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Doctor's Best Glucosamine Chondroitin Msm with OptiMSM
SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
USERS' SCORE
Good
Based on 5 Reviews
8.7
Supplement Facts
Serving Size:  4 capsules
Amount Per Serving
%DV
Chloride (from glucosamine hydrochloride potassium sulfate)
170 mg 
7%
Sodium (from chondroitin sulfate sodium)
120 mg
5%
Potassium (from glucosamine hydrochloride potassium sulfate)
190 mg 
4%
GlucosamineHydrochloride Potassium Sulfate
1500 mg
Chondroitin sulfate Sodium
1200 mg
MSM (Methylsulfonylmethane)(OptiMSM®)
1000 mg

Top Medical Research Studies

9
MSM improves migraine management
Acute migraine medication adherence, migraine disability and patient satisfaction: A naturalistic daily diary study.
Strong relevance to migraine treatment
We aimed to understand how adherence to migraine-specific medications (MSMs) influences migraine-related disability and patient satisfaction. Over three months, 337 participants used daily electronic diaries to track their migraine experiences, including the medications they took and their satisfaction with these treatments.

It was insightful to see that participants took their acute medications on a staggering 96.5% of the days they recorded migraines. Among the medications used, MSMs were the most common at 58%, followed by over-the-counter analgesics and opiates/barbiturates. We found that people tended to reach for medication when their pain was mild most often.

Our analysis showed that when individuals used MSMs during mild pain, they experienced the least daily disability and reported the highest satisfaction with their medications. This implies that using MSMs earlier, especially at the onset of milder symptoms, can significantly improve a patient's overall experience with migraines.

In conclusion, our study highlights the benefits of starting treatment with MSMs for better outcomes in managing migraine-related challenges and achieving greater satisfaction with acute medication usage.
Read More
9
Erenumab reduces migraine medication use
Reduction in acute migraine-specific and non-specific medication use in patients treated with erenumab: post-hoc analyses of episodic and chronic migraine clinical trials.
Moderate relevance to MSM effects
We explored how treatment with erenumab affects the use of acute migraine medications. This study analyzed data from two large clinical trials involving nearly 1,600 participants suffering from episodic migraine (EM) and chronic migraine (CM). Patients received either erenumab or a placebo monthly for treatment, while they recorded their medication usage in an electronic diary.

Our findings highlighted that erenumab not only reduces the frequency of acute headaches but also leads to a significant decrease in the use of acute headache medications, particularly migraine-specific medications like triptans and ergots. This suggests that treating migraines with erenumab may help minimize the risk of over-reliance on acute medication, which can sometimes lead to adverse health situations, such as medication overuse headache.

Overall, the treatment with erenumab proves promising for anyone looking to manage their migraine efficiently, allowing patients to experience relief while reducing their dependency on other acute medications.
Read More

Most Useful Reviews

9.5
Reduces migraine frequency
GREAT It normalises sleep with regular intake of 2 capsules. It improves my migraines significantly. When the special effects begin, I take my usual pills, add extra magnesium, and the migraine fades within a couple of hours, compared to the previous half-day disruption. The frequency has also decreased alongside medicinal support. Regular magnesium intake eases PMS and periods, so I remain calmer, and I can even go a day without painkillers. Chronic pain in my nasopharynx hardly worsens. I also take omega-3, serrapeptase, and resveratrol, but I believe magnesium plays a role. Taking magnesium, lecithin, and protein has shown a genuine effect with collagen. I was pleasantly surprised. No allergies, rashes, or digestive issues. Quality is excellent with natural ingredients.
Read More
9.5
Stops migraines quickly
Great supplement! Excellent quality ingredients. The dosage and method of administration are clearly detailed on the package. It has a neutral taste and a reasonable size. The benefits become apparent quickly; my migraines and headaches vanish, and joint problems diminish. Glucosamine aids bone and joint issues at any age, enhancing cartilage and connective tissue health. This supplement is very good, and I intend to purchase more.
Read More
9.5
Helps with migraines
Great! It normalises sleep with a regular intake of 2 capsules, improving my migraines. When effects start, I take my usual pills along with magnesium, leading to migraines easing within a couple of hours. Previously, I was incapacitated for half a day. The frequency has also reduced, aided by medicinal support. Regular magnesium consumption eases PMS and menstruation, and I remain calm without painkillers. Chronic nasopharyngeal pain hardly worsens. I also take omega-3, serrapeptase, and resveratrol, and I feel magnesium has a significant impact. Drinking magnesium, lecithin, and protein truly enhances the benefits of oral collagen. I was astonished. No allergies, rashes, or stomach issues; the product is of high quality and natural.
Read More

Medical Researches

SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
9
Erenumab reduces migraine medication use
Reduction in acute migraine-specific and non-specific medication use in patients treated with erenumab: post-hoc analyses of episodic and chronic migraine clinical trials.
Moderate relevance to MSM effects
We explored how treatment with erenumab affects the use of acute migraine medications. This study analyzed data from two large clinical trials involving nearly 1,600 participants suffering from episodic migraine (EM) and chronic migraine (CM). Patients received either erenumab or a placebo monthly for treatment, while they recorded their medication usage in an electronic diary.

Our findings highlighted that erenumab not only reduces the frequency of acute headaches but also leads to a significant decrease in the use of acute headache medications, particularly migraine-specific medications like triptans and ergots. This suggests that treating migraines with erenumab may help minimize the risk of over-reliance on acute medication, which can sometimes lead to adverse health situations, such as medication overuse headache.

Overall, the treatment with erenumab proves promising for anyone looking to manage their migraine efficiently, allowing patients to experience relief while reducing their dependency on other acute medications.
Read More
9
MSM improves migraine management
Acute migraine medication adherence, migraine disability and patient satisfaction: A naturalistic daily diary study.
Strong relevance to migraine treatment
We aimed to understand how adherence to migraine-specific medications (MSMs) influences migraine-related disability and patient satisfaction. Over three months, 337 participants used daily electronic diaries to track their migraine experiences, including the medications they took and their satisfaction with these treatments.

It was insightful to see that participants took their acute medications on a staggering 96.5% of the days they recorded migraines. Among the medications used, MSMs were the most common at 58%, followed by over-the-counter analgesics and opiates/barbiturates. We found that people tended to reach for medication when their pain was mild most often.

Our analysis showed that when individuals used MSMs during mild pain, they experienced the least daily disability and reported the highest satisfaction with their medications. This implies that using MSMs earlier, especially at the onset of milder symptoms, can significantly improve a patient's overall experience with migraines.

In conclusion, our study highlights the benefits of starting treatment with MSMs for better outcomes in managing migraine-related challenges and achieving greater satisfaction with acute medication usage.
Read More

User Reviews

USERS' SCORE
Good
Based on 5 Reviews
8.7
9.5
Reduces migraine frequency
GREAT It normalises sleep with regular intake of 2 capsules. It improves my migraines significantly. When the special effects begin, I take my usual pills, add extra magnesium, and the migraine fades within a couple of hours, compared to the previous half-day disruption. The frequency has also decreased alongside medicinal support. Regular magnesium intake eases PMS and periods, so I remain calmer, and I can even go a day without painkillers. Chronic pain in my nasopharynx hardly worsens. I also take omega-3, serrapeptase, and resveratrol, but I believe magnesium plays a role. Taking magnesium, lecithin, and protein has shown a genuine effect with collagen. I was pleasantly surprised. No allergies, rashes, or digestive issues. Quality is excellent with natural ingredients.
Read More
9.5
Stops migraines quickly
Great supplement! Excellent quality ingredients. The dosage and method of administration are clearly detailed on the package. It has a neutral taste and a reasonable size. The benefits become apparent quickly; my migraines and headaches vanish, and joint problems diminish. Glucosamine aids bone and joint issues at any age, enhancing cartilage and connective tissue health. This supplement is very good, and I intend to purchase more.
Read More
9.5
Helps with migraines
Great! It normalises sleep with a regular intake of 2 capsules, improving my migraines. When effects start, I take my usual pills along with magnesium, leading to migraines easing within a couple of hours. Previously, I was incapacitated for half a day. The frequency has also reduced, aided by medicinal support. Regular magnesium consumption eases PMS and menstruation, and I remain calm without painkillers. Chronic nasopharyngeal pain hardly worsens. I also take omega-3, serrapeptase, and resveratrol, and I feel magnesium has a significant impact. Drinking magnesium, lecithin, and protein truly enhances the benefits of oral collagen. I was astonished. No allergies, rashes, or stomach issues; the product is of high quality and natural.
Read More
8.8
Relieves migraine pain
My mother-in-law experienced severe joint pain, particularly in her knees, due to menopause. As a nutritionist, I advised her against painkillers and ointments, prescribing this drug along with collagen (with vitamin C), vitamin D, MK7, and turmeric at higher doses due to deficiency. After 2 weeks, all pain disappeared. The same treatment applied to my mother, who suffered from hand pain. I prepped thoroughly, having prior vitamin D and MK-7. Boswellia and PEA effectively relieve joint inflammation and acute pain, also aiding migraines!
Read More
8
Fewer migraines experienced
Nice Complex! It works well! I initially purchased it for osteochondrosis and hernia. My health improved significantly while taking it. When I stopped, everything ached again (neck, back, low blood pressure). It effectively alleviated inflammation and pain, resulting in fewer migraines. Continued use seems necessary for best results.
Read More
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