'
SCIENTIFIC SCORE
Questionable
Based on 13 Researches
6.8
USERS' SCORE
Questionable
Based on 23 Reviews
5.9
Supplement Facts
Serving Size: 4 Capsules
Serving Per Container:  30
Amount Per Serving
%DV
Vitamin C (from culture of S. cerevisiae)
50 mg
56%
Vitamin D (as D3 from culture of S. cerevisiae)
40 mcg (1,600 IU)
200%
Vitamin K (from culture of S. cerevisiae)
120 mcg
100%
Calcium (naturally occurring from Algae)
1,100 mg
85%
Magnesium (from Algae and Dead Sea minerals)
357 mg
85%
Vitamin K (as K2 MK-7)
50 mcg
+
Strontium (naturally occurring from Algae)
3.8 mg
+
Boron (from Brown Rice Chelate)
3 mg
+
Silica (naturally occurring from Algae)
2.2 mg
+
Vanadium (naturally occurring from Algae)
25 mcg
+
Raw Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, [Lactobacillus bulgaricus, Lactobacillus plantarum] (500 Million CFU).
64 mg
+

Top Medical Research Studies

4
Effectiveness of magnesium on constipation
Effect of reduced daily magnesium oxide doses on laxative effect: a single-center retrospective study.
Study directly addresses magnesium use
We explored how changing the frequency of magnesium oxide (MgO) doses influences its effectiveness in relieving constipation. In this study, we looked at 11 patients who had been regularly using MgO to manage their bowel movements and decided to reduce their daily dose frequency over two weeks.

Initially, patients were taking magnesium three times a day, but we reduced this to either two or one dose per day while keeping the total amount the same. We found that the average number of bowel movements dropped from 7.6 to 6.6 in this period. However, this change wasn't statistically significant, indicating that it may not be clinically meaningful.

Additionally, we measured stool consistency using the Bristol Stool Form Scale and noted no significant difference before and after the dosage adjustment. Our findings suggest that reducing the number of doses does not impact the laxative effect of magnesium oxide. This implies that patients can comfortably manage their magnesium intake without sacrificing effectiveness.
Read More
9
Magnesium effectively aids constipation
The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
Direct assessment of magnesium's effect
We investigated how magnesium supplements affect chronic constipation through a systematic review of randomized controlled trials. The analysis included eight studies with a total of 787 participants. We focused on magnesium oxide among other treatment options and assessed its effectiveness in increasing stool frequency and improving consistency.

The findings were quite promising for magnesium oxide. Our results showed that participants who took magnesium experienced a boost in bowel movements, with an average increase of about 3.7 additional movements per week. This improvement in stool consistency was also noteworthy, scoring higher on the Bristol stool chart.

While other supplements like senna and kiwifruit were explored, they didn't significantly enhance symptoms of constipation in this analysis. Therefore, we suggest that magnesium oxide stands out in this study as a worthwhile option for managing chronic constipation. But it’s essential to remember that further research could help confirm these findings and explore the effects of whole food alternatives.
Read More
7
Calcium reduces constipation risk
Association between dietary calcium intake and constipation in a metabolic syndrome population: evidence from NHANES 2005-2010.
Significant relationship with MetS
We explored how calcium intake relates to constipation, particularly focusing on individuals with metabolic syndrome, a condition that significantly impacts health. Using data from the National Health and Nutrition Examination Survey conducted between 2005 and 2010, we assessed the dietary habits of participants and looked at how often they experienced constipation.

Our findings suggest a noteworthy connection: as dietary calcium intake increases, the risk of constipation decreases among those with metabolic syndrome. This suggests that calcium could play a beneficial role in gastrointestinal health.

By analyzing dietary recalls and bowel movement frequency, we provided valuable insights into how making dietary changes can potentially improve symptoms for those affected by metabolic syndrome. This emphasizes the importance of dietary calcium as a simple yet impactful strategy for managing gastrointestinal issues in this specific population.
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Most Useful Reviews

0
Severe constipation
While I saw many positive reviews, I had a severe reaction with constipation and poor circulation. I’ve had no side effects otherwise, but I’m unable to take it due to the constipation. It's too natural for me.
Read More
9.5
Improved digestion
Good product! Unlike other calcium supplements, this one hasn't caused me constipation, which is essential during pregnancy. My digestive system actually feels improved.
Read More
9.5
No constipation effect
This is quite effective for me. I take four tablets daily and haven’t experienced constipation, making it a very good product.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 13 Researches
6.8
9
Magnesium aids constipation, boosts brain
Defecation after magnesium supplementation enhances cognitive performance in triathletes.
Moderate relevance to magnesium effects
We explored the relationship between magnesium supplementation, defecation, and cognitive performance in elite triathletes. In a carefully designed crossover trial, participants undertook cognitive tests after taking magnesium oxide and after defecation. This study highlighted an interesting potential connection between the state of our digestive system and cognitive abilities.

We found that after magnesium-induced defecation, participants completed cognitive tasks more quickly compared to when they had not defecated. Specifically, the average completion time for the cognitive test dropped significantly after defecation when magnesium was involved. While this suggests that magnesium can aid in relieving constipation, its role in improving overall cognitive function during athletics is also noteworthy.

Although we observed an increase in cognitive performance following magnesium supplementation, it’s important to note that no significant changes in blood flow or oxygen levels were detected in the brain during the test. Instead, we noted decreased oxygen levels in the digestive region, hinting at an increased demand for energy there.

Overall, our findings suggest a potential new avenue for enhancing cognitive function in athletes through magnesium to improve constipation. However, the direct effects of magnesium solely on constipation require further investigation.
Read More
9
Magnesium effectively aids constipation
The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
Direct assessment of magnesium's effect
We investigated how magnesium supplements affect chronic constipation through a systematic review of randomized controlled trials. The analysis included eight studies with a total of 787 participants. We focused on magnesium oxide among other treatment options and assessed its effectiveness in increasing stool frequency and improving consistency.

The findings were quite promising for magnesium oxide. Our results showed that participants who took magnesium experienced a boost in bowel movements, with an average increase of about 3.7 additional movements per week. This improvement in stool consistency was also noteworthy, scoring higher on the Bristol stool chart.

While other supplements like senna and kiwifruit were explored, they didn't significantly enhance symptoms of constipation in this analysis. Therefore, we suggest that magnesium oxide stands out in this study as a worthwhile option for managing chronic constipation. But it’s essential to remember that further research could help confirm these findings and explore the effects of whole food alternatives.
Read More
9
Magnesium aids cancer patient care
Oral application of magnesium-L-threonate enhances analgesia and reduces the dosage of opioids needed in advanced cancer patients-A randomized, double-blind, placebo-controlled trial.
Addresses magnesium's role in constipation
We conducted a randomized, double-blind trial to assess how magnesium-L-threonate, a new compound, might help relieve constipation while enhancing the pain relief effects of opioids in patients with advanced cancer. During the study, patients receiving this treatment were compared with those taking a placebo, allowing us to clearly see the differences in outcomes.

As the trial progressed, we noticed significant improvements in the group taking magnesium-L-threonate. Notably, this treatment not only helped in managing pain more effectively but also significantly alleviated opioid-induced constipation—a common side effect of opioid use. The data indicated that patients on magnesium-L-threonate required lower doses of opioids for pain management while enjoying better gastrointestinal comfort.

Overall, our findings suggest that magnesium-L-threonate is a promising option in the palliative care landscape for cancer patients, addressing both pain relief and constipation, which can greatly enhance their quality of life.
Read More
8
Calcium effects on constipation assessed
Efficacy and Safety of LBSC in Drug Induced Constipation Associated With Functional Gastrointestinal Disorder: A Double-Blind, Randomized, Interventional, Parallel, Controlled Trial a Clinical Study on LBSC for Drug Induced Constipation Associated With FGIDs.
Study complexity limits calcium assessment
We embarked on a study to understand how calcium, alongside other treatments, impacts drug-induced constipation linked to functional gastrointestinal disorders (FGIDs). Our research involved a double-blind, randomized trial with 168 participants suffering from constipation triggered by medications. Participants were divided into two arms: a placebo group and another group receiving a combination of atorvastatin, atenolol, metformin, amitriptyline, and calcium. Both groups took the treatment for 35 days and were monitored for changes in bowel function and constipation severity.

While the study results indicated that the combination treatment, including calcium, was safe and helped manage constipation symptoms associated with FGIDs, it's essential to note that the study design made it challenging to determine the individual effect of calcium. Although participants experienced improvements, we couldn't isolate how much of that success came solely from calcium, given it was part of a multi-drug regimen. Thus, while calcium appeared effective within the combined treatment, the specific role of calcium alone remains unclear.

Importantly, no significant adverse effects were reported, underscoring the safety of this approach. Overall, we found that while the multi-treatment was beneficial, we still have questions about the exclusive benefits of calcium on its own for constipation.
Read More
8
Magnesium's role in constipation treatment
Effect of magnesium oxide with probiotics on bowel movements in elderly orthopedic patients with chronic constipation: a retrospective chart review.
Magnesium's effects on constipation evaluated
We aimed to understand how magnesium, particularly when combined with probiotics, influences bowel movements in elderly orthopedic patients suffering from chronic constipation. A retrospective chart review allowed us to analyze various patient records, focusing specifically on the treatments they received and the outcomes.

Magnesium is often talked about as a potential remedy for constipation because it can help draw water into the intestines, making it easier to pass stools. However, since our study also involved probiotics, which can also impact gut health, it becomes harder to isolate the specific effects of magnesium alone.

After reviewing the data, we observed that the combination of magnesium and probiotics did not show a significant advantage in improving bowel movements for the patients involved. This indicates that while magnesium may play a supportive role, its effectiveness on constipation could vary depending on individual circumstances and may not be as pronounced when combined with other treatments.

Overall, this study serves as a reminder of the complexity of managing constipation, especially in the elderly population, where multiple factors can come into play.
Read More

User Reviews

USERS' SCORE
Questionable
Based on 23 Reviews
5.9
9.5
Improved digestion
Good product! Unlike other calcium supplements, this one hasn't caused me constipation, which is essential during pregnancy. My digestive system actually feels improved.
9.5
No constipation effect
This is quite effective for me. I take four tablets daily and haven’t experienced constipation, making it a very good product.
9.5
No constipation noticed
The product is excellent! After starting this calcium supplement for my bone density, I haven’t faced any constipation, and my overall wellbeing has improved significantly.
9.5
Helps with constipation
Excellent! Taking just one daily helps me with constipation. I monitor my calcium levels and hope for improvement in my next scan.
9.5
No constipation experienced
This is the best calcium I have ever purchased! Unlike other brands, it doesn’t cause constipation, and I’ve seen significant growth in my nails.
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