Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
USERS' SCORE
Good
Based on 7 Reviews
8.4
Supplement Facts
Serving Size:  1 Veggie Capsule
Amount Per Serving
%DV
Vitamin C (as ascorbic acid)
40 mg
44%
Thiamin (as thiamin HCl)
60 mg
5000%
Riboflavin (as riboflavin and riboflavin-5-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
50 mg
313%
Vitamin B6 (from pyridoxine HCl and pyridoxal-5-phosphate)
50 mg
2941%
Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt) (Quatrefolic®)
400 mcg DFE
100%
Vitamin B12 (as methylcobalamin)
1000 mcg
41677%
Biotin
600 mcg
2000%
Pantothenic Acid (as d-calcium pantothenate)
100 mg
2000%

Top Medical Research Studies

9
Thiamine enhances memory in hypothyroidism
We explored the impact of thiamine (Vitamin B1) on memory and learning in rats with hypothyroidism. In a study involving 50 young rats, we treated them with a hypothyroid-inducing agent and varying doses of thiamine over seven weeks.

The results were promising—thiamine improved memory in rats as evidenced by better performance in timed tests. Specifically, higher doses of thiamine led to increased memory retention and reduced oxidative stress. This suggests that thiamine could be a beneficial supplement for addressing memory issues related to hypothyroidism.
Read More
8
Vitamin B benefits hypothyroidism treatment
We aimed to explore how B vitamins, including pyridoxine, betaine, folic acid, and cyanocobalamin, can correct homocysteine metabolism disrupted by hypothyroidism. By studying experimental rats treated for prolonged periods, we found that hypothyroidism severely reduced the activity of key enzymes involved in methylation, which in turn raised homocysteine levels—linked to heart disease risk.

Our findings indicate that B vitamins have a promising potential to lower these harmful homocysteine levels and could help prevent complications like endothelial dysfunction in hypothyroid patients.
Read More
7
Vitamin B12 deficiency linked to hypothyroidism
We explored the connection between vitamin B12 levels and hypothyroidism in a study involving 100 patients. A significant 68% of these patients were found to be vitamin B12 deficient, with a notable correlation to the presence of anti TPO and anti Thyroglobulin antibodies.

This suggests that vitamin B12 may play a role in the symptoms experienced by hypothyroid individuals, especially since thyroid hormones influence the production of red blood cells. While supplementation could potentially help alleviate these symptoms, further research is essential to confirm its effectiveness in routine treatment.
Read More

Most Useful Reviews

9
Metabolism improvement
11 people found this helpful
I take this B vitamin supplement daily after breakfast as I have hypothyroidism and experience a low metabolism. It's a safe product due to its modest dosage. I've noticed that my metabolism improves, making my body feel more active, enhancing brain circulation, and alleviating my depression. I highly recommend it.
Read More
9
Repeat purchase
I continually repurchase this excellent B complex and folate supplement for my thyroid issues, including hypothyroidism and Hashimoto's.
Read More
8
Iron assimilation support
This vitamin B supplement is beneficial for iron assimilation, nerve endings, and more, especially with my hypothyroidism. Its effectiveness gives me confidence to recommend it.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
  • All Researches
9
Thiamine enhances memory in hypothyroidism
We explored the impact of thiamine (Vitamin B1) on memory and learning in rats with hypothyroidism. In a study involving 50 young rats, we treated them with a hypothyroid-inducing agent and varying doses of thiamine over seven weeks.

The results were promising—thiamine improved memory in rats as evidenced by better performance in timed tests. Specifically, higher doses of thiamine led to increased memory retention and reduced oxidative stress. This suggests that thiamine could be a beneficial supplement for addressing memory issues related to hypothyroidism.
Read More
8
Vitamin B benefits hypothyroidism treatment
We aimed to explore how B vitamins, including pyridoxine, betaine, folic acid, and cyanocobalamin, can correct homocysteine metabolism disrupted by hypothyroidism. By studying experimental rats treated for prolonged periods, we found that hypothyroidism severely reduced the activity of key enzymes involved in methylation, which in turn raised homocysteine levels—linked to heart disease risk.

Our findings indicate that B vitamins have a promising potential to lower these harmful homocysteine levels and could help prevent complications like endothelial dysfunction in hypothyroid patients.
Read More
7
Vitamin B12 deficiency linked to hypothyroidism
We explored the connection between vitamin B12 levels and hypothyroidism in a study involving 100 patients. A significant 68% of these patients were found to be vitamin B12 deficient, with a notable correlation to the presence of anti TPO and anti Thyroglobulin antibodies.

This suggests that vitamin B12 may play a role in the symptoms experienced by hypothyroid individuals, especially since thyroid hormones influence the production of red blood cells. While supplementation could potentially help alleviate these symptoms, further research is essential to confirm its effectiveness in routine treatment.
Read More
We examined the effects of Myo-inositol on autoimmune thyroiditis and hypothyroidism. Clinical studies indicated that combining Myo-inositol with seleniomethionine significantly reduced TSH levels in patients with subclinical hypothyroidism.

This treatment not only lowered TSH but also reduced antithyroid autoantibodies, suggesting a positive immune-modulatory effect. However, further research with larger populations is needed to better understand how this treatment impacts overall quality of life and to investigate the underlying mechanisms involved.
Read More

User Reviews

USERS' SCORE
Good
Based on 7 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Metabolism improvement
11 people found this helpful
I take this B vitamin supplement daily after breakfast as I have hypothyroidism and experience a low metabolism. It's a safe product due to its modest dosage. I've noticed that my metabolism improves, making my body feel more active, enhancing brain circulation, and alleviating my depression. I highly recommend it.
Read More
9
Repeat purchase
I continually repurchase this excellent B complex and folate supplement for my thyroid issues, including hypothyroidism and Hashimoto's.
Read More
8
Iron assimilation support
This vitamin B supplement is beneficial for iron assimilation, nerve endings, and more, especially with my hypothyroidism. Its effectiveness gives me confidence to recommend it.
Read More
8
Health improvement
I started taking this B complex due to various health issues, including hypothyroidism and significant vitamin deficiencies. So far, I’ve experienced no side effects, and I've noticed improvements in waking up and staying alert throughout the day.
Read More
8
B12 deficiency tackled
I take this B vitamin supplement for my hypothyroidism and chronic B12 deficiency. I chose it for its active B12 content and the other essential vitamins that accompany it.
Read More

Frequently Asked Questions

9
Metabolism improvement
11 people found this helpful
I take this B vitamin supplement daily after breakfast as I have hypothyroidism and experience a low metabolism. It's a safe product due to its modest dosage. I've noticed that my metabolism improves, making my body feel more active, enhancing brain circulation, and alleviating my depression. I highly recommend it.
8
Health improvement
I started taking this B complex due to various health issues, including hypothyroidism and significant vitamin deficiencies. So far, I’ve experienced no side effects, and I've noticed improvements in waking up and staying alert throughout the day.
9
Repeat purchase
I continually repurchase this excellent B complex and folate supplement for my thyroid issues, including hypothyroidism and Hashimoto's.
8
B12 deficiency tackled
I take this B vitamin supplement for my hypothyroidism and chronic B12 deficiency. I chose it for its active B12 content and the other essential vitamins that accompany it.
8
Iron assimilation support
This vitamin B supplement is beneficial for iron assimilation, nerve endings, and more, especially with my hypothyroidism. Its effectiveness gives me confidence to recommend it.
7.5
Helpful for patients
As a patient with Hashimoto's hypothyroidism, I've found that active B vitamins support those with nutritional deficiencies. I’ve been taking this supplement and it works well for me.
9
Thiamine enhances memory in hypothyroidism
We explored the impact of thiamine (Vitamin B1) on memory and learning in rats with hypothyroidism. In a study involving 50 young rats, we treated them with a hypothyroid-inducing agent and varying doses of thiamine over seven weeks.

The results were promising—thiamine improved memory in rats as evidenced by better performance in timed tests. Specifically, higher doses of thiamine led to increased memory retention and reduced oxidative stress. This suggests that thiamine could be a beneficial supplement for addressing memory issues related to hypothyroidism.
7
Vitamin B12 deficiency linked to hypothyroidism
We explored the connection between vitamin B12 levels and hypothyroidism in a study involving 100 patients. A significant 68% of these patients were found to be vitamin B12 deficient, with a notable correlation to the presence of anti TPO and anti Thyroglobulin antibodies.

This suggests that vitamin B12 may play a role in the symptoms experienced by hypothyroid individuals, especially since thyroid hormones influence the production of red blood cells. While supplementation could potentially help alleviate these symptoms, further research is essential to confirm its effectiveness in routine treatment.
8
Vitamin B benefits hypothyroidism treatment
We aimed to explore how B vitamins, including pyridoxine, betaine, folic acid, and cyanocobalamin, can correct homocysteine metabolism disrupted by hypothyroidism. By studying experimental rats treated for prolonged periods, we found that hypothyroidism severely reduced the activity of key enzymes involved in methylation, which in turn raised homocysteine levels—linked to heart disease risk.

Our findings indicate that B vitamins have a promising potential to lower these harmful homocysteine levels and could help prevent complications like endothelial dysfunction in hypothyroid patients.
We examined the effects of Myo-inositol on autoimmune thyroiditis and hypothyroidism. Clinical studies indicated that combining Myo-inositol with seleniomethionine significantly reduced TSH levels in patients with subclinical hypothyroidism.

This treatment not only lowered TSH but also reduced antithyroid autoantibodies, suggesting a positive immune-modulatory effect. However, further research with larger populations is needed to better understand how this treatment impacts overall quality of life and to investigate the underlying mechanisms involved.

References

  1. Saberi R, Mirazi N, Amirahmadi S, Darbandi ZK, Vafaee F, et al. Ameliorative effects of thiamin on learning behavior and memory dysfunction in a rat model of hypothyroidism: implication of oxidative stress and acetylcholinesterase. Metab Brain Dis. 2023;38:2603. doi:10.1007/s11011-023-01317-0
  2. Chatterjee T, Gupta R, Choudhary S. A Study on Vitamin B12 Levels in Hypothyroid Patients Presenting to a Tertiary Care Teaching Hospital. J Assoc Physicians India. 2023;71:1.
  3. Nechyporuk V, Korda M, Pentiuk L, Dmytrenko I, Bulko I. The impact of B vitamins on the functioning of methylation cycle in the liver and the kidneys of hyper- and hypothyroid rats. Pol Merkur Lekarski. 2020;48:55.
  4. Fallahi P, Ferrari SM, Elia G, Ragusa F, Paparo SR, et al. Myo-inositol in autoimmune thyroiditis, and hypothyroidism. Rev Endocr Metab Disord. 2018;19:349. doi:10.1007/s11154-018-9477-9
image