symptoms. Patients indicated improvements in their discomfort levels, with around 50% reporting better outcomes.

While magnesium was part of a combination therapy, our findings suggest that nonprescription treatments can significantly impact VM symptoms. This offers a positive outlook for individuals seeking alternative management strategies for their migraines without relying solely on prescription medications.
Read More

User Reviews

USERS' SCORE
Good
Based on 132 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Migraine relief
242 people found this helpful
I have been taking this wonderful medication for a year and a half, and during this time, I have eliminated my main issue - migraines.
Read More
8
Eased migraine symptoms
104 people found this helpful
Doctor's Best magnesium normalises sleep and has significantly improved my migraines. I take it regularly, and when I do, both migraines and PMS become much easier to manage. I also take omega-3s, which may contribute to my overall improvement.
Read More
10
Migraine prevention
56 people found this helpful
After years of crippling migraines, I discovered magnesium deficiency was a trigger. Taking 400-800 mg daily has drastically reduced my headaches to just two in the past ten months.
Read More
9
Muscle pain relief
50 people found this helpful
This magnesium is excellent, with a great price-quality ratio. It supports the nervous system and relieves muscle pain during migraines effectively. I take it daily and feel its benefits.
Read More
10
Sleep improvement
23 people found this helpful
I previously suffered migraines, but since using this supplement, I sleep soundly and have not experienced migraines on bad weather days.
Read More

Frequently Asked Questions

9
Migraine reduction
4 people found this helpful
I started taking it for migraines and felt results after about two weeks. My morning headaches are now gone, and I rarely need medication.
9
Fatigue elimination
8 people found this helpful
As a busy working mum, I faced fatigue, headaches, and migraines. After a blood test revealed deficiencies, I tried magnesium based on positive reviews. After just one night, my migraines and headaches disappeared, and I finally felt energised and alive again.
10
Migraine relief
242 people found this helpful
I have been taking this wonderful medication for a year and a half, and during this time, I have eliminated my main issue - migraines.
10
Migraine prevention
56 people found this helpful
After years of crippling migraines, I discovered magnesium deficiency was a trigger. Taking 400-800 mg daily has drastically reduced my headaches to just two in the past ten months.
8
Eased migraine symptoms
104 people found this helpful
Doctor's Best magnesium normalises sleep and has significantly improved my migraines. I take it regularly, and when I do, both migraines and PMS become much easier to manage. I also take omega-3s, which may contribute to my overall improvement.
9
Migraine relief
10 people found this helpful
I experienced migraine headaches and facial cramps, but taking two tablets before bed has been a game changer. If I forget to take them and start to get a migraine, I take them immediately and it helps prevent the headache. I highly recommend magnesium for anyone with similar issues.
9
No migraines observed
10 people found this helpful
It's been a month since I started taking one tablet of this magnesium with riboflavin each morning, and I haven't had a single migraine. Before this, I experienced headaches almost twice a week. I am thrilled as migraines used to leave me incapacitated.
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.

Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.

We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
We explored the role of magnesium as a potential treatment for migraines through a review of existing literature. Migraines can be intense and debilitating, impacting many individuals' day-to-day lives. Our focus was on understanding whether supplementing magnesium could help in preventing or managing these attacks.

Some studies suggest that low levels of magnesium may be linked to more frequent or severe migraine episodes. When people suffer from migraines, inflammation and oxidative stress might contribute to their pain, and magnesium appears to play a role in helping regulate these processes. By supporting brain health and energy metabolism, magnesium could potentially mitigate some of the triggers associated with migraines.

Although the evidence does point to benefits from magnesium supplementation, we noted that more extensive, well-controlled studies are necessary to draw firm conclusions. Overall, while magnesium shows promise, it may not be a standalone solution and could work best in combination with other treatments.
We aimed to explore the connection between magnesium levels in the body and migraine occurrences. In our research, we compared the magnesium levels of 25 patients diagnosed with migraine to 25 healthy control individuals. Both groups were selected from health facilities in Sinop, Brazil.

The analysis revealed that both plasma and erythrocyte magnesium levels were significantly lower in the migraine group. Specifically, plasma magnesium was measured at 0.172 mg/L for migraine sufferers versus 0.197 mg/L in the control group. Similarly, erythrocyte magnesium levels were 0.393 mg/L for those with migraines, compared to 0.432 mg/L for healthy participants.

Importantly, we determined that measuring magnesium in erythrocytes is a more reliable indicator of magnesium status in migraine patients than plasma measurements. Overall, our findings suggest a notable association between low magnesium levels and migraine, revealing potential avenues for dietary or supplemental magnesium as a management strategy for individuals suffering from migraines.
8
Magnesium aids migraine prevention
We observed that magnesium plays a notable role in migraine prevention and treatment. Specifically, magnesium is recommended for both chronic migraine management and immediate intravenous relief during acute migraine episodes. The use of magnesium appears to be linked with mild gastrointestinal side effects, indicating that it is generally well-tolerated by those who use it.

Although individual responses may vary, magnesium has shown promising results for many people managing migraines. It's essential to consider this approach alongside other treatments, as magnesium supplementation might enhance overall migraine management. For those looking for alternative or complementary options, magnesium could be a viable choice worth exploring further.
We observed that magnesium is often mentioned in discussions about effective treatments for migraines. This mineral plays a vital role in many bodily functions, and its potential to alleviate migraine symptoms is supported by anecdotal evidence.

Our analysis points out that while magnesium is particularly noted for its benefits, the details surrounding its standalone effectiveness in managing migraines remain unclear. It seems to work best when combined with lifestyle changes such as stress management and sleep hygiene, as well as with dietary adjustments that avoid common migraine triggers.

We understand that people looking for relief from migraines may find hope in using magnesium supplements. However, it's essential to highlight that in the broader context of migraine treatments, magnesium alone may not completely resolve the issue for everyone. So, while some individuals report improvements, it's not a one-size-fits-all solution.

References

  1. Dominguez LJ, Veronese N, Sabico S, Al-Daghri NM, Barbagallo M. Magnesium and Migraine. Nutrients. 2025;17. doi:10.3390/nu17040725
  2. Tepper SJ, Tepper K. Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur. Curr Pain Headache Rep. 2025;29:33. doi:10.1007/s11916-025-01358-3
  3. Hajhashemy Z, Golpour-Hamedani S, Eshaghian N, Sadeghi O, Khorvash F, et al. Practical supplements for prevention and management of migraine attacks: a narrative review. Front Nutr. 2024;11:1433390. doi:10.3389/fnut.2024.1433390
  4. Talandashti MK, Shahinfar H, Delgarm P, Jazayeri S. Effects of selected dietary supplements on migraine prophylaxis: A systematic review and dose-response meta-analysis of randomized controlled trials. Neurol Sci. 2025;46:651. doi:10.1007/s10072-024-07794-0
  5. Gazerani P, Papetti L, Dalkara T, Cook CL, Webster C, et al. The Brain, the Eating Plate, and the Gut Microbiome: Partners in Migraine Pathogenesis. Nutrients. 2024;16. doi:10.3390/nu16142222
  6. Hannigan IP, Rosengren SM, Di Tanna GL, Watson SRD, Welgampola MS. Effects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study. Intern Med J. 2024;54:916. doi:10.1111/imj.16314
  7. Kurhade PI, Kodape SM, Das A, Bansod PG. Synergistic action of sumatriptan delivery and targeting magnesium deficiency using green, pH-responsive MgO nanoparticles synthesized from mahua flower extracts. Environ Sci Pollut Res Int. 2023. doi:10.1007/s11356-023-30648-9
  8. Umemoto KK, Tawk K, Mazhari N, Abouzari M, Djalilian HR. Management of Migraine-Associated Vestibulocochlear Disorders. Audiol Res. 2023;13:528. doi:10.3390/audiolres13040047
  9. Gaul C, Zaranek L, Goßrau G. [Complementary and supplementary procedures in the treatment of headache]. Schmerz. 2023;37:448. doi:10.1007/s00482-023-00738-1
  10. Shenoy NN, Gheewala GK, Kedambadi R, Pai S, Zulfikli KM, et al. Can Serum Magnesium Level and Visual Evoked Potentials (P100) be a Predictive in Migraineurs?: Evidence Based Study. Neurol India. 2023;71:463. doi:10.4103/0028-3886.378668
  11. Frank M, Abouzari M, Djalilian HR. Meniere's disease is a manifestation of migraine. Curr Opin Otolaryngol Head Neck Surg. 2023;31:313. doi:10.1097/MOO.0000000000000908
  12. Pawar V, Ashraf H, Dorsala S, Mary P, Hameed N, et al. Motorist's Vestibular Disorientation Syndrome (MVDS)-Proposed Diagnostic Criteria. J Pers Med. 2023;13. doi:10.3390/jpm13050732
  13. Hoshino MT, Bochio MG, Spagnol Bonache J, Ludwig L, Leandro de Campos M, et al. Plasma and erythrocyte magnesium levels: from validation of the method to analysis in volunteers diagnosed to migraine. Magnes Res. 2022;35:51. doi:10.1684/mrh.2022.0502
  14. Mahajan R, Anand KS, Mahajan RK, Garg J, Juneja A. Serum Magnesium Levels During the Ictal and Interictal Phase in Patients of Migraine: A Prospective Observational Study. Neurol India. 2022;70:1852. doi:10.4103/0028-3886.359247
  15. Bhurat R, Premkumar S, Manokaran RK. Serum Magnesium Levels in Children With and Without Migraine: A Cross-Sectional Study. Indian Pediatr. 2022;59:623.
  16. Mazza GR, Solorio C, Stek AM, Kalayjian LA, Wilson ML, et al. Assessing the efficacy of magnesium oxide and riboflavin as preventative treatment of migraines in pregnancy. Arch Gynecol Obstet. 2023;308:1749. doi:10.1007/s00404-022-06872-y
  17. Ariyanfar S, Razeghi Jahromi S, Togha M, Ghorbani Z. Review on Headache Related to Dietary Supplements. Curr Pain Headache Rep. 2022;26:193. doi:10.1007/s11916-022-01019-9
  18. Guerrero-Toro C, Koroleva K, Ermakova E, Gafurov O, Abushik P, et al. Testing the Role of Glutamate NMDA Receptors in Peripheral Trigeminal Nociception Implicated in Migraine Pain. Int J Mol Sci. 2022;23. doi:10.3390/ijms23031529
  19. Matin H, Taghian F, Chitsaz A. Artificial intelligence analysis to explore synchronize exercise, cobalamin, and magnesium as new actors to therapeutic of migraine symptoms: a randomized, placebo-controlled trial. Neurol Sci. 2022;43:4413. doi:10.1007/s10072-021-05843-6
  20. Karim MR, Bhattacharjee M, Islam MS, Banerjee S, Hossain S, et al. Relation between Serum Magnesium Level and Migraine. Mymensingh Med J. 2021;30:301.
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