Turmeric Curcumin
10
Achieved remission
Most Useful Review
I have been taking 2 gms (4 capsules) of curcumin daily since my stage 4 breast cancer diagnosis a year ago. Remarkably, I went into remission within three months, and there has been no evidence of cancer for the past eight months.
9.5
Cancer remission
Most Useful Review
After taking curcumin for about four months, I noticed a significant boost in my immune system. I also recommended it to my aunt, who had stage 4 lymphoma, and I am thrilled to share that her cancer has gone into remission after about a month on it.
Enzymes
9
Nattokinase improves cancer therapy
Engineered bacteria breach tumor physical barriers to enhance radio-immunotherapy.
Most Relevant Research
We explored the role of a unique engineered strain of Salmonella, which secretes a substance called nattokinase, in improving cancer treatment—specifically radio-immunotherapy for colon tumors. This inventive approach aims to address an important challenge in cancer therapy: the physical barriers in the tumor microenvironment that often prevent immune cells from effectively targeting cancer cells.
The engineered bacteria, which we refer to as VNP, is designed to accumulate at tumor sites after being introduced into the body. Once there, these bacteria produce large amounts of nattokinase, a compound that helps break down a protein called fibronectin, clear out the surrounding tissue structure, and reduce the presence of cells that typically support tumor growth—known as cancer-associated fibroblasts.
By breaking down these barriers, VNP allows vital immune cells, specifically dendritic cells, to enter the tumor more easily. After treatment with radiotherapy, this infiltration leads to an enhanced immune response, recruiting CD8 T cells that work to eliminate tumor cells. We noticed that treating tumors with VNP before radiotherapy not only amplified the targeted effect but also established lasting immune memory, which may help prevent tumor recurrence and metastasis.
Our findings suggest that using engineered bacteria like VNP to breach physical barriers within tumors could significantly enhance the effectiveness of radio-immunotherapy, offering promising insights for future cancer treatments.
The engineered bacteria, which we refer to as VNP, is designed to accumulate at tumor sites after being introduced into the body. Once there, these bacteria produce large amounts of nattokinase, a compound that helps break down a protein called fibronectin, clear out the surrounding tissue structure, and reduce the presence of cells that typically support tumor growth—known as cancer-associated fibroblasts.
By breaking down these barriers, VNP allows vital immune cells, specifically dendritic cells, to enter the tumor more easily. After treatment with radiotherapy, this infiltration leads to an enhanced immune response, recruiting CD8 T cells that work to eliminate tumor cells. We noticed that treating tumors with VNP before radiotherapy not only amplified the targeted effect but also established lasting immune memory, which may help prevent tumor recurrence and metastasis.
Our findings suggest that using engineered bacteria like VNP to breach physical barriers within tumors could significantly enhance the effectiveness of radio-immunotherapy, offering promising insights for future cancer treatments.
9.5
Effective cancer treatment
Most Useful Review
My favourite dietary supplement! Serrapeptase is one of the safest and most effective anti-inflammatory drugs, gently breaking down fibrous formations. It has helped with conditions related to cancer, promotes normal blood flow, and cleanses toxins. I have taken it regularly, and it feels like a nanoscalpel with no side effects. I appreciate its benefits and will keep buying it.
Ester C
9
Vitamin C enhances immune response
Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response.
Most Relevant Research
We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
10
Cancer support benefits
Most Useful Review
I consistently assert that these vitamins are essential and should be a staple in every household. My experience with ayherb has proven their worth multiple times. Vitamin C aids the body in producing collagen, assimilating chondroprotectors, and fighting free radicals, while enhancing immunity. It protects against winter colds and summer oedema. The Nobel laureate Linus Pauling demonstrated its ability to destroy cancer stem cells. Caring for loved ones includes ensuring they receive these essential vitamins. Wishing you and your family good health.
Alpha Lipoic Acid
9
Alpha-lipoic acid aids recovery
Randomized controlled trial of bromelain and alpha-lipoic acid in breast conservative surgery.
Most Relevant Research
We conducted a thorough analysis to determine how alpha-lipoic acid, in combination with other supplements, affects early complications like edema and seroma following breast-conserving surgery (BCS). Our study was structured as a double-blind, randomized, placebo-controlled trial involving 114 participants over a span of three years.
Participants were divided into three groups, with one group receiving a mix of Casperome™-Boswellia Phytosome and bromelain along with alpha-lipoic acid, while the other groups received either bromelain with a placebo or just a placebo. Over a period of 30 days, we gathered data on the effectiveness of these treatments.
Our findings revealed that the combination of bromelain and alpha-lipoic acid significantly reduced the incidence of edema and seroma compared to the placebo. Specifically, after one month, we observed marked improvements in patients who received the active treatment. This research highlights the potential therapeutic benefits of alpha-lipoic acid, especially when used with other agents, in managing early complications that can follow breast surgery. Although it’s important to note that the specific isolating effects of alpha-lipoic acid on its own were challenging to determine, the results offer a promising glimpse into its use in surgical recovery.
Participants were divided into three groups, with one group receiving a mix of Casperome™-Boswellia Phytosome and bromelain along with alpha-lipoic acid, while the other groups received either bromelain with a placebo or just a placebo. Over a period of 30 days, we gathered data on the effectiveness of these treatments.
Our findings revealed that the combination of bromelain and alpha-lipoic acid significantly reduced the incidence of edema and seroma compared to the placebo. Specifically, after one month, we observed marked improvements in patients who received the active treatment. This research highlights the potential therapeutic benefits of alpha-lipoic acid, especially when used with other agents, in managing early complications that can follow breast surgery. Although it’s important to note that the specific isolating effects of alpha-lipoic acid on its own were challenging to determine, the results offer a promising glimpse into its use in surgical recovery.
9.5
Promotes recovery
Most Useful Review
I brought this for my dad who has cancer. It offers powerful antioxidants and aids in cell renewal. I pray for my father's recovery.
Green Tea Extract
9
Vitamin C enhances immune response
Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response.
Most Relevant Research
We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
9.5
Stops cancer development
Most Useful Review
My moles stopped itching after I began taking green tea extract for cardiovascular health. After a stroke, I noticed changes and started the extract. In weeks, the itching subsided; I later learned it’s a strong antioxidant preventing cancer and slowing ageing.
Resveratrol
9.5
Inflammation relief
Most Useful Review
Resveratrol is an excellent, tested product that aids in preventing cancer and relieving inflammation. After suffering from increased leukocyte levels for years, I took Resveratrol for four months, and subsequent tests showed normal results. Now, I take it twice a year for prevention.
9.5
Cancer therapy
Most Useful Review
Resveratrol is a well-studied natural compound with antioxidant properties. It is known to be anti-cancer and serves as a therapeutic agent.
Ascorbic Acid
9
Vitamin C enhances immune response
Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response.
Most Relevant Research
We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
9.5
Natural medicine benefits
Most Useful Review
Few people realise that this is the best natural medicine! I haven’t been ill for years; I can’t even remember what a runny nose feels like. It’s remarkable to consider taking 200g per day, especially with serious conditions like cancer. I took 30g daily for candida, and it worked perfectly. Our bodies are well-equipped for all illnesses but occasionally need our assistance, and that’s where this comes in. I avoid medications, only taking vitamins, and everything is well.
Vitamin C
9
Vitamin C enhances immune response
Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response.
Most Relevant Research
We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
9.5
Essential for therapy
Most Useful Review
Vitamin C is remarkably effective, especially in cancer therapy. Many people underestimate the importance of bioflavonoids which are essential for its effectiveness. These capsules have proven beneficial, showing significant efficacy in combating cancer cells.
Spirulina
9.5
Cancer treatment benefits
Most Useful Review
Spirulina is a source of plant protein and B vitamins, particularly B12, making it beneficial for vegetarians. While it aids in weight loss, healthy eating and exercise are still essential. Spirulina boosts the immune system, helps with anemia by increasing hemoglobin, and has anti-cancer properties through phycocyanin, which can inhibit cancer cell growth. It is vital to use it in moderation and consider its effects on the body.
9.5
Antioxidant properties
Most Useful Review
Spirulina is rich in phytochemicals like phycocyanin, which are powerful antioxidants. They help reduce oxidative damage, protect against cancer, and lower heart disease risk.
Multivitamins
9.5
Skin cancer prevention
Most Useful Review
My GP, who practices integrative medicine, recommended superantioxidants years ago for my skin cancer issues. After consistently taking one a day, I enjoyed a seven-year period without basal cell cancers. However, after neglecting them, I developed one more BBC and a melanoma, which prompted me to resume regular use. I plan to take them forever, as my sun protection routine remained unchanged during this time.
9.5
Effective prevention
Most Useful Review
This vitamin complex is a real godsend! Compared to Russian pharmacy brands, the potency of each microelement and vitamin is significantly greater, offering a more effective impact on the body. The dosage is perfect for an adult woman. I particularly valued the high selenium content, which is excellent for cancer prevention. I highly recommend these vitamins to my relatives and friends.
Pectin
9.5
Prevents colon cancer
Most Useful Review
I took pectin to eliminate heavy metals and normalise digestion, and it successfully performed both tasks, acting as a sponge to cleanse our bodies. It captures toxins and waste products, ensuring harmful substances do not linger in the intestines, thus helping to prevent colon cancer. Pectin also provides a feeling of fullness, which is important for those aiming to lose weight, reduces putrefaction in the intestines, purges toxins, heals the intestinal mucosa, and enhances vitamin and mineral absorption from food, except iron.
10
Colon cancer relief
Most Useful Review
Excellent! This product has saved me from colon cancer.
D Mannose
10
Reduced UTIs significantly
Most Useful Review
After severe surgical treatment for cancer, I was plagued by UTIs requiring antibiotics monthly for over three years, leaving my gut flora depleted. I tried numerous remedies until discovering D-Mannose. My surgeon approves, stating there's little more he can offer. I've almost completely eliminated UTIs, and taking two 500mg capsules at night has reduced them by at least 95%. This product has been a true blessing for me.
9.5
Helps stage IV cancer
Most Useful Review
I am taking this for Stage IV breast cancer alongside D-Mannose, which my integrative doctor says targets cancer cells. Since it has spread to my brain, bones, liver, pericardium, and lungs, I'm willing to try anything. After finishing two bottles, I am starting to feel better.
Collagen Supplements
9.5
Relieved discomfort
Most Useful Review
Praise! Following my treatment for breast cancer, I took the anti-hormone drug Sodium Dipyridoxine, which caused severe pain in my hand and foot joints. Thankfully, UCII has improved my joint health and relieved the discomfort significantly. I'm a fan of Now Foods; it's safe and effective, and I will definitely continue to repurchase it.
9.5
Significant improvement
Most Useful Review
My first choice for joint care! Over the past year, I increased my exercise to combat cancer, resulting in hip and knee joint pain. Taking one UCII pill every morning and evening has been transformative. After two months, the pain has vanished completely. My wife encourages me to continue using it, and I highly recommend it without reservation.
Iron
9
Iron oxide NPs enhance cancer treatment
Universal Chiral Nanopaint for Metal Oxide Biomaterials.
Most Relevant Research
We delved into how iron oxide nanoparticles (NPs), when enhanced with a special chiral nanopaint, can impact cancer treatment. Our focus was on comparing two forms of these nanoparticles: the d-nanopainted versions and their l-nanopainted counterparts. We discovered that the d-nanopainted iron oxide NPs had over 50% higher cellular uptake by cancer cells. This increase was linked to the way these chiral NPs interacted specifically with receptors on the cell surfaces.
Moreover, in testing on living subjects, the d-nanopainted iron oxide NPs demonstrated a striking four-fold improvement in anticancer efficiency through magnetic hyperthermia. This was attributed to their better ability to adhere to tumor tissues compared to the l-nanopainted version. Thus, we see that the innovative use of chiral nanopaint appears to significantly enhance the effectiveness of iron oxide nanoparticles in cancer treatments, marrying magnetism with chirality for promising biomedical applications.
Moreover, in testing on living subjects, the d-nanopainted iron oxide NPs demonstrated a striking four-fold improvement in anticancer efficiency through magnetic hyperthermia. This was attributed to their better ability to adhere to tumor tissues compared to the l-nanopainted version. Thus, we see that the innovative use of chiral nanopaint appears to significantly enhance the effectiveness of iron oxide nanoparticles in cancer treatments, marrying magnetism with chirality for promising biomedical applications.
9.5
Significant improvement
Most Useful Review
These pills are excellent. My father is a cancer patient and was incredibly weak with a hemoglobin level of just 50 in August. After two months of taking these pills, his hemoglobin rose to 106. I’m really pleased with the results.
Sodium Ascorbate
9
Vitamin C enhances immune response
Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response.
Most Relevant Research
We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
10
Breast cancer support
Most Useful Review
My wife is living with breast cancer, which is being managed partly by using sodium ascorbate mixed with sterile water for injection, infused every other day. It's a pure product that has proven effective in keeping her condition stable. Thank you for helping to keep her alive!
Selenium
9
Selenium improves colon cancer treatment
Efficacy Evaluation of Selenium-enriched Akkermansia muciniphila in the Treatment of Colon Tumor Mice.
Most Relevant Research
We aimed to understand the impact of selenium-enriched Akkermansia muciniphila (Se-AM) on colon cancer, specifically looking at its effectiveness in treating tumors in mice. By enriching the probiotics with inorganic selenium, we prepared Se-AM and evaluated its performance against colon cancer cells using a mouse model.
Our findings revealed that Se-AM was effective in killing colon cancer cells, notably the CT26 cells. The effectiveness seemed to depend on the concentration, indicating that higher doses were better at destroying these cancer cells. In addition to this direct killing effect, we saw that Se-AM played a therapeutic role in mice with established tumors by reducing tumor size and positively altering inflammatory markers in the colon.
Importantly, treatment with Se-AM restored gut microbiota diversity back to levels similar to healthy controls. We observed a notable increase in beneficial bacteria, which suggests that Se-AM not only addresses cancer cells but also promotes a healthier gut environment. Furthermore, we didn't find any adverse effects on vital organs in the mice, highlighting the safety of this treatment.
Overall, our work indicates that Se-enriched Akkermansia muciniphila has promising potential in the fight against colon cancer, providing both direct anti-cancer effects and supporting gut health.
Our findings revealed that Se-AM was effective in killing colon cancer cells, notably the CT26 cells. The effectiveness seemed to depend on the concentration, indicating that higher doses were better at destroying these cancer cells. In addition to this direct killing effect, we saw that Se-AM played a therapeutic role in mice with established tumors by reducing tumor size and positively altering inflammatory markers in the colon.
Importantly, treatment with Se-AM restored gut microbiota diversity back to levels similar to healthy controls. We observed a notable increase in beneficial bacteria, which suggests that Se-AM not only addresses cancer cells but also promotes a healthier gut environment. Furthermore, we didn't find any adverse effects on vital organs in the mice, highlighting the safety of this treatment.
Overall, our work indicates that Se-enriched Akkermansia muciniphila has promising potential in the fight against colon cancer, providing both direct anti-cancer effects and supporting gut health.
9.5
Anti-cancer properties
Most Useful Review
Selenium is recognised for its potent anti-cancer properties and is effective in preventing various diseases. Its roles in DNA repair and enhancing immune functions, along with antioxidant benefits, imply selenium's significant role in cancer prevention. Studies indicate that a daily intake of 200 mcg can notably lower the risk of colorectal, prostate, and lung cancers while reducing overall cancer-related mortality.
Herbal Extracts
9
Echinacea modulates gut health in cancer
Echinacea purpurea polysaccharide intervene in hepatocellular carcinoma via modulation of gut microbiota to inhibit TLR4/NF-κB pathway.
Most Relevant Research
We investigated how Echinacea purpurea polysaccharide (EPP) might help in fighting hepatocellular carcinoma, a common type of liver cancer. Our findings showed that EPP not only reduced liver damage caused by cancer but also helped in slowing down cancer cell growth and promoting their death, a process known as apoptosis.
An interesting aspect of our study was how EPP influenced gut microbiota. After treatment with EPP, we observed a significant increase in beneficial bacteria that produce propionic and butyric acids. These changes in gut microbes led to strengthening the intestinal barrier, which is crucial for keeping harmful substances like lipopolysaccharides (LPS) from leaking into the bloodstream. By controlling LPS leakage, EPP helped reduce inflammation and hindered the TLR4/NF-κB signaling pathway that cancer cells often exploit to survive.
On a molecular level, our metabolomics analysis revealed that EPP treatment downregulated certain metabolic pathways associated with tumor growth while enhancing butyrate metabolism, which is linked to healthier cellular functions. Overall, our research highlights EPP's potential to combat liver cancer through beneficial modifications to the gut microbiome and consequent impacts on inflammation and cancer cell survival.
An interesting aspect of our study was how EPP influenced gut microbiota. After treatment with EPP, we observed a significant increase in beneficial bacteria that produce propionic and butyric acids. These changes in gut microbes led to strengthening the intestinal barrier, which is crucial for keeping harmful substances like lipopolysaccharides (LPS) from leaking into the bloodstream. By controlling LPS leakage, EPP helped reduce inflammation and hindered the TLR4/NF-κB signaling pathway that cancer cells often exploit to survive.
On a molecular level, our metabolomics analysis revealed that EPP treatment downregulated certain metabolic pathways associated with tumor growth while enhancing butyrate metabolism, which is linked to healthier cellular functions. Overall, our research highlights EPP's potential to combat liver cancer through beneficial modifications to the gut microbiome and consequent impacts on inflammation and cancer cell survival.
8.8
Effective immunity boost
Most Useful Review
Excellent! The echinacea plant is well-known for enhancing immunity and combating cancer cells. It's particularly useful for those with immunodeficiency. I obtained it for my mother and noticed an improvement in her condition. I highly recommend this brand as its products are very effective and the results are remarkable.
Oregano Oil Supplements
9.5
Effective treatment
Most Useful Review
I have been battling basal cell cancer and tried everything, but oregano oil is the only treatment that worked for me. I applied it twice daily and took two drops under my tongue each time. It's remarkable. Thank you!
8.8
Immune support
Most Useful Review
I have cancer, and I discovered through a holistic doctor that wild oregano oil aids breast cancer patients. It keeps my immunity strong, especially when travelling. I managed to avoid illness, and it also helped my gums heal after dental work, without harming my gut flora. Its potent quality, particularly the Carvacrol concentration, is impressive.
Vitamin Bs
8
Niacin aids in leukemia treatment
Rapamycin and Niacin combination induces apoptosis and cell cycle arrest through autophagy activation on acute myeloid leukemia cells.
Most Relevant Research
We investigated how the combination of Niacin and Rapamycin affects the growth of acute myeloid leukemia (AML) cells. By conducting a series of experiments on two AML cell lines, THP-1 and NB4, we aimed to see if this duo could meaningfully target cancer cells.
Our findings showed that when used together, Rapamycin and Niacin significantly lowered the viability of the leukemia cells. Specifically, we observed notable increases in cell death, with THP-1 cells experiencing nearly five times more apoptosis, and NB4 cells showing a 7.3-fold increase. The combination treatment also caused a distinct halt in the cell cycle, meaning the cancer cells were not able to continue growing.
Additionally, we noted changes in various proteins linked to autophagy, a process that can help cells maintain balance. While there’s much to be understood, our results suggest that this combination of Niacin and Rapamycin may enhance the fight against AML by promoting cell death and disrupting the cell cycle.
Ultimately, this study highlights the potential of using a natural product like Niacin in a blend with traditional treatments like Rapamycin to combat cancer. However, further research is needed to fully understand the implications of these findings.
Our findings showed that when used together, Rapamycin and Niacin significantly lowered the viability of the leukemia cells. Specifically, we observed notable increases in cell death, with THP-1 cells experiencing nearly five times more apoptosis, and NB4 cells showing a 7.3-fold increase. The combination treatment also caused a distinct halt in the cell cycle, meaning the cancer cells were not able to continue growing.
Additionally, we noted changes in various proteins linked to autophagy, a process that can help cells maintain balance. While there’s much to be understood, our results suggest that this combination of Niacin and Rapamycin may enhance the fight against AML by promoting cell death and disrupting the cell cycle.
Ultimately, this study highlights the potential of using a natural product like Niacin in a blend with traditional treatments like Rapamycin to combat cancer. However, further research is needed to fully understand the implications of these findings.
9.5
Cancer protection
Most Useful Review
Folic acid is essential, especially for those preparing for pregnancy or with a deficiency. It offers powerful protection against cancer. This bottle contains the ideal form of folic acid for our bodies!
Cranberry
8.8
Cranberry cancer prevention
Most Useful Review
Cranberry is wonderful for combating diseases linked to urinary tract infections and plays a significant role in preventing cardiovascular diseases, ageing, and cancer. Furthermore, it helps maintain the balance of intestinal flora and boosts immune defences against infection.
8.8
Cranberry benefits cancer
Most Useful Review
The benefits of cranberry are numerous: it enhances immunity, addresses urinary tract issues, and prevents gastric problems including cancer. However, those with gastroesophageal reflux should avoid it. Cranberry can also support heart health, lower blood pressure, and reduce cholesterol. It may interact with certain medications, so consulting a doctor before consuming is advisable.
Bromelain
9.5
Enzyme therapy helps
Most Useful Review
I take the Shirochan Cancer Protocol as part of my systemic proteolytic enzymes, along with pancreatin, nattokinase, and serrapeptase, on an empty stomach. Enzyme therapy is crucial for cancer healing as it breaks down fibrin, which covers cancer cells, allowing our immune system to target them. It also mitigates chemotherapy side effects and is safe as it contains just enzymes. Your support in my natural cancer healing journey is greatly appreciated. Thank you!
9.5
Incredible for cancer
Most Useful Review
This product is incredibly effective for anyone battling cancer and is also beneficial against arthritis.
Coconut Supplements
9.5
Cancer risk reduction
Most Useful Review
Coconut oil is excellent for maintaining healthy fat levels, lowering the risks of atherosclerosis, cardiovascular disease, and even cancer. After consistent intake of 2-3 capsules daily, I noticed my hair shines, and my skin is well-nourished and moisturised.
8.8
Cancer treatment innovator
Most Useful Review
Beating cancer! I utilise these tablets and prepare food using quality fats like olive, MCT, coconut, and hemp oil while adhering to "THE KETO WAY" to maintain my state of ketosis.
Melatonin
9.5
Apoptosis enhancement
Most Useful Review
I take it for cancer purposes as numerous studies show high dosages (up to 160mg) significantly aid apoptosis. It's essential to increase the dosage gradually and consult your doctor before taking higher amounts. No side effects were reported at those levels, but it's better to be cautious.
9.5
Immune system support
Most Useful Review
Excellent! Melatonin supports the immune system and inhibits breast cancer development. It helps me sleep at night.
Vitamins
7
Vitamin D3’s role in cancer metabolism
Isotope tracing-assisted chip-based solid-phase extraction mass spectrometry for monitoring metabolic changes and vitamin D3 regulation in cells.
Most Relevant Research
We explored how vitamin D3 impacts cancer metabolism through an innovative chip-based solid-phase extraction mass spectrometry method. This approach allowed us to closely analyze the metabolic changes in both normal liver cells and cancer cells, providing a real-time view of how these processes work. With this technology, we could detect various metabolites at incredibly low concentrations, helping us form a clearer picture of cellular metabolism.
Our observations highlighted significant differences in metabolism between normal cells and cancerous ones, specifically noting increased glycolytic activity and higher lactate production in cancer cells. When we treated the cancer cells with 1,25-dihydroxyvitamin D3 (the active form of vitamin D3), we found that it suppressed glucose uptake and altered metabolic activity in one type of cancer cell, HCT116. This finding suggests that vitamin D3 could play a regulatory role in how cancer cells manage their energy and metabolize nutrients.
Overall, our study sheds light on the metabolic changes associated with cancer and points to vitamin D3 as a potential modulator of these processes. The insights gained could be valuable for developing new cancer therapies and understanding metabolic diseases better.
Our observations highlighted significant differences in metabolism between normal cells and cancerous ones, specifically noting increased glycolytic activity and higher lactate production in cancer cells. When we treated the cancer cells with 1,25-dihydroxyvitamin D3 (the active form of vitamin D3), we found that it suppressed glucose uptake and altered metabolic activity in one type of cancer cell, HCT116. This finding suggests that vitamin D3 could play a regulatory role in how cancer cells manage their energy and metabolize nutrients.
Overall, our study sheds light on the metabolic changes associated with cancer and points to vitamin D3 as a potential modulator of these processes. The insights gained could be valuable for developing new cancer therapies and understanding metabolic diseases better.
9.5
Supports immune system
Most Useful Review
I ordered it for my child, who liked it. This product has good quality, natural ingredients, and a pleasant taste. Vitamin C supports the active immune system, has antiviral, antibacterial, and anti-inflammatory effects, and helps prevent the occurrence of cancer. It also aids in the synthesis of hormones and promotes iron absorption, which is beneficial for maintaining energy levels.
Rutin
9.5
Reduces cancer risk
Most Useful Review
The element reduces the risk of developing cancer cells, particularly effective against blood and breast cancer. It also alleviates eye pressure. Rutin is a powerful ingredient that guarantees a reduction in intraocular pressure to a safe level.
9.5
Prevents multiple cancers
Most Useful Review
Sulforaphane is effective against stomach, bladder, and breast cancer, and possesses antibacterial properties. It induces self-destruction of tumours and lowers estrogen levels, making it beneficial for women, especially during the latter part of their cycle. For maximum sulforaphane content, broccoli should be prepared by chopping and resting before cooking.
Magnesium
8
Magnesium alloy inhibits cancer growth
Biodegradable Mg-1%Ca alloy inhibits the growth of cervical cancer.
Most Relevant Research
We explored how magnesium alloy, particularly a variant containing 1% calcium, impacts cervical cancer cells. Our investigation revealed that this alloy has promising antitumor properties which could pave the way for new treatments.
In our experiments, we tested the effects of the Mg-1%Ca alloy both in laboratory settings and in living organisms. This alloy was found to release magnesium ions and hydroxide ions more slowly than expected. We observed that it effectively inhibited the growth of cervical cancer cells, specifically SiHa and HeLa cell lines.
Additionally, the presence of the alloy induced apoptosis, or programmed cell death, in the cancer cells, disrupted their structural integrity, and hindered their ability to migrate and invade other tissues. Importantly, the Mg-1%Ca alloy was seen to influence key molecular pathways, specifically the MAPK/ERK signaling pathway, which plays a role in cancer cell proliferation.
With these results, it's evident that magnesium alloy could serve as a useful adjunct to current cervical cancer therapies, potentially helping to prevent both cancer growth and metastasis.
In our experiments, we tested the effects of the Mg-1%Ca alloy both in laboratory settings and in living organisms. This alloy was found to release magnesium ions and hydroxide ions more slowly than expected. We observed that it effectively inhibited the growth of cervical cancer cells, specifically SiHa and HeLa cell lines.
Additionally, the presence of the alloy induced apoptosis, or programmed cell death, in the cancer cells, disrupted their structural integrity, and hindered their ability to migrate and invade other tissues. Importantly, the Mg-1%Ca alloy was seen to influence key molecular pathways, specifically the MAPK/ERK signaling pathway, which plays a role in cancer cell proliferation.
With these results, it's evident that magnesium alloy could serve as a useful adjunct to current cervical cancer therapies, potentially helping to prevent both cancer growth and metastasis.
10
Recommended for cancer
Most Useful Review
I've been taking this for a few months now; it’s my second purchase. As a cancer patient, my magnesium levels were low, and my doctor advised long-term use. I found this product on IHerb and can highly recommend it.
Inositol
9
Myo-inositol affects prostate cancer cells
Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line.
Most Relevant Research
We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability.
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
9.5
Significant cancer support
Most Useful Review
IP6 is an incredible supplement, significantly reducing the formation of harmful AGEs that damage our organs and contribute to diabetes complications. Its ability to lower these substances by a remarkable 40% is impressive. I recommend taking it before meals for optimal effects. IP6 is also a powerful anti-cancer agent. For those with diabetes and insulin resistance, I've found it synergistic with other supplements and providing substantial overall protection and energy boost.
Quercetin
9.5
Quercetin enhances cancer treatment efficacy
Active tumor targeting by core-shell PDMS-HA nanoparticles with sequential delivery of doxorubicin and quercetin to overcome P-glycoprotein efflux pump.
Most Relevant Research
We explored the impact of quercetin when used alongside doxorubicin in treating breast cancer. In our study, we delivered these two compounds using specialized polydimethylsiloxane nanoparticles, which were designed to enhance their effectiveness in targeting cancer cells.
Quercetin plays a crucial role by blocking the P-glycoprotein efflux pump. This action helps increase the intracellular levels of doxorubicin, leading to better cell death and more effective treatment outcomes. The combination of these two agents helps to tackle the problem of cancer cell resistance to drugs, making it easier for treatment to work.
Our research demonstrated that the sequential delivery of doxorubicin followed by quercetin significantly reduced tumor size in experimental models compared to using either treatment alone. We observed noticeable cell death and inhibited tumor growth in the tested breast cancer cells.
Overall, the findings suggest that quercetin can effectively support chemotherapy by reversing drug resistance and enhancing the anticancer effects of doxorubicin when they are delivered together. The approach not only shows promise in bolstering treatment efficacy but also indicates minimal toxicity to normal tissues.
Quercetin plays a crucial role by blocking the P-glycoprotein efflux pump. This action helps increase the intracellular levels of doxorubicin, leading to better cell death and more effective treatment outcomes. The combination of these two agents helps to tackle the problem of cancer cell resistance to drugs, making it easier for treatment to work.
Our research demonstrated that the sequential delivery of doxorubicin followed by quercetin significantly reduced tumor size in experimental models compared to using either treatment alone. We observed noticeable cell death and inhibited tumor growth in the tested breast cancer cells.
Overall, the findings suggest that quercetin can effectively support chemotherapy by reversing drug resistance and enhancing the anticancer effects of doxorubicin when they are delivered together. The approach not only shows promise in bolstering treatment efficacy but also indicates minimal toxicity to normal tissues.
8.8
Improved wellbeing
Most Useful Review
I have multiple sclerosis, but this supplement has been stunningly effective. At 52, my health has improved significantly. Quercetin, a powerful antioxidant, along with bromelain, is helping my treatment against cancer. I only relied on these supplements and avoided antibiotics throughout my recovery. I consistently take them for ongoing health and quality of life.
Fiber
8.8
Anti-cancer effects
Most Useful Review
Curcumin is a remarkable dietary supplement and offers numerous health benefits, including anti-cancer properties. It is known for its anti-inflammatory and antioxidant effects, and studies suggest it may alleviate osteoarthritis and rheumatoid arthritis symptoms. Curcumin has been associated with improvements in cardiovascular health, mood, and memory. Additionally, taking it with phospholipids and piperine enhances its bioavailability, making it highly effective. I highly recommend it for anyone looking to boost their health and well-being.
9.5
Strengthens immunity
Most Useful Review
Garlic is excellent for the gut, enhancing enzyme secretion and digestion, while strengthening the immune system and improving cardiovascular health. It lowers cholesterol, aids high blood pressure, and reduces cancer risks. I firmly believe in garlic’s healing properties.
Acetyl L Carnitine
9.5
Beat cancer effectively
Most Useful Review
I have been taking this supplement for years, and I swear by it. I also overcame stage 4 cancer.
8
Increased energy
Most Useful Review
This is my second review. I took one pill every day before work and feel more energetic and capable of various activities. The fatigue I experienced after activities has decreased, and I intend to keep taking it and remain active.
Ginkgo Biloba
8.8
Reduces cancer spread
Most Useful Review
Ginkgo extract promotes blood vessel expansion, lowers blood pressure, and reduces stroke risk. It decreases thrombosis risk, lowers cholesterol, and prevents age-related brain changes. The extract inhibits cancer metastasis while improving brain function and memory, essential for large city dwellers. I am purchasing it for the first time and anticipate positive results from its benefits. The packaging is attractive and should last long enough for thorough evaluation.
8.8
Encourages vascular health
Most Useful Review
Ginkgo extract is recognised for stimulating blood vessel expansion and reducing blood pressure and stroke risks. It lowers the chances of thrombosis and cholesterol levels while preventing age-related brain changes. The extract also suppresses cancer metastases. With long-term use, it can enhance glucose absorption and coordination, combats sleep disorders, and stimulates mental activity, improving memory in older adults. It is beneficial for a wide range of age-related health issues and cognitive impairments.
Zinc
8
Zinc's role in cancer immunity
Implanted Microneedles Loaded with Sparfloxacin and Zinc-Manganese Sulfide Nanoparticles Activates Immunity for Postoperative Triple-Negative Breast Cancer to Prevent Recurrence and Metastasis.
Most Relevant Research
We investigated the impact of zinc, specifically when combined with manganese sulfide, on preventing the recurrence of triple-negative breast cancer (TNBC) post-surgery. This approach involved microneedles loaded with Sparfloxacin and zinc-manganese sulfide, which were targeted for localized treatment to enhance immune response while also addressing wound infection risk.
Through this innovative design, we observed that the zinc-manganese formulation not only displayed strong antimicrobial and antibiofilm properties but also played a role in promoting immune activation. This led to significant reductions in tumor growth and lung metastasis, alongside improved wound healing. The therapy activated key immune pathways, particularly the cGAS-STING pathway, which further bolstered the body’s ability to fight cancer cells.
Overall, the results suggest that zinc, paired with manganese, can provide an effective strategy for enhancing both local and systemic immune responses. This has promising implications for preventing cancer recurrence, particularly in challenging cases like TNBC, paving the way for potential new treatment approaches in oncology.
Through this innovative design, we observed that the zinc-manganese formulation not only displayed strong antimicrobial and antibiofilm properties but also played a role in promoting immune activation. This led to significant reductions in tumor growth and lung metastasis, alongside improved wound healing. The therapy activated key immune pathways, particularly the cGAS-STING pathway, which further bolstered the body’s ability to fight cancer cells.
Overall, the results suggest that zinc, paired with manganese, can provide an effective strategy for enhancing both local and systemic immune responses. This has promising implications for preventing cancer recurrence, particularly in challenging cases like TNBC, paving the way for potential new treatment approaches in oncology.
9.5
Reduces cancer risk
Most Useful Review
Zinc effectively stimulates the immune system and shortens the duration of colds. It aids vision and reduces the risk of age-related macular degeneration. As an antioxidant, zinc plays a vital role in reducing oxidative stress and therefore lowers cancer risk.
Folic Acid
9
Folate receptor targeting in cancer
Mirvetuximab Soravtansine Induces Potent Cytotoxicity and Bystander Effect in Cisplatin-Resistant Germ Cell Tumor Cells.
Most Relevant Research
We explored how the folate receptor alpha (FRα) can be a promising target in treating resistant germ cell tumors (GCTs), which often have poor outcomes due to limited therapeutic options. Our research centered on mirvetuximab soravtansine (MIRV), an antibody-drug conjugate that specifically targets FRα, which is frequently overexpressed in many cancer types, including GCTs.
Through our experiments, we observed that FRα levels were significantly higher in several GCT cell lines as compared to normal tissue. When we treated cisplatin-resistant GCT cells with MIRV, we found it not only triggered cell death but also had a strong effect on unintended bystander cells in direct coculture experiments. This suggests that the treatment may extend its reach beyond just the targeted cancer cells.
Additionally, we confirmed through immunohistochemistry that FRα protein expression is notably elevated in GCT patients after chemotherapy, especially in those with unfavorable prognoses. Our findings emphasize the need for further exploration of FRα-targeting therapies as a potential treatment option for GCTs, particularly those that do not respond well to current therapies. MIRV shows significant antitumor effects and encourages further studies into its use in battling treatment-resistant GCTs.
Through our experiments, we observed that FRα levels were significantly higher in several GCT cell lines as compared to normal tissue. When we treated cisplatin-resistant GCT cells with MIRV, we found it not only triggered cell death but also had a strong effect on unintended bystander cells in direct coculture experiments. This suggests that the treatment may extend its reach beyond just the targeted cancer cells.
Additionally, we confirmed through immunohistochemistry that FRα protein expression is notably elevated in GCT patients after chemotherapy, especially in those with unfavorable prognoses. Our findings emphasize the need for further exploration of FRα-targeting therapies as a potential treatment option for GCTs, particularly those that do not respond well to current therapies. MIRV shows significant antitumor effects and encourages further studies into its use in battling treatment-resistant GCTs.
9.5
Has anticancer properties
Most Useful Review
Methylfolate, the active form of folic acid, crosses the blood-brain barrier to promote a healthy nervous system. It supports cardiovascular health by managing homocysteine levels, which are linked to heart disease. Methylfolate aids in the production of essential neurotransmitters and improves mood. It positively affects cognitive functions and has been shown to have anticancer effects against various tumours, including cervical and colorectal cancers.
Lutein
9.5
Cancer management
Most Useful Review
Since starting on OptiRoute Lutein, I have experienced a significant change, particularly regarding my long-standing battle with Anguard Cancer. For 19 years, I faced numerous challenges, but taking Optimus Lutein seemed to provide a sense of improvement in my overall condition.
9.5
Colon cancer findings
Most Useful Review
Since I started taking it for my eyes, I've noticed a significant improvement. Research from the American Cancer Society indicated that individuals consuming high-lutein diets—found in vegetables like broccoli and spinach—have reported fewer cases of colon cancer. This connection reassures me of the supplement's potential benefits beyond ocular health.
Astaxanthin
8
Helps skin health
Most Useful Review
Astaxanthin improves blood flow, reduces oxidative stress in smokers and overweight individuals, and may assist in the treatment of various forms of cancer. It is no surprise that red is considered beautiful; this compound not only makes flamingos striking but also has a remarkable effect on human skin health.
8.8
Supports recovery post-surgery
Most Useful Review
I have been consistently taking astaxanthin after my cancer surgery, recommended by my doctor for its benefits. It has been two years since my operation, and I'm currently under regular observation, yet I feel healthy. Astaxanthin supplements are hard to find in stores, and it’s difficult to get enough from food, making this supplement very helpful for my recovery.
Pumpkin Seeds Pepitas
9
METTL14 modifications impact AML
Specific sDMA modifications on the RGG/RG motif of METTL14 regulate its function in AML.
Most Relevant Research
We explored how specific changes to the METTL14 protein affect cancer, particularly in acute myeloid leukemia (AML). By examining the RG-rich region of METTL14, we discovered that a special form of arginine methylation called symmetric dimethylation, specifically at positions R425 and R445, plays a vital role in enhancing its function.
Our research revealed that this modification not only improves the activity of the METTL3:METTL14 complex but also influences which genes get expressed in cancer cells. We found that the presence of symmetric dimethylarginines helps the complex deposit a crucial chemical mark, known as m6A, on RNA, which is essential for the regulation of gene activity.
Furthermore, we conducted a series of experiments that indicated a potential therapeutic angle in targeting the METTL3 and PRMT5 proteins. When both are inhibited, we observed a significant drop in the expression of genes important for AML cell growth, hinting at new possibilities for treating this challenging cancer. Overall, this study highlights the intricate relationship between protein modifications and cancer biology, emphasizing the potential for more targeted approaches in therapy.
Our research revealed that this modification not only improves the activity of the METTL3:METTL14 complex but also influences which genes get expressed in cancer cells. We found that the presence of symmetric dimethylarginines helps the complex deposit a crucial chemical mark, known as m6A, on RNA, which is essential for the regulation of gene activity.
Furthermore, we conducted a series of experiments that indicated a potential therapeutic angle in targeting the METTL3 and PRMT5 proteins. When both are inhibited, we observed a significant drop in the expression of genes important for AML cell growth, hinting at new possibilities for treating this challenging cancer. Overall, this study highlights the intricate relationship between protein modifications and cancer biology, emphasizing the potential for more targeted approaches in therapy.
8.8
Supports cancer treatment
Most Useful Review
I ordered pumpkin seeds for the first time and found them to be of excellent quality. They are small, clean, and loved by my children. I give them daily due to their beneficial composition, which includes high protein and healthy fats. Regular consumption is believed to help combat cancer, boost immunity, and improve overall health without side effects. Additionally, they may assist with various ailments and are rich in essential vitamins and minerals. I really enjoyed them and will definitely repurchase.
Probiotics
7
Engineered probiotics target tumor metabolism
Natural Enzyme-Loaded Polymeric Stealth Coating-Armed Engineered Probiotics by Disrupting Tumor Lactate Homeostasis to Synergistic Metabolism-Immuno-Enzyme Dynamic Therapy.
Most Relevant Research
We explored the potential of engineered Lactobacillus acidophilus (LA) as a new method to manage tumor lactate levels and improve cancer treatment. The study developed a special coating for LA to help it avoid being attacked by the immune system while delivering enzymes that reduce L-lactate in tumors.
By doing so, we observed a reduction in the immunosuppressive environment, which can help boost the effectiveness of cancer therapies. Moreover, this engineered probiotic not only delivers enzymes but also converts certain immune cells to better fight tumors. However, the overall effectiveness of this approach appears to require more research to assess its viability in cancer treatment.
By doing so, we observed a reduction in the immunosuppressive environment, which can help boost the effectiveness of cancer therapies. Moreover, this engineered probiotic not only delivers enzymes but also converts certain immune cells to better fight tumors. However, the overall effectiveness of this approach appears to require more research to assess its viability in cancer treatment.
8.8
Reduced tumor growth
Most Useful Review
Excellent product. If used correctly, Lactobacillus acidophilus makes a great contribution to the human body, particularly on three fronts: increasing antimicrobial activity, strengthening the intestinal barrier, and stimulating the immune system. The immunological benefits are significant; L. acidophilus can modulate the immune response by enhancing lymphocyte proliferation. This leads to reduced tumour growth, the inhibition of bacterial cancer enzymes, and lower production of the cytokine that shields tumours from immune surveillance.
Ip6
7
Innovative nanozyme for colon cancer
A multifunctional metal-based nanozyme for CT/PTI-guided photothermal/starvation/chemodynamic therapy against colon tumor.
Most Relevant Research
This study introduced a novel nanozyme, CeO@Au@IP6, designed to tackle colon cancer diagnosis and treatment. We observed that IP6 helps inhibit cancer cell growth while enhancing the nanozyme's stability. The combination of unique properties from cerium dioxide and gold nanoparticles allows for various therapies, including photothermal and chemodynamic therapy. This innovative approach aims to improve early detection and treatment options for colon cancer, ultimately offering new hope for better cure rates.
8.8
Effective for animals
Most Useful Review
Cell Forte Max3 has worked wonders for animals with cancer. I’ve seen it help my hedgehog with liver cancer and a friend’s horse with skin cancer. It also aided my dog with autoimmune issues. After one month, a fatty tumour I had shrank by half. This product is exceedingly safe, and I’ve been a fan since 1990.
Grapeseed
8
Immune support offered
Most Useful Review
NOW Foods Grape Seed Oil provides protection against cell damage caused by free radicals. The antioxidants within help shield cells from detrimental effects that may lead to various diseases, including cardiovascular diseases and cancer. This oil also strengthens the immune system and lowers the risk of infections.
7.5
Aids in cancer prevention
Most Useful Review
Grape seed oil offers several medical benefits, prominently contributing to cancer prevention. It also helps reduce diabetes severity and aids in weight management. Furthermore, it promotes overall heart and kidney health.
Lactobacillus
5
Gut bacteria influence chemotherapy outcomes
Metagenome association study of the gut microbiome revealed biomarkers linked to chemotherapy outcomes in locally advanced and advanced lung cancer.
Most Relevant Research
We explored the connection between gut bacteria and chemotherapy outcomes in lung cancer patients. By studying stool samples from 64 individuals with locally advanced and advanced lung cancer, we compared the gut microbiota of those who responded to treatment with those who did not.
Notably, certain bacteria, like Streptococcus mutans, were more abundant in responders, while Leuconostoc lactis was associated with nonresponders. This suggests that the makeup of our gut microbiome may influence how well chemotherapy works in these patients, offering insights for more personalized treatment strategies.
Notably, certain bacteria, like Streptococcus mutans, were more abundant in responders, while Leuconostoc lactis was associated with nonresponders. This suggests that the makeup of our gut microbiome may influence how well chemotherapy works in these patients, offering insights for more personalized treatment strategies.
8.8
Improved intestinal health
Most Useful Review
I am pleasantly surprised. After taking 2 or 3 tablets daily for ten days, I noticed positive changes. My usual morning stool now comes out around 2 pm. Previously, I experienced painful bloating after lunch, but that discomfort has disappeared, and my bowel movements are much smoother. After my mother died of colon cancer, I feared inheriting that issue, so I started this to improve my gut health. I look forward to continuing this and hope it will benefit both my intestinal and skin health over the next three months.
L Glutamine
8
Efficacy of L-glutaminase in cancer
L-glutaminase synthesis by Klebsiella pneumoniae (AS KP 23) isolated from clinical strain, and its efficacy against human hepatocellular and breast cancer cell lines.
Most Relevant Research
We explored the effects of L-glutaminase, produced by Klebsiella pneumoniae AS KP 23, on cancer cells. This enzyme is noteworthy because cancer cells often rely heavily on glutamine to grow and survive. By targeting and breaking down glutamine, L-glutaminase serves as a promising approach to inhibit cancer cell proliferation.
Our study demonstrated that purified L-glutaminase not only impacted normal cells but also showed significant anticancer activity against various cancer cell lines. Specifically, we found that this enzyme effectively reduced the growth of hepatocellular and breast cancer cells. Its stability across different pH levels and temperatures enhances its potential as a viable treatment option.
With previous research highlighting the importance of glutamine in cancer metabolism, the activation of L-glutaminase presents a compelling strategy for cancer therapy. This reinforces the potential of L-glutaminase as an alternative to traditional chemotherapy, providing a new avenue for the development of cancer treatments that might improve patient outcomes.
Our study demonstrated that purified L-glutaminase not only impacted normal cells but also showed significant anticancer activity against various cancer cell lines. Specifically, we found that this enzyme effectively reduced the growth of hepatocellular and breast cancer cells. Its stability across different pH levels and temperatures enhances its potential as a viable treatment option.
With previous research highlighting the importance of glutamine in cancer metabolism, the activation of L-glutaminase presents a compelling strategy for cancer therapy. This reinforces the potential of L-glutaminase as an alternative to traditional chemotherapy, providing a new avenue for the development of cancer treatments that might improve patient outcomes.
9.5
Increased energy
Most Useful Review
I bought it for my mum, a breast cancer survivor, and this supplement provides her with more energy. It’s a fantastic product.
Vitamin E
8
Gamma-tocopherol in cancer research
Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties.
Most Relevant Research
We examined the effects of gamma-tocopherol, a major form of vitamin E, on cancer treatment and prevention. This powerful antioxidant is noted for its ability to combat oxidative stress, which plays a significant role in the development and progression of various cancers.
In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow.
Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management.
While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness.
In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow.
Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management.
While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness.
9.5
Prevents cancer development
Most Useful Review
Tocotrienols enhance the cardiovascular system and brain activity; they prevent cancer cell development and trigger their self-destruction. Their potent antioxidant action safeguards nerve cells from disease, offers a remarkable rejuvenating effect, and wards off diabetes.
Beta Glucan
8
Cancer-targeting yeast technology
Lysosome-Targeting Chimera Using Mannose-6-Phosphate Glycans Derived from Glyco-Engineered Yeast.
Most Relevant Research
We explored a new treatment mechanism using a formulation called LYTAC that employs glyco-engineered yeast-derived glycans for targeting cancer cells. This method taps into the body’s natural lysosomal degradation system to remove a protein linked to tumors.
In our study, LYTAC demonstrated the ability to effectively degrade the PD-L1 protein, which is known to inhibit T cell activity against cancer. Not only did it show greater effectiveness compared to traditional treatments, but it also highlights an innovative approach that could play a vital role in advancing cancer therapies.
In our study, LYTAC demonstrated the ability to effectively degrade the PD-L1 protein, which is known to inhibit T cell activity against cancer. Not only did it show greater effectiveness compared to traditional treatments, but it also highlights an innovative approach that could play a vital role in advancing cancer therapies.
8.8
Effective support
Most Useful Review
Helps me for a long time in the fight against cancer. I discovered this product through my doctor after a detailed immune analysis showed deficiencies. As I'm undergoing chemotherapy, I need to support my body. Since I began taking this in 2018, I’ve seen results: stomatitis and dermatophytosis have disappeared. Most importantly, there is some stability in my underlying disease (sarcoma). Last year, I paused the medication, and in three months, I noticed a negative trend. Ultimately, I've decided to continue this medication for my lifetime as I can clearly see the benefits!
Ashwagandha
7
DHA's potential in cancer therapy
DTX2 attenuates Lenvatinib-induced ferroptosis by suppressing docosahexaenoic acid biosynthesis through HSD17B4-dependent peroxisomal β-oxidation in hepatocellular carcinoma.
Most Relevant Research
In our exploration of liver cancer treatment, we found that combinations of Lenvatinib—an established first-line therapy—and docosahexaenoic acid (DHA) can uniquely influence outcomes. The focus was on understanding how Lenvatinib resistance develops in hepatocellular carcinoma (HCC) and the potential role of DHA in this context.
Through comprehensive studies, including CRISPR screening in liver cancer cells, we discovered that a protein called DTX2 strongly contributes to Lenvatinib resistance. This protein helps protect the cancer cells from a type of cell death known as ferroptosis, which Lenvatinib usually triggers. Interestingly, we learned that DTX2 does this by reducing DHA levels, a fatty acid that plays a crucial role in cellular health.
In our findings, when we added DHA to Lenvatinib treatment, it appeared to counteract DTX2's protective effect against ferroptosis. The study emphasized that using DHA in combination with Lenvatinib could potentially offer a new therapeutic pathway for patients facing drug resistance in liver cancer.
Overall, the relationship between DTX2, DHA production, and Lenvatinib resistance presents an exciting avenue for further exploration in cancer treatment strategies.
Through comprehensive studies, including CRISPR screening in liver cancer cells, we discovered that a protein called DTX2 strongly contributes to Lenvatinib resistance. This protein helps protect the cancer cells from a type of cell death known as ferroptosis, which Lenvatinib usually triggers. Interestingly, we learned that DTX2 does this by reducing DHA levels, a fatty acid that plays a crucial role in cellular health.
In our findings, when we added DHA to Lenvatinib treatment, it appeared to counteract DTX2's protective effect against ferroptosis. The study emphasized that using DHA in combination with Lenvatinib could potentially offer a new therapeutic pathway for patients facing drug resistance in liver cancer.
Overall, the relationship between DTX2, DHA production, and Lenvatinib resistance presents an exciting avenue for further exploration in cancer treatment strategies.
9.5
Aid during treatment
Most Useful Review
This brand helped significantly during my battle with cancer. After years of consistent use, I believe the quality remains high. The caplets may have a strong odour, but with water, I manage to take them without any issues.
N Acetyl Cysteine Nac
8
Cancer-targeting yeast technology
Lysosome-Targeting Chimera Using Mannose-6-Phosphate Glycans Derived from Glyco-Engineered Yeast.
Most Relevant Research
We explored a new treatment mechanism using a formulation called LYTAC that employs glyco-engineered yeast-derived glycans for targeting cancer cells. This method taps into the body’s natural lysosomal degradation system to remove a protein linked to tumors.
In our study, LYTAC demonstrated the ability to effectively degrade the PD-L1 protein, which is known to inhibit T cell activity against cancer. Not only did it show greater effectiveness compared to traditional treatments, but it also highlights an innovative approach that could play a vital role in advancing cancer therapies.
In our study, LYTAC demonstrated the ability to effectively degrade the PD-L1 protein, which is known to inhibit T cell activity against cancer. Not only did it show greater effectiveness compared to traditional treatments, but it also highlights an innovative approach that could play a vital role in advancing cancer therapies.
10
Cancer prevention
Most Useful Review
Great product! I had stage 4 cancer, and this supplement is essential for helping me stay cancer-free!
Ubiquinol Coq10
8
Ubiquinol aids radiation gut health
Gastroprotective and microbiome-modulating effects of ubiquinol in rats with radiation-induced enteropathy.
Most Relevant Research
In a fascinating exploration of how ubiquinol may aid in managing cancer-related issues, we investigated its effects on radiation-induced enteropathy—a condition that can severely impact patients undergoing radiotherapy. Using a well-structured study design, we divided male albino rats into four groups: one that received only radiation, and three others that received varying treatments with ubiquinol either before or after exposure to radiation.
Our findings revealed that the rats treated with ubiquinol showed marked improvements in gut health when compared to those that only experienced radiation. We saw indications of enhanced healing in their intestinal tissues, including the recovery of important cells and reduced inflammation markers. Notably, the gut microbiomes of the ubiquinol-treated groups began to resemble those of healthy control rats, indicating that this treatment may help restore balance to the gut flora disrupted by radiation.
This research highlights the potential of ubiquinol not only to protect the gut from radiation damage but also to support overall health in cancer patients by aiding in the recovery of gut microbiota diversity. It seems that ubiquinol could indeed play a significant role in enhancing the quality of life for individuals undergoing cancer treatments, particularly those affected by gastrointestinal side effects.
Our findings revealed that the rats treated with ubiquinol showed marked improvements in gut health when compared to those that only experienced radiation. We saw indications of enhanced healing in their intestinal tissues, including the recovery of important cells and reduced inflammation markers. Notably, the gut microbiomes of the ubiquinol-treated groups began to resemble those of healthy control rats, indicating that this treatment may help restore balance to the gut flora disrupted by radiation.
This research highlights the potential of ubiquinol not only to protect the gut from radiation damage but also to support overall health in cancer patients by aiding in the recovery of gut microbiota diversity. It seems that ubiquinol could indeed play a significant role in enhancing the quality of life for individuals undergoing cancer treatments, particularly those affected by gastrointestinal side effects.
8.8
Prevents disease progression
Most Useful Review
Excellent ubiquinol. It is the reduced form of Coenzyme Q10, meaning it is absorbed more efficiently. This potent antioxidant is often lacking in our diets, especially after 30, leading to quicker skin aging and potentially diminishing organ and cognitive function. Ubiquinol is crucial for countering free radicals, which can cause cellular dysfunction and elevate cancer risk. Sufficient intake can avert various diseases, from cancer to Alzheimer's. Ubiquinol has also proven effective in treating COVID-19 and its aftermath. I highly recommend it for regular use and therapeutic purposes!
Efa Omega 3 6 9 Combinations
9
METTL14 modifications impact AML
Specific sDMA modifications on the RGG/RG motif of METTL14 regulate its function in AML.
Most Relevant Research
We explored how specific changes to the METTL14 protein affect cancer, particularly in acute myeloid leukemia (AML). By examining the RG-rich region of METTL14, we discovered that a special form of arginine methylation called symmetric dimethylation, specifically at positions R425 and R445, plays a vital role in enhancing its function.
Our research revealed that this modification not only improves the activity of the METTL3:METTL14 complex but also influences which genes get expressed in cancer cells. We found that the presence of symmetric dimethylarginines helps the complex deposit a crucial chemical mark, known as m6A, on RNA, which is essential for the regulation of gene activity.
Furthermore, we conducted a series of experiments that indicated a potential therapeutic angle in targeting the METTL3 and PRMT5 proteins. When both are inhibited, we observed a significant drop in the expression of genes important for AML cell growth, hinting at new possibilities for treating this challenging cancer. Overall, this study highlights the intricate relationship between protein modifications and cancer biology, emphasizing the potential for more targeted approaches in therapy.
Our research revealed that this modification not only improves the activity of the METTL3:METTL14 complex but also influences which genes get expressed in cancer cells. We found that the presence of symmetric dimethylarginines helps the complex deposit a crucial chemical mark, known as m6A, on RNA, which is essential for the regulation of gene activity.
Furthermore, we conducted a series of experiments that indicated a potential therapeutic angle in targeting the METTL3 and PRMT5 proteins. When both are inhibited, we observed a significant drop in the expression of genes important for AML cell growth, hinting at new possibilities for treating this challenging cancer. Overall, this study highlights the intricate relationship between protein modifications and cancer biology, emphasizing the potential for more targeted approaches in therapy.
8.8
Skin cancer prevention
Most Useful Review
The yellow colour of the oil may appear darker than others. Its texture is rather heavy, and while the quality is satisfactory, the smell resembles oatmeal and lingers. Despite this, its benefits outweigh the drawbacks, as it accelerates healing for skin wounds and burns, reduces scar appearance, alleviates itching, and helps prevent skin cancer. Additionally, it can lighten skin tone and address hair breakage and stretch marks. Being a larger package, it's advisable to use it in mixtures for hair or skin, as it should be diluted for effective use. If my comment helps, please give a like 💗
Calcium
7
Calcium treatment impacts cancer viability
Investigation of the Bystander Effect on Cell Viability After Application of Combined Electroporation-Based Methods.
Most Relevant Research
We investigated how calcium treatment, in conjunction with various electroporation methods, affects cancer cell viability. In our study, we used 4T1 breast cancer cells and applied different forms of electroporation, such as reversible and irreversible treatments along with calcium electroporation. We were particularly interested in the bystander effect, where treated cells might affect untreated nearby cells.
By transferring conditioned media from the treated to untreated cells, we observed significant impacts on cell viability. The results showed that after applying calcium electroporation and bleomycin treatments, colony formation plummeted to nearly zero, and metabolic activity dipped as low as 11.62%. Additionally, other assessments, including flow cytometry, confirmed a drastic decrease in cell viability in the presence of calcium therapy.
While the study highlighted calcium’s role in enhancing the effects of electroporation, the combined treatments reduced the overall viability of surrounding cells markedly. We also noticed a delay in wound healing with conditioned media, indicating that calcium treatment could significantly impact not just treated but also neighboring cancer cells. Overall, calcium's combined effects were powerful, emphasizing its utility in cancer treatment strategies.
By transferring conditioned media from the treated to untreated cells, we observed significant impacts on cell viability. The results showed that after applying calcium electroporation and bleomycin treatments, colony formation plummeted to nearly zero, and metabolic activity dipped as low as 11.62%. Additionally, other assessments, including flow cytometry, confirmed a drastic decrease in cell viability in the presence of calcium therapy.
While the study highlighted calcium’s role in enhancing the effects of electroporation, the combined treatments reduced the overall viability of surrounding cells markedly. We also noticed a delay in wound healing with conditioned media, indicating that calcium treatment could significantly impact not just treated but also neighboring cancer cells. Overall, calcium's combined effects were powerful, emphasizing its utility in cancer treatment strategies.
8.8
Cancer prevention support
Most Useful Review
Calcium and magnesium, along with zinc, are essential for immune support, bones, and overall health. These elements are vital for bone, teeth, and muscle tone health. Zinc bolsters immune functions, aids in healing, and is crucial for the prostate and reproductive systems. The combination with Vitamin D3 enhances calcium absorption. However, I find taking these tablets three times daily rather inconvenient. The blend plays an essential role in cancer prevention.
Barley Grass
9.5
Improved health
Most Useful Review
You are the best! Thank you for your products! They have greatly assisted my mum with her cancer! She is now in good health.
7.8
Health care effects
Most Useful Review
Barley seedling powder is abundant in chlorophyll, antioxidant enzymes, and various nutrients. Medical research confirms its health benefits, particularly in anti-cancer effects, liver protection, and enhancing cell vitality. Consequently, it holds a significant role in health foods. Research shows chlorophyll effectively reduces carcinogenic toxicity more than vitamin C, vitamin E, or beta-carotene.
Calcium Magnesium
7
Calcium treatment impacts cancer viability
Investigation of the Bystander Effect on Cell Viability After Application of Combined Electroporation-Based Methods.
Most Relevant Research
We investigated how calcium treatment, in conjunction with various electroporation methods, affects cancer cell viability. In our study, we used 4T1 breast cancer cells and applied different forms of electroporation, such as reversible and irreversible treatments along with calcium electroporation. We were particularly interested in the bystander effect, where treated cells might affect untreated nearby cells.
By transferring conditioned media from the treated to untreated cells, we observed significant impacts on cell viability. The results showed that after applying calcium electroporation and bleomycin treatments, colony formation plummeted to nearly zero, and metabolic activity dipped as low as 11.62%. Additionally, other assessments, including flow cytometry, confirmed a drastic decrease in cell viability in the presence of calcium therapy.
While the study highlighted calcium’s role in enhancing the effects of electroporation, the combined treatments reduced the overall viability of surrounding cells markedly. We also noticed a delay in wound healing with conditioned media, indicating that calcium treatment could significantly impact not just treated but also neighboring cancer cells. Overall, calcium's combined effects were powerful, emphasizing its utility in cancer treatment strategies.
By transferring conditioned media from the treated to untreated cells, we observed significant impacts on cell viability. The results showed that after applying calcium electroporation and bleomycin treatments, colony formation plummeted to nearly zero, and metabolic activity dipped as low as 11.62%. Additionally, other assessments, including flow cytometry, confirmed a drastic decrease in cell viability in the presence of calcium therapy.
While the study highlighted calcium’s role in enhancing the effects of electroporation, the combined treatments reduced the overall viability of surrounding cells markedly. We also noticed a delay in wound healing with conditioned media, indicating that calcium treatment could significantly impact not just treated but also neighboring cancer cells. Overall, calcium's combined effects were powerful, emphasizing its utility in cancer treatment strategies.
8.8
Normal health indicators
Most Useful Review
For a friend, 60+ After cancer, a woman constantly takes some medications, the side effect of which is a decrease in bone density. The doctor recommended taking calcium in addition, along with magnesium and vitamin D3+K2 for better absorption. On control examinations, all her indicators are normal, as well as her well-being. ❤️
Vitamin D
8
Vitamin D analogs in prostate cancer
[New insights of vitamin D-based therapy for prostate cancer].
Most Relevant Research
We explored the potential benefits of a vitamin D analog in treating prostate cancer, which is a major cause of cancer-related deaths among men. Our work focused on understanding how this vitamin D form impacts cancer resistance and the tumor microenvironment. We used the Pten mouse model to observe the therapeutic effects of the vitamin D analog.
One significant finding was that combining this vitamin D analog with the chemotherapy drug docetaxel could overcome resistance seen in some prostate cancer cases. This combination showed promising results in primary cancer spheroids and xenografts from a patient whose cancer had resisted both docetaxel and androgen deprivation therapy.
These insights suggest that vitamin D analogs might offer new and effective strategies for managing advanced prostate cancer, particularly for those patients who have not responded well to standard treatments.
One significant finding was that combining this vitamin D analog with the chemotherapy drug docetaxel could overcome resistance seen in some prostate cancer cases. This combination showed promising results in primary cancer spheroids and xenografts from a patient whose cancer had resisted both docetaxel and androgen deprivation therapy.
These insights suggest that vitamin D analogs might offer new and effective strategies for managing advanced prostate cancer, particularly for those patients who have not responded well to standard treatments.
8.8
Supports cancer treatment
Most Useful Review
Vitamine D is crucial for bone health and has anti-cancer benefits. If your 25 (OH) D level is 20 or less, it's advisable to start with 5000 IU daily. For levels 21-30, take 2,000 IU, and if it's 31-40, take 1000 IU daily. After three months, retest. The optimal level is 50-70. Vitamin D supplementation raises levels effectively without odour. Sunlight aids production, but sunscreen can hinder it. This supplement has improved my health significantly. Happy shopping!
Vitamin A
4
RAR-β deletion alters pancreatic cancer
Retinoic acid receptor-β deletion in a model of early pancreatic ductal adenocarcinoma (PDAC) tumorigenesis.
Most Relevant Research
We examined how the deletion of the retinoic acid receptor beta (RAR-β) impacts cancer development in the pancreas. Using a specific mouse model designed for this study, we selectively knocked out the RAR-β gene to see how this would affect pancreatic cells and their behavior in relation to cancer.
Our findings revealed that a lack of RAR-β led to decreased cell proliferation in the pancreatic acinar cells. In simpler terms, without this receptor, the cells were less likely to multiply, which is significant because uncontrolled cell growth is a hallmark of cancer. Interestingly, even in the absence of an activation mutation in the KRas gene, levels of SOX9—a protein vital for pancreatic cancer formation and maintenance—increased in the knockout models.
This suggests that while RAR-β deletion seems to inhibit cell growth, it paradoxically raises SOX9 levels, which could play a complex role in cancer progression. Ultimately, we uncovered that retinoic acid signaling, particularly through RAR-β, may have a nuanced influence on pancreatic cancer development, but we did not directly assess the effects of vitamin A treatments themselves nor did we find universally beneficial effects in this model.
Our findings revealed that a lack of RAR-β led to decreased cell proliferation in the pancreatic acinar cells. In simpler terms, without this receptor, the cells were less likely to multiply, which is significant because uncontrolled cell growth is a hallmark of cancer. Interestingly, even in the absence of an activation mutation in the KRas gene, levels of SOX9—a protein vital for pancreatic cancer formation and maintenance—increased in the knockout models.
This suggests that while RAR-β deletion seems to inhibit cell growth, it paradoxically raises SOX9 levels, which could play a complex role in cancer progression. Ultimately, we uncovered that retinoic acid signaling, particularly through RAR-β, may have a nuanced influence on pancreatic cancer development, but we did not directly assess the effects of vitamin A treatments themselves nor did we find universally beneficial effects in this model.
9.5
Improved gastritis
Most Useful Review
The required amount of Vitamin A varies significantly depending on individual circumstances. Those with dry eye, asthma, gastrointestinal issues, or a family history of cancer may require more. I gradually increased my intake to 100,000 units for a year, which cleared my persistent red sore gastritis, eliminating the need for medication.
Vitamin K
7
Vitamin K2 supports bone health
Suppressive effect of vitamin K (menatetrenone) against bone mineral density loss after radiotherapy in uterine cancer patients.
Most Relevant Research
We explored whether vitamin K2, specifically menatetrenone, can help prevent the loss of bone mineral density (BMD) in patients with uterine cancer after they underwent radiotherapy. Our study included 34 patients who received whole pelvic irradiation, divided into two groups: one that took vitamin K2 for at least a year and a control group that did not.
We measured BMD at various intervals—before treatment, immediately after, and at 3, 6, and 12 months post-radiotherapy. While we found no remarkable changes in BMD at L3-L4, which was outside the irradiated area, we did see significant reductions in BMD at L5-S1, within the irradiated field, for those in the control group who did not receive vitamin K2. Conversely, patients taking vitamin K2 displayed a more stable BMD, suggesting that it may help mitigate some of the adverse effects of radiotherapy.
Our findings included some complications, such as insufficiency fractures, but they were evenly distributed across both groups. This indicates that while vitamin K2 may not directly attack the cancer, it shows promise in preserving bone health during and after treatment, which is crucial for improving the patient's overall quality of life. More extensive studies are needed to confirm these results.
We measured BMD at various intervals—before treatment, immediately after, and at 3, 6, and 12 months post-radiotherapy. While we found no remarkable changes in BMD at L3-L4, which was outside the irradiated area, we did see significant reductions in BMD at L5-S1, within the irradiated field, for those in the control group who did not receive vitamin K2. Conversely, patients taking vitamin K2 displayed a more stable BMD, suggesting that it may help mitigate some of the adverse effects of radiotherapy.
Our findings included some complications, such as insufficiency fractures, but they were evenly distributed across both groups. This indicates that while vitamin K2 may not directly attack the cancer, it shows promise in preserving bone health during and after treatment, which is crucial for improving the patient's overall quality of life. More extensive studies are needed to confirm these results.
8.8
Antitumour properties
Most Useful Review
Vitamin K2 is vital for calcium absorption and blood clotting. It redirects calcium from the blood to bone tissue, which is crucial for bone and dental health. Notably, in 2006, its antitumour properties were discovered, showing benefits against certain cancers, including lung, pancreatic, bladder, and rectal. Ongoing studies continue to explore its potential.
L Taurine
8
Taurine's protective role in cancer
Interplay of serum taurine, S-adenosylmethionine, and cysteine levels in cancer risk: a prospective study.
Most Relevant Research
We conducted a nested case-control study within a large cohort to understand how levels of taurine, S-adenosylmethionine (SAM), and cysteine in our blood are related to cancer risk, particularly among Chinese adults. Our analysis included 1,391 cancer cases matched with 1,391 controls, providing a robust framework for our findings.
Our results showed that higher levels of taurine in the blood could reduce overall cancer risk, particularly for digestive cancers. This is an exciting discovery as it suggests that taurine might play a protective role. On the contrary, elevated levels of SAM appeared linked to an increased risk of digestive cancers.
Using advanced statistical models, we identified complex interactions among taurine, SAM, and cysteine. Notably, we observed a significant overall negative association between the combination of these amino acids and cancer risk, highlighting the intricate balance these compounds maintain in our metabolism.
Overall, while taurine seems to confer some protective benefits, the specific metabolic relationships and their implications for treatment and prevention strategies need further exploration. Our findings could pave the way for new approaches in cancer prevention.
Our results showed that higher levels of taurine in the blood could reduce overall cancer risk, particularly for digestive cancers. This is an exciting discovery as it suggests that taurine might play a protective role. On the contrary, elevated levels of SAM appeared linked to an increased risk of digestive cancers.
Using advanced statistical models, we identified complex interactions among taurine, SAM, and cysteine. Notably, we observed a significant overall negative association between the combination of these amino acids and cancer risk, highlighting the intricate balance these compounds maintain in our metabolism.
Overall, while taurine seems to confer some protective benefits, the specific metabolic relationships and their implications for treatment and prevention strategies need further exploration. Our findings could pave the way for new approaches in cancer prevention.
9.5
Cancer prevention
Most Useful Review
This product prevents the onset of cancer and reduces blood glucose levels. It assists in the formation and restoration of the retina within the eyes after injuries and helps to normalise blood pressure. The quality is exceptional, and the dosage is excellent.
Prebiotic Fiber Inulin
8
Inulin mitigates cancer risk factors
Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer.
Most Relevant Research
We set out to understand how dietary choices and genetics influence the cancer-causing potential of certain bacteria, specifically colibactin-producing E. coli, in a mouse model. By examining mice that were colonized with these bacteria and feeding them various diets, including one that was low in carbohydrates and soluble fiber, we observed some striking results. Mice on the low-carbohydrate diet showed an increase in colonic polyps, which are precursors to cancer.
The study revealed that a lack of soluble fiber led to higher levels of mucosal inflammation, which in turn impaired a key signaling pathway in the colon known as PPAR-γ. This disruption not only boosted the growth of colibactin-producing E. coli but also led to significant DNA damage. However, we discovered that administering inulin, a type of soluble fiber, helped counteract these harmful effects. It reduced inflammation and the number of polyps in the affected mice, highlighting the potential protective quality of inulin.
Additionally, in mice that had deficiencies in DNA mismatch repair, we found that E. coli exacerbated polyp formation through another mechanism involving inflammation. This suggests that dietary fiber, particularly inulin, may play a critical role in preventing inflammation-driven carcinogenesis in the gut. By understanding the interplay between diet, microbiome, and cancer risk, we can better appreciate how something as simple as dietary fiber can help shape our health.
The study revealed that a lack of soluble fiber led to higher levels of mucosal inflammation, which in turn impaired a key signaling pathway in the colon known as PPAR-γ. This disruption not only boosted the growth of colibactin-producing E. coli but also led to significant DNA damage. However, we discovered that administering inulin, a type of soluble fiber, helped counteract these harmful effects. It reduced inflammation and the number of polyps in the affected mice, highlighting the potential protective quality of inulin.
Additionally, in mice that had deficiencies in DNA mismatch repair, we found that E. coli exacerbated polyp formation through another mechanism involving inflammation. This suggests that dietary fiber, particularly inulin, may play a critical role in preventing inflammation-driven carcinogenesis in the gut. By understanding the interplay between diet, microbiome, and cancer risk, we can better appreciate how something as simple as dietary fiber can help shape our health.
8.8
Boosts immune system
Most Useful Review
I chose Inulin over other prebiotics after consulting with my gastroenterologist. It reaches the bowels where beneficial bacteria grow and inhibits certain fats' growth. Inulin serves as a valuable dietary fibre and helps reduce the risk of cancer while enhancing immune functions. If this review has helped you, please give it a thumbs up. Thank you!
Sports Fish Oil Omegas
7
Effects of fatty acids on cancer
Investigation of the Effects of Polyunsaturated Fatty Acid Ratios in Human SH-SY5Y Cells by Methods.
Most Relevant Research
We aimed to understand how different ratios of omega-3 and omega-6 fatty acids, particularly eicosapentaenoic acid (EPA), influence neuroblastoma cells. This type of cancer is known as one of the most aggressive forms affecting children.
During our study, we treated human neuroblastoma cells (SH-SY5Y) with various ratios of omega-3 and omega-6 fatty acids for 48 and 72 hours. To measure the effectiveness of these treatments, we looked at cell viability, levels of oxidative stress, and apoptosis—essentially, did the treatments help kill the cancer cells?
Our findings revealed that while increasing the omega-3 to omega-6 ratio led to lower levels of reactive oxygen species, it also reduced the apoptosis rates in these cells. Although we observed some effects with omega fatty acids, there was no significant evidence supporting the idea that eicosapentaenoic acid alone would provide a strong anticancer benefit.
This research marks an important investigation into how fatty acids interact with cancer cells, although the results indicate that taking omega-3 fatty acids might not be a cure or significant treatment for neuroblastoma on their own.
During our study, we treated human neuroblastoma cells (SH-SY5Y) with various ratios of omega-3 and omega-6 fatty acids for 48 and 72 hours. To measure the effectiveness of these treatments, we looked at cell viability, levels of oxidative stress, and apoptosis—essentially, did the treatments help kill the cancer cells?
Our findings revealed that while increasing the omega-3 to omega-6 ratio led to lower levels of reactive oxygen species, it also reduced the apoptosis rates in these cells. Although we observed some effects with omega fatty acids, there was no significant evidence supporting the idea that eicosapentaenoic acid alone would provide a strong anticancer benefit.
This research marks an important investigation into how fatty acids interact with cancer cells, although the results indicate that taking omega-3 fatty acids might not be a cure or significant treatment for neuroblastoma on their own.
9.5
Essential for family
Most Useful Review
Due to my family's struggles with cancer, I need to take high doses of fish oil, particularly those rich in EPA. Just one fish oil a day is manageable, especially for the elderly, and it is in an easily absorbed Tg form. I highly recommend it.
Lactoferrin
8
Lactoferrin and vanadium complex efficacy
Lactoferrin Nanoparticle-Vanadium Complex: A Promising High-Efficiency Agent against Glioblastoma by Triggering Autophagy and Ferroptosis.
Most Relevant Research
We embarked on a journey to evaluate a novel treatment approach for glioblastoma, one of the most formidable types of brain cancer. Our research focused on creating a delivery system using lactoferrin in combination with vanadium complexes, known as LF-V4 nanoparticles.
This innovative nanoparticle system was designed to cross the blood-brain barrier effectively. It targeted glioblastoma cells, promoting a significant inhibition of tumor growth. We were excited to see that LF-V4 nanoparticles worked by inducing autophagic cell death in cancer cells through the generation of reactive oxygen species (ROS), which led to severe damage to the mitochondria.
Additionally, our findings revealed that these nanoparticles triggered lipid peroxidation. This reaction was fueled by an accumulation of ROS, a depletion of glutathione, and a decrease in specific proteins linked to cellular protection. Ultimately, this chain of events led to ferroptosis, a unique form of cancer cell death that could provide a new avenue for cancer treatments.
Overall, our exploration into lactoferrin's potential for combating glioblastoma demonstrates a promising direction in cancer research. It highlights the effectiveness of using targeted delivery systems to enhance treatment outcomes for patients facing one of the most challenging cancer types.
This innovative nanoparticle system was designed to cross the blood-brain barrier effectively. It targeted glioblastoma cells, promoting a significant inhibition of tumor growth. We were excited to see that LF-V4 nanoparticles worked by inducing autophagic cell death in cancer cells through the generation of reactive oxygen species (ROS), which led to severe damage to the mitochondria.
Additionally, our findings revealed that these nanoparticles triggered lipid peroxidation. This reaction was fueled by an accumulation of ROS, a depletion of glutathione, and a decrease in specific proteins linked to cellular protection. Ultimately, this chain of events led to ferroptosis, a unique form of cancer cell death that could provide a new avenue for cancer treatments.
Overall, our exploration into lactoferrin's potential for combating glioblastoma demonstrates a promising direction in cancer research. It highlights the effectiveness of using targeted delivery systems to enhance treatment outcomes for patients facing one of the most challenging cancer types.
8.8
Breast cancer growth
Most Useful Review
I acquired this supplement for three main reasons: to protect against viruses and fungi, enhance iron absorption, and improve intestinal health. I learned that lactoferrin may inhibit the growth of breast cancer cells. However, I feel one course may not suffice to see significant results. Wishing everyone good health and a positive mindset!
Omega 3 Fish Oil
8
Fatty acids influence esophageal cancer risk
Association between red blood cell fatty acids composition and risk of esophageal cancer: a hospital-based case-control study.
Most Relevant Research
We assessed how different types of fatty acids in red blood cells relate to the risk of esophageal cancer. Analyzing samples from 158 cancer patients and 224 controls, we found that higher levels of omega-3 fats, like DHA and EPA, were linked to a lower risk of developing this aggressive cancer. Conversely, high concentrations of certain saturated fats were associated with increased risk. Our findings suggest that the balance of fatty acids in the diet may have important implications for esophageal cancer susceptibility.
8.3
Cancer prevention
Most Useful Review
Omega is of high quality, increases immunity, has a pleasant scent, and offers great benefits. I believe it helps prevent cancer and comes in a tightly sealed package. It serves as a strong antioxidant and cleanses the body.
Garlic
7
Garlic's dual effects in cancer
Mechanism of Action and Interaction of Garlic Extract and Established Therapeutics in Prostate Cancer.
Most Relevant Research
We explored the effects of garlic extract (GE) on prostate cancer (PCa) cells to understand how it might work alongside established cancer therapies. A notable case mentioned a patient who managed to maintain stable prostate-specific antigen (PSA) levels for over 14 years with daily GE intake after being diagnosed with PCa, which piqued our curiosity about GE's potential benefits.
In our study, we looked at how GE impacts different prostate cells, including healthy cells and various PCa cell lines. We observed that GE reduced the growth of LNCaP and PC3 cancer cells while showing mixed results with VCaP cells. This indicates that while garlic could slow cancer cell proliferation in some cases, it doesn't work uniformly across all types of cancer cells.
Additionally, we investigated how GE interacts with common cancer treatments like chemotherapy and androgen deprivation therapy. Surprisingly, the combination of GE with these therapies diminished their effectiveness, possibly due to an increase in a specific enzyme in cancer cells that affects drug metabolism. This finding suggests that while GE may offer some anti-cancer properties, its use should be carefully monitored when combined with established cancer treatments to avoid unintended consequences.
In our study, we looked at how GE impacts different prostate cells, including healthy cells and various PCa cell lines. We observed that GE reduced the growth of LNCaP and PC3 cancer cells while showing mixed results with VCaP cells. This indicates that while garlic could slow cancer cell proliferation in some cases, it doesn't work uniformly across all types of cancer cells.
Additionally, we investigated how GE interacts with common cancer treatments like chemotherapy and androgen deprivation therapy. Surprisingly, the combination of GE with these therapies diminished their effectiveness, possibly due to an increase in a specific enzyme in cancer cells that affects drug metabolism. This finding suggests that while GE may offer some anti-cancer properties, its use should be carefully monitored when combined with established cancer treatments to avoid unintended consequences.
9.5
Strengthens immunity
Most Useful Review
Garlic is excellent for the gut, enhancing enzyme secretion and digestion, while strengthening the immune system and improving cardiovascular health. It lowers cholesterol, aids high blood pressure, and reduces cancer risks. I firmly believe in garlic’s healing properties.
Milk Thistle Silymarin
7
Nano-silymarin shows potential benefits
Evaluation of Oral Nano-Silymarin Formulation Efficacy in the Prevention of Hand-Foot Syndrome and Neuropathy Induced by XELOX or m-FOLFOX6 Regimens in Metastatic Colorectal Cancer: A Triple-Blinded, Randomized Clinical Trial.
Most Relevant Research
We conducted a triple-blinded, randomized clinical trial involving 60 patients to explore if nano-silymarin could reduce neuropathy and hand-foot syndrome caused by popular chemotherapy regimens used for metastatic colorectal cancer.
Patients received nano-silymarin during their treatment, and we assessed the severity of any side effects after three and six chemotherapy cycles.
While the study suggests that nano-silymarin might help prevent these adverse reactions, more extensive research is needed to confirm these findings and examine different doses.
Patients received nano-silymarin during their treatment, and we assessed the severity of any side effects after three and six chemotherapy cycles.
While the study suggests that nano-silymarin might help prevent these adverse reactions, more extensive research is needed to confirm these findings and examine different doses.
9.5
Aids liver function
Most Useful Review
In traditional medicine, silymarin is known for treating liver and gallbladder conditions, promoting lactation, and preventing cancer. It helps the liver detoxify from poisons, such as snakebites. My uncle, who was a heavy drinker, took it for three months, resulting in a notable improvement in his skin tone and overall health.
Dha
7
DHA's potential in cancer therapy
DTX2 attenuates Lenvatinib-induced ferroptosis by suppressing docosahexaenoic acid biosynthesis through HSD17B4-dependent peroxisomal β-oxidation in hepatocellular carcinoma.
Most Relevant Research
In our exploration of liver cancer treatment, we found that combinations of Lenvatinib—an established first-line therapy—and docosahexaenoic acid (DHA) can uniquely influence outcomes. The focus was on understanding how Lenvatinib resistance develops in hepatocellular carcinoma (HCC) and the potential role of DHA in this context.
Through comprehensive studies, including CRISPR screening in liver cancer cells, we discovered that a protein called DTX2 strongly contributes to Lenvatinib resistance. This protein helps protect the cancer cells from a type of cell death known as ferroptosis, which Lenvatinib usually triggers. Interestingly, we learned that DTX2 does this by reducing DHA levels, a fatty acid that plays a crucial role in cellular health.
In our findings, when we added DHA to Lenvatinib treatment, it appeared to counteract DTX2's protective effect against ferroptosis. The study emphasized that using DHA in combination with Lenvatinib could potentially offer a new therapeutic pathway for patients facing drug resistance in liver cancer.
Overall, the relationship between DTX2, DHA production, and Lenvatinib resistance presents an exciting avenue for further exploration in cancer treatment strategies.
Through comprehensive studies, including CRISPR screening in liver cancer cells, we discovered that a protein called DTX2 strongly contributes to Lenvatinib resistance. This protein helps protect the cancer cells from a type of cell death known as ferroptosis, which Lenvatinib usually triggers. Interestingly, we learned that DTX2 does this by reducing DHA levels, a fatty acid that plays a crucial role in cellular health.
In our findings, when we added DHA to Lenvatinib treatment, it appeared to counteract DTX2's protective effect against ferroptosis. The study emphasized that using DHA in combination with Lenvatinib could potentially offer a new therapeutic pathway for patients facing drug resistance in liver cancer.
Overall, the relationship between DTX2, DHA production, and Lenvatinib resistance presents an exciting avenue for further exploration in cancer treatment strategies.
8
Support for cancer
Most Useful Review
I took this to my mother, a cancer patient. I've read much praise for it concerning those on the keto diet. The packaging is large, and the fish monk is easy for her to swallow, suiting her dietary needs. The ingredients are excellent for a cancer patient, and my mother began today. The quality of this product is also highly esteemed. My mother is 72; I pray for her healing.
L Glutathione
7
Nano-silymarin shows potential benefits
Evaluation of Oral Nano-Silymarin Formulation Efficacy in the Prevention of Hand-Foot Syndrome and Neuropathy Induced by XELOX or m-FOLFOX6 Regimens in Metastatic Colorectal Cancer: A Triple-Blinded, Randomized Clinical Trial.
Most Relevant Research
We conducted a triple-blinded, randomized clinical trial involving 60 patients to explore if nano-silymarin could reduce neuropathy and hand-foot syndrome caused by popular chemotherapy regimens used for metastatic colorectal cancer.
Patients received nano-silymarin during their treatment, and we assessed the severity of any side effects after three and six chemotherapy cycles.
While the study suggests that nano-silymarin might help prevent these adverse reactions, more extensive research is needed to confirm these findings and examine different doses.
Patients received nano-silymarin during their treatment, and we assessed the severity of any side effects after three and six chemotherapy cycles.
While the study suggests that nano-silymarin might help prevent these adverse reactions, more extensive research is needed to confirm these findings and examine different doses.
8.8
Body detoxification
Most Useful Review
Glutathione is a naturally occurring substance in our bodies, composed of amino acids. It detoxifies the liver of harmful chemicals, pollutants, toxins, and drugs. If overburdened with toxins, glutathione processing becomes insufficient, leading to increased disease susceptibility, including cancer and Parkinson's. Thus, nourishing the body from the outside is vital; this supplement performs excellently.
Elderberry Sambucus
9
Vitamin C enhances immune response
Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response.
Most Relevant Research
We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
9.5
Prostate cancer prevention
Most Useful Review
This product is very useful in preventing prostate cancer and provides general benefits to the body.
Pancreatin
7
Peptides show promise in cancer
Soybean β-Conglycinin and Cowpea β-Vignin Peptides Inhibit Breast and Prostate Cancer Cell Growth: An In Silico and In Vitro Approach.
Most Relevant Research
We explored the potential of peptides derived from soybean and cowpea proteins to inhibit breast and prostate cancer cell growth. After hydrolyzing these proteins with pancreatin, the resulting peptides showed promise in laboratory tests. Notably, one peptide, VIPAAY, demonstrated a strong ability to interact with the Bcl-2 protein, similar to a popular cancer drug called Venetoclax. However, while initial findings are encouraging, further research is necessary to confirm these results and understand their true impact on cancer treatment.
9.5
Immune system support
Most Useful Review
I took Mega-Zim instead of the German Wobenzym, and it has proven to be even better in terms of enzyme composition. I took 5 tablets four times a day for ten days. It played a crucial role in exposing cancer cells to my immune system, allowing it to fight effectively. I consumed Mega-Zim an hour before meals with warm water, specifically to enrich my blood with enzymes. The quality and results were excellent, and I highly recommend it.
Cat Claw
4
Inconclusive evidence on cat's claw
Systemic therapies for preventing or treating aromatase inhibitor-induced musculoskeletal symptoms in early breast cancer.
Most Relevant Research
We examined the role of cat's claw in managing aromatase inhibitor-induced musculoskeletal symptoms (AIMSS) among women with early-stage breast cancer. This study assessed various systemic therapies, including cat's claw, to determine their effectiveness in alleviating these painful symptoms.
The evidence surrounding cat's claw showed some potential benefits, as it was part of trials that reported clinically meaningful reductions in pain scores. However, the overall findings about the effectiveness of cat's claw specifically were inconclusive due to the complexity and variability of the treatment methods used across the studies.
Importantly, we observed that, while cat's claw was included in some therapeutic explorations, the data failed to provide robust conclusions about its effectiveness or safety for breast cancer symptoms. The review highlighted the need for more rigorous research to truly understand how cat's claw may impact cancer-related pain management and whether it can recommend this treatment confidently.
The evidence surrounding cat's claw showed some potential benefits, as it was part of trials that reported clinically meaningful reductions in pain scores. However, the overall findings about the effectiveness of cat's claw specifically were inconclusive due to the complexity and variability of the treatment methods used across the studies.
Importantly, we observed that, while cat's claw was included in some therapeutic explorations, the data failed to provide robust conclusions about its effectiveness or safety for breast cancer symptoms. The review highlighted the need for more rigorous research to truly understand how cat's claw may impact cancer-related pain management and whether it can recommend this treatment confidently.
9.5
Supports healing process
Most Useful Review
Cat's Claw is an effective detoxifier and is recommended for individuals recovering from chemotherapy and radiation therapy. It aids the immune system and exhibits antitumour activity against cancer. The plant also facilitates wound healing. I find it beneficial for both my son and me in our recovery.
Astragalus
7
Positive effects of herbal treatment
The effect of a traditional Chinese prescription for a case of lung carcinoma.
Most Relevant Research
We examined the effectiveness of Ninjin Yoei To (NYT), a traditional herbal medicine that contains astragalus root among other ingredients, in treating lung cancer. Over a period of 7 weeks, an elderly patient received a daily dose of 15 grams of NYT.
During the study, we observed notable changes in the patient's health. The levels of tumor markers, specifically CEA and CA19-9, decreased. Additionally, the patient’s symptoms improved significantly as her cough vanished and her appetite returned, indicating an enhancement in her overall well-being.
While the study did not isolate the effects of astragalus root alone, the positive outcomes suggest that traditional herbal combinations, including this ingredient, may offer benefits for cancer patients. The assessments based on yin-yang and xu-shi diagnostic systems even indicated a shift in the patient’s health status.
Although NYT is a multi-component herbal formula, we still see it enhancing quality of life for patients facing malignancies. Hence, incorporating such traditional remedies might be a valuable aspect of holistic care in cancer treatment.
During the study, we observed notable changes in the patient's health. The levels of tumor markers, specifically CEA and CA19-9, decreased. Additionally, the patient’s symptoms improved significantly as her cough vanished and her appetite returned, indicating an enhancement in her overall well-being.
While the study did not isolate the effects of astragalus root alone, the positive outcomes suggest that traditional herbal combinations, including this ingredient, may offer benefits for cancer patients. The assessments based on yin-yang and xu-shi diagnostic systems even indicated a shift in the patient’s health status.
Although NYT is a multi-component herbal formula, we still see it enhancing quality of life for patients facing malignancies. Hence, incorporating such traditional remedies might be a valuable aspect of holistic care in cancer treatment.
9.5
Extra energy gained
Most Useful Review
This Astragalus extract provides me with extra energy while undergoing cancer treatments.
Grape Seed Extract
9
Vitamin C enhances immune response
Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response.
Most Relevant Research
We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
9.5
Vitality boost
Most Useful Review
I drink it consistently. At the end of my cancer journey, I consulted a second opinion hospital and continue to take cancer research with a prescription from a long-time American university professor. I believe this has been beneficial as I strive to remain energetic despite being given a life expectancy of only three months.
Beta Carotene
4
RAR-β deletion alters pancreatic cancer
Retinoic acid receptor-β deletion in a model of early pancreatic ductal adenocarcinoma (PDAC) tumorigenesis.
Most Relevant Research
We examined how the deletion of the retinoic acid receptor beta (RAR-β) impacts cancer development in the pancreas. Using a specific mouse model designed for this study, we selectively knocked out the RAR-β gene to see how this would affect pancreatic cells and their behavior in relation to cancer.
Our findings revealed that a lack of RAR-β led to decreased cell proliferation in the pancreatic acinar cells. In simpler terms, without this receptor, the cells were less likely to multiply, which is significant because uncontrolled cell growth is a hallmark of cancer. Interestingly, even in the absence of an activation mutation in the KRas gene, levels of SOX9—a protein vital for pancreatic cancer formation and maintenance—increased in the knockout models.
This suggests that while RAR-β deletion seems to inhibit cell growth, it paradoxically raises SOX9 levels, which could play a complex role in cancer progression. Ultimately, we uncovered that retinoic acid signaling, particularly through RAR-β, may have a nuanced influence on pancreatic cancer development, but we did not directly assess the effects of vitamin A treatments themselves nor did we find universally beneficial effects in this model.
Our findings revealed that a lack of RAR-β led to decreased cell proliferation in the pancreatic acinar cells. In simpler terms, without this receptor, the cells were less likely to multiply, which is significant because uncontrolled cell growth is a hallmark of cancer. Interestingly, even in the absence of an activation mutation in the KRas gene, levels of SOX9—a protein vital for pancreatic cancer formation and maintenance—increased in the knockout models.
This suggests that while RAR-β deletion seems to inhibit cell growth, it paradoxically raises SOX9 levels, which could play a complex role in cancer progression. Ultimately, we uncovered that retinoic acid signaling, particularly through RAR-β, may have a nuanced influence on pancreatic cancer development, but we did not directly assess the effects of vitamin A treatments themselves nor did we find universally beneficial effects in this model.
8.8
Enhances immunity
Most Useful Review
A healthy mind is found in a healthy body! When ingested, beta-carotene transforms into retinol, a vital precursor to vitamin A. It requires fats for absorption. This provitamin helps deliver retinol while shielding cells from cancer radicals and preventing heart diseases. It even lowers cholesterol levels. I take it twice annually paired with vitamin D3 during meals that include fat. I hope this review is beneficial!
Calcium Citrate
8
Vitamin D analogs in prostate cancer
[New insights of vitamin D-based therapy for prostate cancer].
Most Relevant Research
We explored the potential benefits of a vitamin D analog in treating prostate cancer, which is a major cause of cancer-related deaths among men. Our work focused on understanding how this vitamin D form impacts cancer resistance and the tumor microenvironment. We used the Pten mouse model to observe the therapeutic effects of the vitamin D analog.
One significant finding was that combining this vitamin D analog with the chemotherapy drug docetaxel could overcome resistance seen in some prostate cancer cases. This combination showed promising results in primary cancer spheroids and xenografts from a patient whose cancer had resisted both docetaxel and androgen deprivation therapy.
These insights suggest that vitamin D analogs might offer new and effective strategies for managing advanced prostate cancer, particularly for those patients who have not responded well to standard treatments.
One significant finding was that combining this vitamin D analog with the chemotherapy drug docetaxel could overcome resistance seen in some prostate cancer cases. This combination showed promising results in primary cancer spheroids and xenografts from a patient whose cancer had resisted both docetaxel and androgen deprivation therapy.
These insights suggest that vitamin D analogs might offer new and effective strategies for managing advanced prostate cancer, particularly for those patients who have not responded well to standard treatments.
9.5
Breast cancer concern
Most Useful Review
Wonderful product! Highly recommend it! The tablets are not as large as others claim. I typically take one or two tablets several times a day, but it's best to take two at night for better sleep. They are significantly smaller than the calcium pills I previously took, which is a huge plus! I will certainly purchase them again! It's also important to mention they are soy-free, which is crucial for me as I have had breast cancer.
MSM
5
Moderate efficacy, high recurrence
Electrocautery ablation therapy for anal intraepithelial carcinoma with high-resolution anoscopy.
Most Relevant Research
We investigated the effectiveness and safety of electrocautery ablation for treating high-grade squamous intraepithelial lesions (HSILs) in men who have sex with men (MSM), including those living with HIV. Our study included 20 participants who underwent this treatment and were followed closely with high-resolution anoscopy (HRA) to monitor outcomes.
The primary goal was to see how well this approach worked at curing local HSILs after six months. While electrocautery ablation was noted to be moderately effective, we also discovered that the recurrence rates were quite high. This suggests that even with comprehensive biopsies from the anal canal, we could not fully prevent the return of these lesions.
Overall, our findings highlight that while this treatment can be helpful for MSM, the risk of recurrence is significant. More research involving larger participant groups and longer follow-ups is necessary to improve treatment outcomes. We believe it is crucial to continue refining strategies for managing HSIL to enhance the health of this community.
The primary goal was to see how well this approach worked at curing local HSILs after six months. While electrocautery ablation was noted to be moderately effective, we also discovered that the recurrence rates were quite high. This suggests that even with comprehensive biopsies from the anal canal, we could not fully prevent the return of these lesions.
Overall, our findings highlight that while this treatment can be helpful for MSM, the risk of recurrence is significant. More research involving larger participant groups and longer follow-ups is necessary to improve treatment outcomes. We believe it is crucial to continue refining strategies for managing HSIL to enhance the health of this community.
9.5
Improves recovery and health
Most Useful Review
Methylsulfonylmethane (MSM) is excellent for my ballet training as it supports my joints and aids recovery. The effects are tangible; it's best taken with silicon supplements. MSM not only helps with joint pain and cholesterol levels but also possesses anti-cancer properties, boosts immunity, detoxifies the liver, promotes normal blood levels, and enhances brain function.
Glucosamine Chondroitin Formulas
5
Moderate efficacy, high recurrence
Electrocautery ablation therapy for anal intraepithelial carcinoma with high-resolution anoscopy.
Most Relevant Research
We investigated the effectiveness and safety of electrocautery ablation for treating high-grade squamous intraepithelial lesions (HSILs) in men who have sex with men (MSM), including those living with HIV. Our study included 20 participants who underwent this treatment and were followed closely with high-resolution anoscopy (HRA) to monitor outcomes.
The primary goal was to see how well this approach worked at curing local HSILs after six months. While electrocautery ablation was noted to be moderately effective, we also discovered that the recurrence rates were quite high. This suggests that even with comprehensive biopsies from the anal canal, we could not fully prevent the return of these lesions.
Overall, our findings highlight that while this treatment can be helpful for MSM, the risk of recurrence is significant. More research involving larger participant groups and longer follow-ups is necessary to improve treatment outcomes. We believe it is crucial to continue refining strategies for managing HSIL to enhance the health of this community.
The primary goal was to see how well this approach worked at curing local HSILs after six months. While electrocautery ablation was noted to be moderately effective, we also discovered that the recurrence rates were quite high. This suggests that even with comprehensive biopsies from the anal canal, we could not fully prevent the return of these lesions.
Overall, our findings highlight that while this treatment can be helpful for MSM, the risk of recurrence is significant. More research involving larger participant groups and longer follow-ups is necessary to improve treatment outcomes. We believe it is crucial to continue refining strategies for managing HSIL to enhance the health of this community.
9.5
Reduces cancer risk
Most Useful Review
Glucosamine sulfate is a simple sugar that prevents glucose oxidation. The dosage is critical; for an 80 kg person, 2000 mg daily can lead to heart issues and reduced lifespan if taken young. However, studies reveal that for those over 50, glucosamine is linked to a 41% lower risk of mortality from respiratory infections and a significant reduction in lung and colorectal cancer risks. Though I don’t take it as I’m still young, it provides my grandmother with crucial relief for her knees and potentially extends her life.