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SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.2
USERS' SCORE
Moderately Good
Based on 1 Review
7.8
Supplement Facts
Serving Size: 1 Spray (Approx. 0.41 ml)
Amount Per Serving
%DV
Vitamin B12(as Methylcobalamin from Saccharomyces cerevisiae)
500 mcg
20,833%
Certified Organic Food BlendOrganic Beet (root), Organic Carrot (root), Organic Spinach (leaf), Organic Broccoli (flower & stem), Organic Tomato (fruit), Organic Kale (leaf), Organic Cabbage (leaf), Organic Parsley (leaf), Organic Brussels Sprout (leaf), Organic Green Bell Pepper (fruit), Organic Cucumber (gourd), Organic Celery (stalk), Organic Garlic (bulb), Organic Ginger (root), Organic Onion (root), Organic Cauliflower (flower & stem), Organic Asparagus (flower & stem), Organic Strawberry (fruit), Organic Cherry (fruit), Organic Blackberry (fruit), Organic Blueberry (fruit), Organic Raspberry (fruit)
2 mg
+
Top Medical Research Studies
8
Hydrothermal yeast impacts breast cancer
Hydrothermal treatment of yeast cell wall generates potent anti-proliferative agents targeting MCF7 breast cancer cells effectively even under culture conditions separated by a plastic wall.
High significance for cancer research
We investigated the ability of a hydrothermally treated yeast cell wall to fight against MCF-7 breast cancer cells. This innovative method improved solubility and produced a potent anti-proliferative agent.
The treatment significantly reduced cancer cell growth by nearly 59%, even when separated by a plastic barrier.
This suggests that a diffusible factor in the treated yeast contributes to this anti-cancer effect, likely linked to reactive carbon species generated during treatment.
Overall, our findings hint at a promising potential for this approach in cancer therapy development.
The treatment significantly reduced cancer cell growth by nearly 59%, even when separated by a plastic barrier.
This suggests that a diffusible factor in the treated yeast contributes to this anti-cancer effect, likely linked to reactive carbon species generated during treatment.
Overall, our findings hint at a promising potential for this approach in cancer therapy development.
Read More
7
Engineered yeast for cancer therapy
Yeast paves the way for cancer immunotherapy.
Promising immunotherapy delivery system
We explored an innovative system using Saccharomyces cerevisiae var. boulardii that secretes immune checkpoint inhibitors. This method has shown promise in reducing intestinal tumor loads, presenting a potential breakthrough in cancer immunotherapy.
The study highlights the engineered yeast's ability to safely deliver biologics, enhancing their effectiveness. While it’s still early days, the potential for such treatments could change how we approach cancer treatment in the future.
The study highlights the engineered yeast's ability to safely deliver biologics, enhancing their effectiveness. While it’s still early days, the potential for such treatments could change how we approach cancer treatment in the future.
Read More
7
Vitamin B12 and lymphoma association
Circulating levels of vitamins and risk of lymphoma: insights from a two-sample Mendelian randomization.
Significant link established, further research needed
We aimed to understand how levels of vitamin B12 might influence the risk of developing lymphoma, a type of cancer that affects the lymphatic system. Using data from comprehensive genome-wide association studies, we assessed the potential genetic links between circulating vitamin levels and lymphoma.
Our analysis particularly focused on vitamin B12 along with other vitamins, utilizing robust methods to ensure reliable results. We discovered that higher levels of vitamin B12 showed a noticeable association with a lower risk of lymphoma, indicating that it might play a beneficial role in cancer prevention. Interestingly, we also found similar results for folic acid, suggesting that these vitamins could have important implications for lymphoma risk overall.
However, it's essential to note that while our findings are promising, the evidence isn't definitive. Further research is needed to explore these relationships in greater depth and to understand the mechanisms behind them. Understanding how vitamins like B12 affect cancer could lead to better preventive strategies in the future.
Our analysis particularly focused on vitamin B12 along with other vitamins, utilizing robust methods to ensure reliable results. We discovered that higher levels of vitamin B12 showed a noticeable association with a lower risk of lymphoma, indicating that it might play a beneficial role in cancer prevention. Interestingly, we also found similar results for folic acid, suggesting that these vitamins could have important implications for lymphoma risk overall.
However, it's essential to note that while our findings are promising, the evidence isn't definitive. Further research is needed to explore these relationships in greater depth and to understand the mechanisms behind them. Understanding how vitamins like B12 affect cancer could lead to better preventive strategies in the future.
Read More
Most Useful Reviews
1.3
Risky dosage warning
20833% RDA is excessive. Such extreme levels in any supplement are unhealthy. Excess vitamin B12 may increase cancer risk, according to studies. A headache soon after taking it can indicate the body struggles to cope with such large amounts. Manufacturers promote high dosages since they are inexpensive to produce, but this does not ensure efficacy. It’s advisable to use only a small amount daily to gain benefits without the undesirable risks and side effects.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.2
8
Cancer-targeting yeast technology
Lysosome-Targeting Chimera Using Mannose-6-Phosphate Glycans Derived from Glyco-Engineered Yeast.
High significance due to advancements
We explored a new treatment mechanism using a formulation called LYTAC that employs glyco-engineered yeast-derived glycans for targeting cancer cells. This method taps into the body’s natural lysosomal degradation system to remove a protein linked to tumors.
In our study, LYTAC demonstrated the ability to effectively degrade the PD-L1 protein, which is known to inhibit T cell activity against cancer. Not only did it show greater effectiveness compared to traditional treatments, but it also highlights an innovative approach that could play a vital role in advancing cancer therapies.
In our study, LYTAC demonstrated the ability to effectively degrade the PD-L1 protein, which is known to inhibit T cell activity against cancer. Not only did it show greater effectiveness compared to traditional treatments, but it also highlights an innovative approach that could play a vital role in advancing cancer therapies.
Read More
8
Hydrothermal yeast impacts breast cancer
Hydrothermal treatment of yeast cell wall generates potent anti-proliferative agents targeting MCF7 breast cancer cells effectively even under culture conditions separated by a plastic wall.
High significance for cancer research
We investigated the ability of a hydrothermally treated yeast cell wall to fight against MCF-7 breast cancer cells. This innovative method improved solubility and produced a potent anti-proliferative agent.
The treatment significantly reduced cancer cell growth by nearly 59%, even when separated by a plastic barrier.
This suggests that a diffusible factor in the treated yeast contributes to this anti-cancer effect, likely linked to reactive carbon species generated during treatment.
Overall, our findings hint at a promising potential for this approach in cancer therapy development.
The treatment significantly reduced cancer cell growth by nearly 59%, even when separated by a plastic barrier.
This suggests that a diffusible factor in the treated yeast contributes to this anti-cancer effect, likely linked to reactive carbon species generated during treatment.
Overall, our findings hint at a promising potential for this approach in cancer therapy development.
Read More
8
Engineered yeast protects heart health
Butyrate-engineered yeast activates Nppa and Sgcg genes and reduces radiation-induced heart damage via the gut-heart axis.
High relevance, significant findings
We investigated the effects of engineered yeast that produces butyrate on heart damage caused by cancer radiotherapy. This study demonstrated that the yeast assists in maintaining intestinal health, which in turn significantly reduces heart tissue damage during radiation treatment.
By increasing beneficial gut bacteria and activating certain genes, the engineered yeast helps mitigate the harsh side effects of radiotherapy. This brings a promising avenue for improving cancer treatment and protecting vital organs, ultimately enhancing patient care.
By increasing beneficial gut bacteria and activating certain genes, the engineered yeast helps mitigate the harsh side effects of radiotherapy. This brings a promising avenue for improving cancer treatment and protecting vital organs, ultimately enhancing patient care.
Read More
8
Dendrobium improves oral mucositis
Effect of Dendrobium Officinale on Radioactive Oral Mucositis of Nasopharyngeal Carcinoma and Changes of Oral Microecology.
Limited isolated B12 benefits
We explored the effects of Dendrobium officinale, combined with vitamin B12, on patients suffering from oral mucositis due to radiotherapy for nasopharyngeal cancer. In a well-structured study conducted at Zhejiang Cancer Hospital, we involved sixty patients, dividing them into two groups. One group received Dendrobium tea alongside vitamin B12, while the other group was given vitamin B12 alone.
Our focus was to determine how this combination could help alleviate the harsh side effects of radiotherapy, particularly the inflammation and pain associated with oral mucositis. After a month of treatment, we evaluated several factors, such as salivary flow and levels of specific immune markers in the patients' blood and saliva.
Interestingly, we discovered that Dendrobium officinale showed potential in improving oral mucositis symptoms through better salivary gland function and modifications to the oral microbiome. Though vitamin B12 was part of the treatment, it wasn’t isolated in our findings. As a result, we cannot definitively speak about its specific benefits on its own without acknowledging the combined effects with Dendrobium.
Overall, our findings highlight the promise of Dendrobium officinale in addressing oral complications from cancer treatment, yet the role of vitamin B12 remains intertwined and less distinct in this context.
Our focus was to determine how this combination could help alleviate the harsh side effects of radiotherapy, particularly the inflammation and pain associated with oral mucositis. After a month of treatment, we evaluated several factors, such as salivary flow and levels of specific immune markers in the patients' blood and saliva.
Interestingly, we discovered that Dendrobium officinale showed potential in improving oral mucositis symptoms through better salivary gland function and modifications to the oral microbiome. Though vitamin B12 was part of the treatment, it wasn’t isolated in our findings. As a result, we cannot definitively speak about its specific benefits on its own without acknowledging the combined effects with Dendrobium.
Overall, our findings highlight the promise of Dendrobium officinale in addressing oral complications from cancer treatment, yet the role of vitamin B12 remains intertwined and less distinct in this context.
Read More
8
Combining treatments reduces HPV positivity
Treatment with Epigallocatechin Gallate, Folic Acid, Vitamin B12, and Hyaluronic Acid Decreases HPV Positivity in Women Attending Regional Screening in Puglia.
Indicates value of combination therapy
We explored how vitamin B12, alongside other natural compounds, impacts HPV positivity in women at risk of cervical cancer. Our study involved 163 women who had either tested positive for HPV or had a history of HPV infections. They were divided into two groups: one group received a specific oral treatment containing vitamin B12 along with other ingredients for three months, while the other group underwent standard clinical monitoring.
After this period, we found that the group receiving the combination treatment showed a significant decrease in HPV positivity compared to the control group. Importantly, not only did vitamin B12 play a role in the treatment, but it was the combination of all four components—EGCG, folic acid, vitamin B12, and hyaluronic acid—that appeared particularly effective in improving the condition of their cervical health.
While vitamin B12's isolated effect on cancer isn't directly measurable from this study, we observed considerable improvements in cervical lesions as well, suggesting that this regimen may help manage HPV-related risks. This highlights the potential for natural treatments in women's health, particularly in reducing the burden of HPV, which is a critical concern for cancer prevention.
After this period, we found that the group receiving the combination treatment showed a significant decrease in HPV positivity compared to the control group. Importantly, not only did vitamin B12 play a role in the treatment, but it was the combination of all four components—EGCG, folic acid, vitamin B12, and hyaluronic acid—that appeared particularly effective in improving the condition of their cervical health.
While vitamin B12's isolated effect on cancer isn't directly measurable from this study, we observed considerable improvements in cervical lesions as well, suggesting that this regimen may help manage HPV-related risks. This highlights the potential for natural treatments in women's health, particularly in reducing the burden of HPV, which is a critical concern for cancer prevention.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 1 Review
7.8
1.3
Risky dosage warning
20833% RDA is excessive. Such extreme levels in any supplement are unhealthy. Excess vitamin B12 may increase cancer risk, according to studies. A headache soon after taking it can indicate the body struggles to cope with such large amounts. Manufacturers promote high dosages since they are inexpensive to produce, but this does not ensure efficacy. It’s advisable to use only a small amount daily to gain benefits without the undesirable risks and side effects.
Read More
