Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 14 Reviews
8.7
Supplement Facts
Serving Size: 4 capsules
Amount Per Serving
%DV
Chloride (from glucosamine hydrochloride potassium sulfate)
170 mg
7%
Sodium (from chondroitin sulfate sodium)
120 mg
5%
Potassium (from glucosamine hydrochloride potassium sulfate)
190 mg
4%
GlucosamineHydrochloride Potassium Sulfate
1500 mg
†
Chondroitin sulfate Sodium
1200 mg
†
MSM (Methylsulfonylmethane)(OptiMSM®)
1000 mg
†
Top Medical Research Studies
8
We investigated how methylsulfonylmethane (MSM) interacts with bone morphogenetic protein 2 (BMP-2) to potentially enhance the differentiation of mesenchymal stem cells (MSCs) into osteoblasts, which are crucial for bone health. The study revealed that both MSM and BMP-2, when combined, lead to increased levels of certain proteins that aid in this process.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Read More
Most Useful Reviews
9.5
Slows osteoporosis progression
Doctor's Best Glucosamine, Chondroitin, and MSM is a remarkable tool for aiding cartilage health. It slows bone resorption and enhances calcium retention, promoting bone tissue repair and inhibiting cartilage degeneration. Its topical application can slow osteoporosis progression and stimulate regeneration in connective tissues. I highly recommend it for managing joint pain and enhancing the normal physiological processes!
Read More
9.5
Highly recommended effect
Osteoporosis, wonderful. For those suffering from osteoporosis, follow the instructions on the box when using. I highly recommend it; my mother has osteoporosis and has benefited, thank God.
Read More
9.5
Enhanced flexibility observed
I bought it for my elder who has osteoporosis and struggles to get up from sitting. After three months of use, he now can easily catch up with his children and move around with greater flexibility.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We investigated how methylsulfonylmethane (MSM) interacts with bone morphogenetic protein 2 (BMP-2) to potentially enhance the differentiation of mesenchymal stem cells (MSCs) into osteoblasts, which are crucial for bone health. The study revealed that both MSM and BMP-2, when combined, lead to increased levels of certain proteins that aid in this process.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Read More
User Reviews
USERS' SCORE
Good
Based on 14 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Slows osteoporosis progression
Doctor's Best Glucosamine, Chondroitin, and MSM is a remarkable tool for aiding cartilage health. It slows bone resorption and enhances calcium retention, promoting bone tissue repair and inhibiting cartilage degeneration. Its topical application can slow osteoporosis progression and stimulate regeneration in connective tissues. I highly recommend it for managing joint pain and enhancing the normal physiological processes!
Read More
9.5
Highly recommended effect
Osteoporosis, wonderful. For those suffering from osteoporosis, follow the instructions on the box when using. I highly recommend it; my mother has osteoporosis and has benefited, thank God.
Read More
9.5
Enhanced flexibility observed
I bought it for my elder who has osteoporosis and struggles to get up from sitting. After three months of use, he now can easily catch up with his children and move around with greater flexibility.
Read More
8.8
Supports joint health
Doctor's Best Glucosamine, Chondroitin & MSM supports joint and connective tissue health. It promotes healthy joints, lubricates them, and improves mobility. This formula is effective in treating arthrosis, arthritis, osteoporosis, and osteochondrosis. The effects are cumulative, so consistent use is important. I've noticed pain relief within the first week, and my joints feel lighter. Highly recommend for overall joint health!
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8.8
Tangible results noted
I give it to my 70-year-old mother, diagnosed with osteoporosis. After three weeks, she noticed tangible results! She drinks it for two months with a 1-2 month break.
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Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Kim DN, Joung YH, Darvin P, Kang DY, Sp N, et al. Methylsulfonylmethane enhances BMP‑2‑induced osteoblast differentiation in mesenchymal stem cells. Mol Med Rep. 2016;14:460. doi:10.3892/mmr.2016.5274
