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The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
Our findings showed a significant reduction in reflux symptoms across all infant groups. However, there was no significant difference in effectiveness between the two treatments. Importantly, using magnesium alginate also yielded cost savings of about €4.60 per infant compared to the thickened formula.
Thus, magnesium alginate appears to be a cost-effective option without sacrificing symptom relief.
One hundred patients participated in this study, all treated with Gaviscon® Advance and monitored over three months.
The findings indicated that while Gaviscon® Advance is effective on its own, combining it with a high-dose PPI did not enhance symptom relief.
This suggests that Gaviscon® Advance can be a sufficient treatment for LPR without needing the added PPI.
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The results showed a clear advantage for Gaviscon DA, with pH levels reaching 4 or higher nearly 47% of the time, compared to just 5% for the placebo. This confirms that Gaviscon DA effectively neutralizes gastric acid, enhancing the understanding of how its components work together for reflux relief.
Results showed that the decoction significantly improved throat burning, swallowing difficulties, and hiccups more effectively than Western treatments. However, the Western medicine group had better relief for heartburn and gastric burning sensations.
Factors like age and gastroesophageal flap valve grade also impacted treatment effectiveness.
The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
The experimental group received a combination of Lanqin oral solution and Weisu granules, while the control groups used either Lanqin alone or Esomeprazole with Lanqin.
After four weeks, the experimental group showed a remarkable 91.7% improvement, much higher than the 73.3% in control group A. Although the experimental group differed significantly from control group A, results were similar to control group B, indicating no major advantage over Esomeprazole.
Our findings suggest that those taking GutGard® experienced quicker relief from symptoms like heartburn and regurgitation, showing improvements within just two weeks. This indicates that GutGard® could be an effective option for managing GER symptoms.
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Frequently Asked Questions
Reflux, medically known as gastroesophageal reflux disease (GERD), occurs when stomach acid flows back into the esophagus, the tube that connects the throat to the stomach. This backflow can lead to symptoms such as heartburn, regurgitation, and difficulty swallowing. Reflux can affect people of all ages and may be triggered or worsened by factors such as diet, obesity, smoking, and certain medications. While occasional reflux is common and often manageable with lifestyle changes, chronic reflux can lead to more serious complications if not properly treated.
Managing reflux typically involves a combination of lifestyle modifications—such as avoiding trigger foods, eating smaller meals, and maintaining a healthy weight—and, in some cases, medication to reduce stomach acid production. In more severe cases, surgical options may be considered. If you suspect you have reflux or experience frequent symptoms, it’s advisable to consult a healthcare professional for an accurate diagnosis and personalized treatment plan.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium is often touted for its various health benefits, including its ability to assist with digestive issues, but its role in alleviating reflux symptoms is somewhat limited and not well-established. Some studies suggest that magnesium can help relax the muscles in the digestive tract and may help improve overall digestion, which could indirectly benefit those experiencing reflux. Additionally, magnesium plays a crucial role in regulating stomach acid production, and some individuals find that increasing magnesium intake can lead to improved gastrointestinal health.
However, it’s essential to note that while magnesium can be a supportive element in your overall health regime, it should not be considered a primary treatment for gastroesophageal reflux disease (GERD). If you experience chronic reflux, it is advisable to consult with a healthcare professional for a comprehensive treatment strategy that may include dietary changes, lifestyle modifications, or medication. Some foods rich in magnesium, like leafy greens, nuts, and whole grains, can be beneficial as part of a balanced diet, but they are not a substitute for targeted reflux management.
Based on user reviews, the time it takes to see results from this supplement for reflux can vary. Some users noted experiencing relief relatively quickly, with positive effects reported within just a few days. For example, one user mentioned feeling a significant difference after only ten days of use, highlighting improvements in nervous tension and overall comfort (Read Review). Similarly, another individual observed marked reduction in acid reflux and bloating after initiating the supplement with each meal (Read Review).
Overall, while individual responses may differ, many users suggest that noticeable improvements can typically be felt within the first couple of weeks of consistent use. Several reviews indicate an enhancement in symptoms such as discomfort and pain relief related to reflux shortly after starting the supplement (Read Review)(Read Review). Therefore, patience and regularity in taking the supplement appear key for optimal results.
This supplement, particularly GutGard®, has shown promising results in scientific studies related to gastroesophageal reflux (GER). In a clinical trial involving participants assigned to either GutGard® or a placebo, those taking the supplement reported quicker relief from symptoms like heartburn and regurgitation, demonstrating significant improvements within just two weeks [1]. These findings suggest that GutGard® could be a viable option for managing GER symptoms effectively.
Other supplements, such as magnesium alginate, have also shown efficacy in treating reflux symptoms. Research indicated that magnesium alginate was effective for laryngopharyngeal reflux, reducing symptoms substantially in a controlled study [4]. Additionally, Gaviscon Advance was found to significantly suppress acid reflux in specific populations, making it a strong candidate for reflux symptom management [5]. Overall, various supplements appear to be supported by scientific data, hinting that they could be beneficial for those suffering from reflux-related issues.
Based on user reviews, many individuals have reported significant improvements in symptoms after incorporating this supplement into their routines. For instance, one user noted that their gastrointestinal issues improved markedly, with reflux gastritis no longer causing discomfort, and they even experienced a reduction in nervousness related to PMS (Read Review). Another user highlighted a noticeable decrease in discomfort and pain associated with reflux, contributing to an overall enhanced sense of well-being (Read Review).
Several reviews underscored the effectiveness of the supplement for relieving reflux specifically, with one user expressing that they experienced no reflux or negative aftertaste after beginning the regimen (Read Review). Additionally, it helped alleviate esophageal pain and promoted relaxation, ultimately supporting deeper sleep and easing muscle tightness (Read Review). Overall, while results can vary from person to person, many users reported feeling relief and other positive changes within just a short period of consistent use.
Based on user reviews, many individuals have reported positive experiences when combining this supplement with other dietary practices. Several users specifically mentioned that taking the capsules with meals enhanced their overall effectiveness in managing reflux symptoms. For instance, one user noted a significant decrease in acid reflux when taking the supplement alongside their regular meals, highlighting improvements in both gastrointestinal comfort and regularity (Read Review). Another user emphasized that this supplement, taken as directed, alleviated gastrointestinal issues, including reflux gastritis (Read Review).
Moreover, the reviews suggest that users often couple this supplement with a mindful approach to their eating habits, which includes timing their doses appropriately for optimal results. One reviewer remarked on the ease of taking the capsules without experiencing any adverse effects, such as reflux or aftertaste, indicating that they felt more comfortable integrating the supplement into their routine (Read Review). Overall, while individual responses may vary, many users found that combining the supplement with meals contributed to a greater sense of well-being and reduced discomfort associated with reflux, forming part of a broader strategy to manage symptoms effectively.
Based on user reviews, it seems that the right dosage for Magnesium to assist with reflux symptoms can vary, but several users have reported consistent benefits from specific dosing regimens. One user mentioned taking three capsules before bedtime as directed by their doctor, which resulted in improved gastrointestinal health and cessation of reflux-related issues (Read Review). Another user indicated they take their magnesium capsules with each meal and have experienced a noticeable reduction in acid reflux, along with increased regularity and less bloating (Read Review).
Overall, individuals reported positive outcomes from different dosing strategies, and finding the right amount may be a personal journey based on the severity of symptoms and individual tolerance. Importantly, users consistently noted improvements in their reflux symptoms and related discomfort, suggesting that magnesium can be an effective supplement for many (Read Review).
Our findings suggest that those taking GutGard® experienced quicker relief from symptoms like heartburn and regurgitation, showing improvements within just two weeks. This indicates that GutGard® could be an effective option for managing GER symptoms.
The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
Findings showed that Gaviscon Advance significantly suppressed the acid pocket and reduced symptoms like regurgitation better than the non-alginate antacid. This suggests that Gaviscon Advance may be a better treatment option for obesity-related reflux following late-night eating.
References
- Raj JP, Saxena U, Belhekar MN, Mamde A, Darak H, et al. Efficacy and Safety of GutGard® in Managing Gastroesophageal Reflux-Related Symptoms: A Phase III, Single-Centre, Double-Blind, Randomized Placebo-Controlled Trial. Complement Med Res. 2025;32:26. doi:10.1159/000543367
- Song S, Zhang Y, Zhang J, Jiang Y, Gong A. Efficacy evaluation and exploratory analysis of influencing factors of Banxia Houpu Decoction in the treatment of refractory gastroesophageal reflux disease. Medicine (Baltimore). 2024;103:e38045. doi:10.1097/MD.0000000000038045
- Pizzorni N, Ambrogi F, Eplite A, Rama S, Robotti C, et al. Magnesium alginate versus proton pump inhibitors for the treatment of laryngopharyngeal reflux: a non-inferiority randomized controlled trial. Eur Arch Otorhinolaryngol. 2022;279:2533. doi:10.1007/s00405-021-07219-0
- Ciprandi G, Damiani V, Passali FM, Crisanti A, Motta G, et al. Magnesium alginate in patients with laryngopharyngeal reflux. J Biol Regul Homeost Agents. 2021;35:61. doi:10.23812/21-1supp2-12
- Deraman MA, Abdul Hafidz MI, Lawenko RM, Ma ZF, Wong MS, et al. Randomised clinical trial: the effectiveness of Gaviscon Advance vs non-alginate antacid in suppression of acid pocket and post-prandial reflux in obese individuals after late-night supper. Aliment Pharmacol Ther. 2020;51:1014. doi:10.1111/apt.15746
- Dragomiretska NV, Babov KD, Gushcha SG, Zabolotna IB, Plakida AL, et al. Application of mineral waters in the complex treatment of patients with gastroesophageal reflux disease. Minerva Gastroenterol Dietol. 2020;66:225. doi:10.23736/S1121-421X.20.02601-X
- Baldassarre ME, Di Mauro A, Pignatelli MC, Fanelli M, Salvatore S, et al. Magnesium Alginate in Gastro-Esophageal Reflux: A Randomized Multicenter Cross-Over Study in Infants. Int J Environ Res Public Health. 2019;17. doi:10.3390/ijerph17010083
- Wilkinson J, Abd-Elaziz K, den Daas I, Wemer J, van Haastert M, et al. Two placebo-controlled crossover studies in healthy subjects to evaluate gastric acid neutralization by an alginate-antacid formulation (Gaviscon Double Action). Drug Dev Ind Pharm. 2019;45:430. doi:10.1080/03639045.2018.1546314
- Wilkie MD, Fraser HM, Raja H. Gaviscon® Advance alone versus co-prescription of Gaviscon® Advance and proton pump inhibitors in the treatment of laryngopharyngeal reflux. Eur Arch Otorhinolaryngol. 2018;275:2515. doi:10.1007/s00405-018-5079-0
- Zhuang XY, Yang HZ, Wang HG, Li CW. [Clinical observation of Weisu granules in treating laryngopharyngeal reflux]. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018;32:369. doi:10.13201/j.issn.1001-1781.2018.05.012
- Bianchetti M, Peralta S, Nicita R, Aragona SE, Ciprandi G. Emerging from gastroesophageal reflux (EMERGE): An Italian survey - II the viewpoint of the patient. J Biol Regul Homeost Agents. 2018;32:983.
