'
Doctor's Best L-Theanine
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
USERS' SCORE
Good
Based on 8 Reviews
8.5
Supplement Facts
Serving Size: 1 Veggie Capsule
Serving Per Container:  90
Amount Per Serving
%DV
L-Theanine (Suntheanine®)
150 mg

Top Medical Research Studies

8
L-theanine shows potential antidepressant effects
L-theanine ameliorate depressive-like behavior in a chronic unpredictable mild stress rat model via modulating the monoamine levels in limbic-cortical-striatal-pallidal-thalamic-circuit related brain regions.
Study shows neurotransmitter modulation
We examined how L-theanine, a compound found in green tea, influences depressive behaviors in a rat model. Using specific behavioral tests, such as the open-field and forced swim tests, we observed that L-theanine improved depressive-like behaviors.

Our findings indicated that it boosted levels of key neurotransmitters—serotonin, norepinephrine, and dopamine—in certain brain regions. This suggests that L-theanine could have potential antidepressant effects, possibly by interacting with these neurotransmitters in brain areas associated with mood regulation.
Read More
8
Effects of l-theanine on depression
Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study.
Study suggests potential benefits
We explored the effects of l-theanine, a natural amino acid found in green tea, on patients diagnosed with major depressive disorder (MDD) in an 8-week open-label study. We involved 20 participants who took 250 mg of l-theanine daily in addition to their regular medication.

Our findings indicated a significant reduction in depression and anxiety symptoms, as well as improved sleep quality and cognitive functions. However, it's important to note that because this study wasn't placebo-controlled, further research is needed to confirm these promising effects.
Read More
8
l-theanine shows promise for depression
l-theanine adjunct to sertraline for major depressive disorder: A randomized, double-blind, placebo-controlled clinical trial.
Relevant study with positive findings
We investigated the effects of l-theanine added to sertraline in treating major depressive disorder (MDD). In a six-week, double-blind trial, participants took either l-theanine or a placebo alongside their medication. Results showed that those receiving l-theanine experienced a greater reduction in depression symptoms and higher remission rates compared to the placebo group. Though the study had a small sample size, the findings suggest l-theanine may be a promising adjunct therapy for improving treatment outcomes in MDD. More extensive research is needed for confirmation.
Read More

Most Useful Reviews

8.8
Stress reduced
Simply having this in my bag makes me feel better. I find it brings a sense of peace without the chemical dullness typical of other stress or depression medications. The 150mg dosage per capsule seems just right—providing a subtle calming effect and alleviating feelings of paranoia.
Read More
8.8
Calmness improved
I purchased this for my mother, who has long battled insomnia and depression. After just a week of taking L-theanine, she noticed a change; she feels calm, and her anxiety seems under control now. I'm pleased with iHerb's service too – living in Vietnam, the delivery was swift at only a week!
Read More
8.8
Mild depression helped
This is quite beneficial for mild depression. However, it's crucial to never take it alongside prescription antidepressants or as a replacement in severe cases of depression.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
  • All Researches
8
l-theanine shows promise for depression
l-theanine adjunct to sertraline for major depressive disorder: A randomized, double-blind, placebo-controlled clinical trial.
Relevant study with positive findings
We investigated the effects of l-theanine added to sertraline in treating major depressive disorder (MDD). In a six-week, double-blind trial, participants took either l-theanine or a placebo alongside their medication. Results showed that those receiving l-theanine experienced a greater reduction in depression symptoms and higher remission rates compared to the placebo group. Though the study had a small sample size, the findings suggest l-theanine may be a promising adjunct therapy for improving treatment outcomes in MDD. More extensive research is needed for confirmation.
Read More
8
L-theanine shows potential antidepressant effects
L-theanine ameliorate depressive-like behavior in a chronic unpredictable mild stress rat model via modulating the monoamine levels in limbic-cortical-striatal-pallidal-thalamic-circuit related brain regions.
Study shows neurotransmitter modulation
We examined how L-theanine, a compound found in green tea, influences depressive behaviors in a rat model. Using specific behavioral tests, such as the open-field and forced swim tests, we observed that L-theanine improved depressive-like behaviors.

Our findings indicated that it boosted levels of key neurotransmitters—serotonin, norepinephrine, and dopamine—in certain brain regions. This suggests that L-theanine could have potential antidepressant effects, possibly by interacting with these neurotransmitters in brain areas associated with mood regulation.
Read More
8
Effects of l-theanine on depression
Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study.
Study suggests potential benefits
We explored the effects of l-theanine, a natural amino acid found in green tea, on patients diagnosed with major depressive disorder (MDD) in an 8-week open-label study. We involved 20 participants who took 250 mg of l-theanine daily in addition to their regular medication.

Our findings indicated a significant reduction in depression and anxiety symptoms, as well as improved sleep quality and cognitive functions. However, it's important to note that because this study wasn't placebo-controlled, further research is needed to confirm these promising effects.
Read More
7
L-theanine shows promise for mental health
Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
Relevant study on L-theanine benefits
This study focused on how L-theanine, administered over four weeks, affects stress-related symptoms and cognitive functions in healthy adults.

We found that participants who took 200 mg of L-theanine daily reported decreased depression, anxiety, and improved sleep quality compared to those on a placebo. Measures like verbal fluency and executive function showed significant improvements as well.

Our results suggest that L-theanine could be a helpful option for those facing stress and cognitive challenges, promoting better mental well-being.
Read More

User Reviews

USERS' SCORE
Good
Based on 8 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8.8
Stress reduced
Simply having this in my bag makes me feel better. I find it brings a sense of peace without the chemical dullness typical of other stress or depression medications. The 150mg dosage per capsule seems just right—providing a subtle calming effect and alleviating feelings of paranoia.
8.8
Calmness improved
I purchased this for my mother, who has long battled insomnia and depression. After just a week of taking L-theanine, she noticed a change; she feels calm, and her anxiety seems under control now. I'm pleased with iHerb's service too – living in Vietnam, the delivery was swift at only a week!
Read More
8.8
Mild depression helped
This is quite beneficial for mild depression. However, it's crucial to never take it alongside prescription antidepressants or as a replacement in severe cases of depression.
8.3
Better concentration
My concentration appears to have improved, and I've noticed that my depression seems to be alleviated.
6.3
Increased energy
This is the best! I was struggling with depression and a lack of energy, but lately, I feel much better. Taking it with tyrosine appears to be more effective.
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