Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.1
USERS' SCORE
Moderately Good
Based on 10 Reviews
7.5
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Magnesium (from 2,000 mg magnesium lysinate glycinate chelate) (Albion®)
200 mg
48%
Top Medical Research Studies
9
We examined the role of magnesium alginate in treating laryngopharyngeal reflux (LPR), which causes symptoms like voice issues, swallowing difficulties, and coughing. In a study involving 100 outpatients, patients were treated with alginate for two months, visiting at the start and then at 15, 30, and 60 days.
The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
Read More
8
We conducted a multicenter crossover study to see if magnesium alginate could alleviate reflux symptoms in infants. A total of 72 infants participated, receiving either magnesium alginate or a thickened formula in alternating phases.
Our findings showed a significant reduction in reflux symptoms across all infant groups. However, there was no significant difference in effectiveness between the two treatments. Importantly, using magnesium alginate also yielded cost savings of about €4.60 per infant compared to the thickened formula.
Thus, magnesium alginate appears to be a cost-effective option without sacrificing symptom relief.
Our findings showed a significant reduction in reflux symptoms across all infant groups. However, there was no significant difference in effectiveness between the two treatments. Importantly, using magnesium alginate also yielded cost savings of about €4.60 per infant compared to the thickened formula.
Thus, magnesium alginate appears to be a cost-effective option without sacrificing symptom relief.
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7
We explored the effectiveness of Gaviscon® Advance, both alone and alongside proton pump inhibitors (PPIs), in treating laryngopharyngeal reflux (LPR).
One hundred patients participated in this study, all treated with Gaviscon® Advance and monitored over three months.
The findings indicated that while Gaviscon® Advance is effective on its own, combining it with a high-dose PPI did not enhance symptom relief.
This suggests that Gaviscon® Advance can be a sufficient treatment for LPR without needing the added PPI.
One hundred patients participated in this study, all treated with Gaviscon® Advance and monitored over three months.
The findings indicated that while Gaviscon® Advance is effective on its own, combining it with a high-dose PPI did not enhance symptom relief.
This suggests that Gaviscon® Advance can be a sufficient treatment for LPR without needing the added PPI.
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Most Useful Reviews
9
Reduces burning sensation
2 people found this helpful
Doctor prescribed antacids for acid reflux, but I opted for a natural remedy. Whenever I feel a burn in my stomach, I take a few of these tablets and find I no longer need antacids. It also aids digestion.
Read More
10
Good digestion
A high-quality product that my body digests easily. I have not experienced acid reflux with this product.
Read More
9
Effective for reflux
I researched acid reflux and learned this magnesium type helps. I bought it for a relative, and they swear it alleviates their acid reflux.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.1
- All Researches
9.5
Gaviscon DA effectively neutralizes acid
We explored how Gaviscon Double Action, a combination of alginate and antacid, affects gastric acid levels. In a carefully designed crossover study, we monitored intragastric pH in healthy volunteers after administering Gaviscon DA versus a placebo.
The results showed a clear advantage for Gaviscon DA, with pH levels reaching 4 or higher nearly 47% of the time, compared to just 5% for the placebo. This confirms that Gaviscon DA effectively neutralizes gastric acid, enhancing the understanding of how its components work together for reflux relief.
The results showed a clear advantage for Gaviscon DA, with pH levels reaching 4 or higher nearly 47% of the time, compared to just 5% for the placebo. This confirms that Gaviscon DA effectively neutralizes gastric acid, enhancing the understanding of how its components work together for reflux relief.
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9
Banxia Houpu Decoction shows promise
We evaluated how Banxia Houpu Decoction, a traditional Chinese remedy, can help patients with refractory gastroesophageal reflux disease (RGERD). In our study involving 89 patients, we compared this decoction to standard Western treatments, including proton pump inhibitors with added magnesium aluminum carbonate.
Results showed that the decoction significantly improved throat burning, swallowing difficulties, and hiccups more effectively than Western treatments. However, the Western medicine group had better relief for heartburn and gastric burning sensations.
Factors like age and gastroesophageal flap valve grade also impacted treatment effectiveness.
Results showed that the decoction significantly improved throat burning, swallowing difficulties, and hiccups more effectively than Western treatments. However, the Western medicine group had better relief for heartburn and gastric burning sensations.
Factors like age and gastroesophageal flap valve grade also impacted treatment effectiveness.
Read More
9
We examined the role of magnesium alginate in treating laryngopharyngeal reflux (LPR), which causes symptoms like voice issues, swallowing difficulties, and coughing. In a study involving 100 outpatients, patients were treated with alginate for two months, visiting at the start and then at 15, 30, and 60 days.
The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
Read More
9
We aimed to observe how effective Weisu granules are on laryngopharyngeal reflux by randomly assigning 180 patients into three groups.
The experimental group received a combination of Lanqin oral solution and Weisu granules, while the control groups used either Lanqin alone or Esomeprazole with Lanqin.
After four weeks, the experimental group showed a remarkable 91.7% improvement, much higher than the 73.3% in control group A. Although the experimental group differed significantly from control group A, results were similar to control group B, indicating no major advantage over Esomeprazole.
The experimental group received a combination of Lanqin oral solution and Weisu granules, while the control groups used either Lanqin alone or Esomeprazole with Lanqin.
After four weeks, the experimental group showed a remarkable 91.7% improvement, much higher than the 73.3% in control group A. Although the experimental group differed significantly from control group A, results were similar to control group B, indicating no major advantage over Esomeprazole.
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8
GutGard® shows promise for GER
We evaluated how GutGard®, a specific liquorice extract, impacts symptoms of gastroesophageal reflux (GER) compared to a placebo. In a well-structured study, participants were randomly assigned to either a GutGard® group or a placebo group for 28 days.
Our findings suggest that those taking GutGard® experienced quicker relief from symptoms like heartburn and regurgitation, showing improvements within just two weeks. This indicates that GutGard® could be an effective option for managing GER symptoms.
Our findings suggest that those taking GutGard® experienced quicker relief from symptoms like heartburn and regurgitation, showing improvements within just two weeks. This indicates that GutGard® could be an effective option for managing GER symptoms.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 10 Reviews
7.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reduces burning sensation
2 people found this helpful
Doctor prescribed antacids for acid reflux, but I opted for a natural remedy. Whenever I feel a burn in my stomach, I take a few of these tablets and find I no longer need antacids. It also aids digestion.
Read More
10
Good digestion
A high-quality product that my body digests easily. I have not experienced acid reflux with this product.
Read More
9
Effective for reflux
I researched acid reflux and learned this magnesium type helps. I bought it for a relative, and they swear it alleviates their acid reflux.
Read More
9
Improves LPR symptoms
I read that magnesium can assist with LPR, a type of acid reflux. I experience this issue after antibiotics. This product has significantly improved my condition; I'm approximately 90% better.
Read More
7.5
Prevents reflux
Magnesium glycinate is the most bioavailable form. Glycine aids sleep and calmness, and it helps prevent reflux without causing loose stools.
Read More
Frequently Asked Questions
9
Improves LPR symptoms
I read that magnesium can assist with LPR, a type of acid reflux. I experience this issue after antibiotics. This product has significantly improved my condition; I'm approximately 90% better.
7.5
Quality ingredient
The quality of the ingredients is excellent. It's very helpful for acid reflux and GERD. I've been using it for 20 days, and I can now sleep well. My anxiety has greatly decreased.
2
Increased stomach acid
These are nice small tablets, but I've noticed an increase in stomach acid reflux after taking them, and my dog seems to experience it too! It's curious; perhaps they relax the stomach valve too much? I will continue with them and hope for improvement.
9
Reduces burning sensation
2 people found this helpful
Doctor prescribed antacids for acid reflux, but I opted for a natural remedy. Whenever I feel a burn in my stomach, I take a few of these tablets and find I no longer need antacids. It also aids digestion.
0
Caused reflux issue
Not a fan. It gave me acid reflux for some reason, so I had to switch to a different brand.
7.5
Neutralises stomach acid
This product effectively neutralises stomach acid and is beneficial to take along with digestive enzymes to help control acid reflux.
7.5
Prevents reflux
Magnesium glycinate is the most bioavailable form. Glycine aids sleep and calmness, and it helps prevent reflux without causing loose stools.
8
GutGard® shows promise for GER
We evaluated how GutGard®, a specific liquorice extract, impacts symptoms of gastroesophageal reflux (GER) compared to a placebo. In a well-structured study, participants were randomly assigned to either a GutGard® group or a placebo group for 28 days.
Our findings suggest that those taking GutGard® experienced quicker relief from symptoms like heartburn and regurgitation, showing improvements within just two weeks. This indicates that GutGard® could be an effective option for managing GER symptoms.
Our findings suggest that those taking GutGard® experienced quicker relief from symptoms like heartburn and regurgitation, showing improvements within just two weeks. This indicates that GutGard® could be an effective option for managing GER symptoms.
7
Magnesium alginate non-inferior to PPIs
We examined how magnesium alginate, specifically Gastrotuss, compares to the commonly used proton pump inhibitor, Omeprazole, for treating laryngopharyngeal reflux (LPR). In a non-inferiority randomized controlled trial involving 50 patients, both treatments showed a significant reduction in LPR symptoms after two months.
While both options were effective, alginate was found to be non-inferior to PPIs, suggesting it could be a viable alternative for individuals looking for treatments with fewer side effects.
While both options were effective, alginate was found to be non-inferior to PPIs, suggesting it could be a viable alternative for individuals looking for treatments with fewer side effects.
8
Gaviscon Advance outperforms antacid treatment
We investigated whether Gaviscon Advance or a non-alginate antacid was more effective at reducing acid reflux risk in obese individuals after late-night meals. In a clinical trial, participants were randomly assigned to receive one of the two medications after dinner.
Findings showed that Gaviscon Advance significantly suppressed the acid pocket and reduced symptoms like regurgitation better than the non-alginate antacid. This suggests that Gaviscon Advance may be a better treatment option for obesity-related reflux following late-night eating.
Findings showed that Gaviscon Advance significantly suppressed the acid pocket and reduced symptoms like regurgitation better than the non-alginate antacid. This suggests that Gaviscon Advance may be a better treatment option for obesity-related reflux following late-night eating.
References
- Raj JP, Saxena U, Belhekar MN, Mamde A, Darak H, et al. Efficacy and Safety of GutGard® in Managing Gastroesophageal Reflux-Related Symptoms: A Phase III, Single-Centre, Double-Blind, Randomized Placebo-Controlled Trial. Complement Med Res. 2025;32:26. doi:10.1159/000543367
- Song S, Zhang Y, Zhang J, Jiang Y, Gong A. Efficacy evaluation and exploratory analysis of influencing factors of Banxia Houpu Decoction in the treatment of refractory gastroesophageal reflux disease. Medicine (Baltimore). 2024;103:e38045. doi:10.1097/MD.0000000000038045
- Pizzorni N, Ambrogi F, Eplite A, Rama S, Robotti C, et al. Magnesium alginate versus proton pump inhibitors for the treatment of laryngopharyngeal reflux: a non-inferiority randomized controlled trial. Eur Arch Otorhinolaryngol. 2022;279:2533. doi:10.1007/s00405-021-07219-0
- Ciprandi G, Damiani V, Passali FM, Crisanti A, Motta G, et al. Magnesium alginate in patients with laryngopharyngeal reflux. J Biol Regul Homeost Agents. 2021;35:61. doi:10.23812/21-1supp2-12
- Deraman MA, Abdul Hafidz MI, Lawenko RM, Ma ZF, Wong MS, et al. Randomised clinical trial: the effectiveness of Gaviscon Advance vs non-alginate antacid in suppression of acid pocket and post-prandial reflux in obese individuals after late-night supper. Aliment Pharmacol Ther. 2020;51:1014. doi:10.1111/apt.15746
- Dragomiretska NV, Babov KD, Gushcha SG, Zabolotna IB, Plakida AL, et al. Application of mineral waters in the complex treatment of patients with gastroesophageal reflux disease. Minerva Gastroenterol Dietol. 2020;66:225. doi:10.23736/S1121-421X.20.02601-X
- Baldassarre ME, Di Mauro A, Pignatelli MC, Fanelli M, Salvatore S, et al. Magnesium Alginate in Gastro-Esophageal Reflux: A Randomized Multicenter Cross-Over Study in Infants. Int J Environ Res Public Health. 2019;17. doi:10.3390/ijerph17010083
- Wilkinson J, Abd-Elaziz K, den Daas I, Wemer J, van Haastert M, et al. Two placebo-controlled crossover studies in healthy subjects to evaluate gastric acid neutralization by an alginate-antacid formulation (Gaviscon Double Action). Drug Dev Ind Pharm. 2019;45:430. doi:10.1080/03639045.2018.1546314
- Wilkie MD, Fraser HM, Raja H. Gaviscon® Advance alone versus co-prescription of Gaviscon® Advance and proton pump inhibitors in the treatment of laryngopharyngeal reflux. Eur Arch Otorhinolaryngol. 2018;275:2515. doi:10.1007/s00405-018-5079-0
- Zhuang XY, Yang HZ, Wang HG, Li CW. [Clinical observation of Weisu granules in treating laryngopharyngeal reflux]. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018;32:369. doi:10.13201/j.issn.1001-1781.2018.05.012
- Bianchetti M, Peralta S, Nicita R, Aragona SE, Ciprandi G. Emerging from gastroesophageal reflux (EMERGE): An Italian survey - II the viewpoint of the patient. J Biol Regul Homeost Agents. 2018;32:983.
