Last update
5/7/2026
Reviewed By
Infographics
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Moderately Good
Based on 18 Reviews
7.2
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Vitamin C (as ascorbic acid)
40 mg
44%
Thiamin (as thiamin HCl)
60 mg
5000%
Riboflavin (as riboflavin and riboflavin-5-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
50 mg
313%
Vitamin B6 (from pyridoxine HCl and pyridoxal-5-phosphate)
50 mg
2941%
Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt) (Quatrefolic®)
400 mcg DFE
100%
Vitamin B12 (as methylcobalamin)
1000 mcg
41677%
Biotin
600 mcg
2000%
Pantothenic Acid (as d-calcium pantothenate)
100 mg
2000%
Top Medical Research Studies
9
We aimed to evaluate how a panthenol-enriched mask, specifically La Roche-Posay Mask Pro, performs in improving skin barriers for different types, such as dry sensitive, oily sensitive, and oily acne-prone skin.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Read More
7
A split-face study on 20 acne patients compared two treatments applied to opposite sides of the face. The right side received four intense pulsed light (IPL) sessions spaced two weeks apart, while the left side received topical nicotinamide 4% (vitamin B3) cream applied twice daily for two months.
Both treatments significantly improved inflammatory acne lesions. However, IPL delivered noticeably better results than the nicotinamide cream, with patients expressing greater satisfaction with the light-based approach. The findings suggest IPL is a safe and effective option for mild to moderate acne, particularly when other systemic treatments aren't suitable.
Both treatments significantly improved inflammatory acne lesions. However, IPL delivered noticeably better results than the nicotinamide cream, with patients expressing greater satisfaction with the light-based approach. The findings suggest IPL is a safe and effective option for mild to moderate acne, particularly when other systemic treatments aren't suitable.
Read More
Most Useful Reviews
0
Increased skin issues
6 people found this helpful
Caused acne, boils, headaches, and migraines. Unfortunately, Doctor's Best includes excessive amounts of B12, niacin, and biotin, which I believe is the issue as I experienced severe headaches and acne that left scars on my face, back, and arms. After two months of confusion, I realised the B complex was the culprit. Upon stopping, the flushing ceased and my headaches diminished. I recommend Doctor's Best to reduce certain vitamins substantially.
Read More
8
Improved skin condition
2 people found this helpful
A decent complex of B vitamins prescribed by my doctor. A deficiency in B vitamins affects the nervous system and external appearance. My skin condition improved significantly, including irritation and acne, after taking these vitamins, which I can confidently say are effective.
Read More
9
Reduced acne visibly
1 people found this helpful
Nice complex. B vitamins aid in several ways, particularly on the skin, where rashes and acne noticeably decrease and even disappear. I feel more energetic as well.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
- All Researches
9
We aimed to evaluate how a panthenol-enriched mask, specifically La Roche-Posay Mask Pro, performs in improving skin barriers for different types, such as dry sensitive, oily sensitive, and oily acne-prone skin.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Read More
7
A split-face study on 20 acne patients compared two treatments applied to opposite sides of the face. The right side received four intense pulsed light (IPL) sessions spaced two weeks apart, while the left side received topical nicotinamide 4% (vitamin B3) cream applied twice daily for two months.
Both treatments significantly improved inflammatory acne lesions. However, IPL delivered noticeably better results than the nicotinamide cream, with patients expressing greater satisfaction with the light-based approach. The findings suggest IPL is a safe and effective option for mild to moderate acne, particularly when other systemic treatments aren't suitable.
Both treatments significantly improved inflammatory acne lesions. However, IPL delivered noticeably better results than the nicotinamide cream, with patients expressing greater satisfaction with the light-based approach. The findings suggest IPL is a safe and effective option for mild to moderate acne, particularly when other systemic treatments aren't suitable.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 18 Reviews
7.2
- All Reviews
- Positive Reviews
- Negative Reviews
0
Increased skin issues
6 people found this helpful
Caused acne, boils, headaches, and migraines. Unfortunately, Doctor's Best includes excessive amounts of B12, niacin, and biotin, which I believe is the issue as I experienced severe headaches and acne that left scars on my face, back, and arms. After two months of confusion, I realised the B complex was the culprit. Upon stopping, the flushing ceased and my headaches diminished. I recommend Doctor's Best to reduce certain vitamins substantially.
Read More
8
Improved skin condition
2 people found this helpful
A decent complex of B vitamins prescribed by my doctor. A deficiency in B vitamins affects the nervous system and external appearance. My skin condition improved significantly, including irritation and acne, after taking these vitamins, which I can confidently say are effective.
Read More
9
Reduced acne visibly
1 people found this helpful
Nice complex. B vitamins aid in several ways, particularly on the skin, where rashes and acne noticeably decrease and even disappear. I feel more energetic as well.
Read More
10
Acne-free skin
The packaging quality is acceptable, with a blister pack included. The result is that my acne has disappeared, my skin is free of inflammation, and I feel less anxious.
Read More
9
Suitable for acne
This B vitamin supplement is very suitable for those with recurring acne, potentially due to a deficiency. The effect is strong, beneficial for the nervous system, and the quality is assured.
Read More
Frequently Asked Questions
9
Acne gone
The best B vitamins! Fantastic quality and value. After a month of use, my skin is substantially clearer, and the acne has disappeared, which was a key reason for my purchase.
7
Clearer skin observable
After two months, prescribed by my nutriciologist for acne clearance, I've noted that my skin has significantly improved. However, be sure to clear up your diet; don't rely solely on the supplements.
8
Effective acne control
I purchased this alongside zinc tablets for acne control. My doctor advised me to take the vitamin B complex with zinc to reduce facial oil and acne. After using it for a while, I've found it effective, although I experienced a yellow urine issue post-consumption.
9
Highly recommended
Since I started taking this, I haven't suffered from acne. It influences both lipid and carbohydrate metabolism. Although it isn't cheap, I recommend frequent use if you're dealing with acne.
7
Effective for acne
A very good medication. When combined with others for acne treatment, it has shown positive results.
8
Reduced forehead acne
Taking one pill a day provides me with energy! The acne on my children's foreheads has significantly reduced.
9
We aimed to evaluate how a panthenol-enriched mask, specifically La Roche-Posay Mask Pro, performs in improving skin barriers for different types, such as dry sensitive, oily sensitive, and oily acne-prone skin.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
References
- Zhang X, Tao H, Deng Y, He X, Zhang Z, et al. Efficacy and safety of a panthenol-enriched mask for individuals with distinct impaired skin barrier subtypes. J Cosmet Dermatol. 2024;23:2109. 10.1111/jocd.16231
- Al-Sharnoby HA, Al-Bakary RH, Nassar SO, Mesbah RAM. The Efficacy of Intense Pulsed Light Versus Topical Nicotinamide 4% in Treatment of Acne Vulgaris. Photodermatol Photoimmunol Photomed. 2025;41:e70025. 10.1111/phpp.70025
