Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.8
Supplement Facts
Serving Size: 3 Capsules
Serving Per Container: 120
Amount Per Serving
%DV
MSM (Methylsulfonylmethane) (OptiMSM®)
3,000 mg
†
Top Medical Research Studies
8
We investigated how methylsulfonylmethane (MSM) interacts with bone morphogenetic protein 2 (BMP-2) to potentially enhance the differentiation of mesenchymal stem cells (MSCs) into osteoblasts, which are crucial for bone health. The study revealed that both MSM and BMP-2, when combined, lead to increased levels of certain proteins that aid in this process.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Read More
Most Useful Reviews
9
Joint health support
Great product for joint health and osteoporosis support.
Read More
9
Coped well
I take sulfur complete with glucosamine, and it excellently manages my osteoporosis.
Read More
7.5
Increased flexibility
I use it in my battle against osteoporosis. It makes me feel more flexible and mobile and acts as a good antioxidant. It supports connective tissue and has anti-inflammatory properties. I take it and then rest.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We investigated how methylsulfonylmethane (MSM) interacts with bone morphogenetic protein 2 (BMP-2) to potentially enhance the differentiation of mesenchymal stem cells (MSCs) into osteoblasts, which are crucial for bone health. The study revealed that both MSM and BMP-2, when combined, lead to increased levels of certain proteins that aid in this process.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Joint health support
Great product for joint health and osteoporosis support.
Read More
9
Coped well
I take sulfur complete with glucosamine, and it excellently manages my osteoporosis.
Read More
7.5
Increased flexibility
I use it in my battle against osteoporosis. It makes me feel more flexible and mobile and acts as a good antioxidant. It supports connective tissue and has anti-inflammatory properties. I take it and then rest.
Read More
7.5
Body preference noted
My body liked this product but preferred the same brand with glucosamine and the Opti MSM. As I suffer from significant osteoporosis, I'm pleased to have found something my body responds positively to. The product arrived quickly, was well packaged, and had free postage.
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6
Pain reduction noted
Doctor's Best MSM with optimsm assists in protecting bones and alleviating pain associated with osteoporosis and osteoarthritis.
Read More
Frequently Asked Questions
6
Cumulative benefits
If you have issues with joints, cartilage, or muscles, I was advised to take sulfur as I have osteoporosis. Methylsulfonylmethane helps restore musculoskeletal structures and has a cumulative effect, so it should be taken long-term. The capsules are small, easy to swallow, and tasteless. I highly recommend it.
7.5
Body preference noted
My body liked this product but preferred the same brand with glucosamine and the Opti MSM. As I suffer from significant osteoporosis, I'm pleased to have found something my body responds positively to. The product arrived quickly, was well packaged, and had free postage.
2
Limited relief
I bought this for my mother, who suffers from osteoporosis, but she was not happy with the results from this brand. She felt it didn’t provide much relief compared to other brands.
7.5
Increased flexibility
I use it in my battle against osteoporosis. It makes me feel more flexible and mobile and acts as a good antioxidant. It supports connective tissue and has anti-inflammatory properties. I take it and then rest.
6
Pain reduction noted
Doctor's Best MSM with optimsm assists in protecting bones and alleviating pain associated with osteoporosis and osteoarthritis.
9
Coped well
I take sulfur complete with glucosamine, and it excellently manages my osteoporosis.
9
Joint health support
Great product for joint health and osteoporosis support.
8
We investigated how methylsulfonylmethane (MSM) interacts with bone morphogenetic protein 2 (BMP-2) to potentially enhance the differentiation of mesenchymal stem cells (MSCs) into osteoblasts, which are crucial for bone health. The study revealed that both MSM and BMP-2, when combined, lead to increased levels of certain proteins that aid in this process.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
References
- Kim DN, Joung YH, Darvin P, Kang DY, Sp N, et al. Methylsulfonylmethane enhances BMP‑2‑induced osteoblast differentiation in mesenchymal stem cells. Mol Med Rep. 2016;14:460. doi:10.3892/mmr.2016.5274
