Last update
3/30/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 1 Lozenge
Amount Per Serving
%DV
Vitamin B-12 (as Methylcobalamin)
1 mg (1,000 mcg)
41,667%
Top Medical Research Studies
9
Vitamin B12 may aid menopause relief
We observed the effects of a nutritional product that combined various ingredients, including vitamin B12, on menopausal symptoms. This study involved 156 menopausal women who took the product daily for 12 weeks and reported their symptoms using a validated scale.
After completing the study, we found significant reductions in various menopause-related issues. This included a substantial 45% decrease in depressive mood and a notable reduction of 48% in hot flashes. It's important to note that while vitamin B12 was included in the treatment, it was part of a broader combination with other beneficial ingredients.
However, we must clarify that the specific impact of vitamin B12 alone cannot be fully determined from this study. The results are promising for the product as a whole, showing effective relief from many menopausal symptoms, but further research is needed to isolate the role of vitamin B12 in managing these symptoms.
After completing the study, we found significant reductions in various menopause-related issues. This included a substantial 45% decrease in depressive mood and a notable reduction of 48% in hot flashes. It's important to note that while vitamin B12 was included in the treatment, it was part of a broader combination with other beneficial ingredients.
However, we must clarify that the specific impact of vitamin B12 alone cannot be fully determined from this study. The results are promising for the product as a whole, showing effective relief from many menopausal symptoms, but further research is needed to isolate the role of vitamin B12 in managing these symptoms.
Read More
9
vitamin B12 aids menopause dry eye
We explored the impact of vitamin B12, alongside hyaluronic acid and electrolytes, on menopausal women suffering from moderate dry eye disease. In this study, thirty female participants, aged between 45 to 65, received drops that contained 0.3% sodium hyaluronate, vitamin B12, and other electrolytes for a duration of 30 days.
Throughout this period, we tracked their symptoms and performed several tests to gauge the severity of dry eye, including the Ocular Surface Disease Index (OSDI) questionnaire and tear film assessments. Our findings indicated that the combination of these treatments significantly decreased the symptoms of dry eye disease. Specifically, we noted a substantial improvement in the scores from the OSDI questionnaire and enhancements in both the tear volume and stability.
The results suggest that vitamin B12 plays a supportive role in alleviating dry eye symptoms during menopause, contributing positively when used with other treatments. While it’s hard to isolate the specific benefits of vitamin B12 due to the combination used, its inclusion in the eye drops appears to aid in improving overall eye health for menopausal women dealing with dryness.
Throughout this period, we tracked their symptoms and performed several tests to gauge the severity of dry eye, including the Ocular Surface Disease Index (OSDI) questionnaire and tear film assessments. Our findings indicated that the combination of these treatments significantly decreased the symptoms of dry eye disease. Specifically, we noted a substantial improvement in the scores from the OSDI questionnaire and enhancements in both the tear volume and stability.
The results suggest that vitamin B12 plays a supportive role in alleviating dry eye symptoms during menopause, contributing positively when used with other treatments. While it’s hard to isolate the specific benefits of vitamin B12 due to the combination used, its inclusion in the eye drops appears to aid in improving overall eye health for menopausal women dealing with dryness.
Read More
Most Useful Reviews
9
Pain relief achieved
10 people found this helpful
Due to menopause, I had numbness in my fingers, particularly in my index finger and thumb, which was quite painful. After researching, I discovered that B12 could be beneficial, but I struggled to find a standalone supplement in Japan, so I purchased it here. After starting the supplement, the pain disappeared, allowing me to open plastic bottle lids again. During severe episodes, I took it thrice daily after meals. I realised I was quite B12 deficient, so I bought more and keep it refrigerated as it melts easily.
Read More
7.5
Improved hand function
4 people found this helpful
To combat stiffness and numbness in my hands caused by menopause, I learned that Vitamin B12 could aid nerve recovery, so I decided to try it. While my hands are still somewhat numb, I've noticed an improvement in stiffness, for which I am truly grateful. I now maintain a positive mindset and strive to support my health through nutritious food, supplements, and exercise during this menopausal phase.
Read More
6
Eased discomfort
Taking these for menopause, I've experienced significant hip pain, headaches, and other issues since entering this phase. I’ve read that B12 can help alleviate these symptoms. Although I haven’t been using them for long, I've noticed some relief already. I hope that with continued use, I will benefit even more.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
- All Researches
9
Vitamin B12 may aid menopause relief
We observed the effects of a nutritional product that combined various ingredients, including vitamin B12, on menopausal symptoms. This study involved 156 menopausal women who took the product daily for 12 weeks and reported their symptoms using a validated scale.
After completing the study, we found significant reductions in various menopause-related issues. This included a substantial 45% decrease in depressive mood and a notable reduction of 48% in hot flashes. It's important to note that while vitamin B12 was included in the treatment, it was part of a broader combination with other beneficial ingredients.
However, we must clarify that the specific impact of vitamin B12 alone cannot be fully determined from this study. The results are promising for the product as a whole, showing effective relief from many menopausal symptoms, but further research is needed to isolate the role of vitamin B12 in managing these symptoms.
After completing the study, we found significant reductions in various menopause-related issues. This included a substantial 45% decrease in depressive mood and a notable reduction of 48% in hot flashes. It's important to note that while vitamin B12 was included in the treatment, it was part of a broader combination with other beneficial ingredients.
However, we must clarify that the specific impact of vitamin B12 alone cannot be fully determined from this study. The results are promising for the product as a whole, showing effective relief from many menopausal symptoms, but further research is needed to isolate the role of vitamin B12 in managing these symptoms.
Read More
9
vitamin B12 aids menopause dry eye
We explored the impact of vitamin B12, alongside hyaluronic acid and electrolytes, on menopausal women suffering from moderate dry eye disease. In this study, thirty female participants, aged between 45 to 65, received drops that contained 0.3% sodium hyaluronate, vitamin B12, and other electrolytes for a duration of 30 days.
Throughout this period, we tracked their symptoms and performed several tests to gauge the severity of dry eye, including the Ocular Surface Disease Index (OSDI) questionnaire and tear film assessments. Our findings indicated that the combination of these treatments significantly decreased the symptoms of dry eye disease. Specifically, we noted a substantial improvement in the scores from the OSDI questionnaire and enhancements in both the tear volume and stability.
The results suggest that vitamin B12 plays a supportive role in alleviating dry eye symptoms during menopause, contributing positively when used with other treatments. While it’s hard to isolate the specific benefits of vitamin B12 due to the combination used, its inclusion in the eye drops appears to aid in improving overall eye health for menopausal women dealing with dryness.
Throughout this period, we tracked their symptoms and performed several tests to gauge the severity of dry eye, including the Ocular Surface Disease Index (OSDI) questionnaire and tear film assessments. Our findings indicated that the combination of these treatments significantly decreased the symptoms of dry eye disease. Specifically, we noted a substantial improvement in the scores from the OSDI questionnaire and enhancements in both the tear volume and stability.
The results suggest that vitamin B12 plays a supportive role in alleviating dry eye symptoms during menopause, contributing positively when used with other treatments. While it’s hard to isolate the specific benefits of vitamin B12 due to the combination used, its inclusion in the eye drops appears to aid in improving overall eye health for menopausal women dealing with dryness.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Pain relief achieved
10 people found this helpful
Due to menopause, I had numbness in my fingers, particularly in my index finger and thumb, which was quite painful. After researching, I discovered that B12 could be beneficial, but I struggled to find a standalone supplement in Japan, so I purchased it here. After starting the supplement, the pain disappeared, allowing me to open plastic bottle lids again. During severe episodes, I took it thrice daily after meals. I realised I was quite B12 deficient, so I bought more and keep it refrigerated as it melts easily.
Read More
7.5
Improved hand function
4 people found this helpful
To combat stiffness and numbness in my hands caused by menopause, I learned that Vitamin B12 could aid nerve recovery, so I decided to try it. While my hands are still somewhat numb, I've noticed an improvement in stiffness, for which I am truly grateful. I now maintain a positive mindset and strive to support my health through nutritious food, supplements, and exercise during this menopausal phase.
Read More
6
Eased discomfort
Taking these for menopause, I've experienced significant hip pain, headaches, and other issues since entering this phase. I’ve read that B12 can help alleviate these symptoms. Although I haven’t been using them for long, I've noticed some relief already. I hope that with continued use, I will benefit even more.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Palacios S, Mustata C, Rizo JM, Regidor PA. Improvement in menopausal symptoms with a nutritional product containing evening primrose oil, hop extract, saffron, tryptophan, vitamins B6, D3, K2, B12, and B9. Eur Rev Med Pharmacol Sci. 2023;27:8180. 10.26355/eurrev_202309_33578
- De-Hita-Cantalejo C, Sánchez-González MC, Silva-Viguera C, GarcĂa-Romera MC, Feria-Mantero R, et al. Efficacy of hyaluronic acid 0.3%, cyanocobalamin, electrolytes, and P-Plus in menopause patients with moderate dry eye disease. Graefes Arch Clin Exp Ophthalmol. 2022;260:529. 10.1007/s00417-021-05415-6
Data last updated:
