Last update
5/23/2025
Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 3 Reviews
8.3
Supplement Facts
Serving Size:  1 Softgel
Amount Per Serving
%DV
Proprietary Probiotic BlendProviding 1 billion CFU:Bifidobacterium longum BB536, B. bifidum/lactis Bb-02â„¢, B. breve M-16V, B. infantis M-63
15 mg
**

Top Medical Research Studies

8
Bifidobacterium lactis aids reflux recovery
We examined the effects of Bifidobacterium lactis as a complementary treatment for reflux esophagitis (RE) in a randomized, double-blind, placebo-controlled study. A total of 110 RE patients received rabeprazole while being supplemented with either Bifidobacterium or a placebo over 8 weeks.

Our findings showed that the probiotic group experienced quicker symptom relief and a longer time before symptoms returned, compared to the placebo. We also noted improvements in gut microbiota diversity following the treatment. Thus, Bifidobacterium lactis appears to provide significant benefits as an adjunct therapy for managing reflux symptoms.
Read More
In our exploration, we examined how Bifidobacterium lactis HN019 could influence gut transit time and gastrointestinal symptoms. We enrolled 100 adults with functional GI issues, splitting them into groups to receive either high-dose, low-dose, or placebo for two weeks.

We found that both treatment groups experienced significant reductions in gut transit times and a decrease in various GI symptoms. The placebo group did not show any notable improvements.

Overall, B. lactis HN019 seems effective in easing reflux-related symptoms and improving gut health.
Read More
9
Probiotic mixture eases constipation, reflux
We aimed to explore the effectiveness of a specific probiotic mixture called Ecologic®Relief in treating constipation among pregnant women. Over four weeks, participants reported significant improvements in their bowel habits, including increased defecation frequency and reduced sensations of obstruction and incomplete evacuation.

Importantly, we noted that the probiotic mixture also seemed to decrease reflux episodes from 60% to 20%. This suggests that not only does Ecologic®Relief help with constipation, but it may also provide relief from reflux symptoms during pregnancy. We believe more extensive studies will be beneficial to confirm these findings.
Read More

Most Useful Reviews

7.5
Settled stomach issues
64 people found this helpful
The Enzymatic Pearls Elite have been incredible for my stomach troubles. After undergoing chemotherapy, I dealt with IBS, bloating, gas, and acid reflux. I tried various remedies, but this product finally helped settle my stomach and relieve the pain. I highly recommend it, but note that not all their probiotics have the same formula. Good luck and happy tummy to you!
Read More
10
Reduced acid reflux
4 people found this helpful
Improved gut health and digestion. This product has helped me wean off prescription GERD medications after five or six years. The probiotics significantly improved my digestion and overall gut health. No more severe acid reflux! Before using this product, I took prescription-strength H2 blockers and PPIs, which had side effects. I wanted to explore alternatives, and after trying apple cider vinegar and other supplements without success, Nature's Way Probiotic Pearls changed everything. If I forget my probiotics while travelling, the acid reflux returns in days. Switching to other brands shows differences, perhaps due to this having a high 5-billion active probiotic count. Overall, it's a fantastic product that I highly recommend.
Read More
7.5
Reduced reflux significantly
1 people found this helpful
I like these enzymatic pearls. I can't compare them to other brands as I've never tried another, but they have really helped my acid reflux quite a bit.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
  • All Researches
9
Probiotic mixture eases constipation, reflux
We aimed to explore the effectiveness of a specific probiotic mixture called Ecologic®Relief in treating constipation among pregnant women. Over four weeks, participants reported significant improvements in their bowel habits, including increased defecation frequency and reduced sensations of obstruction and incomplete evacuation.

Importantly, we noted that the probiotic mixture also seemed to decrease reflux episodes from 60% to 20%. This suggests that not only does Ecologic®Relief help with constipation, but it may also provide relief from reflux symptoms during pregnancy. We believe more extensive studies will be beneficial to confirm these findings.
Read More
8
Bifidobacterium lactis aids reflux recovery
We examined the effects of Bifidobacterium lactis as a complementary treatment for reflux esophagitis (RE) in a randomized, double-blind, placebo-controlled study. A total of 110 RE patients received rabeprazole while being supplemented with either Bifidobacterium or a placebo over 8 weeks.

Our findings showed that the probiotic group experienced quicker symptom relief and a longer time before symptoms returned, compared to the placebo. We also noted improvements in gut microbiota diversity following the treatment. Thus, Bifidobacterium lactis appears to provide significant benefits as an adjunct therapy for managing reflux symptoms.
Read More
In our exploration, we examined how Bifidobacterium lactis HN019 could influence gut transit time and gastrointestinal symptoms. We enrolled 100 adults with functional GI issues, splitting them into groups to receive either high-dose, low-dose, or placebo for two weeks.

We found that both treatment groups experienced significant reductions in gut transit times and a decrease in various GI symptoms. The placebo group did not show any notable improvements.

Overall, B. lactis HN019 seems effective in easing reflux-related symptoms and improving gut health.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Settled stomach issues
64 people found this helpful
The Enzymatic Pearls Elite have been incredible for my stomach troubles. After undergoing chemotherapy, I dealt with IBS, bloating, gas, and acid reflux. I tried various remedies, but this product finally helped settle my stomach and relieve the pain. I highly recommend it, but note that not all their probiotics have the same formula. Good luck and happy tummy to you!
Read More
10
Reduced acid reflux
4 people found this helpful
Improved gut health and digestion. This product has helped me wean off prescription GERD medications after five or six years. The probiotics significantly improved my digestion and overall gut health. No more severe acid reflux! Before using this product, I took prescription-strength H2 blockers and PPIs, which had side effects. I wanted to explore alternatives, and after trying apple cider vinegar and other supplements without success, Nature's Way Probiotic Pearls changed everything. If I forget my probiotics while travelling, the acid reflux returns in days. Switching to other brands shows differences, perhaps due to this having a high 5-billion active probiotic count. Overall, it's a fantastic product that I highly recommend.
Read More
7.5
Reduced reflux significantly
1 people found this helpful
I like these enzymatic pearls. I can't compare them to other brands as I've never tried another, but they have really helped my acid reflux quite a bit.
Read More

Frequently Asked Questions

8
Bifidobacterium lactis aids reflux recovery
We examined the effects of Bifidobacterium lactis as a complementary treatment for reflux esophagitis (RE) in a randomized, double-blind, placebo-controlled study. A total of 110 RE patients received rabeprazole while being supplemented with either Bifidobacterium or a placebo over 8 weeks.

Our findings showed that the probiotic group experienced quicker symptom relief and a longer time before symptoms returned, compared to the placebo. We also noted improvements in gut microbiota diversity following the treatment. Thus, Bifidobacterium lactis appears to provide significant benefits as an adjunct therapy for managing reflux symptoms.
9
Probiotic mixture eases constipation, reflux
We aimed to explore the effectiveness of a specific probiotic mixture called Ecologic®Relief in treating constipation among pregnant women. Over four weeks, participants reported significant improvements in their bowel habits, including increased defecation frequency and reduced sensations of obstruction and incomplete evacuation.

Importantly, we noted that the probiotic mixture also seemed to decrease reflux episodes from 60% to 20%. This suggests that not only does Ecologic®Relief help with constipation, but it may also provide relief from reflux symptoms during pregnancy. We believe more extensive studies will be beneficial to confirm these findings.

References

  1. Gan L, Wang Y, Huang S, Zheng L, Feng Q, et al. Therapeutic Evaluation of subsp. MH-02 as an Adjunctive Treatment in Patients with Reflux Esophagitis: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2024;16. 10.3390/nu16030342
  2. de Milliano I, Tabbers MM, van der Post JA, Benninga MA. Is a multispecies probiotic mixture effective in constipation during pregnancy? 'A pilot study'. Nutr J. 2012;11:80. 10.1186/1475-2891-11-80
  3. Waller PA, Gopal PK, Leyer GJ, Ouwehand AC, Reifer C, et al. Dose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults. Scand J Gastroenterol. 2011;46:1057. 10.3109/00365521.2011.584895
image