We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
4
Magnesium shows limited sleep benefits
Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis.
We explored the effects of magnesium supplementation on insomnia in older adults through a systematic review and meta-analysis. Our investigation included several studies that compared magnesium with a placebo or no treatment.
We found three randomized control trials involving 151 older adults across three countries. The pooled results indicated that individuals taking magnesium had a notable decrease in sleep onset latency, averaging a reduction of 17.36 minutes compared to those on placebo. However, the improvement in total sleep time, which increased by 16.06 minutes in the magnesium group, did not reach statistical significance.
Despite these findings, we must emphasize that the overall quality of the research is below standards necessary for making firm recommendations. All studies reviewed showed a moderate to high risk of bias, and the evidence quality ranged from low to very low. Nonetheless, magnesium is an affordable and widely accessible option for those struggling with insomnia symptoms, suggesting it may be a reasonable consideration for some older adults.
Read More
8
Magnesium may reduce daytime sleepiness
Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up.
We set out to explore how dietary magnesium might impact symptoms of insomnia, such as falling asleep during the day and snoring at night. Our study included a significant sample of 1,487 adults from the Jiangsu Nutrition Study, which allowed us to gather valuable information about their magnesium intake and sleep experiences. Over five years, we assessed participants' magnesium consumption through detailed food records and later examined their sleep patterns via a questionnaire.
Our findings revealed that the average magnesium intake among participants was 332.5 mg per day. Interestingly, we found that around 5.3% reported falling asleep during the day, 13.2% faced daytime sleepiness, and 35.7% experienced snoring at night. Rising through the quartiles of magnesium intake, we observed a promising decrease in the chance of women experiencing daytime falling asleep; however, this effect wasn’t mirrored in men. It’s crucial to note that we didn’t find significant associations between magnesium intake and daytime sleepiness or night snoring for either gender.
Overall, it seems that dietary magnesium might offer long-term benefits in reducing daytime sleepiness in women, while more research could clarify its effects on other symptoms. This makes magnesium an interesting dietary consideration for those seeking to improve their sleep quality.
Read More
Most Useful Reviews
9
Reduced insomnia
125 people found this helpful
Excellent support for the nervous system. Since taking this magnesium supplement, I’m much calmer and my insomnia has improved significantly. Unlike other magnesium products that caused nausea, this one works perfectly. I continue to take it monthly.
Read More
10
Sleep restoration
74 people found this helpful
This magnesium in citrate form has improved my sleep. I used to struggle with insomnia for years, but now I sleep through the night and wake refreshed. I've ordered it multiple times now and will continue.
Read More
9
Eliminated insomnia
24 people found this helpful
Very Effective Against Leg and Foot Cramps. This product significantly improved my leg and foot cramps at night and notably eliminated my insomnia. Instead of tossing and turning for hours, I now fall asleep within 20 minutes. I no longer require Melatonin or Ambien.
We explored the potential benefits of a supplement containing magnesium, melatonin, and vitamin B complex in treating insomnia. The study involved 60 patients diagnosed with insomnia, who were divided into a study group and a control group. Over three months, the study group received a daily dose of the supplement, while the control group did not receive it.
At the start, both groups had similar levels of insomnia, indicated by their scores on the Athens insomnia scale. However, after three months of supplementation, the study group showed a significant improvement, with their insomnia scores decreasing, indicating mild insomnia. In contrast, the control group’s scores remained stable, suggesting they continued to experience moderate insomnia.
Although magnesium was part of the supplement, the study design makes it challenging to isolate its specific effects on insomnia. Nevertheless, we observed that combining magnesium with melatonin and vitamin B complex potentially enhances sleep quality for those struggling with insomnia.
Read More
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
9
Magnesium may aid sleep quality
The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial in a long-term care facility in Italy to explore whether nightly doses of melatonin, magnesium, and zinc could benefit residents suffering from primary insomnia. Our study involved 43 participants, who were either given a combined supplement of these nutrients or a placebo for eight weeks.
The primary objective was to measure sleep quality using the Pittsburgh Sleep Quality Index, while we also considered secondary indicators like daytime sleepiness and overall quality of life. The results revealed that the combined approach of melatonin, magnesium, and zinc appeared to improve both sleep and quality of life for residents struggling with insomnia.
However, since magnesium was tested alongside two other supplements, we cannot clearly attribute the benefits directly to magnesium alone. Overall, the findings suggest a positive effect on sleep quality and well-being for long-term care residents dealing with insomnia, but we must be cautious in isolating each nutrient's individual effectiveness.
Read More
8
Magnesium improves insomnia in diabetes
Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
We conducted a randomized controlled trial focusing on individuals with diabetes who struggle with insomnia. Over two months, we examined the effects of magnesium and potassium supplementation on sleep quality and hormone levels. Our study included 320 patients, and after follow-up, 290 patients completed the trial. We assessed insomnia severity using the Insomnia Severity Index and analyzed changes in melatonin and cortisol levels, which are key sleep hormones.
Our findings indicated that magnesium supplementation—whether alone or in combination with potassium—had a notable positive impact. Participants who received magnesium and potassium demonstrated significant improvements in both insomnia severity and sleep hormone levels. It was exciting to see how these supplements could enhance sleep duration and quality in those facing the dual challenges of insomnia and diabetes.
Although the combination of magnesium and potassium was effective, we recognize that this limits a clear assessment of magnesium's isolated effects. Nevertheless, our research adds valuable insights on how these minerals may play a role in managing insomnia among diabetic patients.
Read More
8
Magnesium may aid post-surgery insomnia
Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial.
We conducted a study to explore how magnesium affects insomnia in patients undergoing lumbar fixation surgery. Our research involved 80 participants, divided into two groups: one received conventional general anesthesia supplemented with magnesium sulfate, while the other had standard anesthesia without magnesium.
We assessed various factors, including insomnia severity using the Insomnia Severity Index and post-operative delirium through the Memorial Delirium Assessment Scale. Interestingly, our findings indicated a significant relationship between the administration of magnesium and reduced instances of post-operative insomnia.
This suggests that magnesium may be beneficial in easing sleep disturbances experienced by some patients after surgery. However, we also noted variations due to other factors like pain and depression, which could influence the overall results.
While the relationship is promising, it’s essential to recognize that there may be multiple factors at play that contribute to insomnia post-surgery. Overall, our evaluation presents magnesium as a potentially helpful option for enhancing sleep quality in these patients.
Excellent support for the nervous system. Since taking this magnesium supplement, I’m much calmer and my insomnia has improved significantly. Unlike other magnesium products that caused nausea, this one works perfectly. I continue to take it monthly.
Read More
10
Sleep restoration
74 people found this helpful
This magnesium in citrate form has improved my sleep. I used to struggle with insomnia for years, but now I sleep through the night and wake refreshed. I've ordered it multiple times now and will continue.
Read More
9
Eliminated insomnia
24 people found this helpful
Very Effective Against Leg and Foot Cramps. This product significantly improved my leg and foot cramps at night and notably eliminated my insomnia. Instead of tossing and turning for hours, I now fall asleep within 20 minutes. I no longer require Melatonin or Ambien.
Read More
9
Relief from convulsions
7 people found this helpful
I've dealt with convulsions all my life. After COVID, they worsened along with insomnia. This magnesium, taken with vitamin B6 and potassium, helped significantly, and I felt improvement within a week. Highly recommend!
Read More
9
Better sleep
4 people found this helpful
My sleep has improved, and I feel more relaxed now. Low magnesium levels can lead to insomnia and anxiety, but this supplement normalises my mood. I take one capsule daily and feel much better overall.
Insomnia is a common sleep disorder characterized by the inability to fall asleep, stay asleep, or wake up too early and not be able to go back to sleep. Individuals experiencing insomnia may find that it affects their daytime functioning, leading to issues such as fatigue, mood disturbances, and difficulty concentrating. Insomnia can be classified into two main types: acute insomnia, which lasts for a short period often triggered by stress or life changes, and chronic insomnia, which occurs at least three times a week for three months or longer, and may require more in-depth evaluation and treatment.
Numerous factors can contribute to insomnia, including stress, anxiety, poor sleep habits, medical conditions, and the use of certain medications. Treatment for insomnia typically involves a combination of lifestyle changes, cognitive behavioral therapy for insomnia (CBT-I), and sometimes medication. Establishing a consistent sleep routine, creating a comfortable sleep environment, and practicing relaxation techniques can help improve sleep quality. If insomnia persists, it is advisable to consult a healthcare professional for proper diagnosis and customized treatment options.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium is often touted as a natural remedy for improving sleep quality and managing insomnia. This essential mineral plays a crucial role in various bodily functions, including the regulation of neurotransmitters that send signals throughout the nervous system and brain. Some studies suggest that magnesium may assist in promoting relaxation by helping to regulate melatonin, a hormone responsible for sleep-wake cycles. Additionally, it may help reduce anxiety and stress, which are common culprits of sleep disturbances.
While many people report improved sleep after incorporating magnesium supplements or magnesium-rich foods—like leafy greens, nuts, and whole grains—into their diets, the scientific evidence is mixed. More research is needed to definitively establish its effectiveness in treating insomnia. If you're considering magnesium supplements, it's always best to consult with a healthcare professional to determine the appropriate dosage and ensure that it won’t interact with any medications you may be taking. Overall, while magnesium may offer some benefits for sleep, it is most effective when used as part of a comprehensive approach to improving sleep hygiene.
Based on user reviews, the time it typically takes to see results from magnesium supplements for insomnia varies among individuals. Many users report noticing improvements in their sleep quality within a week. For instance, one reviewer mentioned feeling significant improvement with insomnia after just one week of taking magnesium alongside other vitamins (Read Review). Others, however, imply that noticeable effects can take longer, with improvements becoming evident after two to three weeks of consistent use (Read Review).
Overall, users agree that incorporating magnesium into their evening routine has helped mitigate insomnia, often enhancing their ability to fall asleep and stay asleep throughout the night. Several reviews highlight that it takes about two weeks to start feeling the calming effects and to see a reduction in sleep interruptions (Read Review). Therefore, while some may experience quicker results, others might need a few weeks for the full benefits to manifest.
Research indicates that magnesium supplementation may be beneficial for alleviating insomnia symptoms in various contexts. A systematic review and meta-analysis involving multiple studies showed that magnesium could improve sleep quality, particularly in older adults and those experiencing post-surgery insomnia. For instance, in a clinical trial with 46 older participants, magnesium supplementation was associated with significant improvements in sleep efficiency and insomnia severity, hinting at its potential role in sleep quality enhancement ([8]). Additionally, another study focusing on postoperative patients also identified a reduction in insomnia severity linked to magnesium treatment ([2]).
However, while these findings are promising, the varying quality and design of the studies make it hard to draw firm conclusions. Some studies show mixed results, and factors like supplemental form, dosage, and participant characteristics can influence outcomes. For example, one review found that among 15 studies, five showed a positive effect on sleep quality with magnesium, while others did not find significant benefits ([3]). Therefore, while magnesium appears to be a reasonable option for those struggling with insomnia, more large-scale and well-designed trials are necessary to establish clearer guidelines on its use in sleep disorder treatments.
Based on user reviews, many individuals have reported significant improvements in their symptoms of insomnia and related issues after incorporating magnesium into their routines. Users consistently express that their quality of sleep has greatly enhanced, with several mentioning the ability to sleep through the night without frequent awakenings. For instance, one reviewer noted, "I can now fall asleep in under 20 minutes" after struggling with insomnia for over a decade (Read Review). Other users have observed an increase in their overall sense of calm and reduced feelings of anxiety, further contributing to better sleep quality (Read Review).
In addition to improvements in sleep, some reviewers have reported additional benefits, such as reduced muscle cramps and enhanced relaxation during stressful moments (Read Review). Several users have specifically mentioned that magnesium has alleviated their dependency on sleep medications, allowing for a more natural sleep cycle (Read Review). However, it’s important to note that results can vary widely among individuals; while some see changes within days, others may require a longer period to experience full benefits (Read Review). Overall, the consensus is clear: many users find magnesium to be a valuable asset in managing sleep issues and enhancing their overall wellbeing.
Based on user reviews, combining magnesium with other supplements for handling insomnia appears to yield positive results for many individuals. Users have reported that taking magnesium alongside vitamin B6 and potassium helped significantly improve their sleep quality and alleviate symptoms related to insomnia and anxiety. One reviewer highlighted their remarkable progress, stating they felt improvements within just a week of this combination (Read Review). Others have mentioned using magnesium in conjunction with melatonin to enhance their sleep experience further, with one user noting the effectiveness of this combination for achieving a restful slumber (Read Review).
Furthermore, several reviewers emphasized the overall calming effects of magnesium, stating it helps mitigate not just insomnia but also feelings of stress and anxiety. This calming effect seems to be magnified when magnesium is taken with other supportive supplements, promoting a more stable and restful sleep. Users reported a notable decrease in sleep disturbances and an overall increase in their ability to manage stressful situations when following a routine that includes magnesium plus other vitamins (Read Review). Overall, the blend of magnesium with other supplements seems to be a popular strategy among users seeking relief from insomnia.
According to research, the optimal dose of magnesium for treating insomnia isn't definitively established due to variability across studies. However, one study involving older adults indicated beneficial effects with a daily supplementation of 500 mg for eight weeks, which resulted in significant improvements in sleep quality and insomnia severity [8]. Additionally, a review of multiple clinical studies suggests that magnesium supplementation could enhance sleep quality, particularly for individuals starting with low magnesium levels, although specific dosages were inconsistent across trials [3].
Another study reported that an average intake of around 332.5 mg of magnesium per day correlated with improved sleep experiences among participants [6]. While some evidence points to dosages of around 300-500 mg being effective, further large-scale trials are needed to conclusively determine the optimal dosage for treating insomnia. Nevertheless, magnesium remains a promising option for those seeking natural remedies for sleep disturbances.
9
Relief from convulsions
7 people found this helpful
I've dealt with convulsions all my life. After COVID, they worsened along with insomnia. This magnesium, taken with vitamin B6 and potassium, helped significantly, and I felt improvement within a week. Highly recommend!
9
Reduced irritability
1 people found this helpful
My concentration and sleep improved with this magnesium, combating feelings of anxiety, irritability, and insomnia. After two weeks, I felt calmer and less prone to wakefulness at night.
7.5
Improved sleep
718 people found this helpful
Calm, just calm. I take 400 mg of magnesium daily, and within weeks, my insomnia has improved. The citrate form can be weak, but I've noticed fewer twitches at night, and my sleep quality is more stable. Magnesium has helped me handle stress more easily, and while insomnia still occurs, I no longer wake due to twitching.
7.5
Faster sleep
65 people found this helpful
After over a decade of insomnia, I can now fall asleep in under 20 minutes. Though I still wake occasionally, it’s significantly less frequent. I no longer rely on sleeping pills, and I hope this helps others with insomnia too.
9
Anxiety relief
1 people found this helpful
Magnesium is essential for our family. We've consumed many cans, with no side effects noted. We each take between 400-800 mg as needed. Since magnesium is quickly depleted in the body, I ensure we're stocked up, as deficiency leads to anxiety and irritability. This product has really helped me with my personal anxiety and mood swings.
9
Normal sleeps
2 people found this helpful
I was very pleased with Magnesium Citrate from NOW. It helped with my insomnia, allowing me to react calmly in stressful situations.
9
Essential for sleep
1 people found this helpful
I absolutely love this product. It’s always by my bedside and I recommend it to anyone dealing with constipation, excessive coffee consumption, or insomnia. I take it with melatonin for a restful sleep and use it after the gym to relax tense muscles. The quality and packaging are excellent.
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
8
Magnesium may aid post-surgery insomnia
Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial.
We conducted a study to explore how magnesium affects insomnia in patients undergoing lumbar fixation surgery. Our research involved 80 participants, divided into two groups: one received conventional general anesthesia supplemented with magnesium sulfate, while the other had standard anesthesia without magnesium.
We assessed various factors, including insomnia severity using the Insomnia Severity Index and post-operative delirium through the Memorial Delirium Assessment Scale. Interestingly, our findings indicated a significant relationship between the administration of magnesium and reduced instances of post-operative insomnia.
This suggests that magnesium may be beneficial in easing sleep disturbances experienced by some patients after surgery. However, we also noted variations due to other factors like pain and depression, which could influence the overall results.
While the relationship is promising, it’s essential to recognize that there may be multiple factors at play that contribute to insomnia post-surgery. Overall, our evaluation presents magnesium as a potentially helpful option for enhancing sleep quality in these patients.
7
Magnesium may improve insomnia
Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.
We examined the potential benefits of magnesium supplements for improving sleep quality through a detailed analysis of existing clinical studies. Our systematic review focused specifically on trials investigating how magnesium affects insomnia, which have gained popularity among people seeking natural remedies for sleep problems.
A total of 15 relevant studies were reviewed. Among these, eight studies looked specifically at sleep-related outcomes, often employing the Pittsburgh Sleep Quality Index (PSQI) to measure improvements. The results were promising—five out of the eight studies indicated that magnesium supplementation led to better sleep quality.
However, it's important to note that not all studies observed benefits; two showed no significant improvements, and one provided mixed results. Many of these studies varied in the dosage, type of magnesium used, and overall participant numbers, which made it challenging to draw firm conclusions. Still, the general trend suggests that magnesium could indeed be helpful, especially for those who start with low magnesium levels.
Ultimately, while the findings lean towards positive, further large-scale, randomized trials are necessary to confirm the effectiveness of specific magnesium formulations and dosages in treating insomnia. We take these outcomes seriously, considering them a first step towards understanding how this mineral can help those struggling with sleep issues.
8
Magnesium may reduce daytime sleepiness
Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up.
We set out to explore how dietary magnesium might impact symptoms of insomnia, such as falling asleep during the day and snoring at night. Our study included a significant sample of 1,487 adults from the Jiangsu Nutrition Study, which allowed us to gather valuable information about their magnesium intake and sleep experiences. Over five years, we assessed participants' magnesium consumption through detailed food records and later examined their sleep patterns via a questionnaire.
Our findings revealed that the average magnesium intake among participants was 332.5 mg per day. Interestingly, we found that around 5.3% reported falling asleep during the day, 13.2% faced daytime sleepiness, and 35.7% experienced snoring at night. Rising through the quartiles of magnesium intake, we observed a promising decrease in the chance of women experiencing daytime falling asleep; however, this effect wasn’t mirrored in men. It’s crucial to note that we didn’t find significant associations between magnesium intake and daytime sleepiness or night snoring for either gender.
Overall, it seems that dietary magnesium might offer long-term benefits in reducing daytime sleepiness in women, while more research could clarify its effects on other symptoms. This makes magnesium an interesting dietary consideration for those seeking to improve their sleep quality.
References
Khalid S, Bashir S, Mehboob R, Anwar T, Ali M, et al. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus. Front Endocrinol (Lausanne). 2024;15:1370733. doi:10.3389/fendo.2024.1370733
Fathy W, Hussein M, Elanwar R, Elmoutaz H, Abdelsadek DA, et al. Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial. BMC Anesthesiol. 2024;24:289. doi:10.1186/s12871-024-02579-6
Rawji A, Peltier MR, Mourtzanakis K, Awan S, Rana J, et al. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review. Cureus. 2024;16:e59317. doi:10.7759/cureus.59317
Mah J, Pitre T. Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis. BMC Complement Med Ther. 2021;21:125. doi:10.1186/s12906-021-03297-z
Djokic G, Vojvodić P, Korcok D, Agic A, Rankovic A, et al. The Effects of Magnesium - Melatonin - Vit B Complex Supplementation in Treatment of Insomnia. Open Access Maced J Med Sci. 2019;7:3101. doi:10.3889/oamjms.2019.771
Cao Y, Zhen S, Taylor AW, Appleton S, Atlantis E, et al. Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up. Nutrients. 2018;10. doi:10.3390/nu10101354
Scholey A, Benson S, Gibbs A, Perry N, Sarris J, et al. Exploring the Effect of Lactium™ and Zizyphus Complex on Sleep Quality: A Double-Blind, Randomized Placebo-Controlled Trial. Nutrients. 2017;9. doi:10.3390/nu9020154
Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, et al. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17:1161.
Rondanelli M, Opizzi A, Monteferrario F, Antoniello N, Manni R, et al. The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial. J Am Geriatr Soc. 2011;59:82. doi:10.1111/j.1532-5415.2010.03232.x
Mucci M, Carraro C, Mancino P, Monti M, Papadia LS, et al. Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause. Minerva Ginecol. 2006;58:323.
Hornyak M, Haas P, Veit J, Gann H, Riemann D. Magnesium treatment of primary alcohol-dependent patients during subacute withdrawal: an open pilot study with polysomnography. Alcohol Clin Exp Res. 2004;28:1702.
Hornyak M, Voderholzer U, Hohagen F, Berger M, Riemann D. Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study. Sleep. 1998;21:501.