Our research explored the effects of a new calcium-loaded complex, made from Antarctic krill protein and enriched with pectin, on calcium absorption and bone health in mice with calcium deficiency. We created a model that simulated calcium deficiency, which is a significant concern as it can contribute to osteoporosis.
We observed that chronic calcium deprivation led to decreased calcium absorption and deterioration of bone structure. However, the P + Ca + HMP complex significantly improved calcium retention and increased the strength of the femur, indicating a positive impact on bone health.
Additionally, this complex improved the structure of the trabecular network, which is essential for maintaining strong bones. The presence of beneficial bacteria in the gut also rose after the intervention, and these were linked to better calcium absorption and bone synthesis. Overall, these findings point to the potential of the P + Ca + HMP complex as an effective calcium supplement that could help prevent calcium deficiency and thus support bone health.
Read More
8
Calcium's role in osteoporosis explored
Is there a disparity in osteoporosis referral and treatment among people with affective disorders? A ten-year data linkage study.
We sought to understand whether individuals with affective disorders (AD) receive different levels of osteoporosis treatment compared to those without these mental health conditions. To do this, we analyzed a large group of people over a ten-year period, looking at how often patients with AD received calcium prescriptions and referrals for osteoporosis screening.
Our findings show that people with AD were more likely to receive calcium treatments, including calcium alone and calcium combined with vitamin D, compared to healthy controls. Specifically, the study highlighted that individuals with AD had a 64% higher chance of receiving a calcium prescription and a 125% higher likelihood of being referred for screening within two years of their diagnosis.
Despite these increased rates of screening and treatment, there remains a question about whether such efforts are effectively reducing the risk of osteoporosis and fractures in this vulnerable group. Factors such as age, sex, ethnic background, and use of analgesics also played significant roles in the treatment pathways for these patients, indicating that while there are advancements in management, the overall effectiveness still requires further investigation.
Read More
9
Combination therapy for osteoporosis
Effect of salmon calcitonin combined with calcium antagonist on blood calcium and phosphorus ion concentration in osteoporosis rats.
We explored how salmon calcitonin (sCT) works in tandem with calcium antagonists—specifically verapamil, nifedipine, and diltiazem—to influence blood calcium and phosphorus levels in female rats with osteoporosis post-ovarian removal.
The study involved a systematic approach where we administered these combinations to different groups of osteoporotic rats and measured their blood levels. Our findings revealed that combining sCT with nifedipine had a particularly strong effect in lowering both calcium and phosphorus in the blood, outperforming the use of sCT alone.
Our analysis indicated that while sCT with nifedipine was most effective, the combinations with verapamil and diltiazem also showed beneficial effects, albeit to a lesser extent. These insights provide valuable information on how combination therapies might be targeted for treating postmenopausal osteoporosis, potentially paving the way for more effective treatment options in human patients.
Read More
Most Useful Reviews
9
Stronger nails
11 people found this helpful
The result is impressive! My husband has osteoporosis in parts of his spine, and my nails were as thin as paper. After two months, my nails became much stronger, and my partner's back pain has improved. We intend to undergo examination for clinical confirmation of the results.
Read More
9
Numbers improved
9 people found this helpful
This is a great product, but I have some qualms. I like it and have taken it for a while now. It has helped my osteoporosis; my recent bone density test showed that my condition has improved, and I am now at the osteopenia level. However, I had an issue with the product's packaging – the bottle was shattered upon arrival. I managed to transfer the tablets to another usable bottle.
Read More
9
Standard bone density
8 people found this helpful
The effect is favourable and the absorption is good. My mother has been taking hormones and the doctor advised her to consume calcium to combat osteoporosis. She has been taking this supplement and her bone mineral density and calcium levels are now in standard range. We will continue purchasing it.
Our research explored the effects of a new calcium-loaded complex, made from Antarctic krill protein and enriched with pectin, on calcium absorption and bone health in mice with calcium deficiency. We created a model that simulated calcium deficiency, which is a significant concern as it can contribute to osteoporosis.
We observed that chronic calcium deprivation led to decreased calcium absorption and deterioration of bone structure. However, the P + Ca + HMP complex significantly improved calcium retention and increased the strength of the femur, indicating a positive impact on bone health.
Additionally, this complex improved the structure of the trabecular network, which is essential for maintaining strong bones. The presence of beneficial bacteria in the gut also rose after the intervention, and these were linked to better calcium absorption and bone synthesis. Overall, these findings point to the potential of the P + Ca + HMP complex as an effective calcium supplement that could help prevent calcium deficiency and thus support bone health.
Read More
9
Combination therapy for osteoporosis
Effect of salmon calcitonin combined with calcium antagonist on blood calcium and phosphorus ion concentration in osteoporosis rats.
We explored how salmon calcitonin (sCT) works in tandem with calcium antagonists—specifically verapamil, nifedipine, and diltiazem—to influence blood calcium and phosphorus levels in female rats with osteoporosis post-ovarian removal.
The study involved a systematic approach where we administered these combinations to different groups of osteoporotic rats and measured their blood levels. Our findings revealed that combining sCT with nifedipine had a particularly strong effect in lowering both calcium and phosphorus in the blood, outperforming the use of sCT alone.
Our analysis indicated that while sCT with nifedipine was most effective, the combinations with verapamil and diltiazem also showed beneficial effects, albeit to a lesser extent. These insights provide valuable information on how combination therapies might be targeted for treating postmenopausal osteoporosis, potentially paving the way for more effective treatment options in human patients.
Read More
8
Calcium's role in osteoporosis explored
Is there a disparity in osteoporosis referral and treatment among people with affective disorders? A ten-year data linkage study.
We sought to understand whether individuals with affective disorders (AD) receive different levels of osteoporosis treatment compared to those without these mental health conditions. To do this, we analyzed a large group of people over a ten-year period, looking at how often patients with AD received calcium prescriptions and referrals for osteoporosis screening.
Our findings show that people with AD were more likely to receive calcium treatments, including calcium alone and calcium combined with vitamin D, compared to healthy controls. Specifically, the study highlighted that individuals with AD had a 64% higher chance of receiving a calcium prescription and a 125% higher likelihood of being referred for screening within two years of their diagnosis.
Despite these increased rates of screening and treatment, there remains a question about whether such efforts are effectively reducing the risk of osteoporosis and fractures in this vulnerable group. Factors such as age, sex, ethnic background, and use of analgesics also played significant roles in the treatment pathways for these patients, indicating that while there are advancements in management, the overall effectiveness still requires further investigation.
Read More
7
Calcium's complex effect on mineralization
miR-125b differentially impacts mineralization in dexamethasone and calcium-treated human mesenchymal stem cells.
We explored how calcium treatment influences bone mineralization, particularly in the context of osteoporosis. Our study involved human mesenchymal stem cells (hMSCs) that were cultured in two different environments: one with calcium and another with dexamethasone, a medication often used to treat inflammation and other conditions.
Interestingly, while both treatments increased mineralization of hMSCs, we noted that levels of a specific microRNA, miR-125b, decreased with exposure to either calcium or dexamethasone. When we introduced a miR-125b mimic in the dexamethasone-treated cells, mineralization increased; however, it did the opposite in the calcium-treated cells. This suggests that calcium's effect can vary significantly depending on the context in which it is applied.
We also identified key targets of miR-125b that play roles in bone development, highlighting the complexity behind how calcium treatments might work in conjunction with other factors like dexamethasone. Overall, our findings contribute to a deeper understanding of bone metabolism and suggest that while calcium is important, its effectiveness might not be straightforward and may require further exploration.
Read More
5
Calcium's risks for kidney stones
Association between calcium and vitamin D supplementation and increased risk of kidney stone formation in patients with osteoporosis in Southwest China: a cross-sectional study.
We explored the effects of calcium and vitamin D supplementation on osteoporosis, particularly focusing on the risk of kidney stones. In our study, 204 older adults in southwest China took daily doses of calcium and vitamin D for at least a year. We used various statistical analyses to understand the relationship between these supplements and kidney stone formation.
Our findings reveal that there is a potential link between the use of calcium supplements for osteoporosis and an increased risk of developing kidney stones. It seems that a history of kidney stones can elevate the likelihood of experiencing them again while undergoing such supplementation, likely due to higher urinary calcium levels.
While calcium is essential for bone health, our results suggest that patients need to be cautious. This research highlights the importance of monitoring kidney health while receiving calcium and vitamin D treatment to prevent complications like kidney stones.
The result is impressive! My husband has osteoporosis in parts of his spine, and my nails were as thin as paper. After two months, my nails became much stronger, and my partner's back pain has improved. We intend to undergo examination for clinical confirmation of the results.
Read More
9
Numbers improved
9 people found this helpful
This is a great product, but I have some qualms. I like it and have taken it for a while now. It has helped my osteoporosis; my recent bone density test showed that my condition has improved, and I am now at the osteopenia level. However, I had an issue with the product's packaging – the bottle was shattered upon arrival. I managed to transfer the tablets to another usable bottle.
Read More
9
Standard bone density
8 people found this helpful
The effect is favourable and the absorption is good. My mother has been taking hormones and the doctor advised her to consume calcium to combat osteoporosis. She has been taking this supplement and her bone mineral density and calcium levels are now in standard range. We will continue purchasing it.
Read More
9
Bone health support
1 people found this helpful
Best! I trust mykind products. This was my first purchase, and I received a discount. It's fantastic to find a top-quality combination of D3 and K2 for bone health and osteoporosis!
Read More
9
Absorption aid
My Kind calcium is excellent for individuals like me who struggle with calcium absorption! I've been taking it for years to manage my osteoporosis.
Osteoporosis is a medical condition characterized by weakened bones, making them fragile and more prone to fractures. This condition occurs when the body loses too much bone mass, doesn't make enough bone, or a combination of both. As bones lose density, they can break more easily, often as a result of minor falls or injury. Osteoporosis is often referred to as a "silent disease" because bone loss occurs without any symptoms until a fracture occurs, often in the hip, spine, or wrist.
Risk factors for developing osteoporosis include age, gender (it’s more common in women), family history, low body weight, and certain medical conditions and medications. Lifestyle choices such as smoking, excessive alcohol consumption, and a diet low in calcium and vitamin D can also contribute to bone loss. Regular weight-bearing exercise, ensuring adequate nutrition, and, in some cases, medications can help prevent or manage osteoporosis. If you believe you may be at risk, it is important to consult with a healthcare professional for appropriate screening and intervention options.
Calcium is a chemical element represented by the symbol Ca and atomic number 20. It is an essential mineral in the body, playing a critical role in various physiological processes. As one of the most abundant elements in nature, calcium is particularly vital for maintaining strong bones and teeth, where about 99% of the body's calcium is stored. Beyond its structural function, calcium is crucial in muscle contraction, blood clotting, and nerve transmission, making it a key player in overall health.
Dietary sources of calcium include dairy products such as milk, yogurt, and cheese, as well as leafy green vegetables, nuts, seeds, and fortified foods. The recommended daily intake of calcium varies by age and sex, but generally, adults should aim for approximately 1,000 mg per day. For those who may struggle to meet their needs through diet alone, calcium supplements are available but should be taken with caution. It's essential to consult with a healthcare provider before starting any supplement regimen to avoid potential side effects or interactions with medications.
Calcium plays a crucial role in maintaining bone health and is often recommended as a key nutrient for individuals at risk of osteoporosis, a condition characterized by weak and brittle bones. Adequate calcium intake helps to support bone density, making bones stronger and less susceptible to fractures. For adults, the recommended daily intake of calcium is around 1,000 to 1,200 mg, depending on age and gender. Including calcium-rich foods like dairy products, leafy greens, and fortified foods can significantly contribute to achieving this daily requirement.
However, it's important to note that calcium alone may not be sufficient to prevent or treat osteoporosis. A holistic approach that includes vitamin D for calcium absorption, regular weight-bearing exercise, and lifestyle modifications is essential for maintaining bone health. Additionally, individuals should consult with healthcare professionals to assess their specific needs and explore comprehensive osteoporosis management strategies. In sum, while calcium is vital for bone health, it should be part of a broader plan to combat osteoporosis effectively.
When it comes to taking supplements for osteoporosis, many users suggest that noticeable results can take some time, often in the range of a few weeks to a few months. For instance, one review indicates that improvements in bone health indicators were confirmed after taking the supplement for over three months (Read Review). Another user's experience mentions significant improvement in nail strength and overall bone health after several months of use (Read Review). However, some users have experienced positive changes, such as stronger nails, after just two months (Read Review).
In general, it seems that most users report improvements in their condition or indicators of bone health within a period of two to three months, with consistent use being key to achieving and maintaining these results. If you're considering starting this supplement for osteoporosis, it may be helpful to monitor your progress regularly and discuss any changes with a healthcare professional to ensure those results align with your personal health needs.
The role of calcium in managing osteoporosis shows some promise, but the overall evidence remains mixed. Studies indicate that while calcium is often used in conjunction with other osteoporosis treatments, such as zoledronate or alendronate, its isolated impact on bone density and health is less clear. For instance, a thorough review suggested that calcium plays a role when combined with these therapies, but its individual effectiveness lacks robust validation ([1]). Additionally, while an innovative calcium complex derived from Antarctic krill protein did show positive effects on bone health in a animal model, this research has not yet translated into clear human applications for osteoporosis prevention ([2]).
Concurrent research has demonstrated both benefits and potential risks associated with calcium supplementation, such as an increased risk of kidney stones in older adults ([5]). This duality underscores the necessity for further studies to clarify the role of calcium in osteoporosis treatment and to determine the best methods for supplementation. Overall, while calcium is a fundamental component of bone health, its use as a standalone treatment for osteoporosis could benefit from more targeted research to assess its efficacy and safety in diverse populations.
Users have reported varying degrees of improvement in their osteoporosis symptoms and overall bone health after using this calcium supplement. For instance, one reviewer noted that their husband experienced a significant reduction in back pain after just two months of use, while they also observed their own nails becoming much stronger during this time (Read Review) . Another user shared that after several months on the supplement, they received clinical confirmation of improved bone health indicators, emphasizing the effectiveness of vitamins D3 and K2 in aiding calcium absorption (Read Review).
Additionally, numerous users highlighted the supplement's role in enhancing bone mineral density and calcium levels. One user reported that their mother's bone mineral density and calcium levels returned to a standard range after consistently using the product (Read Review) . Moreover, several reviewers specifically noted improvements in their ability to manage osteoporosis without side effects, appreciating the product’s gentle formulation compared to other supplements they had tried (Read Review). While these experiences are encouraging, it's worth remembering that individual results can vary, so progress may differ from person to person.
Based on user reviews, many individuals combining this calcium supplement with other nutrients like vitamins D3 and K2 have experienced enhanced benefits for managing osteoporosis. For instance, one user noted that their mother, who was already taking hormones for osteoporosis, incorporated this supplement into her regimen and achieved a return of her bone mineral density and calcium levels to standard ranges, demonstrating the effectiveness of supplementation in conjunction with medical advice (Read Review). Additionally, reviewers have pointed out that this supplement's formulation includes vital ingredients that facilitate calcium absorption, which is crucial for bone health and osteoporosis management (Read Review).
Furthermore, users have highlighted the importance of taking this supplement alongside other minerals, specifically suggesting the inclusion of magnesium for optimal results (Read Review). This tailored approach to combining calcium with additional supportive nutrients seems to enhance efficacy in addressing osteoporosis, making it a popular choice for those seeking to improve their bone health. Many have reported positive experiences with this combination, citing improvements in bone health indicators as a compelling reason to maintain consistent use (Read Review).
Based on user reviews, there seems to be a consensus on the importance of adequate calcium intake combined with other nutrients like vitamins D3 and K2 for effectively managing osteoporosis. Users reported positive outcomes from supplements that provided around 800mg of calcium per serving, along with supportive vitamins, which enhanced absorption and overall effectiveness in improving bone health. For instance, one user noted significant improvements in bone health indicators after using a calcium supplement that included these essential nutrients for three months Read Review.
Additionally, reviewers emphasized the comfort of their digestive systems when taking these supplements. Several mentioned that they could take the recommended dosages without adverse side effects, making it easier to maintain compliance with their treatment regimen. Others highlighted the importance of taking calcium alongside other vitamins for maximized benefits in bone health Read Review. Thus, while specific dosages may vary based on individual needs, a blend of calcium and vitamins appears to be key in the reported success stories.
9
Effective results
I've taken this supplement for over three months due to osteoporosis. After repeated densitometry, my bone health indicators improved, confirming its effectiveness. The vitamins D3 and K2 aid in calcium absorption, making this product a great choice for skeletal support.
7.5
Bone health improvement
Garden of Life's MyKind Organics Organic Plant Calcium is a brilliant plant-based supplement providing 800mg of calcium per serving from organic algae, plus magnesium, vitamin D3, and vitamin K2. This formula supports bone health and reduces the risk of osteoporosis. After several months of use, I’ve noticed a significant improvement in my nail strength and overall bone health. I appreciate its organic ingredients and highly recommend it for anyone looking for a natural way to maintain calcium levels and support bone health.
9
Stronger nails
11 people found this helpful
The result is impressive! My husband has osteoporosis in parts of his spine, and my nails were as thin as paper. After two months, my nails became much stronger, and my partner's back pain has improved. We intend to undergo examination for clinical confirmation of the results.
9
Standard bone density
8 people found this helpful
The effect is favourable and the absorption is good. My mother has been taking hormones and the doctor advised her to consume calcium to combat osteoporosis. She has been taking this supplement and her bone mineral density and calcium levels are now in standard range. We will continue purchasing it.
9
Easier digestion
The quality of this vegetable-based calcium supplement is exceptional. It includes ingredients from fruits and vegetables, making it easier to digest compared to regular calcium. Remember to take it with vitamin D and magnesium for maximum benefit. This product has significantly improved my ability to manage osteoporosis.
4
Calcium's role in osteoporosis unclear
Optimizing bone health in people living with HIV: insights from a network meta-analysis of randomized controlled trials.
We conducted a thorough review of various treatments for osteoporosis in people living with HIV, particularly focusing on the role of calcium. Our analysis included randomized controlled trials that compared different treatment strategies, such as calcium combined with medications like zoledronate or alendronate.
While zoledronate showed promising results in improving bone mineral density, calcium was often used alongside these treatments. Unfortunately, this combination makes it difficult to isolate the specific effects of calcium on osteoporosis. We found that alendronate, although it helped reduce certain bone turnover markers, did not significantly improve bone density.
Overall, the study indicates that while calcium plays a role in treatment combinations, its isolated impact on osteoporosis remains unclear. We emphasized the need for more focused research to determine calcium's true effectiveness in enhancing bone health for those affected by HIV.
9
Calcium complex enhances bone health
A calcium-loaded complex based on Antarctic krill protein and supplemented with pectin promotes calcium absorption and bone health.
Our research explored the effects of a new calcium-loaded complex, made from Antarctic krill protein and enriched with pectin, on calcium absorption and bone health in mice with calcium deficiency. We created a model that simulated calcium deficiency, which is a significant concern as it can contribute to osteoporosis.
We observed that chronic calcium deprivation led to decreased calcium absorption and deterioration of bone structure. However, the P + Ca + HMP complex significantly improved calcium retention and increased the strength of the femur, indicating a positive impact on bone health.
Additionally, this complex improved the structure of the trabecular network, which is essential for maintaining strong bones. The presence of beneficial bacteria in the gut also rose after the intervention, and these were linked to better calcium absorption and bone synthesis. Overall, these findings point to the potential of the P + Ca + HMP complex as an effective calcium supplement that could help prevent calcium deficiency and thus support bone health.
5
Calcium's risks for kidney stones
Association between calcium and vitamin D supplementation and increased risk of kidney stone formation in patients with osteoporosis in Southwest China: a cross-sectional study.
We explored the effects of calcium and vitamin D supplementation on osteoporosis, particularly focusing on the risk of kidney stones. In our study, 204 older adults in southwest China took daily doses of calcium and vitamin D for at least a year. We used various statistical analyses to understand the relationship between these supplements and kidney stone formation.
Our findings reveal that there is a potential link between the use of calcium supplements for osteoporosis and an increased risk of developing kidney stones. It seems that a history of kidney stones can elevate the likelihood of experiencing them again while undergoing such supplementation, likely due to higher urinary calcium levels.
While calcium is essential for bone health, our results suggest that patients need to be cautious. This research highlights the importance of monitoring kidney health while receiving calcium and vitamin D treatment to prevent complications like kidney stones.
References
Wang JC, Chung SM, Wu PT, Tu YK, Lai PC, et al. Optimizing bone health in people living with HIV: insights from a network meta-analysis of randomized controlled trials. EClinicalMedicine. 2025;81:103103. doi:10.1016/j.eclinm.2025.103103
Chen L, Lin S, He X, Ye J, Huang Y, et al. A calcium-loaded complex based on Antarctic krill protein and supplemented with pectin promotes calcium absorption and bone health. Int J Biol Macromol. 2025. doi:10.1016/j.ijbiomac.2025.141634
Ma R, Romano E, Ashworth M, Vancampfort D, Solmi M, et al. Is there a disparity in osteoporosis referral and treatment among people with affective disorders? A ten-year data linkage study. Gen Hosp Psychiatry. 2025;94:56. doi:10.1016/j.genhosppsych.2025.02.009
Chen J, Wang J, Jia W, Zhang Y, Li H, et al. Effect of salmon calcitonin combined with calcium antagonist on blood calcium and phosphorus ion concentration in osteoporosis rats. Eur J Med Res. 2025;30:115. doi:10.1186/s40001-025-02384-y
Shi L, Bao Y, Deng X, Xu X, Hu J. Association between calcium and vitamin D supplementation and increased risk of kidney stone formation in patients with osteoporosis in Southwest China: a cross-sectional study. BMJ Open. 2025;15:e092901. doi:10.1136/bmjopen-2024-092901
Joris V, Balmayor ER, van Griensven M. miR-125b differentially impacts mineralization in dexamethasone and calcium-treated human mesenchymal stem cells. Mol Ther Nucleic Acids. 2025;36:102446. doi:10.1016/j.omtn.2024.102446