Supplement Facts
Serving Size: 1 Veggie Capsule
Serving Per Container: 90
Amount Per Serving
%DV
Nattokinase(from fibrinase enzyme)
2,000 FU**
†
The product is found useful for the following medical conditions
Common Cold details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 12 Reviews
8.6
9
Warm hands achieved
Most Useful Review
30 people found this helpful
Warm hands for the first time in my life! I began taking Nattokinase due to persistent cold hands and feet throughout my life, and this issue worsened with age. Other remedies like ginger and cayenne caused upset stomachs, but Nattokinase was gentler and more effective. After my first dose before bed, I woke with warm hands that lasted all day, even in winter. I slept with my arms uncovered as I felt unusually warm and typing was easier with warm fingers. One capsule daily suffices, and I've noticed improved sleep quality—quite unexpected! This nattokinase has significantly restored circulation to my hands and feet.
Back Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
Tumour pain relief
Most Useful Review
73 people found this helpful
Saved me from horrible fibroid tumour pain! Five months ago, I suffered from horrendous fibroid tumour pain that nearly drove me mad. My doctors offered only surgery, so I researched ways to shrink tumours. I began taking "Doctor's Best Best Serrapeptase (40,000 Units)," one tablet twice a day. For the next cycle, there was nothing. Now, five cycles in, the burning fibroid tumour pain has vanished. I believe the tumour has shrunk. I'm hesitant to stop taking it, fearing the pain will return. This supplement has truly saved my mental well-being. I am grateful to have discovered these alternatives which have transformed my health.
Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.6
8
Nattokinase aids cold recovery
We conducted a study to explore how a single dose of nattokinase (NK) influences recovery of skin temperature after exposure to cold water. This double-blind, placebo-controlled crossover study involved nine healthy men who took either NK or a placebo before submerging their hands in ice-cold water at 10 °C for one minute.
Our findings showed that participants who took NK experienced a quicker recovery of skin temperature in their middle finger, palm, and back of the hand compared to those who took the placebo. Although cold exposure initially caused a significant drop in skin temperature, the NK appeared to accelerate the warming process afterward.
Interestingly, we did not observe any changes in heart rate, cardiac output, or sympathetic nervous activity as a result of taking NK. This is noteworthy because it suggests that while NK may help with temperature recovery, it does not impact certain cardiovascular responses typically associated with cold exposure.
Overall, our study highlights the potential benefits of nattokinase, especially for individuals who are more sensitive to cold, such as women and the elderly. It could offer a new avenue for managing cold sensitivity and minimizing excessive vasoconstriction during chilly conditions.
Our findings showed that participants who took NK experienced a quicker recovery of skin temperature in their middle finger, palm, and back of the hand compared to those who took the placebo. Although cold exposure initially caused a significant drop in skin temperature, the NK appeared to accelerate the warming process afterward.
Interestingly, we did not observe any changes in heart rate, cardiac output, or sympathetic nervous activity as a result of taking NK. This is noteworthy because it suggests that while NK may help with temperature recovery, it does not impact certain cardiovascular responses typically associated with cold exposure.
Overall, our study highlights the potential benefits of nattokinase, especially for individuals who are more sensitive to cold, such as women and the elderly. It could offer a new avenue for managing cold sensitivity and minimizing excessive vasoconstriction during chilly conditions.
9
Significant improvement
Most Useful Review
285 people found this helpful
It is a great product for some people. I felt compelled to write a review about "Doctor's Best Best Nattokinase (2,000 Fu)" due to the improvement my family has experienced over the last two years. My father had a heart attack two and a half years ago, leading me to seek additional supplements. After research, I discovered Nattokinase and decided to try "Doctor's Best". The benefits are steady and substantial. After consulting the doctor, my father began taking 2k Fu pills daily, adjusting according to the seasons. A year later, his ECG reflected noticeable improvement, and recently, after two years, his condition has significantly improved, according to the doctor. I started it as well for high blood pressure, and I can see my levels have dropped.
Heart Attack details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.8
USERS' SCORE
Good
Based on 5 Reviews
8.6
9.5
We aimed to explore the effectiveness of nattokinase, an enzyme with potent fibrinolytic properties, in treating heart attacks. Through our research, we focused on enhancing the production of nattokinase from a newly identified strain of Pseudomonas aeruginosa, referred to as CMSS, which we isolated from cow milk.
Our comprehensive study involved optimizing different growth conditions such as pH, temperature, and nutrient sources, alongside improving the strain through UV-mutagenesis. We were excited to find that these optimizations led to a significant increase in nattokinase production.
The standout results showed that our modified strain produced nattokinase with a maximum activity of 4263 U mL(-1), which is double that of the original strain. In practical terms, this nattokinase achieved an impressive 94% blood clot lysis within ten minutes, hinting at its potential as a rapid acting treatment for heart-related issues.
Overall, our findings suggest that nattokinase from Pseudomonas aeruginosa CMSS could be a promising candidate for thrombolytic therapy, notably for those at risk of acute myocardial infarction. This unique study represents the first report of nattokinase production from this microorganism, opening the door to further research.
Our comprehensive study involved optimizing different growth conditions such as pH, temperature, and nutrient sources, alongside improving the strain through UV-mutagenesis. We were excited to find that these optimizations led to a significant increase in nattokinase production.
The standout results showed that our modified strain produced nattokinase with a maximum activity of 4263 U mL(-1), which is double that of the original strain. In practical terms, this nattokinase achieved an impressive 94% blood clot lysis within ten minutes, hinting at its potential as a rapid acting treatment for heart-related issues.
Overall, our findings suggest that nattokinase from Pseudomonas aeruginosa CMSS could be a promising candidate for thrombolytic therapy, notably for those at risk of acute myocardial infarction. This unique study represents the first report of nattokinase production from this microorganism, opening the door to further research.
9
Significant heart issue relief
Most Useful Review
76 people found this helpful
It works wonderfully for my clogged veins and arteries! I combine this with serrapeptase, unsure which is more effective but committed to both. Suffering from severe type 2 diabetes, I previously faced heart spasms that were quite alarming, making me fear a heart attack was imminent. After taking Nattokinase, my heart problems vanished within two days! Unlikely coincidence, this supplement has offered the most noticeable results of any I've tried.
Atrial Fibrillation details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Improved heart rate
Most Useful Review
50 people found this helpful
I'm taking supplements for my knee pain that have surprisingly regularised my heart rate. I’ve atrial fibrillation, and to prevent blood clots, my cardiologist prescribes Prodaxa. With these supplements, my heart has never felt better, and I'm free of side effects.
Headache details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
Lower medication needs
Most Useful Review
34 people found this helpful
After changing several high blood pressure medications, I experienced side effects like headaches and stomach irritation. A friend recommended Natokinase. I began taking one capsule daily, which has been amazing! I’ve reduced my medication dosage, and my blood pressure is now well-controlled without any side effects. Highly recommend!
Blood Clot details
SCIENTIFIC SCORE
Moderately Effective
Based on 18 Researches
8.4
USERS' SCORE
Good
Based on 22 Reviews
8.4
9
Nattokinase shows strong clot-busting activity
We explored the effectiveness of nattokinase, a natural enzyme known for its role in breaking down blood clots, by studying its production and activity in a lab setting. Nattokinase was extracted from Bacillus subtilis, and we introduced this gene into E. coli bacteria to produce the enzyme at high levels.
Through our process, we purified the active recombinant nattokinase and tested its ability to dissolve blood clots. Our results were promising; the enzyme exhibited a fibrinolytic activity of 58FU/mg, which is notably five times more effective than the currently used drug, orokinase.
We optimized the conditions for producing nattokinase, including factors like temperature and nutrient concentrations, resulting in an impressive yield of 1805.50 mg/L. This improved production method paves the way for scaling up nattokinase's use in treating cardiovascular diseases related to blood clots. The findings emphasize nattokinase's potential as an effective thrombolytic agent.
Through our process, we purified the active recombinant nattokinase and tested its ability to dissolve blood clots. Our results were promising; the enzyme exhibited a fibrinolytic activity of 58FU/mg, which is notably five times more effective than the currently used drug, orokinase.
We optimized the conditions for producing nattokinase, including factors like temperature and nutrient concentrations, resulting in an impressive yield of 1805.50 mg/L. This improved production method paves the way for scaling up nattokinase's use in treating cardiovascular diseases related to blood clots. The findings emphasize nattokinase's potential as an effective thrombolytic agent.
10
Life-saving product
Most Useful Review
316 people found this helpful
This could save your life! I love this nattokinase and believe everyone should be taking it. It could literally save your life! The nattozymes dissolve a blood clot on contact. Many years ago, a Japanese scientist discovered this by accident. After years of trying everything, I tried this product, and the next day was the best day I've had in ages—full of energy, no pain, and my blood pressure was perfect.
Stroke details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.5
USERS' SCORE
Good
Based on 5 Reviews
8
8
We explored how nattokinase, a serine protease derived from the traditional food natto, can benefit individuals who have experienced strokes, particularly focusing on cognitive recovery. Our study specifically aimed to uncover whether nattokinase can act as an anti-post-stroke cognitive impairment (PSCI) agent by influencing blood factors that are crucial for brain health.
The results were telling. We discovered that nattokinase has protective effects against acute ischemic strokes and plays a significant role in promoting neurogenesis, which is the process of generating new brain cells. Through experiments conducted on rat models, we observed that nattokinase notably increases irisin levels in peripheral blood. Irisin is a protein that has emerged as an interesting player in enhancing cognitive functions.
By linking the increased levels of irisin to improved cognitive abilities, our findings suggest that nattokinase could be a promising therapy for those suffering from PSCI, positioning irisin as a potential target for treatment. Overall, our research highlights the exciting possibilities that nattokinase offers in the realm of stroke recovery and brain health.
The results were telling. We discovered that nattokinase has protective effects against acute ischemic strokes and plays a significant role in promoting neurogenesis, which is the process of generating new brain cells. Through experiments conducted on rat models, we observed that nattokinase notably increases irisin levels in peripheral blood. Irisin is a protein that has emerged as an interesting player in enhancing cognitive functions.
By linking the increased levels of irisin to improved cognitive abilities, our findings suggest that nattokinase could be a promising therapy for those suffering from PSCI, positioning irisin as a potential target for treatment. Overall, our research highlights the exciting possibilities that nattokinase offers in the realm of stroke recovery and brain health.
7.5
No side effects reported
Most Useful Review
22 people found this helpful
After having a carotid artery stroke in March 2012, I weaned off my blood thinner. Instead of low dose aspirin, I tried Dr Best Nattokinase. I experienced no side effects, no follow-on strokes or TIAs. While I did notice that cuts took longer to coagulate, excessive anti-coagulation can lead to issues as well. Those on Coumadin should consult their doctor before using this product.
