Last update
4/2/2026
Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Medium or Average
Based on 20 Reviews
6.7
Supplement Facts
Serving Size:   1 Veggie Capsule
Amount Per Serving
%DV
Vitamin C (as Q®-C ascorbic acid)
1000 mg
1111%
📅 Last updated:

Top Medical Research Studies

8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More

Most Useful Reviews

0
Causes bad heartburn
1 people found this helpful
I can actually taste the artificial flavour in this vitamin C, and it causes me severe heartburn, making me doubt its naturalness.
Read More
0
Induces heartburn
1 people found this helpful
I often feel heartburn or discomfort in my stomach after taking it.
Read More
9
No heartburn experienced
Everyone enjoyed their meals as if we were dining as a family. I take one pill daily after eating along with other nutritional supplements, and I did not experience any heartburn.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More

User Reviews

USERS' SCORE
Medium or Average
Based on 20 Reviews
6.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
0
Causes bad heartburn
1 people found this helpful
I can actually taste the artificial flavour in this vitamin C, and it causes me severe heartburn, making me doubt its naturalness.
Read More
0
Induces heartburn
1 people found this helpful
I often feel heartburn or discomfort in my stomach after taking it.
Read More
9
No heartburn experienced
Everyone enjoyed their meals as if we were dining as a family. I take one pill daily after eating along with other nutritional supplements, and I did not experience any heartburn.
Read More
9
Eases heartburn
If you, like me, don't consume fruit often, this is necessary. It's easy to take, and I haven't had any heartburn.
Read More
9
Family-friendly
I liked it. The capsules did not turn yellow, unlike others. My family, who typically can’t take vitamin C due to heartburn, enjoy this product and often buy it as a gift.
Read More

Frequently Asked Questions

9
No heartburn after years
I’ve been taking this product for about three years, starting with 1g after meals three times a day, now increased to 2g. I haven’t experienced any heartburn or stomach issues yet.
0
Induces heartburn
1 people found this helpful
I often feel heartburn or discomfort in my stomach after taking it.
7.5
Avoid on empty stomach
Buy a bottle of vitamin C! I take 2 to 3 tablets daily after meals. Taking it on an empty stomach may cause heartburn, so I recommend taking it post-meal.
0
Causes heartburn
I am dissatisfied as it has a stronger sour taste than before and induces heartburn. I can’t continue taking it because of the heartburn.
9
No heartburn experienced
Everyone enjoyed their meals as if we were dining as a family. I take one pill daily after eating along with other nutritional supplements, and I did not experience any heartburn.
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.

References

  1. Jin D, Wang J, Zhan Q, Huang K, Wang H, et al. The safety and efficacy of 2% vitamin C solution spray for relief of mucosal irritation caused by Lugol chromoendoscopy: a multicenter, randomized, double-blind, parallel trial. Gastrointest Endosc. 2020;92:554. 10.1016/j.gie.2019.11.028
Data last updated:
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