Last update
4/7/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 1 Level Teaspoon (approx. 2 g)
Serving Per Container: About 85
Amount Per Serving
%DV
Calories
10
Total Carbohydrate
2 g
<1%*
Total Sugars
2 g
†
Organic D-Mannose
2 g (2,000 mg)
†
Top Medical Research Studies
8
We explored how D-mannose could help prevent urinary tract infections and discomfort in patients undergoing cystoscopy. In a well-structured study with 32 patients, those receiving D-mannose experienced significantly fewer UTIs and less severe urinary symptoms compared to those who did not receive treatment.
While the treatment showed promise by reducing the number of infections and pain, no major difference was found in overall quality of life scores between the groups. This indicates D-mannose could be beneficial for specific discomforts related to the procedure.
While the treatment showed promise by reducing the number of infections and pain, no major difference was found in overall quality of life scores between the groups. This indicates D-mannose could be beneficial for specific discomforts related to the procedure.
Read More
7
Yeast impacts sperm quality negatively
We examined how certain yeast strains affect male fertility, particularly by observing their influence on sperm quality.
Our research revealed that these yeast strains altered conventional sperm parameters like viability and motility when incubated together.
Interestingly, while functional parameters showed changes, these were not statistically significant. However, pretreating sperm with mannose did reduce the impact of the yeast, suggesting that the yeast's interaction with sperm is likely mediated through mannose receptors.
Our research revealed that these yeast strains altered conventional sperm parameters like viability and motility when incubated together.
Interestingly, while functional parameters showed changes, these were not statistically significant. However, pretreating sperm with mannose did reduce the impact of the yeast, suggesting that the yeast's interaction with sperm is likely mediated through mannose receptors.
Read More
4
D-mannose has limited preventive effects
We considered how D-mannose and other lifestyle changes might help prevent recurrent urinary tract infections. Our review looked into various preventative measures, including hygiene and diet.
We found that D-mannose can potentially help by preventing harmful bacteria from sticking to the urinary tract. However, its effectiveness may vary based on the dosage. While these methods are generally well-tolerated, they are not guaranteed solutions.
We concluded that a mix of dietary adjustments and proper hydration could serve as an alternative to long-term antibiotic treatment.
We found that D-mannose can potentially help by preventing harmful bacteria from sticking to the urinary tract. However, its effectiveness may vary based on the dosage. While these methods are generally well-tolerated, they are not guaranteed solutions.
We concluded that a mix of dietary adjustments and proper hydration could serve as an alternative to long-term antibiotic treatment.
Read More
Most Useful Reviews
9
No infections
Excellent product! My husband endured severe bladder infections until we began using D-Mannose. He hasn't had any since!
Read More
7.5
Effective taste
I find it effective and it has significantly reduced my urinary tract infections. Additionally, it has a pleasant sweet taste.
Read More
7.5
Job well done
Really does the job, helping with urinary tract infections and bladder inflammation. It’s a good alternative to antibiotics.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
- All Researches
8
We explored how D-mannose could help prevent urinary tract infections and discomfort in patients undergoing cystoscopy. In a well-structured study with 32 patients, those receiving D-mannose experienced significantly fewer UTIs and less severe urinary symptoms compared to those who did not receive treatment.
While the treatment showed promise by reducing the number of infections and pain, no major difference was found in overall quality of life scores between the groups. This indicates D-mannose could be beneficial for specific discomforts related to the procedure.
While the treatment showed promise by reducing the number of infections and pain, no major difference was found in overall quality of life scores between the groups. This indicates D-mannose could be beneficial for specific discomforts related to the procedure.
Read More
7
Yeast impacts sperm quality negatively
We examined how certain yeast strains affect male fertility, particularly by observing their influence on sperm quality.
Our research revealed that these yeast strains altered conventional sperm parameters like viability and motility when incubated together.
Interestingly, while functional parameters showed changes, these were not statistically significant. However, pretreating sperm with mannose did reduce the impact of the yeast, suggesting that the yeast's interaction with sperm is likely mediated through mannose receptors.
Our research revealed that these yeast strains altered conventional sperm parameters like viability and motility when incubated together.
Interestingly, while functional parameters showed changes, these were not statistically significant. However, pretreating sperm with mannose did reduce the impact of the yeast, suggesting that the yeast's interaction with sperm is likely mediated through mannose receptors.
Read More
4
D-mannose has limited preventive effects
We considered how D-mannose and other lifestyle changes might help prevent recurrent urinary tract infections. Our review looked into various preventative measures, including hygiene and diet.
We found that D-mannose can potentially help by preventing harmful bacteria from sticking to the urinary tract. However, its effectiveness may vary based on the dosage. While these methods are generally well-tolerated, they are not guaranteed solutions.
We concluded that a mix of dietary adjustments and proper hydration could serve as an alternative to long-term antibiotic treatment.
We found that D-mannose can potentially help by preventing harmful bacteria from sticking to the urinary tract. However, its effectiveness may vary based on the dosage. While these methods are generally well-tolerated, they are not guaranteed solutions.
We concluded that a mix of dietary adjustments and proper hydration could serve as an alternative to long-term antibiotic treatment.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
No infections
Excellent product! My husband endured severe bladder infections until we began using D-Mannose. He hasn't had any since!
Read More
7.5
Effective taste
I find it effective and it has significantly reduced my urinary tract infections. Additionally, it has a pleasant sweet taste.
Read More
7.5
Job well done
Really does the job, helping with urinary tract infections and bladder inflammation. It’s a good alternative to antibiotics.
Read More
Frequently Asked Questions
References
- Quattrone C, Manfredi C, Napolitano L, Ferraro A, Distefano C, et al. D-Mannose Plus to Prevent Urinary Tract Infections and Discomfort after Cystoscopy: A Single-Center Prospective Randomized Pilot Study. Medicina (Kaunas). 2023;59. 10.3390/medicina59061165
- Castrillón-Duque EX, Puerta Suárez J, Cardona Maya WD. Yeast and Fertility: Effects of Activity of spp. on Sperm Quality. J Reprod Infertil. 2018;19:49. PubMed
- Armelle J. [Recurrent cystisis: No medicine preventive means]. Prog Urol. 2017;27:823. 10.1016/j.purol.2017.09.006
Data last updated:
