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The results were telling. We discovered that nattokinase has protective effects against acute ischemic strokes and plays a significant role in promoting neurogenesis, which is the process of generating new brain cells. Through experiments conducted on rat models, we observed that nattokinase notably increases irisin levels in peripheral blood. Irisin is a protein that has emerged as an interesting player in enhancing cognitive functions.
By linking the increased levels of irisin to improved cognitive abilities, our findings suggest that nattokinase could be a promising therapy for those suffering from PSCI, positioning irisin as a potential target for treatment. Overall, our research highlights the exciting possibilities that nattokinase offers in the realm of stroke recovery and brain health.
Our observations revealed that NK treatment significantly reduced the size of brain injury and enhanced recovery from neurological issues. It also helped lower levels of harmful pro-inflammatory and coagulation substances while reducing oxidative stress markers in the affected brain area. These findings show NK’s potential in protecting the brain from the damaging effects of stroke.
Furthermore, we explored NK's protective properties in laboratory tests simulating neuron injury due to lack of oxygen and glucose. We found that it was effective in countering cell death across these models, working through various biological pathways. However, when we blocked NK's activity with a specific inhibitor, we noticed that its protective effects vanished, demonstrating that NK's enzymatic activity is crucial for its benefits.
Overall, this study highlights the multi-faceted protective role of nattokinase in brain injuries caused by ischemic events, confirming its potential as a therapeutic agent in stroke treatment.
After 60 days, both the Nattospes and control groups showed significant improvements in physical activities, blood pressure, and quality of life. While Nattospes demonstrated beneficial effects on stroke symptoms, it’s important to note that no adverse effects were reported.
The results suggest that Nattospes can safely support stroke recovery. These findings encourage further research into Nattospes as a potential supplement in cardiovascular disease management.
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Our observations revealed that NK treatment significantly reduced the size of brain injury and enhanced recovery from neurological issues. It also helped lower levels of harmful pro-inflammatory and coagulation substances while reducing oxidative stress markers in the affected brain area. These findings show NK’s potential in protecting the brain from the damaging effects of stroke.
Furthermore, we explored NK's protective properties in laboratory tests simulating neuron injury due to lack of oxygen and glucose. We found that it was effective in countering cell death across these models, working through various biological pathways. However, when we blocked NK's activity with a specific inhibitor, we noticed that its protective effects vanished, demonstrating that NK's enzymatic activity is crucial for its benefits.
Overall, this study highlights the multi-faceted protective role of nattokinase in brain injuries caused by ischemic events, confirming its potential as a therapeutic agent in stroke treatment.
While both treatments lowered cholesterol and triglyceride levels, statins achieved greater reductions. Interestingly, nattokinase raised good cholesterol levels, unlike statins. Our study suggests that nattokinase could be a promising alternative in managing atherosclerosis and reducing stroke risk.
The results were telling. We discovered that nattokinase has protective effects against acute ischemic strokes and plays a significant role in promoting neurogenesis, which is the process of generating new brain cells. Through experiments conducted on rat models, we observed that nattokinase notably increases irisin levels in peripheral blood. Irisin is a protein that has emerged as an interesting player in enhancing cognitive functions.
By linking the increased levels of irisin to improved cognitive abilities, our findings suggest that nattokinase could be a promising therapy for those suffering from PSCI, positioning irisin as a potential target for treatment. Overall, our research highlights the exciting possibilities that nattokinase offers in the realm of stroke recovery and brain health.
After 60 days, both the Nattospes and control groups showed significant improvements in physical activities, blood pressure, and quality of life. While Nattospes demonstrated beneficial effects on stroke symptoms, it’s important to note that no adverse effects were reported.
The results suggest that Nattospes can safely support stroke recovery. These findings encourage further research into Nattospes as a potential supplement in cardiovascular disease management.
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Frequently Asked Questions
A stroke occurs when the blood supply to a part of the brain is interrupted or reduced, preventing brain tissue from getting oxygen and nutrients. This can happen in two primary ways: an ischemic stroke, which occurs when a blood vessel supplying blood to the brain is obstructed, often due to a blood clot; and a hemorrhagic stroke, which occurs when a blood vessel in the brain bursts, leading to bleeding in or around the brain. The severity and outcome of a stroke can vary widely depending on the type, location, and amount of brain tissue affected, as well as the speed with which medical treatment is received.
Recognizing the symptoms of a stroke is crucial for prompt treatment and recovery. Common signs include sudden numbness or weakness in the face, arm, or leg, especially on one side of the body, confusion, trouble speaking or understanding speech, vision problems in one or both eyes, and difficulty walking, which may include dizziness or loss of balance coordination. The acronym FAST can help remember the key signs: Face drooping, Arm weakness, Speech difficulty, and Time to call emergency services. If you or someone you know exhibits these symptoms, it's vital to seek immediate medical attention, as timely intervention can significantly improve outcomes.
Nattokinase is an enzyme extracted from a traditional Japanese food called natto, which is made from fermented soybeans. This enzyme is thought to have potential health benefits, primarily for cardiovascular health. Nattokinase is believed to support the breakdown of fibrin in the blood, which can help improve circulation and reduce the risk of blood clot formation. As a dietary supplement, it is often marketed for its possible ability to promote healthy blood flow and cardiovascular function.
While some studies suggest that nattokinase may help reduce blood pressure and enhance overall heart health, research is still ongoing. As with any supplement, it is essential to consult with a healthcare professional before adding nattokinase to your regimen, especially if you are on blood-thinning medications or have underlying health conditions. Overall, while nattokinase might offer some intriguing health benefits, more comprehensive studies are needed to fully understand its efficacy and safety profile.
Based on user reviews, there seems to be a varied timeline when it comes to seeing results from the supplement for stroke recovery. Some users note that they have experienced significant improvements after making the switch from traditional prescription medications. One reviewer shared, "After starting this supplement, I stopped taking prescription medications and feel quite well," indicating a positive outcome shortly after starting the supplement (Read Review).
Another user mentioned purchasing the supplement for a family member, suggesting that many individuals consider these supplements a supportive choice for their loved ones post-stroke, due to the belief in the ingredients' benefits (Read Review). While specific timelines weren’t provided in the reviews, they indicate that users are optimistic about the supplement's impact relatively early in their use. As always, it is advisable to consult with a healthcare professional before making changes to treatment plans.
Recent studies suggest that the supplement nattokinase may provide significant benefits for stroke prevention and recovery. In one study, researchers found that nattokinase treatment reduced the size of brain injuries and improved neurological recovery in models of ischemic stroke (the basis of most types of strokes) [1]. This enzyme not only mitigated brain damage but also decreased harmful inflammation and oxidative stress in the brain, indicating its potential as a therapeutic agent in stroke management.
Further supporting its role in stroke recovery, another study found that nattokinase can enhance neurogenesis, the growth of new brain cells, and improve cognitive functions in patients recovering from strokes [2]. Additionally, a randomized controlled trial involving human participants demonstrated that Nattospes (a nattokinase supplement) improved various recovery metrics after stroke, showcasing its safety and efficacy [3]. These promising findings highlight nattokinase's potential as a valuable supplement for both stroke prevention and rehabilitation, although additional research is necessary to fully establish its efficacy and optimal usage in clinical settings.
Users have reported a range of benefits when using this supplement, particularly regarding improvements in post-stroke recovery. One user specifically shared their experience of stopping traditional prescription medications after starting the supplement, noting a significant improvement in well-being, as highlighted by their hematologist, who expressed satisfaction with the results (Read Review). This underscores a potential shift towards more natural support methods for individuals with vascular concerns.
Additionally, the choice to purchase the supplement for family members, as seen in one review, suggests that users believe strongly in the product's supportive role for stroke recovery. This buyer took the initiative after personal research on the product's ingredients, validating their efficacy for stroke-related issues (Read Review). Such anecdotal experiences indicate that many users are optimistic about the supplement's impact on their or their loved ones' health, although encouraging individual results can greatly differ.
Users report mixed experiences regarding the use of Nattokinase for treating strokes, often emphasizing the need for individualized dosing. One user shared that they had a successful transition from prescription blood thinners to Nattokinase after experiencing deep vein thrombosis and a stroke, expressing satisfaction with their improved well-being while highlighting the importance of consultation with healthcare providers for a safe transition (Read Review). Another user noted that they began purchasing Nattokinase for their godfather following his stroke, motivated by research indicating the supplement's potential benefits for stroke recovery (Read Review).
However, specific recommendations regarding the right dosage for Nattokinase in stroke treatment were not detailed in the reviews, indicating that users may rely on personal research or advice from healthcare professionals rather than a standardized dosage. This highlights the importance of discussing appropriate dosages with a doctor, as individual needs can vary significantly.
Our observations revealed that NK treatment significantly reduced the size of brain injury and enhanced recovery from neurological issues. It also helped lower levels of harmful pro-inflammatory and coagulation substances while reducing oxidative stress markers in the affected brain area. These findings show NK’s potential in protecting the brain from the damaging effects of stroke.
Furthermore, we explored NK's protective properties in laboratory tests simulating neuron injury due to lack of oxygen and glucose. We found that it was effective in countering cell death across these models, working through various biological pathways. However, when we blocked NK's activity with a specific inhibitor, we noticed that its protective effects vanished, demonstrating that NK's enzymatic activity is crucial for its benefits.
Overall, this study highlights the multi-faceted protective role of nattokinase in brain injuries caused by ischemic events, confirming its potential as a therapeutic agent in stroke treatment.
The results were telling. We discovered that nattokinase has protective effects against acute ischemic strokes and plays a significant role in promoting neurogenesis, which is the process of generating new brain cells. Through experiments conducted on rat models, we observed that nattokinase notably increases irisin levels in peripheral blood. Irisin is a protein that has emerged as an interesting player in enhancing cognitive functions.
By linking the increased levels of irisin to improved cognitive abilities, our findings suggest that nattokinase could be a promising therapy for those suffering from PSCI, positioning irisin as a potential target for treatment. Overall, our research highlights the exciting possibilities that nattokinase offers in the realm of stroke recovery and brain health.
After 60 days, both the Nattospes and control groups showed significant improvements in physical activities, blood pressure, and quality of life. While Nattospes demonstrated beneficial effects on stroke symptoms, it’s important to note that no adverse effects were reported.
The results suggest that Nattospes can safely support stroke recovery. These findings encourage further research into Nattospes as a potential supplement in cardiovascular disease management.
References
- Yang XY, Wang SL, Xue WC, Zhang YP, Li LL, et al. Nattokinase's Neuroprotective Mechanisms in Ischemic Stroke: Targeting Inflammation, Oxidative Stress, and Coagulation. Antioxid Redox Signal. 2025;42:228. doi:10.1089/ars.2023.0527
- Wu H, Zhang Q, Xu P, Chen J, Duan L, et al. Nattokinase Promotes Post-stroke Neurogenesis and Cognition Recovery via Increasing Circulating Irisin. J Agric Food Chem. 2023;71:11418. doi:10.1021/acs.jafc.2c08718
- Pham PT, Han B, Hoang BX. Nattospes as Effective and Safe Functional Supplements in Management of Stroke. J Med Food. 2020;23:879. doi:10.1089/jmf.2019.0183
- Ren NN, Chen HJ, Li Y, Mcgowan GW, Lin YG. [A clinical study on the effect of nattokinase on carotid artery atherosclerosis and hyperlipidaemia]. Zhonghua Yi Xue Za Zhi. 2017;97:2038. doi:10.3760/cma.j.issn.0376-2491.2017.26.005
