Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
USERS' SCORE
Good
Based on 7 Reviews
8.8
Supplement Facts
Serving Size:  1 Veggie Capsule
Amount Per Serving
%DV
Vitamin C (as ascorbic acid)
40 mg
44%
Thiamin (as thiamin HCl)
60 mg
5000%
Riboflavin (as riboflavin and riboflavin-5-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
50 mg
313%
Vitamin B6 (from pyridoxine HCl and pyridoxal-5-phosphate)
50 mg
2941%
Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt) (Quatrefolic®)
400 mcg DFE
100%
Vitamin B12 (as methylcobalamin)
1000 mcg
41677%
Biotin
600 mcg
2000%
Pantothenic Acid (as d-calcium pantothenate)
100 mg
2000%

Top Medical Research Studies

9
Thiamine enhances memory in hypothyroidism
We explored the impact of thiamine (Vitamin B1) on memory and learning in rats with hypothyroidism. In a study involving 50 young rats, we treated them with a hypothyroid-inducing agent and varying doses of thiamine over seven weeks.

The results were promising—thiamine improved memory in rats as evidenced by better performance in timed tests. Specifically, higher doses of thiamine led to increased memory retention and reduced oxidative stress. This suggests that thiamine could be a beneficial supplement for addressing memory issues related to hypothyroidism.
Read More
8
Vitamin B benefits hypothyroidism treatment
We aimed to explore how B vitamins, including pyridoxine, betaine, folic acid, and cyanocobalamin, can correct homocysteine metabolism disrupted by hypothyroidism. By studying experimental rats treated for prolonged periods, we found that hypothyroidism severely reduced the activity of key enzymes involved in methylation, which in turn raised homocysteine levels—linked to heart disease risk.

Our findings indicate that B vitamins have a promising potential to lower these harmful homocysteine levels and could help prevent complications like endothelial dysfunction in hypothyroid patients.
Read More
7
Vitamin B12 deficiency linked to hypothyroidism
We explored the connection between vitamin B12 levels and hypothyroidism in a study involving 100 patients. A significant 68% of these patients were found to be vitamin B12 deficient, with a notable correlation to the presence of anti TPO and anti Thyroglobulin antibodies.

This suggests that vitamin B12 may play a role in the symptoms experienced by hypothyroid individuals, especially since thyroid hormones influence the production of red blood cells. While supplementation could potentially help alleviate these symptoms, further research is essential to confirm its effectiveness in routine treatment.
Read More

Most Useful Reviews

9.5
Metabolism improvement
I take this B vitamin supplement daily after breakfast as I have hypothyroidism and experience a low metabolism. It's a safe product due to its modest dosage. I've noticed that my metabolism improves, making my body feel more active, enhancing brain circulation, and alleviating my depression. I highly recommend it.
Read More
9.5
Repeat purchase
I continually repurchase this excellent B complex and folate supplement for my thyroid issues, including hypothyroidism and Hashimoto's.
Read More
9
Iron assimilation support
This vitamin B supplement is beneficial for iron assimilation, nerve endings, and more, especially with my hypothyroidism. Its effectiveness gives me confidence to recommend it.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
  • All Researches
9
Thiamine enhances memory in hypothyroidism
We explored the impact of thiamine (Vitamin B1) on memory and learning in rats with hypothyroidism. In a study involving 50 young rats, we treated them with a hypothyroid-inducing agent and varying doses of thiamine over seven weeks.

The results were promising—thiamine improved memory in rats as evidenced by better performance in timed tests. Specifically, higher doses of thiamine led to increased memory retention and reduced oxidative stress. This suggests that thiamine could be a beneficial supplement for addressing memory issues related to hypothyroidism.
Read More
8
Vitamin B benefits hypothyroidism treatment
We aimed to explore how B vitamins, including pyridoxine, betaine, folic acid, and cyanocobalamin, can correct homocysteine metabolism disrupted by hypothyroidism. By studying experimental rats treated for prolonged periods, we found that hypothyroidism severely reduced the activity of key enzymes involved in methylation, which in turn raised homocysteine levels—linked to heart disease risk.

Our findings indicate that B vitamins have a promising potential to lower these harmful homocysteine levels and could help prevent complications like endothelial dysfunction in hypothyroid patients.
Read More
7
Vitamin B12 deficiency linked to hypothyroidism
We explored the connection between vitamin B12 levels and hypothyroidism in a study involving 100 patients. A significant 68% of these patients were found to be vitamin B12 deficient, with a notable correlation to the presence of anti TPO and anti Thyroglobulin antibodies.

This suggests that vitamin B12 may play a role in the symptoms experienced by hypothyroid individuals, especially since thyroid hormones influence the production of red blood cells. While supplementation could potentially help alleviate these symptoms, further research is essential to confirm its effectiveness in routine treatment.
Read More
We examined the effects of Myo-inositol on autoimmune thyroiditis and hypothyroidism. Clinical studies indicated that combining Myo-inositol with seleniomethionine significantly reduced TSH levels in patients with subclinical hypothyroidism.

This treatment not only lowered TSH but also reduced antithyroid autoantibodies, suggesting a positive immune-modulatory effect. However, further research with larger populations is needed to better understand how this treatment impacts overall quality of life and to investigate the underlying mechanisms involved.
Read More

User Reviews

USERS' SCORE
Good
Based on 7 Reviews
8.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Metabolism improvement
I take this B vitamin supplement daily after breakfast as I have hypothyroidism and experience a low metabolism. It's a safe product due to its modest dosage. I've noticed that my metabolism improves, making my body feel more active, enhancing brain circulation, and alleviating my depression. I highly recommend it.
Read More
9.5
Repeat purchase
I continually repurchase this excellent B complex and folate supplement for my thyroid issues, including hypothyroidism and Hashimoto's.
Read More
9
Iron assimilation support
This vitamin B supplement is beneficial for iron assimilation, nerve endings, and more, especially with my hypothyroidism. Its effectiveness gives me confidence to recommend it.
Read More
9
Health improvement
I started taking this B complex due to various health issues, including hypothyroidism and significant vitamin deficiencies. So far, I’ve experienced no side effects, and I've noticed improvements in waking up and staying alert throughout the day.
Read More
9
B12 deficiency tackled
I take this B vitamin supplement for my hypothyroidism and chronic B12 deficiency. I chose it for its active B12 content and the other essential vitamins that accompany it.
Read More

Frequently Asked Questions

Hypothyroidism is a medical condition that occurs when the thyroid gland, a small butterfly-shaped gland located at the base of the neck, does not produce enough thyroid hormones. These hormones, mainly thyroxine (T4) and triiodothyronine (T3), play a critical role in regulating various bodily functions, including metabolism, energy production, and overall growth and development. When hormone levels drop, it can lead to a slow metabolism, weight gain, fatigue, depression, and a host of other symptoms that can significantly affect quality of life.

The condition can be caused by a variety of factors, including autoimmune diseases like Hashimoto's thyroiditis, certain medications, radiation treatment, or iodine deficiency. Diagnosis typically involves blood tests to check levels of thyroid-stimulating hormone (TSH) and thyroid hormones. Treatment primarily includes hormone replacement therapy, with synthetic thyroid hormones such as levothyroxine being the most common form of treatment. With proper management, individuals with hypothyroidism can lead normal, healthy lives by ensuring they receive the necessary hormones their bodies need to function optimally.

Vitamin B Complex refers to a group of water-soluble vitamins that play important roles in cell metabolism and overall health. This group typically includes eight essential vitamins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin). Each of these vitamins contributes uniquely to various bodily functions, such as energy production, red blood cell formation, and nervous system function. For instance, B12 and folate are crucial in preventing anemia, while B6 is vital for brain development and function.

Many people can obtain their daily requirements of B vitamins through a balanced diet that includes whole grains, meats, eggs, nuts, leafy greens, and dairy products. However, certain groups—like vegetarians, pregnant women, and older adults—may benefit from supplementation to meet their nutritional needs. It's important to consult with a healthcare professional before starting any supplement regimen, as excessive intake of certain B vitamins can lead to adverse effects. Overall, ensuring adequate intake of Vitamin B Complex is vital for maintaining energy levels and supporting overall health.

Based on user reviews, the time it takes to see results from a B vitamin supplement for hypothyroidism can vary among individuals. Many users report experiencing positive changes relatively quickly. For instance, one reviewer noted improvements in metabolism and overall energy levels soon after starting the supplement (Read Review). Others have also mentioned feeling more alert and active within a few days of beginning their regimen (Read Review).

Overall, while some users indicate they have felt benefits almost immediately, others may take longer to notice significant effects. Each person's body reacts differently to supplementation, particularly with conditions like hypothyroidism, which can complicate vitamin absorption and utilization. Therefore, while it's common to expect improvements within a few days to weeks, individual experiences can vary significantly. Consistency in taking the supplement is key, and monitoring one's body for changes can provide better insight into its effectiveness over time.

The research surrounding certain supplements for hypothyroidism shows promising potential but requires further exploration to establish definitive benefits. For instance, thiamine (Vitamin B1) has been shown to improve memory retention in hypothyroid rats, suggesting it may help with cognitive issues related to the condition [1]. Similarly, Vitamin B12 appears to play a significant role in alleviating symptoms of hypothyroidism, as a notable percentage of patients were found to be deficient in this vitamin [2]. This implies that supplementation might address some of the symptoms associated with hypothyroidism, though more studies are needed to confirm its routine use.

Additionally, the role of B vitamins overall in managing homocysteine levels presents another avenue for potential treatment, as these vitamins may help mitigate associated risks like heart disease [3]. Myo-inositol has also shown promise in reducing TSH levels and antithyroid antibodies when combined with seleniomethionine in clinical studies [4]. While there’s substantial early evidence supporting the use of these supplements in managing aspects of hypothyroidism, comprehensive research with larger sample sizes is essential to solidify their efficacy and therapeutic applications.

Based on user reviews, individuals have reported a variety of improvements in their symptoms related to hypothyroidism upon taking a B vitamin supplement. Many users noted enhanced metabolism and increased energy levels, which contributed to a more active lifestyle. For example, one reviewer shared that their metabolism improved significantly, leading to a boost in energy and enhanced mental clarity, which also helped alleviate feelings of depression (Read Review). Other users have echoed these sentiments, expressing that they felt more alert throughout the day and noticed substantial improvements in their overall well-being (Read Review).

Furthermore, several users emphasized the supplement's role in aiding nutritional absorption and providing essential vitamins, with some even continuing to repurchase it for its effectiveness in managing their thyroid-related conditions (Read Review). While experiences vary, it's clear that a number of users found relief from their symptoms through consistent use of the B vitamin supplement. It’s important to remember that individual results can differ, so monitoring your health conditions and talking with a healthcare provider is always recommended.

Based on user reviews, individuals with hypothyroidism have reported positive experiences when combining this B vitamin supplement with their existing health regimens. Many users noted that the supplement effectively supports their condition, enhancing metabolism and energy levels. For instance, one reviewer emphasized the benefit of the B vitamin for managing their hypothyroidism and mitigating chronic B12 deficiency, attributing improvements in their overall health directly to the product's active ingredients (Read Review). Another user specifically highlighted how the supplement aids in iron assimilation and nerve function, which are crucial for individuals managing thyroid issues (Read Review).

Several users also expressed their intent to continue using this B vitamin supplement alongside other therapies for hypothyroidism, indicating a sense of trust in its efficacy. One reported that the supplement is a consistent part of their regimen for hypothyroidism and Hashimoto's disease, showcasing its perceived importance in managing their condition (Read Review). Overall, the consensus seems to be that this supplement can effectively complement other treatments and contribute positively to managing symptoms associated with hypothyroidism.

Based on user reviews, it appears that several individuals with hypothyroidism find value in taking Vitamin B Complex supplements, reporting them to be effective in supporting their overall health and managing their symptoms. Users emphasize the importance of dosage, noting that they appreciate modest amounts, which they perceive as safe and beneficial. For instance, one user mentioned that a modest dosage helped improve their metabolism and alleviate feelings of depression (Read Review). Another user highlighted the effectiveness of the B complex in addressing nutritional deficiencies often associated with their condition (Read Review).

While specific dosage amounts were not frequently discussed in detail, users seem to be collectively satisfied with the results from daily usage of their chosen formulations. One user explicitly noted their reliance on the active B12 content in their chosen supplement, indicating that individuals might prioritize formulations that address their particular deficiencies (Read Review). Overall, user feedback suggests that finding the right B complex supplement, preferably with a balanced and moderate dosage, can positively impact those dealing with hypothyroidism.

9.5
Metabolism improvement
I take this B vitamin supplement daily after breakfast as I have hypothyroidism and experience a low metabolism. It's a safe product due to its modest dosage. I've noticed that my metabolism improves, making my body feel more active, enhancing brain circulation, and alleviating my depression. I highly recommend it.
9
Health improvement
I started taking this B complex due to various health issues, including hypothyroidism and significant vitamin deficiencies. So far, I’ve experienced no side effects, and I've noticed improvements in waking up and staying alert throughout the day.
9.5
Repeat purchase
I continually repurchase this excellent B complex and folate supplement for my thyroid issues, including hypothyroidism and Hashimoto's.
9
B12 deficiency tackled
I take this B vitamin supplement for my hypothyroidism and chronic B12 deficiency. I chose it for its active B12 content and the other essential vitamins that accompany it.
9
Iron assimilation support
This vitamin B supplement is beneficial for iron assimilation, nerve endings, and more, especially with my hypothyroidism. Its effectiveness gives me confidence to recommend it.
8.8
Helpful for patients
As a patient with Hashimoto's hypothyroidism, I've found that active B vitamins support those with nutritional deficiencies. I’ve been taking this supplement and it works well for me.
9
Thiamine enhances memory in hypothyroidism
We explored the impact of thiamine (Vitamin B1) on memory and learning in rats with hypothyroidism. In a study involving 50 young rats, we treated them with a hypothyroid-inducing agent and varying doses of thiamine over seven weeks.

The results were promising—thiamine improved memory in rats as evidenced by better performance in timed tests. Specifically, higher doses of thiamine led to increased memory retention and reduced oxidative stress. This suggests that thiamine could be a beneficial supplement for addressing memory issues related to hypothyroidism.
7
Vitamin B12 deficiency linked to hypothyroidism
We explored the connection between vitamin B12 levels and hypothyroidism in a study involving 100 patients. A significant 68% of these patients were found to be vitamin B12 deficient, with a notable correlation to the presence of anti TPO and anti Thyroglobulin antibodies.

This suggests that vitamin B12 may play a role in the symptoms experienced by hypothyroid individuals, especially since thyroid hormones influence the production of red blood cells. While supplementation could potentially help alleviate these symptoms, further research is essential to confirm its effectiveness in routine treatment.
8
Vitamin B benefits hypothyroidism treatment
We aimed to explore how B vitamins, including pyridoxine, betaine, folic acid, and cyanocobalamin, can correct homocysteine metabolism disrupted by hypothyroidism. By studying experimental rats treated for prolonged periods, we found that hypothyroidism severely reduced the activity of key enzymes involved in methylation, which in turn raised homocysteine levels—linked to heart disease risk.

Our findings indicate that B vitamins have a promising potential to lower these harmful homocysteine levels and could help prevent complications like endothelial dysfunction in hypothyroid patients.
We examined the effects of Myo-inositol on autoimmune thyroiditis and hypothyroidism. Clinical studies indicated that combining Myo-inositol with seleniomethionine significantly reduced TSH levels in patients with subclinical hypothyroidism.

This treatment not only lowered TSH but also reduced antithyroid autoantibodies, suggesting a positive immune-modulatory effect. However, further research with larger populations is needed to better understand how this treatment impacts overall quality of life and to investigate the underlying mechanisms involved.

References

  1. Saberi R, Mirazi N, Amirahmadi S, Darbandi ZK, Vafaee F, et al. Ameliorative effects of thiamin on learning behavior and memory dysfunction in a rat model of hypothyroidism: implication of oxidative stress and acetylcholinesterase. Metab Brain Dis. 2023;38:2603. doi:10.1007/s11011-023-01317-0
  2. Chatterjee T, Gupta R, Choudhary S. A Study on Vitamin B12 Levels in Hypothyroid Patients Presenting to a Tertiary Care Teaching Hospital. J Assoc Physicians India. 2023;71:1.
  3. Nechyporuk V, Korda M, Pentiuk L, Dmytrenko I, Bulko I. The impact of B vitamins on the functioning of methylation cycle in the liver and the kidneys of hyper- and hypothyroid rats. Pol Merkur Lekarski. 2020;48:55.
  4. Fallahi P, Ferrari SM, Elia G, Ragusa F, Paparo SR, et al. Myo-inositol in autoimmune thyroiditis, and hypothyroidism. Rev Endocr Metab Disord. 2018;19:349. doi:10.1007/s11154-018-9477-9
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