The Causal Role of Magnesium Deficiency in the Neuroinflammation, Pain Hypersensitivity and Memory/Emotional Deficits in Ovariectomized and Aged Female Mice.
We explored the connection between magnesium deficiency and various challenges commonly faced by postmenopausal women, such as chronic pain, memory decline, and mood disorders. Our research specifically focused on how magnesium supplementation can help in alleviating these issues in ovariectomized and aged female mice—modeling the postmenopausal state.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
Read More
7
Magnesium impacts menopause bone health
Magnesium Intake Predicts Bone Turnover in Postmenopausal Black South African Women.
We explored the relationship between magnesium intake and bone health in postmenopausal black South African women over a two-year period. In this study, which included 144 participants, researchers measured bone mineral density (BMD) at several key sites, alongside various biochemical analyses, including bone turnover markers.
The findings highlighted that higher dietary magnesium intake was linked to lower levels of C-Telopeptide of type I collagen (CTX-1), indicating reduced bone resorption. Moreover, calcium intake showed a positive correlation with BMD at the distal radius both at the start and end of the study.
Interestingly, one dietary pattern—snacking—also related to BMD scores over time, suggesting that what we eat can influence our bone health as we age. The results revealed that magnesium intake alone predicted a notable portion of the changes in bone turnover, emphasizing its potential role in supporting bone health during menopause.
Overall, this study suggests that paying attention to magnesium in our diets could be beneficial for women navigating menopause, especially regarding bone health.
Read More
7
Magnesium's limited effectiveness on menopause
The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a systematic review.
We reviewed various studies to understand how magnesium and other dietary supplements like B vitamins and essential fatty acids affect stress and anxiety in women. Our search included women aged 18 and older who had their stress levels assessed.
Although magnesium showed potential benefits, particularly in combination with vitamin B6 for premenstrual anxiety, the results overall suggested limited effectiveness in managing menopause-related anxiety when evaluated across all studies.
We found that essential fatty acids could help reduce stress during pregnancy and menopause, but more research is needed to establish more definitive findings.
Read More
Most Useful Reviews
9
Less irritable feeling.
2 people found this helpful
I recommend it! I purchased magnesium for its benefits on depression and irritability during menopause. After starting it, I felt less depressed and irritable, enabling me to live more comfortably. My mother had severe menopausal symptoms, but if taking magnesium can alleviate my fears about menopause, I’m delighted! I appreciate the capsule size as well, making it easy to take.
Read More
9
Mood improved significantly.
1 people found this helpful
I found it quite good! I’ve purchased this multiple times after reading about magnesium deficiency. My mood, previously a bit low, improved from the second day of intake, and irritability vanished. I initially thought this was just a symptom of menopause, yet it allowed me to live peacefully. I plan to reorder when it runs out.
Read More
9
Better sleep reported.
1 people found this helpful
Great product and price! The coated tablets are easy to swallow, which is important during menopause. They help with muscle tightness. I began with one to see if it assisted my sleep, and now I take up to three on occasion. Since I stopped using sleeping pills and melatonin, sleep improves significantly after taking these.
The Causal Role of Magnesium Deficiency in the Neuroinflammation, Pain Hypersensitivity and Memory/Emotional Deficits in Ovariectomized and Aged Female Mice.
We explored the connection between magnesium deficiency and various challenges commonly faced by postmenopausal women, such as chronic pain, memory decline, and mood disorders. Our research specifically focused on how magnesium supplementation can help in alleviating these issues in ovariectomized and aged female mice—modeling the postmenopausal state.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
Read More
9
Magnesium's impact on bone health
Supplementation of nanofiltrated deep ocean water ameliorate the progression of osteoporosis in ovariectomized rat via regulating osteoblast differentiation.
Our exploration centered on the effects of magnesium, particularly from nanofiltrated deep ocean water (DOW), in addressing osteoporosis, a common concern during menopause. In our study, we used ovariectomized female Sprague-Dawley rats, a model that simulates menopausal conditions. We administered varying amounts of DOW daily over eight weeks to observe its impact on bone health.
We found that DOW supplementation significantly increased bone density and reduced bone loss related to menopause. This was particularly notable as the rats that received DOW showed improved bone structure and reduced adiposity in their bones. More specifically, the lowest doses of DOW led to increased expression of a key protein called RUNX2, which plays an essential role in the formation of bone cells known as osteoblasts.
In human osteoblasts, DOW also raised levels of osteocalcin and alkaline phosphatase—both vital for promoting bone health. Overall, our findings demonstrated that magnesium-rich DOW can enhance osteoblast differentiation, contributing positively to bone structure integrity during menopause. This work highlights how incorporating magnesium into our diets or supplements could be beneficial for bone health as we age.
Read More
9
Isoflavones, probiotics boost bone health
Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial.
We explored the impact of a novel red clover extract rich in isoflavones and probiotics on bone health in postmenopausal osteopenic women. In a year-long double-blind trial with 78 participants, we compared this treatment alongside standard supplements against a placebo. Results showed that the extract substantially reduced bone mineral density loss and improved certain estrogen metabolism markers. However, it did not affect other bone turnover indicators significantly. Overall, combining the extract with calcium and magnesium proved beneficial for bone health in this demographic.
Read More
9
Magnesium reduces menopause symptoms
Effects of a new combination of nutraceuticals on postmenopausal symptoms and metabolic profile: a crossover, randomized, double-blind trial.
We explored the effects of a nutraceutical blend, including magnesium, on menopause symptoms through a crossover trial involving 43 postmenopausal women.
Participants experienced significant reductions in menopause symptoms, as measured by the Menopause Rating Scale, after using the nutraceuticals.
Additionally, improvements were noted in cardiovascular risk factors, such as lower cholesterol levels and blood pressure.
Overall, this study suggests that magnesium, combined with other nutrients, may provide meaningful relief for postmenopausal symptoms.
Read More
7
Magnesium aids menopausal metabolism
Utilizing a Combination of Supplements Comprising Boric Acid, Magnesium, Vitamin D3, and Extra Virgin Olive Oil to Improve Metabolism in Menopausal Ovariectomized Rats.
We conducted a study to understand how magnesium, along with other supplements, could influence metabolic health during menopause. Our research involved 42 adult female rats that were either ovariectomized or kept as controls. We divided them into seven groups to assess the effects of various treatments, including magnesium, boric acid, vitamin D3, extra virgin olive oil, and combinations of these supplements.
The results were promising. We observed significant improvements in markers related to inflammation, oxidative stress, and various metabolic parameters when magnesium was included in the treatment plans. Interestingly, the rats receiving magnesium, especially as part of a combined treatment, showed better results than those given individual supplements. This suggests that magnesium could play a valuable role in supporting metabolic health during menopause.
However, it’s worth noting that while magnesium demonstrated beneficial effects, the comprehensive impact of each supplement used individually wasn’t singled out for analysis. Thus, while magnesium appears to contribute positively, we cannot decisively state its specific role in isolation. Overall, our findings hint at a promising therapeutic potential for magnesium in managing menopausal symptoms, particularly when used alongside other beneficial nutrients.
I recommend it! I purchased magnesium for its benefits on depression and irritability during menopause. After starting it, I felt less depressed and irritable, enabling me to live more comfortably. My mother had severe menopausal symptoms, but if taking magnesium can alleviate my fears about menopause, I’m delighted! I appreciate the capsule size as well, making it easy to take.
Read More
9
Mood improved significantly.
1 people found this helpful
I found it quite good! I’ve purchased this multiple times after reading about magnesium deficiency. My mood, previously a bit low, improved from the second day of intake, and irritability vanished. I initially thought this was just a symptom of menopause, yet it allowed me to live peacefully. I plan to reorder when it runs out.
Read More
9
Better sleep reported.
1 people found this helpful
Great product and price! The coated tablets are easy to swallow, which is important during menopause. They help with muscle tightness. I began with one to see if it assisted my sleep, and now I take up to three on occasion. Since I stopped using sleeping pills and melatonin, sleep improves significantly after taking these.
Read More
7.5
Symptoms alleviated overall.
The drug was recommended by my doctor. The benefits of magnesium citrate include providing energy to cells and commencing necessary biochemical processes. It effectively addresses sleep disorders and digestive issues while relieving menstruation and menopause symptoms. Overall, my health has improved, leading to calmness and better sleep.
Read More
7
Notable improvement
Good magnesium. I've ordered it before and take two capsules at night. Now, during menopause, I can feel the noticeable effects of the supplement.
Menopause is a natural biological process that marks the end of a woman's reproductive years, characterized by the cessation of menstruation and a decline in hormonal levels, particularly estrogen and progesterone. Typically occurring between the ages of 45 and 55, menopause can bring a variety of physical and emotional changes. Common symptoms may include hot flashes, night sweats, mood swings, and changes in sleep patterns. It is important to note that menopause is a gradual process and often begins with perimenopause, where women may experience irregular periods and increased symptoms for several years before periods stop completely.
While menopause is a natural phase of life, it can have significant impacts on a woman's health and well-being. This transition can increase the risk of certain health issues, such as osteoporosis and cardiovascular disease, due in part to lowered hormone levels. Therefore, it is advisable for women to consult with healthcare providers to discuss potential management strategies and lifestyle adjustments during this time. These may include hormone replacement therapy, dietary changes, regular physical activity, and alternative therapies, all aimed at alleviating symptoms and promoting overall health during and after menopause.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium is often highlighted for its potential benefits during menopause, although the evidence is not as comprehensive as one might hope. Some studies suggest that magnesium may help alleviate certain symptoms associated with menopause, such as mood swings, anxiety, and sleep disturbances. This mineral plays a crucial role in various bodily functions, including hormone regulation and stress response, which means that adequate magnesium levels might contribute to a smoother transition during this life stage.
In addition to its potential symptom-relieving properties, magnesium is also known for its overall health benefits, including supporting bone health, which is particularly important during menopause as women are at a higher risk for osteoporosis. It is generally advisable to maintain a balanced diet rich in magnesium through foods like leafy greens, nuts, seeds, and whole grains. However, it's always wise to consult with a healthcare provider before starting any supplementation, especially during menopause, to ensure it's safe and appropriate for your individual health needs.
Based on user reviews, the time frame for noticing results from taking magnesium supplements for menopause can vary. Many users report experiencing improvements quite rapidly; for instance, one user mentioned feeling a boost in mood and a decrease in irritability starting from just the second day of intake Read Review. Another user highlighted a significant reduction in symptoms, contributing to a more comfortable experience of menopause in a relatively short period Read Review.
However, results may differ based on individual circumstances. While some users have noticed benefits early on, such as improved sleep and reduced muscle tightness, others may take longer to experience noticeable changes Read ReviewRead Review. Overall, you might expect to feel some positive effects within a few days to a week after starting supplementation.
Magnesium supplementation appears to be supported by scientific research for managing various aspects of menopause. Studies suggest that magnesium can positively influence metabolic health during this transition, as indicated by improvements in inflammation and oxidative stress markers in ovariectomized rats [1]. Additionally, research involving mice has shown that magnesium supplementation can alleviate common menopause-related challenges, such as chronic pain, memory decline, and mood disorders, highlighting its therapeutic potential for postmenopausal health [2].
Moreover, evidence suggests that magnesium can play a crucial role in supporting bone health during menopause. One study indicated that magnesium-rich deep ocean water significantly increased bone density and improved bone structure in a rat model simulating menopause [3]. Another study found a relationship between dietary magnesium intake and lower bone resorption levels in postmenopausal women [5]. Although the effectiveness of magnesium for managing menopause-related anxiety might be limited [7], research indicates that a combination of magnesium with other nutrients can provide substantial relief from menopause symptoms and other health concerns [8]. Thus, incorporating magnesium into a menopausal health regimen could be beneficial.
Users have reported a wide range of improvements in their symptoms after taking magnesium supplements, especially related to menopause. Many users noted significant enhancements in mood and reductions in irritability shortly after starting the supplement. For instance, one user felt a considerable lift in mood and a vanishing irritability level by just the second day of intake Read Review. Another user emphasized how magnesium allowed them to navigate menopause more comfortably, reflecting a positive impact on their overall mental well-being Read Review.
In addition to mood improvements, users often mentioned benefits like better sleep quality and relief from muscle tightness, contributing to a more restful experience at night Read Review. Some users even reported improvements in digestion and energy levels, leading to an overall sense of calm and better health Read Review. While many experienced these positive outcomes, it’s important to remember that individual results can vary based on personal health circumstances and supplements’ effectiveness Read Review.
Users report positive experiences when combining magnesium supplements with other treatments for menopause, noting its potential effectiveness in alleviating various symptoms. Many users have indicated that magnesium helped improve their mood and reduced irritability, providing a more comfortable experience during this transition period. For instance, one user emphasized their noticeable improvement in mood just days after starting the supplement, which contributed significantly to their well-being during menopause Read Review. Others highlighted the benefits of magnesium in promoting better sleep and relaxation, which can be particularly advantageous when paired with other wellness strategies aimed at managing menopausal symptoms Read Review.
Moreover, users sharing their experiences with pre-menopausal symptoms also reported that magnesium has been beneficial, stating improvements in frustration levels and relief from various symptoms Read Review. The versatility of magnesium in addressing mood disorders, sleep issues, and physical discomfort has led several users to recommend it as a supportive supplement alongside other treatments for menopause Read Review. However, users also noted that moderation is essential, as excessive intake can lead to gastrointestinal discomfort Read Review.
Based on user reviews, there seems to be a range of effective dosages for magnesium when it comes to alleviating menopausal symptoms. Some users reported taking one capsule initially to assess its effects, but later increased their intake to up to three capsules as needed, particularly to improve sleep and alleviate irritability (Read Review). Another user mentioned taking two capsules at night specifically during menopause and noted that they could feel a noticeable impact from the supplement (Read Review).
Moreover, users have highlighted the importance of individualized dosage, suggesting that starting with a lower dose to monitor effects might be wise. One user commented on experiencing decreased frustration during the luteal phase while taking magnesium, indicating positive outcomes with their dosage, albeit they advised caution about taking too much (Read Review). Overall, the consensus appears to be that magnesium can be a beneficial supplement during menopause, with users finding varying success at different dosage levels.
9
Mood improved significantly.
1 people found this helpful
I found it quite good! I’ve purchased this multiple times after reading about magnesium deficiency. My mood, previously a bit low, improved from the second day of intake, and irritability vanished. I initially thought this was just a symptom of menopause, yet it allowed me to live peacefully. I plan to reorder when it runs out.
9
Less irritable feeling.
2 people found this helpful
I recommend it! I purchased magnesium for its benefits on depression and irritability during menopause. After starting it, I felt less depressed and irritable, enabling me to live more comfortably. My mother had severe menopausal symptoms, but if taking magnesium can alleviate my fears about menopause, I’m delighted! I appreciate the capsule size as well, making it easy to take.
9
Better sleep reported.
1 people found this helpful
Great product and price! The coated tablets are easy to swallow, which is important during menopause. They help with muscle tightness. I began with one to see if it assisted my sleep, and now I take up to three on occasion. Since I stopped using sleeping pills and melatonin, sleep improves significantly after taking these.
7.5
Symptoms alleviated overall.
The drug was recommended by my doctor. The benefits of magnesium citrate include providing energy to cells and commencing necessary biochemical processes. It effectively addresses sleep disorders and digestive issues while relieving menstruation and menopause symptoms. Overall, my health has improved, leading to calmness and better sleep.
7
Notable improvement
Good magnesium. I've ordered it before and take two capsules at night. Now, during menopause, I can feel the noticeable effects of the supplement.
7.5
Reduced frustration observed.
3 people found this helpful
I am taking magnesium because I am in the pre-menopause period. My frustration during the luteal phase has significantly decreased. It even helps me feel better after consuming sweets, which I find very helpful. However, be aware that taking too much can cause loose stools.
7
Magnesium aids menopausal metabolism
Utilizing a Combination of Supplements Comprising Boric Acid, Magnesium, Vitamin D3, and Extra Virgin Olive Oil to Improve Metabolism in Menopausal Ovariectomized Rats.
We conducted a study to understand how magnesium, along with other supplements, could influence metabolic health during menopause. Our research involved 42 adult female rats that were either ovariectomized or kept as controls. We divided them into seven groups to assess the effects of various treatments, including magnesium, boric acid, vitamin D3, extra virgin olive oil, and combinations of these supplements.
The results were promising. We observed significant improvements in markers related to inflammation, oxidative stress, and various metabolic parameters when magnesium was included in the treatment plans. Interestingly, the rats receiving magnesium, especially as part of a combined treatment, showed better results than those given individual supplements. This suggests that magnesium could play a valuable role in supporting metabolic health during menopause.
However, it’s worth noting that while magnesium demonstrated beneficial effects, the comprehensive impact of each supplement used individually wasn’t singled out for analysis. Thus, while magnesium appears to contribute positively, we cannot decisively state its specific role in isolation. Overall, our findings hint at a promising therapeutic potential for magnesium in managing menopausal symptoms, particularly when used alongside other beneficial nutrients.
9
Magnesium aids menopause-related issues
The Causal Role of Magnesium Deficiency in the Neuroinflammation, Pain Hypersensitivity and Memory/Emotional Deficits in Ovariectomized and Aged Female Mice.
We explored the connection between magnesium deficiency and various challenges commonly faced by postmenopausal women, such as chronic pain, memory decline, and mood disorders. Our research specifically focused on how magnesium supplementation can help in alleviating these issues in ovariectomized and aged female mice—modeling the postmenopausal state.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
9
Magnesium's impact on bone health
Supplementation of nanofiltrated deep ocean water ameliorate the progression of osteoporosis in ovariectomized rat via regulating osteoblast differentiation.
Our exploration centered on the effects of magnesium, particularly from nanofiltrated deep ocean water (DOW), in addressing osteoporosis, a common concern during menopause. In our study, we used ovariectomized female Sprague-Dawley rats, a model that simulates menopausal conditions. We administered varying amounts of DOW daily over eight weeks to observe its impact on bone health.
We found that DOW supplementation significantly increased bone density and reduced bone loss related to menopause. This was particularly notable as the rats that received DOW showed improved bone structure and reduced adiposity in their bones. More specifically, the lowest doses of DOW led to increased expression of a key protein called RUNX2, which plays an essential role in the formation of bone cells known as osteoblasts.
In human osteoblasts, DOW also raised levels of osteocalcin and alkaline phosphatase—both vital for promoting bone health. Overall, our findings demonstrated that magnesium-rich DOW can enhance osteoblast differentiation, contributing positively to bone structure integrity during menopause. This work highlights how incorporating magnesium into our diets or supplements could be beneficial for bone health as we age.
7
Magnesium impacts menopause bone health
Magnesium Intake Predicts Bone Turnover in Postmenopausal Black South African Women.
We explored the relationship between magnesium intake and bone health in postmenopausal black South African women over a two-year period. In this study, which included 144 participants, researchers measured bone mineral density (BMD) at several key sites, alongside various biochemical analyses, including bone turnover markers.
The findings highlighted that higher dietary magnesium intake was linked to lower levels of C-Telopeptide of type I collagen (CTX-1), indicating reduced bone resorption. Moreover, calcium intake showed a positive correlation with BMD at the distal radius both at the start and end of the study.
Interestingly, one dietary pattern—snacking—also related to BMD scores over time, suggesting that what we eat can influence our bone health as we age. The results revealed that magnesium intake alone predicted a notable portion of the changes in bone turnover, emphasizing its potential role in supporting bone health during menopause.
Overall, this study suggests that paying attention to magnesium in our diets could be beneficial for women navigating menopause, especially regarding bone health.
7
Magnesium's limited effectiveness on menopause
The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a systematic review.
We reviewed various studies to understand how magnesium and other dietary supplements like B vitamins and essential fatty acids affect stress and anxiety in women. Our search included women aged 18 and older who had their stress levels assessed.
Although magnesium showed potential benefits, particularly in combination with vitamin B6 for premenstrual anxiety, the results overall suggested limited effectiveness in managing menopause-related anxiety when evaluated across all studies.
We found that essential fatty acids could help reduce stress during pregnancy and menopause, but more research is needed to establish more definitive findings.
9
Magnesium reduces menopause symptoms
Effects of a new combination of nutraceuticals on postmenopausal symptoms and metabolic profile: a crossover, randomized, double-blind trial.
We explored the effects of a nutraceutical blend, including magnesium, on menopause symptoms through a crossover trial involving 43 postmenopausal women.
Participants experienced significant reductions in menopause symptoms, as measured by the Menopause Rating Scale, after using the nutraceuticals.
Additionally, improvements were noted in cardiovascular risk factors, such as lower cholesterol levels and blood pressure.
Overall, this study suggests that magnesium, combined with other nutrients, may provide meaningful relief for postmenopausal symptoms.
References
Atteia HH, Ahmed SF, Askar ME, Sakr AT. Utilizing a Combination of Supplements Comprising Boric Acid, Magnesium, Vitamin D3, and Extra Virgin Olive Oil to Improve Metabolism in Menopausal Ovariectomized Rats. Biol Trace Elem Res. 2024. doi:10.1007/s12011-024-04476-y
Zhang J, Mai CL, Xiong Y, Lin ZJ, Jie YT, et al. The Causal Role of Magnesium Deficiency in the Neuroinflammation, Pain Hypersensitivity and Memory/Emotional Deficits in Ovariectomized and Aged Female Mice. J Inflamm Res. 2021;14:6633. doi:10.2147/JIR.S330894
Chen PC, Lee YC, Jao HY, Wang CP, Jacobs A, et al. Supplementation of nanofiltrated deep ocean water ameliorate the progression of osteoporosis in ovariectomized rat via regulating osteoblast differentiation. J Food Biochem. 2020;44:e13236. doi:10.1111/jfbc.13236
Kolanu BR, Vadakedath S, Boddula V, Kandi V. Activities of Serum Magnesium and Thyroid Hormones in Pre-, Peri-, and Post-menopausal Women. Cureus. 2020;12:e6554. doi:10.7759/cureus.6554
Wright HH, Kruger MC, Schutte WD, Wentzel-Viljoen E, Kruger IM, et al. Magnesium Intake Predicts Bone Turnover in Postmenopausal Black South African Women. Nutrients. 2019;11. doi:10.3390/nu11102519
Lambert MNT, Thybo CB, Lykkeboe S, Rasmussen LM, Frette X, et al. Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial. Am J Clin Nutr. 2017;106:909. doi:10.3945/ajcn.117.153353
McCabe D, Lisy K, Lockwood C, Colbeck M. The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a systematic review. JBI Database System Rev Implement Rep. 2017;15:402. doi:10.11124/JBISRIR-2016-002965
Trimarco V, Rozza F, Izzo R, De Leo V, Cappelli V, et al. Effects of a new combination of nutraceuticals on postmenopausal symptoms and metabolic profile: a crossover, randomized, double-blind trial. Int J Womens Health. 2016;8:581.