'
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size:   1 Veggie Capsule
Amount Per Serving
%DV
Vitamin C (as Q®-C ascorbic acid)
1000 mg
1111%

Top Medical Research Studies

8
Vitamin C aids omeprazole therapy
Antioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis.
Moderate relevance to reflux treatment
We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.

We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.

This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
Read More
7
Antioxidants may reduce cancer risk
Dietary antioxidant and mineral intake in humans is associated with reduced risk of esophageal adenocarcinoma but not reflux esophagitis or Barrett's esophagus.
Limited isolation of vitamin C effects
We studied how antioxidants, particularly vitamin C, relate to reflux esophagitis and esophageal adenocarcinoma, aiming to uncover potential protective effects. Through a case-control approach involving groups with reflux esophagitis, Barrett's esophagus, and esophageal adenocarcinoma, we assessed the dietary intake of antioxidants and their relationship with these conditions.

Our findings revealed that a higher overall antioxidant intake was linked to a reduced risk of esophageal adenocarcinoma. Specifically, individuals with the highest vitamin C intake had a significantly lower risk of developing this type of cancer. However, while vitamin C also appeared to reduce the risk of reflux esophagitis, we found no strong connection between vitamin C and Barrett's esophagus, nor with other antioxidants such as vitamin E, carotenoids, zinc, copper, or selenium.

This suggests that while antioxidants could play a role in lowering the risk of esophageal adenocarcinoma, they might be more influential in terms of progression rather than initiating reflux conditions. Overall, our study highlights the potential significance of dietary vitamin C in addressing reflux issues but points out limitations when it comes to other forms of esophageal disorders.
Read More

Most Useful Reviews

8.8
Relieves reflux
I use Vitamin C in large doses for health benefits and to ease constipation. Unlike others, this Vitamin C doesn’t cause reflux, and I need less of it. I can take it without worrying about the side effects, which makes it an excellent choice for me.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
8
Vitamin C aids omeprazole therapy
Antioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis.
Moderate relevance to reflux treatment
We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.

We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.

This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
Read More
7
Antioxidants may reduce cancer risk
Dietary antioxidant and mineral intake in humans is associated with reduced risk of esophageal adenocarcinoma but not reflux esophagitis or Barrett's esophagus.
Limited isolation of vitamin C effects
We studied how antioxidants, particularly vitamin C, relate to reflux esophagitis and esophageal adenocarcinoma, aiming to uncover potential protective effects. Through a case-control approach involving groups with reflux esophagitis, Barrett's esophagus, and esophageal adenocarcinoma, we assessed the dietary intake of antioxidants and their relationship with these conditions.

Our findings revealed that a higher overall antioxidant intake was linked to a reduced risk of esophageal adenocarcinoma. Specifically, individuals with the highest vitamin C intake had a significantly lower risk of developing this type of cancer. However, while vitamin C also appeared to reduce the risk of reflux esophagitis, we found no strong connection between vitamin C and Barrett's esophagus, nor with other antioxidants such as vitamin E, carotenoids, zinc, copper, or selenium.

This suggests that while antioxidants could play a role in lowering the risk of esophageal adenocarcinoma, they might be more influential in terms of progression rather than initiating reflux conditions. Overall, our study highlights the potential significance of dietary vitamin C in addressing reflux issues but points out limitations when it comes to other forms of esophageal disorders.
Read More

User Reviews

USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Relieves reflux
I use Vitamin C in large doses for health benefits and to ease constipation. Unlike others, this Vitamin C doesn’t cause reflux, and I need less of it. I can take it without worrying about the side effects, which makes it an excellent choice for me.
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