' 
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.2
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 1/4 Level Teaspoon (1.1 g)
Amount Per Serving
%DV
Vitamin C (Ascorbic Acid)
1.1 g (1,100 mg)
1222%
Top Medical Research Studies
8
DDH-1 shows psoriasis improvement
Ascorbic acid derivative DDH-1 ameliorates psoriasis-like skin lesions in mice by suppressing inflammatory cytokine expression.
Directly related to vitamin C use.
We explored the potential of DDH-1, a unique derivative of ascorbic acid, in treating psoriasis, a chronic inflammatory skin condition driven by certain cytokines. In our research, mice with psoriasis-like skin lesions induced by imiquimod were treated with DDH-1 to examine its effects on inflammatory markers.
During our study, we found that treatment with DDH-1 significantly reduced the expression of inflammatory cytokines IL-1β and TNF-α in the affected skin. This finding is crucial, as these cytokines are key players in the development and persistence of psoriasis.
Additionally, we observed noticeable improvement in the skin lesions of the mice following the application of DDH-1. These promising results indicate that DDH-1 may be beneficial for those looking to manage psoriasis and could serve as a supplement in treatment strategies.
During our study, we found that treatment with DDH-1 significantly reduced the expression of inflammatory cytokines IL-1β and TNF-α in the affected skin. This finding is crucial, as these cytokines are key players in the development and persistence of psoriasis.
Additionally, we observed noticeable improvement in the skin lesions of the mice following the application of DDH-1. These promising results indicate that DDH-1 may be beneficial for those looking to manage psoriasis and could serve as a supplement in treatment strategies.
Read More
9
Pustular psoriasis treatment insights
ARDS complicating pustular psoriasis: treatment with low-dose corticosteroids, vitamin C and thiamine.
Combined treatments complicate results
We examined a case involving a 45-year-old woman with a history of psoriasis who developed serious respiratory distress attributed to a pustular flare of her skin condition. Admitted to the intensive care unit, she presented with acute symptoms, including a diffuse rash and difficulty breathing, alongside findings consistent with non-cardiogenic pulmonary edema.
In evaluating her treatment, we noted that vitamin C was part of a comprehensive regimen that also included low-dose corticosteroids and cyclosporine. While we observed remarkable improvement in her condition—she transitioned to nasal cannulae just 24 hours after starting treatment—it's essential to remember that vitamin C was not the sole intervention applied. This dual approach complicates our ability to isolate the specific benefits of vitamin C on psoriasis.
Ultimately, while the inclusion of vitamin C shows promise, we must acknowledge the lack of definitive evidence connecting it directly to improvements in psoriasis on its own. The dramatic recovery of the patient suggests a multifaceted treatment effect rather than a singular benefit from vitamin C.
In evaluating her treatment, we noted that vitamin C was part of a comprehensive regimen that also included low-dose corticosteroids and cyclosporine. While we observed remarkable improvement in her condition—she transitioned to nasal cannulae just 24 hours after starting treatment—it's essential to remember that vitamin C was not the sole intervention applied. This dual approach complicates our ability to isolate the specific benefits of vitamin C on psoriasis.
Ultimately, while the inclusion of vitamin C shows promise, we must acknowledge the lack of definitive evidence connecting it directly to improvements in psoriasis on its own. The dramatic recovery of the patient suggests a multifaceted treatment effect rather than a singular benefit from vitamin C.
Read More
8
Vitamin C's role in psoriasis relief
Effects of VitabridC on Skin Inflammation.
Moderate importance; composition complicates results
We explored the anti-inflammatory effects of VitabridC, a unique formulation combining vitamin C with lamellar zinc oxide, on psoriasis. This study specifically looked at how this combination treatment could influence the symptoms of psoriasis in mice.
We observed that when VitabridC was applied to mice with imiquimod-induced psoriasis, there were notable improvements. The treatment led to a reduction in epidermal thickness and significantly decreased the infiltration of inflammatory cells, which are key contributors to the painful and visible symptoms of psoriasis.
Furthermore, VitabridC also lowered the expression of various proinflammatory substances that typically escalate psoriatic conditions, such as interleukin-1 beta, tumor necrosis factor-alpha, and others. This suggests that vitamin C, alongside its unique delivery method, could play a beneficial role in managing psoriasis symptoms.
Overall, our findings indicate that VitabridC might serve as a promising treatment option for individuals suffering from psoriasis, potentially offering them relief from inflammation and discomfort.
We observed that when VitabridC was applied to mice with imiquimod-induced psoriasis, there were notable improvements. The treatment led to a reduction in epidermal thickness and significantly decreased the infiltration of inflammatory cells, which are key contributors to the painful and visible symptoms of psoriasis.
Furthermore, VitabridC also lowered the expression of various proinflammatory substances that typically escalate psoriatic conditions, such as interleukin-1 beta, tumor necrosis factor-alpha, and others. This suggests that vitamin C, alongside its unique delivery method, could play a beneficial role in managing psoriasis symptoms.
Overall, our findings indicate that VitabridC might serve as a promising treatment option for individuals suffering from psoriasis, potentially offering them relief from inflammation and discomfort.
Read More
Most Useful Reviews
8.8
Improved skin condition
Excellent! It's easy to drink and dissolves quickly in water, tasting just like lemon water. I'm pleased with the ample quantity provided. After giving it to my child, my dry arms and red psoriasis arms improved significantly within a week. The entire family is delighted.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.2
- All Researches
9
Pustular psoriasis treatment insights
ARDS complicating pustular psoriasis: treatment with low-dose corticosteroids, vitamin C and thiamine.
Combined treatments complicate results
We examined a case involving a 45-year-old woman with a history of psoriasis who developed serious respiratory distress attributed to a pustular flare of her skin condition. Admitted to the intensive care unit, she presented with acute symptoms, including a diffuse rash and difficulty breathing, alongside findings consistent with non-cardiogenic pulmonary edema.
In evaluating her treatment, we noted that vitamin C was part of a comprehensive regimen that also included low-dose corticosteroids and cyclosporine. While we observed remarkable improvement in her condition—she transitioned to nasal cannulae just 24 hours after starting treatment—it's essential to remember that vitamin C was not the sole intervention applied. This dual approach complicates our ability to isolate the specific benefits of vitamin C on psoriasis.
Ultimately, while the inclusion of vitamin C shows promise, we must acknowledge the lack of definitive evidence connecting it directly to improvements in psoriasis on its own. The dramatic recovery of the patient suggests a multifaceted treatment effect rather than a singular benefit from vitamin C.
In evaluating her treatment, we noted that vitamin C was part of a comprehensive regimen that also included low-dose corticosteroids and cyclosporine. While we observed remarkable improvement in her condition—she transitioned to nasal cannulae just 24 hours after starting treatment—it's essential to remember that vitamin C was not the sole intervention applied. This dual approach complicates our ability to isolate the specific benefits of vitamin C on psoriasis.
Ultimately, while the inclusion of vitamin C shows promise, we must acknowledge the lack of definitive evidence connecting it directly to improvements in psoriasis on its own. The dramatic recovery of the patient suggests a multifaceted treatment effect rather than a singular benefit from vitamin C.
Read More
8
DDH-1 shows psoriasis improvement
Ascorbic acid derivative DDH-1 ameliorates psoriasis-like skin lesions in mice by suppressing inflammatory cytokine expression.
Directly related to vitamin C use.
We explored the potential of DDH-1, a unique derivative of ascorbic acid, in treating psoriasis, a chronic inflammatory skin condition driven by certain cytokines. In our research, mice with psoriasis-like skin lesions induced by imiquimod were treated with DDH-1 to examine its effects on inflammatory markers.
During our study, we found that treatment with DDH-1 significantly reduced the expression of inflammatory cytokines IL-1β and TNF-α in the affected skin. This finding is crucial, as these cytokines are key players in the development and persistence of psoriasis.
Additionally, we observed noticeable improvement in the skin lesions of the mice following the application of DDH-1. These promising results indicate that DDH-1 may be beneficial for those looking to manage psoriasis and could serve as a supplement in treatment strategies.
During our study, we found that treatment with DDH-1 significantly reduced the expression of inflammatory cytokines IL-1β and TNF-α in the affected skin. This finding is crucial, as these cytokines are key players in the development and persistence of psoriasis.
Additionally, we observed noticeable improvement in the skin lesions of the mice following the application of DDH-1. These promising results indicate that DDH-1 may be beneficial for those looking to manage psoriasis and could serve as a supplement in treatment strategies.
Read More
8
Vitamin C's role in psoriasis relief
Effects of VitabridC on Skin Inflammation.
Moderate importance; composition complicates results
We explored the anti-inflammatory effects of VitabridC, a unique formulation combining vitamin C with lamellar zinc oxide, on psoriasis. This study specifically looked at how this combination treatment could influence the symptoms of psoriasis in mice.
We observed that when VitabridC was applied to mice with imiquimod-induced psoriasis, there were notable improvements. The treatment led to a reduction in epidermal thickness and significantly decreased the infiltration of inflammatory cells, which are key contributors to the painful and visible symptoms of psoriasis.
Furthermore, VitabridC also lowered the expression of various proinflammatory substances that typically escalate psoriatic conditions, such as interleukin-1 beta, tumor necrosis factor-alpha, and others. This suggests that vitamin C, alongside its unique delivery method, could play a beneficial role in managing psoriasis symptoms.
Overall, our findings indicate that VitabridC might serve as a promising treatment option for individuals suffering from psoriasis, potentially offering them relief from inflammation and discomfort.
We observed that when VitabridC was applied to mice with imiquimod-induced psoriasis, there were notable improvements. The treatment led to a reduction in epidermal thickness and significantly decreased the infiltration of inflammatory cells, which are key contributors to the painful and visible symptoms of psoriasis.
Furthermore, VitabridC also lowered the expression of various proinflammatory substances that typically escalate psoriatic conditions, such as interleukin-1 beta, tumor necrosis factor-alpha, and others. This suggests that vitamin C, alongside its unique delivery method, could play a beneficial role in managing psoriasis symptoms.
Overall, our findings indicate that VitabridC might serve as a promising treatment option for individuals suffering from psoriasis, potentially offering them relief from inflammation and discomfort.
Read More
7
Vitamin C influences psoriasis genes
Modulation of LXR-α and the effector genes by Ascorbic acid and Statins in psoriatic keratinocytes.
Vitamin C's combined effects noted.
We investigated how vitamin C, in combination with other treatments, impacts the expression of key genes linked to psoriasis in keratinocytes, the skin cells that are affected in this condition. Our research focused on LXR-α, a nuclear receptor that regulates gene expression and is known to play an important role in skin health.
By using a combination of ascorbic acid (vitamin C) and statins, particularly atorvastatin along with a specific form of cholesterol, we aimed to see how these treatments could influence the gene's activity and its target genes, including the vitamin D receptor and catalase.
The study showed that treatment with atorvastatin combined with 22R-hydroxycholesterol significantly increased LXR-α gene expression by 55%, whereas vitamin C paired with the same cholesterol form resulted in a 24% increase. Both treatments notably boosted the activity of the vitamin D receptor and catalase in psoriatic keratinocytes, suggesting that these compounds may help enhance certain protective mechanisms in the skin.
While both treatments proved beneficial in upregulating LXR-α and its targets, caution is warranted. Since the effect of vitamin C could not be isolated due to its use alongside statins, further research is needed to better understand its standalone impact on psoriasis.
By using a combination of ascorbic acid (vitamin C) and statins, particularly atorvastatin along with a specific form of cholesterol, we aimed to see how these treatments could influence the gene's activity and its target genes, including the vitamin D receptor and catalase.
The study showed that treatment with atorvastatin combined with 22R-hydroxycholesterol significantly increased LXR-α gene expression by 55%, whereas vitamin C paired with the same cholesterol form resulted in a 24% increase. Both treatments notably boosted the activity of the vitamin D receptor and catalase in psoriatic keratinocytes, suggesting that these compounds may help enhance certain protective mechanisms in the skin.
While both treatments proved beneficial in upregulating LXR-α and its targets, caution is warranted. Since the effect of vitamin C could not be isolated due to its use alongside statins, further research is needed to better understand its standalone impact on psoriasis.
Read More
4
Vitamin C's mixed effects assessed
Role of Vitamin C on methotrexate-induced nephrotoxicity in psoriasis context: A preclinical assessment.
Combination effects limit clarity
We explored how vitamin C (vitC), a known antioxidant, affects kidney health in psoriasis patients using methotrexate (MTX), a common treatment for this skin condition. In a controlled study, we used a mouse model and divided subjects into six groups to evaluate different treatments, including vitamin C, MTX, and combinations of both.
The results were intriguing. While vitamin C appeared to help reduce kidney damage in the psoriasis environment, it had mixed effects when used alongside MTX. Instead of improving the condition, the combination actually worsened skin lesions and intensified kidney damage. Specifically, we noted increased renal tubular necrosis and oxidative stress when vitamin C was administered with MTX after inducing psoriasis-like symptoms in the mice.
Thus, our findings clarify that while vitamin C may offer some protective benefits in certain contexts, it could be detrimental for psoriasis patients undergoing MTX treatment, especially those with existing kidney issues. It suggests careful consideration before combining these treatments in clinical practice.
The results were intriguing. While vitamin C appeared to help reduce kidney damage in the psoriasis environment, it had mixed effects when used alongside MTX. Instead of improving the condition, the combination actually worsened skin lesions and intensified kidney damage. Specifically, we noted increased renal tubular necrosis and oxidative stress when vitamin C was administered with MTX after inducing psoriasis-like symptoms in the mice.
Thus, our findings clarify that while vitamin C may offer some protective benefits in certain contexts, it could be detrimental for psoriasis patients undergoing MTX treatment, especially those with existing kidney issues. It suggests careful consideration before combining these treatments in clinical practice.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Improved skin condition
Excellent! It's easy to drink and dissolves quickly in water, tasting just like lemon water. I'm pleased with the ample quantity provided. After giving it to my child, my dry arms and red psoriasis arms improved significantly within a week. The entire family is delighted.
