Probiotic supplement alleviates GERD symptomsEfficacy of a Food Supplement Containing LA14, Peptides, and a Multivitamin Complex in Improving Gastroesophageal Reflux Disease-Related Outcomes and Quality of Life of Subjects Showing Mild-to-Moderate Gastroesophageal Reflux Disease.
High relevance to GERD treatment
We investigated the impact of a dietary supplement containing lactobacillus acidophilus, bioactive peptides, and vitamins on individuals with mild-to-moderate gastroesophageal reflux disease (GERD). Conducted as a randomized, double-blind, placebo-controlled study, we followed fifty-six adults over 28 days.
Participants reported a significant reduction in heartburn frequency and severity with the active supplement compared to the placebo. They also noted a decreased reliance on over-the-counter medications and improved quality of life. Overall, this supplement appears to bring meaningful relief to those struggling with GERD symptoms.
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We aimed to explore the effectiveness of a specific probiotic mixture called Ecologic®Relief in treating constipation among pregnant women. Over four weeks, participants reported significant improvements in their bowel habits, including increased defecation frequency and reduced sensations of obstruction and incomplete evacuation.
Importantly, we noted that the probiotic mixture also seemed to decrease reflux episodes from 60% to 20%. This suggests that not only does Ecologic®Relief help with constipation, but it may also provide relief from reflux symptoms during pregnancy. We believe more extensive studies will be beneficial to confirm these findings.
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Probiotics repair DNA in GERD sp. Facilitate the Repair of DNA Damage Caused by Bile-Induced Reactive Oxygen Species in Experimental Models of Gastroesophageal Reflux Disease.
Research indicates significant probiotic impact
We explored the effects of Lactobacillus species on bile-induced DNA damage in esophageal cells, which occurs during gastroesophageal reflux disease (GERD). By exposing these bacteria to a bile-rich environment, we found they could survive and interact beneficially with injured cells.
Notably, adding Lactobacillus after bile injury boosted the repair of DNA damage and lessened inflammation. This suggests that these probiotics could play a role in protecting against long-term complications of GERD, like Barrett's esophagus and esophageal cancer.
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Bifidobacterium lactis aids reflux recoveryTherapeutic Evaluation of subsp. MH-02 as an Adjunctive Treatment in Patients with Reflux Esophagitis: A Randomized, Double-Blind, Placebo-Controlled Trial.
High relevance therapeutic impact
We examined the effects of Bifidobacterium lactis as a complementary treatment for reflux esophagitis (RE) in a randomized, double-blind, placebo-controlled study. A total of 110 RE patients received rabeprazole while being supplemented with either Bifidobacterium or a placebo over 8 weeks.
Our findings showed that the probiotic group experienced quicker symptom relief and a longer time before symptoms returned, compared to the placebo. We also noted improvements in gut microbiota diversity following the treatment. Thus, Bifidobacterium lactis appears to provide significant benefits as an adjunct therapy for managing reflux symptoms.
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B. lactis improves GI functionDose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults.
Study demonstrates probiotic effectiveness
In our exploration, we examined how Bifidobacterium lactis HN019 could influence gut transit time and gastrointestinal symptoms. We enrolled 100 adults with functional GI issues, splitting them into groups to receive either high-dose, low-dose, or placebo for two weeks.
We found that both treatment groups experienced significant reductions in gut transit times and a decrease in various GI symptoms. The placebo group did not show any notable improvements.
Overall, B. lactis HN019 seems effective in easing reflux-related symptoms and improving gut health.
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