' 
SCIENTIFIC SCORE
Questionable
Based on 16 Researches
6.5
USERS' SCORE
Good
Based on 1 Review
8.6
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Calories from Fat
10
Total Fat
1.5 g
2%†
Evening Primrose Oil (supplying 10% (130 mg) gamma-linolenic acid)
1300 mg
†
Top Medical Research Studies
9
Evening primrose oil shows promise
A long-term study on the use of evening primrose oil (Efamol) in atopic children.
Relevant study on eczema treatment
We explored the effects of evening primrose oil on children's atopic eczema over a 20-week period. Initially, we observed that kids who took this oil showed significant improvement in their skin conditions after just four weeks. Remarkably, those benefits continued throughout the entire treatment duration. Along with these clinical improvements, we also noted changes in the fatty acid composition in the children's blood cells. Despite these positive findings, it's worth noting that opinions about the effectiveness of evening primrose oil vary among researchers, making the overall consensus somewhat unclear.
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7
Evening Primrose Oil effective for eczema
Effect of Evening Primrose Oil on Korean Patients With Mild Atopic Dermatitis: A Randomized, Double-Blinded, Placebo-Controlled Clinical Study.
Study relevant for eczema treatment
We explored the effects of evening primrose oil (EPO) on Korean patients with mild atopic dermatitis through a well-structured randomized, double-blinded, placebo-controlled clinical study.
Fifty participants took either EPO or a placebo for four months. By the end of the study, those who received EPO showed significant improvements in their eczema symptoms compared to the placebo group.
While some slight improvements in skin hydration and transepidermal water loss were noted, they weren't statistically significant. Overall, we found EPO to be a safe and effective option for managing mild atopic dermatitis.
Fifty participants took either EPO or a placebo for four months. By the end of the study, those who received EPO showed significant improvements in their eczema symptoms compared to the placebo group.
While some slight improvements in skin hydration and transepidermal water loss were noted, they weren't statistically significant. Overall, we found EPO to be a safe and effective option for managing mild atopic dermatitis.
Read More
7
Evening primrose oil shows promise for eczema
Dose-dependent effects of evening primrose oil in children and adolescents with atopic dermatitis.
Moderate relevance of findings
We examined the effects of evening primrose oil on eczema by studying 40 patients over eight weeks. The participants were split into two groups: one receiving 160 mg daily and the other 320 mg twice daily.
Both groups showed a reduction in eczema symptoms as measured by the Eczema Area Severity Index (EASI) scores. Interestingly, while the higher dose group had more significant fatty acid level improvements, both doses appeared effective in managing eczema symptoms.
Overall, this study suggests that evening primrose oil may help alleviate eczema without notable side effects.
Both groups showed a reduction in eczema symptoms as measured by the Eczema Area Severity Index (EASI) scores. Interestingly, while the higher dose group had more significant fatty acid level improvements, both doses appeared effective in managing eczema symptoms.
Overall, this study suggests that evening primrose oil may help alleviate eczema without notable side effects.
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Most Useful Reviews
9.5
Eczema cleared fast
Trying new supplements can be daunting due to potential side effects, but I've trusted good brands. I decided to try evening primrose oil for my eczema, which I experience from time to time in colder weather. I didn't expect results quickly, but my eczema cleared up after just two days of use! My skin feels smoother, and my face is clearer too. I plan to reorder this brand!
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 16 Researches
6.5
- All Researches
9
Evening primrose oil shows promise
Meta-analysis of placebo-controlled studies of the efficacy of Epogam in the treatment of atopic eczema. Relationship between plasma essential fatty acid changes and clinical response.
Moderate relevance to eczema treatment
We examined nine controlled trials to understand how evening primrose oil, specifically Epogam, impacts atopic eczema.
Both patients and doctors noted significant improvements in skin symptoms, such as dryness and itchiness, especially in the initial parallel studies.
However, while improvements were observed in crossover trials, the difference compared to placebo didn’t reach statistical significance for doctor scores.
Importantly, patients experienced a notable reduction in itch severity, underscoring Epogam's potential benefits for those struggling with eczema.
Both patients and doctors noted significant improvements in skin symptoms, such as dryness and itchiness, especially in the initial parallel studies.
However, while improvements were observed in crossover trials, the difference compared to placebo didn’t reach statistical significance for doctor scores.
Importantly, patients experienced a notable reduction in itch severity, underscoring Epogam's potential benefits for those struggling with eczema.
Read More
9
Evening primrose oil shows promise
Evening primrose oil (Efamol) in the treatment of children with atopic eczema.
Significant benefit in children
We investigated the effects of evening primrose oil on children with atopic eczema. In a focused study, 24 children were divided into two groups: one received a higher dose of evening primrose oil, while the other got a placebo.
After just four weeks, we observed significant improvement in eczema symptoms among those treated with evening primrose oil compared to the placebo group. This suggests that evening primrose oil can positively influence children's eczema, potentially due to its impact on essential fatty acids.
After just four weeks, we observed significant improvement in eczema symptoms among those treated with evening primrose oil compared to the placebo group. This suggests that evening primrose oil can positively influence children's eczema, potentially due to its impact on essential fatty acids.
Read More
9
Evening primrose oil shows promise
A long-term study on the use of evening primrose oil (Efamol) in atopic children.
Relevant study on eczema treatment
We explored the effects of evening primrose oil on children's atopic eczema over a 20-week period. Initially, we observed that kids who took this oil showed significant improvement in their skin conditions after just four weeks. Remarkably, those benefits continued throughout the entire treatment duration. Along with these clinical improvements, we also noted changes in the fatty acid composition in the children's blood cells. Despite these positive findings, it's worth noting that opinions about the effectiveness of evening primrose oil vary among researchers, making the overall consensus somewhat unclear.
Read More
8
Anti-inflammatory potential of EPO
Long-chain fatty alcohols from evening primrose oil inhibit the inflammatory response in murine peritoneal macrophages.
Moderate relevance to eczema treatment
The study explored the anti-inflammatory effects of long-chain fatty alcohols derived from evening primrose oil (EPO). We discovered that these compounds reduced nitric oxide production and curbed the secretion of certain inflammatory cytokines in lab tests using murine macrophages.
However, while the results point to the potential benefits of EPO in managing inflammation, this study primarily involved in vitro analyses, meaning further research is needed to establish its effectiveness specifically for eczema in humans. Overall, evening primrose oil shows promise, but significant clinical benefits for eczema should be approached with caution.
However, while the results point to the potential benefits of EPO in managing inflammation, this study primarily involved in vitro analyses, meaning further research is needed to establish its effectiveness specifically for eczema in humans. Overall, evening primrose oil shows promise, but significant clinical benefits for eczema should be approached with caution.
Read More
8
Mixed results on evening primrose oil
Treatment of atopic eczema with evening primrose oil: rationale and clinical results.
Not definitive; further study required
We explored the effectiveness of evening primrose oil as a treatment for atopic eczema. Controlled clinical trials displayed marked improvements in patients, with reductions in inflammation, dryness, and overall eczema severity compared to the control group. Although some meta-analyses support these positive findings, conflicting results from crossover trials regarding itching relief suggest that more research is necessary.
Overall, evening primrose oil appears to be a safe option, but we still need more studies to fully understand its benefits and efficacy.
Overall, evening primrose oil appears to be a safe option, but we still need more studies to fully understand its benefits and efficacy.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Eczema cleared fast
Trying new supplements can be daunting due to potential side effects, but I've trusted good brands. I decided to try evening primrose oil for my eczema, which I experience from time to time in colder weather. I didn't expect results quickly, but my eczema cleared up after just two days of use! My skin feels smoother, and my face is clearer too. I plan to reorder this brand!
Read More
