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SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 36 Reviews
8.8
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Alpha-Lipoic acid
300 mg
†
Benfotiamine
150 mg
†
Top Medical Research Studies
8
Alpha-lipoic acid enhances wound healing
Lipoic acid improves wound healing through its immunomodulatory and anti-inflammatory effects in a diabetic mouse model.
Directly addresses diabetes treatment
We aimed to understand how alpha-lipoic acid (LA) affects wound healing in diabetic conditions. The study involved five groups of mice: healthy controls, wounded healthy mice, wounded diabetic mice, and two groups of wounded diabetic mice treated with different doses of LA for 14 days.
Our findings indicated that LA plays a significant role in improving the healing process. It works by balancing the levels of anti-inflammatory and pro-inflammatory factors that are essential for wound recovery. Specifically, we saw effects on various immune cell types that are vital for healing, indicating that LA may help to enhance recovery in diabetic wounds.
This study highlights the potential of LA as a supportive treatment option for wound healing in diabetic patients, ultimately aiming to reduce the risk of infections and improve overall recovery from injuries.
Our findings indicated that LA plays a significant role in improving the healing process. It works by balancing the levels of anti-inflammatory and pro-inflammatory factors that are essential for wound recovery. Specifically, we saw effects on various immune cell types that are vital for healing, indicating that LA may help to enhance recovery in diabetic wounds.
This study highlights the potential of LA as a supportive treatment option for wound healing in diabetic patients, ultimately aiming to reduce the risk of infections and improve overall recovery from injuries.
Read More
7
Alpha-Lipoic Acid reduces AGEs
Alpha-Lipoic Acid Treatment Reduces the Levels of Advanced End Glycation Products in Type 2 Diabetes Patients with Neuropathy.
Direct effect on diabetes treatment
We explored the potential benefits of alpha-lipoic acid (ALA) for those with type 2 diabetes (T2DM) and nerve complications, known as neuropathy. In our study, we focused on how ALA affects advanced end glycation products (AGEs), which are harmful compounds that can worsen the condition by damaging blood vessels and nerve tissues.
Our six-month intervention involved 54 T2DM patients with neuropathy who continued their prescribed medications while taking 600 mg of ALA daily. We contrasted their results with a control group of 24 matched patients without neuropathy.
We observed that ALA treatment significantly reduced the levels of AGEs, demonstrating its efficacy in lowering these harmful substances in individuals with diabetes (from 11.89 to 10.95 AU/μg). However, we noted that ALA did not influence other markers like soluble AGE receptor (sRAGE) levels or the AGEs/sRAGE ratio.
Additionally, we found correlations indicating that as AGEs decreased, improvements were noted in nerve function and other health markers. Overall, results suggest that ALA could be a beneficial treatment option for improving diabetic neuropathy and enhancing endothelial function, although it doesn't isolate its benefits from other existing diabetes medications.
Our six-month intervention involved 54 T2DM patients with neuropathy who continued their prescribed medications while taking 600 mg of ALA daily. We contrasted their results with a control group of 24 matched patients without neuropathy.
We observed that ALA treatment significantly reduced the levels of AGEs, demonstrating its efficacy in lowering these harmful substances in individuals with diabetes (from 11.89 to 10.95 AU/μg). However, we noted that ALA did not influence other markers like soluble AGE receptor (sRAGE) levels or the AGEs/sRAGE ratio.
Additionally, we found correlations indicating that as AGEs decreased, improvements were noted in nerve function and other health markers. Overall, results suggest that ALA could be a beneficial treatment option for improving diabetic neuropathy and enhancing endothelial function, although it doesn't isolate its benefits from other existing diabetes medications.
Read More
8
Alpha-lipoic acid enhances wound healing
Multifunctional hyaluronic acid microneedle patch enhances diabetic wound healing in diabetic infections.
Combines LA with peptide treatment.
We set out to explore how alpha-lipoic acid (LA) could help in the healing of diabetic wounds, which often struggle to heal due to a mix of factors like high blood sugar and infections. In our investigation, we combined LA with a specialized peptide using a unique self-assembly process that didn’t require extra help from outside sources.
This new combination was then placed into a microneedle patch made from hyaluronic acid (HA), allowing for a steady release of LA. We found that this patch was effective in fighting off harmful bacteria such as S. aureus and E. coli, which are common culprits in infections.
Furthermore, we observed that the sustained release of LA not only reduced harmful reactive oxygen species but also encouraged helpful immune responses and new blood vessel formation. This indicates a considerable improvement in tissue regeneration for wounds in diabetic patients. Overall, our findings suggest this multifunctional microneedle approach could significantly enhance healing in diabetic skin infections and showcases the considerable potential of combining LA in innovative treatment strategies.
This new combination was then placed into a microneedle patch made from hyaluronic acid (HA), allowing for a steady release of LA. We found that this patch was effective in fighting off harmful bacteria such as S. aureus and E. coli, which are common culprits in infections.
Furthermore, we observed that the sustained release of LA not only reduced harmful reactive oxygen species but also encouraged helpful immune responses and new blood vessel formation. This indicates a considerable improvement in tissue regeneration for wounds in diabetic patients. Overall, our findings suggest this multifunctional microneedle approach could significantly enhance healing in diabetic skin infections and showcases the considerable potential of combining LA in innovative treatment strategies.
Read More
Most Useful Reviews
9.5
Improved memory function
As I aged, I noticed my memory declining. Checking my thiamine levels showed they were low, especially on strict diets. Since taking Benfotiamine, I’ve experienced improvements in memory, sleep, and reduced irritability, making it easier to manage my diabetes. I suggest taking this complex as it also protects skin health.
Read More
9.5
Better blood glucose
After just one week of taking the Benfotiamine and alpha-lipoic acid, my blood glucose levels improved drastically. I also noticed that my cold feet sensation diminished, indicating better vascular function. I will continue using this product.
Read More
9.5
Reduced sugar spikes
Diagnosed with pre-diabetes, I stopped Metformin due to stomach issues. These supplements have alleviated the burning sensation in my feet and helped maintain balanced sugar levels even with higher carbohydrate intake. I’m thankful for this product.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
8
Alpha-lipoic acid enhances wound healing
Lipoic acid improves wound healing through its immunomodulatory and anti-inflammatory effects in a diabetic mouse model.
Directly addresses diabetes treatment
We aimed to understand how alpha-lipoic acid (LA) affects wound healing in diabetic conditions. The study involved five groups of mice: healthy controls, wounded healthy mice, wounded diabetic mice, and two groups of wounded diabetic mice treated with different doses of LA for 14 days.
Our findings indicated that LA plays a significant role in improving the healing process. It works by balancing the levels of anti-inflammatory and pro-inflammatory factors that are essential for wound recovery. Specifically, we saw effects on various immune cell types that are vital for healing, indicating that LA may help to enhance recovery in diabetic wounds.
This study highlights the potential of LA as a supportive treatment option for wound healing in diabetic patients, ultimately aiming to reduce the risk of infections and improve overall recovery from injuries.
Our findings indicated that LA plays a significant role in improving the healing process. It works by balancing the levels of anti-inflammatory and pro-inflammatory factors that are essential for wound recovery. Specifically, we saw effects on various immune cell types that are vital for healing, indicating that LA may help to enhance recovery in diabetic wounds.
This study highlights the potential of LA as a supportive treatment option for wound healing in diabetic patients, ultimately aiming to reduce the risk of infections and improve overall recovery from injuries.
Read More
8
Alpha-lipoic acid enhances wound healing
Multifunctional hyaluronic acid microneedle patch enhances diabetic wound healing in diabetic infections.
Combines LA with peptide treatment.
We set out to explore how alpha-lipoic acid (LA) could help in the healing of diabetic wounds, which often struggle to heal due to a mix of factors like high blood sugar and infections. In our investigation, we combined LA with a specialized peptide using a unique self-assembly process that didn’t require extra help from outside sources.
This new combination was then placed into a microneedle patch made from hyaluronic acid (HA), allowing for a steady release of LA. We found that this patch was effective in fighting off harmful bacteria such as S. aureus and E. coli, which are common culprits in infections.
Furthermore, we observed that the sustained release of LA not only reduced harmful reactive oxygen species but also encouraged helpful immune responses and new blood vessel formation. This indicates a considerable improvement in tissue regeneration for wounds in diabetic patients. Overall, our findings suggest this multifunctional microneedle approach could significantly enhance healing in diabetic skin infections and showcases the considerable potential of combining LA in innovative treatment strategies.
This new combination was then placed into a microneedle patch made from hyaluronic acid (HA), allowing for a steady release of LA. We found that this patch was effective in fighting off harmful bacteria such as S. aureus and E. coli, which are common culprits in infections.
Furthermore, we observed that the sustained release of LA not only reduced harmful reactive oxygen species but also encouraged helpful immune responses and new blood vessel formation. This indicates a considerable improvement in tissue regeneration for wounds in diabetic patients. Overall, our findings suggest this multifunctional microneedle approach could significantly enhance healing in diabetic skin infections and showcases the considerable potential of combining LA in innovative treatment strategies.
Read More
7
Alpha-Lipoic Acid reduces AGEs
Alpha-Lipoic Acid Treatment Reduces the Levels of Advanced End Glycation Products in Type 2 Diabetes Patients with Neuropathy.
Direct effect on diabetes treatment
We explored the potential benefits of alpha-lipoic acid (ALA) for those with type 2 diabetes (T2DM) and nerve complications, known as neuropathy. In our study, we focused on how ALA affects advanced end glycation products (AGEs), which are harmful compounds that can worsen the condition by damaging blood vessels and nerve tissues.
Our six-month intervention involved 54 T2DM patients with neuropathy who continued their prescribed medications while taking 600 mg of ALA daily. We contrasted their results with a control group of 24 matched patients without neuropathy.
We observed that ALA treatment significantly reduced the levels of AGEs, demonstrating its efficacy in lowering these harmful substances in individuals with diabetes (from 11.89 to 10.95 AU/μg). However, we noted that ALA did not influence other markers like soluble AGE receptor (sRAGE) levels or the AGEs/sRAGE ratio.
Additionally, we found correlations indicating that as AGEs decreased, improvements were noted in nerve function and other health markers. Overall, results suggest that ALA could be a beneficial treatment option for improving diabetic neuropathy and enhancing endothelial function, although it doesn't isolate its benefits from other existing diabetes medications.
Our six-month intervention involved 54 T2DM patients with neuropathy who continued their prescribed medications while taking 600 mg of ALA daily. We contrasted their results with a control group of 24 matched patients without neuropathy.
We observed that ALA treatment significantly reduced the levels of AGEs, demonstrating its efficacy in lowering these harmful substances in individuals with diabetes (from 11.89 to 10.95 AU/μg). However, we noted that ALA did not influence other markers like soluble AGE receptor (sRAGE) levels or the AGEs/sRAGE ratio.
Additionally, we found correlations indicating that as AGEs decreased, improvements were noted in nerve function and other health markers. Overall, results suggest that ALA could be a beneficial treatment option for improving diabetic neuropathy and enhancing endothelial function, although it doesn't isolate its benefits from other existing diabetes medications.
Read More
User Reviews
USERS' SCORE
Good
Based on 36 Reviews
8.8
10
Normalised blood sugar
Struggling with high blood sugar, I started this product after a friend's recommendation. I'm thrilled that my levels returned to normal after two months. The quality is commendable, and it's easy to swallow.
9.5
Improved memory function
As I aged, I noticed my memory declining. Checking my thiamine levels showed they were low, especially on strict diets. Since taking Benfotiamine, I’ve experienced improvements in memory, sleep, and reduced irritability, making it easier to manage my diabetes. I suggest taking this complex as it also protects skin health.
Read More
9.5
Better blood glucose
After just one week of taking the Benfotiamine and alpha-lipoic acid, my blood glucose levels improved drastically. I also noticed that my cold feet sensation diminished, indicating better vascular function. I will continue using this product.
9.5
Cost-effective supplement
This is the only product that combines both Benfotiamine and ALA, saving me money. Both ingredients greatly assist with diabetes management. I find this product effective and affordable.
9.5
Reduced sugar spikes
Diagnosed with pre-diabetes, I stopped Metformin due to stomach issues. These supplements have alleviated the burning sensation in my feet and helped maintain balanced sugar levels even with higher carbohydrate intake. I’m thankful for this product.
