Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 5 Reviews
8.9
Supplement Facts
Serving Size: 1 Vegetarian Tablet
Amount Per Serving
%DV
Vitamin C (as Ester-C® Calcium Ascorbate)
1,000 mg (1 g)
1,111%
Calcium (as Ester-C® Calcium Ascorbate)
108 mg
8%
Citrus Bioflavonoids ComplexCitrus Bioflavonoids (Citrus spp.) (fruit), Sweet Orange, Tangerine, Lime, Lemon, Acerola, Rutin, Hesperidin Complex (Citrus spp.) (fruit), Naturally Occurring Vitamin C Metabolites
200 mg
**
Top Medical Research Studies
8
We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
Read More
7
Antioxidants may reduce cancer risk
We studied how antioxidants, particularly vitamin C, relate to reflux esophagitis and esophageal adenocarcinoma, aiming to uncover potential protective effects. Through a case-control approach involving groups with reflux esophagitis, Barrett's esophagus, and esophageal adenocarcinoma, we assessed the dietary intake of antioxidants and their relationship with these conditions.
Our findings revealed that a higher overall antioxidant intake was linked to a reduced risk of esophageal adenocarcinoma. Specifically, individuals with the highest vitamin C intake had a significantly lower risk of developing this type of cancer. However, while vitamin C also appeared to reduce the risk of reflux esophagitis, we found no strong connection between vitamin C and Barrett's esophagus, nor with other antioxidants such as vitamin E, carotenoids, zinc, copper, or selenium.
This suggests that while antioxidants could play a role in lowering the risk of esophageal adenocarcinoma, they might be more influential in terms of progression rather than initiating reflux conditions. Overall, our study highlights the potential significance of dietary vitamin C in addressing reflux issues but points out limitations when it comes to other forms of esophageal disorders.
Our findings revealed that a higher overall antioxidant intake was linked to a reduced risk of esophageal adenocarcinoma. Specifically, individuals with the highest vitamin C intake had a significantly lower risk of developing this type of cancer. However, while vitamin C also appeared to reduce the risk of reflux esophagitis, we found no strong connection between vitamin C and Barrett's esophagus, nor with other antioxidants such as vitamin E, carotenoids, zinc, copper, or selenium.
This suggests that while antioxidants could play a role in lowering the risk of esophageal adenocarcinoma, they might be more influential in terms of progression rather than initiating reflux conditions. Overall, our study highlights the potential significance of dietary vitamin C in addressing reflux issues but points out limitations when it comes to other forms of esophageal disorders.
Read More
Most Useful Reviews
10
Improved health significantly
12 people found this helpful
Great product! Since I started taking these vitamin C capsules, I've felt much healthier. Initially, I took one a day but have increased it to two and I feel absolutely amazing! The best part is that I have severe acid reflux, so I've always been wary of vitamin C. This supplement provides me with plenty of usable vitamin C without any acid. I'm a Prime member, and as always, delivery was quick and packaging secure. I would definitely recommend it to a friend!
Read More
10
No reflux experienced
2 people found this helpful
I find Ester-C to be the best vitamin C as it uses calcium ascorbate, which prevents heartburn or reflux. With my sensitive stomach, I handle this product very well, and it contains no added sugar or harmful sweeteners. It’s worth noting that sugar can hinder vitamin C absorption, so this formulation is ideal.
Read More
10
No reflux worries
この製品は、逆流に悩むことなくビタミンCを摂取したい人に最適です。
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
- All Researches
8
We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
Read More
7
Antioxidants may reduce cancer risk
We studied how antioxidants, particularly vitamin C, relate to reflux esophagitis and esophageal adenocarcinoma, aiming to uncover potential protective effects. Through a case-control approach involving groups with reflux esophagitis, Barrett's esophagus, and esophageal adenocarcinoma, we assessed the dietary intake of antioxidants and their relationship with these conditions.
Our findings revealed that a higher overall antioxidant intake was linked to a reduced risk of esophageal adenocarcinoma. Specifically, individuals with the highest vitamin C intake had a significantly lower risk of developing this type of cancer. However, while vitamin C also appeared to reduce the risk of reflux esophagitis, we found no strong connection between vitamin C and Barrett's esophagus, nor with other antioxidants such as vitamin E, carotenoids, zinc, copper, or selenium.
This suggests that while antioxidants could play a role in lowering the risk of esophageal adenocarcinoma, they might be more influential in terms of progression rather than initiating reflux conditions. Overall, our study highlights the potential significance of dietary vitamin C in addressing reflux issues but points out limitations when it comes to other forms of esophageal disorders.
Our findings revealed that a higher overall antioxidant intake was linked to a reduced risk of esophageal adenocarcinoma. Specifically, individuals with the highest vitamin C intake had a significantly lower risk of developing this type of cancer. However, while vitamin C also appeared to reduce the risk of reflux esophagitis, we found no strong connection between vitamin C and Barrett's esophagus, nor with other antioxidants such as vitamin E, carotenoids, zinc, copper, or selenium.
This suggests that while antioxidants could play a role in lowering the risk of esophageal adenocarcinoma, they might be more influential in terms of progression rather than initiating reflux conditions. Overall, our study highlights the potential significance of dietary vitamin C in addressing reflux issues but points out limitations when it comes to other forms of esophageal disorders.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.9
- All Reviews
- Positive Reviews
- Negative Reviews
10
Improved health significantly
12 people found this helpful
Great product! Since I started taking these vitamin C capsules, I've felt much healthier. Initially, I took one a day but have increased it to two and I feel absolutely amazing! The best part is that I have severe acid reflux, so I've always been wary of vitamin C. This supplement provides me with plenty of usable vitamin C without any acid. I'm a Prime member, and as always, delivery was quick and packaging secure. I would definitely recommend it to a friend!
Read More
10
No reflux experienced
2 people found this helpful
I find Ester-C to be the best vitamin C as it uses calcium ascorbate, which prevents heartburn or reflux. With my sensitive stomach, I handle this product very well, and it contains no added sugar or harmful sweeteners. It’s worth noting that sugar can hinder vitamin C absorption, so this formulation is ideal.
Read More
10
No reflux worries
この製品は、逆流に悩むことなくビタミンCを摂取したい人に最適です。
Read More
10
Effective without reflux
This is a fantastic form of vitamin C with bioflavonoids for improved absorption. The capsule contains powder and is easy to take, plus I haven’t experienced any reflux.
Read More
7.5
Amazing for reflux
My regular vitamin C caused reflux, but this Ester-C is exceptional. I ordered it due to a local shortage and have been pleased with the results. However, the capsules are somewhat large, making swallowing a bit challenging. I would certainly recommend this product!
Read More
Frequently Asked Questions
10
No reflux experienced
2 people found this helpful
I find Ester-C to be the best vitamin C as it uses calcium ascorbate, which prevents heartburn or reflux. With my sensitive stomach, I handle this product very well, and it contains no added sugar or harmful sweeteners. It’s worth noting that sugar can hinder vitamin C absorption, so this formulation is ideal.
10
No reflux worries
この製品は、逆流に悩むことなくビタミンCを摂取したい人に最適です。
10
Effective without reflux
This is a fantastic form of vitamin C with bioflavonoids for improved absorption. The capsule contains powder and is easy to take, plus I haven’t experienced any reflux.
7.5
Amazing for reflux
My regular vitamin C caused reflux, but this Ester-C is exceptional. I ordered it due to a local shortage and have been pleased with the results. However, the capsules are somewhat large, making swallowing a bit challenging. I would certainly recommend this product!
7
Antioxidants may reduce cancer risk
We studied how antioxidants, particularly vitamin C, relate to reflux esophagitis and esophageal adenocarcinoma, aiming to uncover potential protective effects. Through a case-control approach involving groups with reflux esophagitis, Barrett's esophagus, and esophageal adenocarcinoma, we assessed the dietary intake of antioxidants and their relationship with these conditions.
Our findings revealed that a higher overall antioxidant intake was linked to a reduced risk of esophageal adenocarcinoma. Specifically, individuals with the highest vitamin C intake had a significantly lower risk of developing this type of cancer. However, while vitamin C also appeared to reduce the risk of reflux esophagitis, we found no strong connection between vitamin C and Barrett's esophagus, nor with other antioxidants such as vitamin E, carotenoids, zinc, copper, or selenium.
This suggests that while antioxidants could play a role in lowering the risk of esophageal adenocarcinoma, they might be more influential in terms of progression rather than initiating reflux conditions. Overall, our study highlights the potential significance of dietary vitamin C in addressing reflux issues but points out limitations when it comes to other forms of esophageal disorders.
Our findings revealed that a higher overall antioxidant intake was linked to a reduced risk of esophageal adenocarcinoma. Specifically, individuals with the highest vitamin C intake had a significantly lower risk of developing this type of cancer. However, while vitamin C also appeared to reduce the risk of reflux esophagitis, we found no strong connection between vitamin C and Barrett's esophagus, nor with other antioxidants such as vitamin E, carotenoids, zinc, copper, or selenium.
This suggests that while antioxidants could play a role in lowering the risk of esophageal adenocarcinoma, they might be more influential in terms of progression rather than initiating reflux conditions. Overall, our study highlights the potential significance of dietary vitamin C in addressing reflux issues but points out limitations when it comes to other forms of esophageal disorders.
8
We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
References
- Murphy SJ, Anderson LA, Ferguson HR, Johnston BT, Watson PR, et al. Dietary antioxidant and mineral intake in humans is associated with reduced risk of esophageal adenocarcinoma but not reflux esophagitis or Barrett's esophagus. J Nutr. 2010;140:1757. doi:10.3945/jn.110.124362
- Kohler JE, Blass AL, Liu J, Tai K, Soybel DI. Antioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis. Free Radic Biol Med. 2010;49:786. doi:10.1016/j.freeradbiomed.2010.05.034
