Research Authors

Overview

SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.9
USERS' SCORE
Good
Based on 9 Reviews
8.5
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Selenium (from SelenoExcell® High Selenium Yeast) (Saccharomyces cerevisiae)
50 mcg
90%
Molybdenum (from molybdenum glycinate chelate)
50 mcg
110%
N-Acetylcysteine (NAC)
600 mg

Top Medical Research Studies

We analyzed data from two clinical trials involving 579 individuals with Irritable Bowel Syndrome (IBS) to determine how CNCM I-3856 affects symptoms like bloating.

Our findings revealed that during the second month of supplementation, participants experienced significant reductions in both abdominal pain and bloating—up to 14.9% compared to those taking a placebo.

While intestinal symptoms improved, there were no significant differences observed between groups at the end of treatment. However, stool consistency was notably better in those taking CNCM I-3856.
Read More
7
Sourdough improves stomach comfort
We examined how sourdough baked goods affect bloating and other gastrointestinal symptoms in healthy adults. Using a double-blind, randomized crossover method, we served participants either sourdough or brewer's yeast croissants and monitored gastric emptying and hydrogen production.

The results suggested that sourdough may promote better gastrointestinal function and be more tolerable compared to brewer's yeast products. This indicates that switching to sourdough could alleviate some post-meal discomfort, including bloating.
Read More
7
Yeast treatment shows mixed results
We investigated the effects of EpiCor fermentate on gastrointestinal discomfort and constipation, focusing on bloating. In a randomized double-blind trial, eighty participants tracked their symptoms over six weeks, comparing a yeast-based treatment to a placebo. While the results showed that EpiCor could positively influence gut microbiome composition and improve constipation symptoms, there was no significant direct benefit reported for bloating relief. So, while EpiCor can help with certain bowel issues, its effectiveness may not extend to all gastrointestinal discomforts.
Read More

Most Useful Reviews

10
Bloating resolved
30 people found this helpful
This drug really surprised me. It worked well for me. The bloating has gone, and I have lost a few kilos. I have gallbladder problems, but when I take this drug, I feel great. The bile doesn't stagnate anymore. The capsules are small and easy to swallow. Definitely a repeat purchase! I recommend it to everyone!
Read More
10
Bloating gone
1 people found this helpful
I was very surprised by this drug. It worked perfectly for me. Bloating has passed, and I've lost several kilograms. I have gallbladder issues, but when I take this drug, I feel fine. The bile no longer stagnates. The capsules are small and easy to swallow. Definitely a repeat purchase! I highly recommend it!
Read More
10
Bloating relief
This drug really surprised me. It worked just fine for me. The bloating went away, and I lost a few kilos. I have gallbladder issues, but when I drink this drug, I feel great. The bile doesn't stagnate anymore. The capsules are small and easy to swallow. A definite repeat purchase! I recommend it to everyone!
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.9
  • All Researches
We analyzed data from two clinical trials involving 579 individuals with Irritable Bowel Syndrome (IBS) to determine how CNCM I-3856 affects symptoms like bloating.

Our findings revealed that during the second month of supplementation, participants experienced significant reductions in both abdominal pain and bloating—up to 14.9% compared to those taking a placebo.

While intestinal symptoms improved, there were no significant differences observed between groups at the end of treatment. However, stool consistency was notably better in those taking CNCM I-3856.
Read More
We analyzed the effectiveness of sacrosidase from Saccharomyces cerevisiae in reducing gastrointestinal symptoms, including bloating, in children with congenital sucrase-isomaltase deficiency (CSID).

In a randomized, double-blind trial involving 28 children, results indicated that sacrosidase effectively minimized diarrhea, abdominal cramps, gas, and bloating, particularly when consumed alongside a regular diet.

By measuring symptoms and daily stool counts over several phases, we found sacrosidase to be a safe and effective option for managing CSID symptoms.
Read More
7
Sourdough improves stomach comfort
We examined how sourdough baked goods affect bloating and other gastrointestinal symptoms in healthy adults. Using a double-blind, randomized crossover method, we served participants either sourdough or brewer's yeast croissants and monitored gastric emptying and hydrogen production.

The results suggested that sourdough may promote better gastrointestinal function and be more tolerable compared to brewer's yeast products. This indicates that switching to sourdough could alleviate some post-meal discomfort, including bloating.
Read More
7
Yeast treatment shows mixed results
We investigated the effects of EpiCor fermentate on gastrointestinal discomfort and constipation, focusing on bloating. In a randomized double-blind trial, eighty participants tracked their symptoms over six weeks, comparing a yeast-based treatment to a placebo. While the results showed that EpiCor could positively influence gut microbiome composition and improve constipation symptoms, there was no significant direct benefit reported for bloating relief. So, while EpiCor can help with certain bowel issues, its effectiveness may not extend to all gastrointestinal discomforts.
Read More
7
Saccharomyces cerevisiae shows potential
We conducted a randomized, double-blind, placebo-controlled trial with 379 individuals diagnosed with irritable bowel syndrome (IBS) to investigate the effects of Saccharomyces cerevisiae (S. cerevisiae) on bloating and other symptoms.

Although the overall results showed no significant improvement in intestinal pain or discomfort for all IBS patients, we observed promising results in those with constipation. This subgroup experienced notable relief from bloating and abdominal pain, highlighting the need for further research in this area.
Read More

User Reviews

USERS' SCORE
Good
Based on 9 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Bloating resolved
30 people found this helpful
This drug really surprised me. It worked well for me. The bloating has gone, and I have lost a few kilos. I have gallbladder problems, but when I take this drug, I feel great. The bile doesn't stagnate anymore. The capsules are small and easy to swallow. Definitely a repeat purchase! I recommend it to everyone!
Read More
10
Bloating gone
1 people found this helpful
I was very surprised by this drug. It worked perfectly for me. Bloating has passed, and I've lost several kilograms. I have gallbladder issues, but when I take this drug, I feel fine. The bile no longer stagnates. The capsules are small and easy to swallow. Definitely a repeat purchase! I highly recommend it!
Read More
10
Bloating relief
This drug really surprised me. It worked just fine for me. The bloating went away, and I lost a few kilos. I have gallbladder issues, but when I drink this drug, I feel great. The bile doesn't stagnate anymore. The capsules are small and easy to swallow. A definite repeat purchase! I recommend it to everyone!
Read More
10
Bloating relief
The drug worked well for me; the swelling and bloating disappeared. I took it alongside homeopathy.
Read More
9
Bloating resolved
The drug worked well for me; the bloating has passed, and I’ve lost a few kilos. I have gallbladder problems, but when I take this drug, I feel great, and the bile no longer stagnates. The capsules are small and easy to swallow. I’m a repeat customer and highly recommend it!
Read More

Frequently Asked Questions

9
Bloating resolved
The drug worked well for me; the bloating has passed, and I’ve lost a few kilos. I have gallbladder problems, but when I take this drug, I feel great, and the bile no longer stagnates. The capsules are small and easy to swallow. I’m a repeat customer and highly recommend it!
0
Severe bloating
This product was not for me. I tried it for a month. Bloating started within 3-4 days, and despite continuing to take it, I felt severe bloating with no improvement. The smell was appalling, leading me to discard over 100 capsules. I cannot recommend this product.
10
Bloating resolved
30 people found this helpful
This drug really surprised me. It worked well for me. The bloating has gone, and I have lost a few kilos. I have gallbladder problems, but when I take this drug, I feel great. The bile doesn't stagnate anymore. The capsules are small and easy to swallow. Definitely a repeat purchase! I recommend it to everyone!
9
Reduced swelling
Great! I used it in a liver detoxification regimen. The product worked remarkably well; both swelling and bloating disappeared, and it had a positive effect on my skin. I took it alongside homeopathy.
2
No effect
I tried this product thoroughly, finishing the whole jar, but there was no effect. Enterosgel worked best for me (in gel form), as it made me feel better immediately, resolving my bloating and stomach pain.
10
Bloating gone
1 people found this helpful
I was very surprised by this drug. It worked perfectly for me. Bloating has passed, and I've lost several kilograms. I have gallbladder issues, but when I take this drug, I feel fine. The bile no longer stagnates. The capsules are small and easy to swallow. Definitely a repeat purchase! I highly recommend it!
7.5
Improved well-being
Keep eating, and you will feel better! Due to my job requiring overtime, taking NAC with protein enzymes has become my daily morning ritual. It aids my overall well-being and significantly improves my long-standing bloating issue!
7
Sourdough improves stomach comfort
We examined how sourdough baked goods affect bloating and other gastrointestinal symptoms in healthy adults. Using a double-blind, randomized crossover method, we served participants either sourdough or brewer's yeast croissants and monitored gastric emptying and hydrogen production.

The results suggested that sourdough may promote better gastrointestinal function and be more tolerable compared to brewer's yeast products. This indicates that switching to sourdough could alleviate some post-meal discomfort, including bloating.
7
Saccharomyces cerevisiae shows potential
We conducted a randomized, double-blind, placebo-controlled trial with 379 individuals diagnosed with irritable bowel syndrome (IBS) to investigate the effects of Saccharomyces cerevisiae (S. cerevisiae) on bloating and other symptoms.

Although the overall results showed no significant improvement in intestinal pain or discomfort for all IBS patients, we observed promising results in those with constipation. This subgroup experienced notable relief from bloating and abdominal pain, highlighting the need for further research in this area.
7
Yeast treatment shows mixed results
We investigated the effects of EpiCor fermentate on gastrointestinal discomfort and constipation, focusing on bloating. In a randomized double-blind trial, eighty participants tracked their symptoms over six weeks, comparing a yeast-based treatment to a placebo. While the results showed that EpiCor could positively influence gut microbiome composition and improve constipation symptoms, there was no significant direct benefit reported for bloating relief. So, while EpiCor can help with certain bowel issues, its effectiveness may not extend to all gastrointestinal discomforts.
We examined the effects of Saccharomyces cerevisiae on bloating in adults with irritable bowel syndrome. In a randomized double-blind study, 179 participants took either 500 mg of the yeast or a placebo for eight weeks.

While Saccharomyces cerevisiae significantly reduced abdominal pain, it showed only a slight non-significant trend in helping with bloating. Overall, participants tolerated the treatment well.

Therefore, while promising for abdominal pain, its impact on bloating remains unclear.

References

  1. Polese B, Nicolai E, Genovese D, Verlezza V, La Sala CN, et al. Postprandial Gastrointestinal Function Differs after Acute Administration of Sourdough Compared with Brewer's Yeast Bakery Products in Healthy Adults. J Nutr. 2018;148:202. 10.1093/jn/nxx049
  2. Pinheiro I, Robinson L, Verhelst A, Marzorati M, Winkens B, et al. A yeast fermentate improves gastrointestinal discomfort and constipation by modulation of the gut microbiome: results from a randomized double-blind placebo-controlled pilot trial. BMC Complement Altern Med. 2017;17:441. 10.1186/s12906-017-1948-0
  3. Cayzeele-Decherf A, Pélerin F, Leuillet S, Douillard B, Housez B, et al. CNCM I-3856 in irritable bowel syndrome: An individual subject meta-analysis. World J Gastroenterol. 2017;23:336. 10.3748/wjg.v23.i2.336
  4. Spiller R, Pélerin F, Cayzeele Decherf A, Maudet C, Housez B, et al. Randomized double blind placebo-controlled trial of Saccharomyces cerevisiae CNCM I-3856 in irritable bowel syndrome: improvement in abdominal pain and bloating in those with predominant constipation. United European Gastroenterol J. 2016;4:353. 10.1177/2050640615602571
  5. Pineton de Chambrun G, Neut C, Chau A, Cazaubiel M, Pelerin F, et al. A randomized clinical trial of Saccharomyces cerevisiae versus placebo in the irritable bowel syndrome. Dig Liver Dis. 2015;47:119. 10.1016/j.dld.2014.11.007
  6. Moya D, Calsamiglia S, Ferret A, Blanch M, Fandiño JI, et al. Effects of dietary changes and yeast culture (Saccharomyces cerevisiae) on rumen microbial fermentation of Holstein heifers. J Anim Sci. 2009;87:2874. 10.2527/jas.2008-1446
  7. Treem WR, McAdams L, Stanford L, Kastoff G, Justinich C, et al. Sacrosidase therapy for congenital sucrase-isomaltase deficiency. J Pediatr Gastroenterol Nutr. 1999;28:137.
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