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The results were telling. We discovered that nattokinase has protective effects against acute ischemic strokes and plays a significant role in promoting neurogenesis, which is the process of generating new brain cells. Through experiments conducted on rat models, we observed that nattokinase notably increases irisin levels in peripheral blood. Irisin is a protein that has emerged as an interesting player in enhancing cognitive functions.
By linking the increased levels of irisin to improved cognitive abilities, our findings suggest that nattokinase could be a promising therapy for those suffering from PSCI, positioning irisin as a potential target for treatment. Overall, our research highlights the exciting possibilities that nattokinase offers in the realm of stroke recovery and brain health.
Our observations revealed that NK treatment significantly reduced the size of brain injury and enhanced recovery from neurological issues. It also helped lower levels of harmful pro-inflammatory and coagulation substances while reducing oxidative stress markers in the affected brain area. These findings show NK’s potential in protecting the brain from the damaging effects of stroke.
Furthermore, we explored NK's protective properties in laboratory tests simulating neuron injury due to lack of oxygen and glucose. We found that it was effective in countering cell death across these models, working through various biological pathways. However, when we blocked NK's activity with a specific inhibitor, we noticed that its protective effects vanished, demonstrating that NK's enzymatic activity is crucial for its benefits.
Overall, this study highlights the multi-faceted protective role of nattokinase in brain injuries caused by ischemic events, confirming its potential as a therapeutic agent in stroke treatment.
After 60 days, both the Nattospes and control groups showed significant improvements in physical activities, blood pressure, and quality of life. While Nattospes demonstrated beneficial effects on stroke symptoms, it’s important to note that no adverse effects were reported.
The results suggest that Nattospes can safely support stroke recovery. These findings encourage further research into Nattospes as a potential supplement in cardiovascular disease management.
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Our observations revealed that NK treatment significantly reduced the size of brain injury and enhanced recovery from neurological issues. It also helped lower levels of harmful pro-inflammatory and coagulation substances while reducing oxidative stress markers in the affected brain area. These findings show NK’s potential in protecting the brain from the damaging effects of stroke.
Furthermore, we explored NK's protective properties in laboratory tests simulating neuron injury due to lack of oxygen and glucose. We found that it was effective in countering cell death across these models, working through various biological pathways. However, when we blocked NK's activity with a specific inhibitor, we noticed that its protective effects vanished, demonstrating that NK's enzymatic activity is crucial for its benefits.
Overall, this study highlights the multi-faceted protective role of nattokinase in brain injuries caused by ischemic events, confirming its potential as a therapeutic agent in stroke treatment.
While both treatments lowered cholesterol and triglyceride levels, statins achieved greater reductions. Interestingly, nattokinase raised good cholesterol levels, unlike statins. Our study suggests that nattokinase could be a promising alternative in managing atherosclerosis and reducing stroke risk.
The results were telling. We discovered that nattokinase has protective effects against acute ischemic strokes and plays a significant role in promoting neurogenesis, which is the process of generating new brain cells. Through experiments conducted on rat models, we observed that nattokinase notably increases irisin levels in peripheral blood. Irisin is a protein that has emerged as an interesting player in enhancing cognitive functions.
By linking the increased levels of irisin to improved cognitive abilities, our findings suggest that nattokinase could be a promising therapy for those suffering from PSCI, positioning irisin as a potential target for treatment. Overall, our research highlights the exciting possibilities that nattokinase offers in the realm of stroke recovery and brain health.
After 60 days, both the Nattospes and control groups showed significant improvements in physical activities, blood pressure, and quality of life. While Nattospes demonstrated beneficial effects on stroke symptoms, it’s important to note that no adverse effects were reported.
The results suggest that Nattospes can safely support stroke recovery. These findings encourage further research into Nattospes as a potential supplement in cardiovascular disease management.
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Frequently Asked Questions
A stroke occurs when the blood supply to a part of the brain is interrupted or reduced, preventing brain tissue from getting oxygen and nutrients. This can happen in two primary ways: an ischemic stroke, which occurs when a blood vessel supplying blood to the brain is obstructed, often due to a blood clot; and a hemorrhagic stroke, which occurs when a blood vessel in the brain bursts, leading to bleeding in or around the brain. The severity and outcome of a stroke can vary widely depending on the type, location, and amount of brain tissue affected, as well as the speed with which medical treatment is received.
Recognizing the symptoms of a stroke is crucial for prompt treatment and recovery. Common signs include sudden numbness or weakness in the face, arm, or leg, especially on one side of the body, confusion, trouble speaking or understanding speech, vision problems in one or both eyes, and difficulty walking, which may include dizziness or loss of balance coordination. The acronym FAST can help remember the key signs: Face drooping, Arm weakness, Speech difficulty, and Time to call emergency services. If you or someone you know exhibits these symptoms, it's vital to seek immediate medical attention, as timely intervention can significantly improve outcomes.
Nattokinase is an enzyme extracted from a traditional Japanese food called natto, which is made from fermented soybeans. This enzyme is thought to have potential health benefits, primarily for cardiovascular health. Nattokinase is believed to support the breakdown of fibrin in the blood, which can help improve circulation and reduce the risk of blood clot formation. As a dietary supplement, it is often marketed for its possible ability to promote healthy blood flow and cardiovascular function.
While some studies suggest that nattokinase may help reduce blood pressure and enhance overall heart health, research is still ongoing. As with any supplement, it is essential to consult with a healthcare professional before adding nattokinase to your regimen, especially if you are on blood-thinning medications or have underlying health conditions. Overall, while nattokinase might offer some intriguing health benefits, more comprehensive studies are needed to fully understand its efficacy and safety profile.
Based on user reviews, the timeframe for seeing results from taking nattokinase as a supplement for stroke prevention can vary. Many users report positive effects after a few days, with some experiencing improvements in their condition and symptoms in as little as that time frame. For instance, one reviewer mentioned a significant improvement in discomfort within a few days of starting the supplement (Read Review). Others, however, suggest that it may take a longer duration of consistent use, with some users taking the supplement for several months or even years without any adverse effects and experiencing sustained benefits (Read Review).
Interestingly, many long-term users, some reporting over ten years of use, indicate that nattokinase has played a significant role in stabilizing their health and preventing further incidents related to strokes (Read Review). This suggests that while initial benefits may appear relatively quickly, the most substantial and lasting effects could be observed over longer treatment periods. Therefore, users considering nattokinase for stroke should remain consistent and patient, as the results can develop over time.
Nattokinase has emerged as a noteworthy supplement in the realm of stroke recovery, demonstrating strong scientific backing for its potential benefits. Research has shown that nattokinase can significantly reduce brain injury and aid recovery following ischemic strokes in animal models. A study involving transient middle cerebral artery occlusion indicated that the enzyme not only diminished brain damage but also lowered harmful pro-inflammatory substances and oxidative stress markers, showcasing its protective properties in stroke incidents [1]. Furthermore, its role in promoting neurogenesis and cognitive recovery post-stroke has been highlighted through experiments indicating increased levels of irisin, a protein associated with enhanced cognitive function [2].
Additional studies, including a randomized controlled trial, reinforce these findings by demonstrating that Nattospes, a supplement containing nattokinase, supports physical activity, quality of life, and overall stroke recovery without adverse effects [3]. These compelling results suggest that nattokinase may serve as a promising therapeutic agent in the cardiovascular and neurological health landscape. Given its ability to improve both physical and cognitive outcomes after strokes, further research into its application and effectiveness could significantly benefit stroke rehabilitation strategies.
Users have reported a range of improvements in their symptoms after incorporating nattokinase into their health routines, particularly in relation to blood viscosity and stroke prevention. Many individuals share experiences of having switched from traditional medications like aspirin or Warfarin to nattokinase, citing advantages such as improved blood fluidity and the absence of side effects. For example, one user noted that after replacing Warfarin with nattokinase, they no longer experienced blood spots under their skin and felt overall stability in their health (Read Review). Similarly, those who have suffered strokes reported no further clotting issues after consistently using the supplement (Read Review).
Additionally, several reviewers mentioned an enhancement in cognitive functions and general health improvements, especially following previous stroke incidents. For instance, a user reported that their mother experienced cognitive improvement after taking three daily capsules, which likely helped prevent another stroke (Read Review). While individual results can vary, these anecdotal experiences indicate that nattokinase may serve as a beneficial alternative for maintaining cardiovascular health and preventing serious complications associated with stroke.
Users have reported significant benefits from combining nattokinase with other supplements or medications to handle stroke risk and symptoms. Notably, some users have switched from traditional blood thinners like aspirin and Warfarin to nattokinase, citing fewer side effects and improved outcomes. For example, one user stated that after transitioning from Warfarin to nattokinase, they noticed no further blood spots and felt overall stability in their health (Read Review). Others highlighted that nattokinase helped them maintain normal blood viscosity and circulation while eliminating concerns of clotting issues after strokes (Read Review).
Additionally, several individuals reported positive interactions with other supplements, particularly omega-3 fatty acids. One user noted that their father experienced improved health post-stroke after replacing aspirin with nattokinase and taking it alongside omega-3 (Read Review). This suggests a collaborative effect on cardiovascular health, emphasizing the holistic approach users are taking by combining nattokinase with other supportive dietary choices. Overall, the evidence from user experiences points to nattokinase not only as a standalone option for stroke prevention but also as a synergistic partner with other health supplements.
Based on user reviews, the appropriate dose of Nattokinase for treating stroke prevention generally appears to range from two to four capsules daily. Many users report taking two capsules in the morning and two in the evening to maintain continued effectiveness and optimal blood thinning properties (Read Review), (Read Review). Some users have described their experience as beneficial, noting that after switching to Nattokinase from conventional blood thinners like aspirin, they experienced no adverse effects and reported a sense of stability in their health conditions (Read Review), (Read Review).
Users suggest taking Nattokinase on an empty stomach, particularly in the morning, and some also recommend evening doses for the best results (Read Review), (Read Review). Overall, there is a consensus among users that, when used properly as a replacement for conventional blood thinners, Nattokinase contributes to better cardiovascular health and helps reduce the risk of stroke recurrence.
Our observations revealed that NK treatment significantly reduced the size of brain injury and enhanced recovery from neurological issues. It also helped lower levels of harmful pro-inflammatory and coagulation substances while reducing oxidative stress markers in the affected brain area. These findings show NK’s potential in protecting the brain from the damaging effects of stroke.
Furthermore, we explored NK's protective properties in laboratory tests simulating neuron injury due to lack of oxygen and glucose. We found that it was effective in countering cell death across these models, working through various biological pathways. However, when we blocked NK's activity with a specific inhibitor, we noticed that its protective effects vanished, demonstrating that NK's enzymatic activity is crucial for its benefits.
Overall, this study highlights the multi-faceted protective role of nattokinase in brain injuries caused by ischemic events, confirming its potential as a therapeutic agent in stroke treatment.
The results were telling. We discovered that nattokinase has protective effects against acute ischemic strokes and plays a significant role in promoting neurogenesis, which is the process of generating new brain cells. Through experiments conducted on rat models, we observed that nattokinase notably increases irisin levels in peripheral blood. Irisin is a protein that has emerged as an interesting player in enhancing cognitive functions.
By linking the increased levels of irisin to improved cognitive abilities, our findings suggest that nattokinase could be a promising therapy for those suffering from PSCI, positioning irisin as a potential target for treatment. Overall, our research highlights the exciting possibilities that nattokinase offers in the realm of stroke recovery and brain health.
After 60 days, both the Nattospes and control groups showed significant improvements in physical activities, blood pressure, and quality of life. While Nattospes demonstrated beneficial effects on stroke symptoms, it’s important to note that no adverse effects were reported.
The results suggest that Nattospes can safely support stroke recovery. These findings encourage further research into Nattospes as a potential supplement in cardiovascular disease management.
References
- Yang XY, Wang SL, Xue WC, Zhang YP, Li LL, et al. Nattokinase's Neuroprotective Mechanisms in Ischemic Stroke: Targeting Inflammation, Oxidative Stress, and Coagulation. Antioxid Redox Signal. 2025;42:228. doi:10.1089/ars.2023.0527
- Wu H, Zhang Q, Xu P, Chen J, Duan L, et al. Nattokinase Promotes Post-stroke Neurogenesis and Cognition Recovery via Increasing Circulating Irisin. J Agric Food Chem. 2023;71:11418. doi:10.1021/acs.jafc.2c08718
- Pham PT, Han B, Hoang BX. Nattospes as Effective and Safe Functional Supplements in Management of Stroke. J Med Food. 2020;23:879. doi:10.1089/jmf.2019.0183
- Ren NN, Chen HJ, Li Y, Mcgowan GW, Lin YG. [A clinical study on the effect of nattokinase on carotid artery atherosclerosis and hyperlipidaemia]. Zhonghua Yi Xue Za Zhi. 2017;97:2038. doi:10.3760/cma.j.issn.0376-2491.2017.26.005
