5/22/2025
Last update
5/22/2025
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 35 Researches
7.1
USERS' SCORE
Good
Based on 11 Reviews
8
Supplement Facts
Serving Size: 4 Capsules
Serving Per Container: 30
Amount Per Serving
%DV
Vitamin C (from culture of S. cerevisiae)
50 mg
56%
Vitamin D (as D3 from culture of S. cerevisiae)
40 mcg (1,600 IU)
200%
Vitamin K (from culture of S. cerevisiae)
120 mcg
100%
Calcium (naturally occurring from Algae)
1,100 mg
85%
Magnesium (from Algae and Dead Sea minerals)
357 mg
85%
Vitamin K (as K2 MK-7)
50 mcg
+
Strontium (naturally occurring from Algae)
3.8 mg
+
Boron (from Brown Rice Chelate)
3 mg
+
Silica (naturally occurring from Algae)
2.2 mg
+
Vanadium (naturally occurring from Algae)
25 mcg
+
Raw Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, [Lactobacillus bulgaricus, Lactobacillus plantarum] (500 Million CFU).
64 mg
+
Top Medical Research Studies
8
Vitamin D supports bone health
We aimed to uncover the relationship between vitamin D levels and bone mineral density (BMD) in menopausal women, a group particularly vulnerable to osteoporosis due to hormonal changes. To achieve this, we conducted a thorough study involving 32 participants, all of whom were menopausal women without a history of hormone replacement therapy or vitamin D supplementation.
Throughout our research, we measured the participants' serum vitamin D levels and evaluated their bone density using a technique called radiofrequency echographic multi-spectrometry (REMS). Our findings revealed a significant positive correlation between vitamin D levels and BMD—indicating that higher vitamin D levels were associated with better bone density.
This suggests that maintaining adequate vitamin D levels might be crucial for preserving bone health during menopause. Given the particular vulnerability of this demographic to osteoporosis, our study underscores the importance of monitoring and potentially supplementing vitamin D to support bone health in menopausal women.
Overall, we believe our findings contribute to the conversation around menopause management by highlighting the role of vitamin D in promoting healthier bones, and we suggest that REMS could serve as a valuable tool in assessing these changes in postmenopausal women.
Throughout our research, we measured the participants' serum vitamin D levels and evaluated their bone density using a technique called radiofrequency echographic multi-spectrometry (REMS). Our findings revealed a significant positive correlation between vitamin D levels and BMD—indicating that higher vitamin D levels were associated with better bone density.
This suggests that maintaining adequate vitamin D levels might be crucial for preserving bone health during menopause. Given the particular vulnerability of this demographic to osteoporosis, our study underscores the importance of monitoring and potentially supplementing vitamin D to support bone health in menopausal women.
Overall, we believe our findings contribute to the conversation around menopause management by highlighting the role of vitamin D in promoting healthier bones, and we suggest that REMS could serve as a valuable tool in assessing these changes in postmenopausal women.
Read More
8
We explored the potential benefits of low-dose vitamin K2, specifically menaquinone-7 (MK-7), on bone health in healthy postmenopausal women. Over a three-year study with 244 participants, we found that MK-7 significantly improved bone mineral density and strength, suggesting it could mitigate age-related bone loss.
While the results are promising for postmenopausal women, more research is needed to determine if these findings apply to other groups, such as men and children.
While the results are promising for postmenopausal women, more research is needed to determine if these findings apply to other groups, such as men and children.
Read More
3
We examined the impact of vitamin K2, specifically MK-7, on bone health in early menopausal women through a rigorous randomized double-blind placebo-controlled trial.
Over one year, 334 healthy Norwegian women were given either MK-7 supplements or a placebo. Despite reduced levels of certain bone markers, our results showed that vitamin K2 did not actually prevent bone loss in these participants.
This suggests that while vitamin K2 might have some biochemical benefits, it doesn’t significantly improve bone density during menopause.
Over one year, 334 healthy Norwegian women were given either MK-7 supplements or a placebo. Despite reduced levels of certain bone markers, our results showed that vitamin K2 did not actually prevent bone loss in these participants.
This suggests that while vitamin K2 might have some biochemical benefits, it doesn’t significantly improve bone density during menopause.
Read More
Most Useful Reviews
7.5
Pain relief achieved
7 people found this helpful
I love drinking this supplement after menopause. I dealt with pain issues related to menopause at age 51 and tried various supplements. I switched to this low multivitamin after a year, and it has significantly improved my whole-body pain. My daily life has settled down. If you're apprehensive about supplements, I encourage you to try it. The side effects of medication are daunting, and I believe it's vital to invest in your health.
Read More
9
Bone density normalised
2 people found this helpful
I've been taking this supplement for about a year and a half to counteract menopausal hormone deficiency and osteoporosis. Despite not tolerating a prescribed osteoporosis drug, I find this and bone broth effective. I adjusted my intake to prevent magnesium deficiency. After recently measuring my bone density, I'm relieved to see that it's above average for my age group.
Read More
8.5
Effective calcium support
2 people found this helpful
This is possibly the best calcium supplement I’ve found. After searching extensively, I discovered this company’s products have the optimal composition I needed for menopause. Despite the price, the quality justifies it. I take two capsules twice a day and highly recommend it!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 35 Researches
7.1
- All Researches
9
We explored whether vitamin K could play a role in supporting bone health during menopause by studying ovariectomized mice. Through various scientific techniques, we observed that vitamin K treatment significantly improved bone structure and mineral metabolism.
It appeared to enhance bone formation and reduce bone resorption, suggesting it helps maintain stronger bones. However, while the findings are promising for potential treatments in osteopenic patients, the study was conducted on mice and may not directly translate to human health benefits.
It appeared to enhance bone formation and reduce bone resorption, suggesting it helps maintain stronger bones. However, while the findings are promising for potential treatments in osteopenic patients, the study was conducted on mice and may not directly translate to human health benefits.
Read More
9
We examined how the combined use of vitamin D3 and vitamin K2 affects bone mineral density (BMD) in postmenopausal women suffering from osteoporosis. In a study involving ninety-two women, participants were divided into four groups receiving different treatments, with BMD measured over two years.
Results showed that those receiving vitamin D3 and vitamin K2 had significant improvements in their spine BMD compared to a control group taking calcium alone. This suggests that supplementing with both vitamins may be a more beneficial approach for improving bone health during menopause.
Results showed that those receiving vitamin D3 and vitamin K2 had significant improvements in their spine BMD compared to a control group taking calcium alone. This suggests that supplementing with both vitamins may be a more beneficial approach for improving bone health during menopause.
Read More
9
We explored the connection between magnesium deficiency and various challenges commonly faced by postmenopausal women, such as chronic pain, memory decline, and mood disorders. Our research specifically focused on how magnesium supplementation can help in alleviating these issues in ovariectomized and aged female mice—modeling the postmenopausal state.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
Read More
9
Our exploration centered on the effects of magnesium, particularly from nanofiltrated deep ocean water (DOW), in addressing osteoporosis, a common concern during menopause. In our study, we used ovariectomized female Sprague-Dawley rats, a model that simulates menopausal conditions. We administered varying amounts of DOW daily over eight weeks to observe its impact on bone health.
We found that DOW supplementation significantly increased bone density and reduced bone loss related to menopause. This was particularly notable as the rats that received DOW showed improved bone structure and reduced adiposity in their bones. More specifically, the lowest doses of DOW led to increased expression of a key protein called RUNX2, which plays an essential role in the formation of bone cells known as osteoblasts.
In human osteoblasts, DOW also raised levels of osteocalcin and alkaline phosphatase—both vital for promoting bone health. Overall, our findings demonstrated that magnesium-rich DOW can enhance osteoblast differentiation, contributing positively to bone structure integrity during menopause. This work highlights how incorporating magnesium into our diets or supplements could be beneficial for bone health as we age.
We found that DOW supplementation significantly increased bone density and reduced bone loss related to menopause. This was particularly notable as the rats that received DOW showed improved bone structure and reduced adiposity in their bones. More specifically, the lowest doses of DOW led to increased expression of a key protein called RUNX2, which plays an essential role in the formation of bone cells known as osteoblasts.
In human osteoblasts, DOW also raised levels of osteocalcin and alkaline phosphatase—both vital for promoting bone health. Overall, our findings demonstrated that magnesium-rich DOW can enhance osteoblast differentiation, contributing positively to bone structure integrity during menopause. This work highlights how incorporating magnesium into our diets or supplements could be beneficial for bone health as we age.
Read More
9
Isoflavones, probiotics boost bone health
We explored the impact of a novel red clover extract rich in isoflavones and probiotics on bone health in postmenopausal osteopenic women. In a year-long double-blind trial with 78 participants, we compared this treatment alongside standard supplements against a placebo. Results showed that the extract substantially reduced bone mineral density loss and improved certain estrogen metabolism markers. However, it did not affect other bone turnover indicators significantly. Overall, combining the extract with calcium and magnesium proved beneficial for bone health in this demographic.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Pain relief achieved
7 people found this helpful
I love drinking this supplement after menopause. I dealt with pain issues related to menopause at age 51 and tried various supplements. I switched to this low multivitamin after a year, and it has significantly improved my whole-body pain. My daily life has settled down. If you're apprehensive about supplements, I encourage you to try it. The side effects of medication are daunting, and I believe it's vital to invest in your health.
Read More
9
Bone density normalised
2 people found this helpful
I've been taking this supplement for about a year and a half to counteract menopausal hormone deficiency and osteoporosis. Despite not tolerating a prescribed osteoporosis drug, I find this and bone broth effective. I adjusted my intake to prevent magnesium deficiency. After recently measuring my bone density, I'm relieved to see that it's above average for my age group.
Read More
8.5
Effective calcium support
2 people found this helpful
This is possibly the best calcium supplement I’ve found. After searching extensively, I discovered this company’s products have the optimal composition I needed for menopause. Despite the price, the quality justifies it. I take two capsules twice a day and highly recommend it!
Read More
9
Natural ingredients preferred
After a recent health check-up indicated increased osteoporosis due to menopause, I sought a calcium supplement and found this one with excellent reviews. I'm pleased it contains natural raw materials sourced from seaweed, aligning with my preferences.
Read More
7.5
Bone density improved
2 people found this helpful
This product is excellent! My bone density decreased with menopause, and my doctor advised calcium tablets. I chose this supplement for its natural ingredients and comprehensive formula. After two bottles, I no longer experienced constipation, my waist discomfort improved, and my sleep quality has enhanced. I'm eager for my next bone density test results as I believe they will be better. The price is steep, so I hope for more discounts.
Read More
Frequently Asked Questions
6
Energy levels restored
2 people found this helpful
After a month of taking this supplement, I noticed my teeth feel healthier, and my strength improved as I climbed stairs during menopause. Although the pill is a bit large, it’s easy to swallow and absorbed well. I appreciate that it meets my calcium needs with just one softgel daily.
9
Bone density normalised
2 people found this helpful
I've been taking this supplement for about a year and a half to counteract menopausal hormone deficiency and osteoporosis. Despite not tolerating a prescribed osteoporosis drug, I find this and bone broth effective. I adjusted my intake to prevent magnesium deficiency. After recently measuring my bone density, I'm relieved to see that it's above average for my age group.
7.5
Improved osteoporosis condition
2 people found this helpful
I was diagnosed with osteoporosis after menopause and initially took Calamet without improvement. Later, I found Garden of Life, which contains natural calcium, magnesium, strontium, boron, and vitamin K. After using it for a year, my osteoporosis condition has improved.
7.5
Bone density improved
2 people found this helpful
This product is excellent! My bone density decreased with menopause, and my doctor advised calcium tablets. I chose this supplement for its natural ingredients and comprehensive formula. After two bottles, I no longer experienced constipation, my waist discomfort improved, and my sleep quality has enhanced. I'm eager for my next bone density test results as I believe they will be better. The price is steep, so I hope for more discounts.
7.5
Pain relief achieved
7 people found this helpful
I love drinking this supplement after menopause. I dealt with pain issues related to menopause at age 51 and tried various supplements. I switched to this low multivitamin after a year, and it has significantly improved my whole-body pain. My daily life has settled down. If you're apprehensive about supplements, I encourage you to try it. The side effects of medication are daunting, and I believe it's vital to invest in your health.
7.5
Trustworthy supplement
It’s an organic garden of life product that I can trust and consume. As someone in my mid-50s experiencing a couple of physical symptoms of menopause, I believe that calcium, magnesium, and other food intake will suffice with just two pills a day.
7.5
Calcium intake sufficient
As I entered menopause, I began taking calcium supplements, believing I would become deficient. With 800mg daily, I take three tablets as they contain magnesium and other beneficial ingredients. I plan to continue this regimen.
8.5
Effective calcium support
2 people found this helpful
This is possibly the best calcium supplement I’ve found. After searching extensively, I discovered this company’s products have the optimal composition I needed for menopause. Despite the price, the quality justifies it. I take two capsules twice a day and highly recommend it!
8
Calcium maltobionate supports bone health
We conducted a study to investigate how calcium maltobionate affects bone density in healthy Japanese women, particularly focusing on those who are pre- and post-menopausal. In a well-structured trial, 48 women aged between 30 and 69 were randomly divided into two groups: one received calcium maltobionate tablets while the other took a placebo designed to mimic the calcium content.
Over 24 weeks, we measured changes in facial and calcaneal bone density along with bone resorption markers. Our results indicated that facial bone mineral density declines more rapidly than that of other areas like the lumbar spine. Importantly, we observed that continuous intake of calcium maltobionate helped to slow down this decline in bone density for women in both menopausal stages, suggesting its potential role in osteoporosis prevention.
Overall, we found that facial bone mineral density may serve as an important indicator of bone health in middle-aged women. While our study highlights the beneficial aspects of calcium maltobionate, it’s essential to note that the individual effects of calcium itself could not be isolated from the compound used in the treatment.
Over 24 weeks, we measured changes in facial and calcaneal bone density along with bone resorption markers. Our results indicated that facial bone mineral density declines more rapidly than that of other areas like the lumbar spine. Importantly, we observed that continuous intake of calcium maltobionate helped to slow down this decline in bone density for women in both menopausal stages, suggesting its potential role in osteoporosis prevention.
Overall, we found that facial bone mineral density may serve as an important indicator of bone health in middle-aged women. While our study highlights the beneficial aspects of calcium maltobionate, it’s essential to note that the individual effects of calcium itself could not be isolated from the compound used in the treatment.
8
Vitamin D supports bone health
We aimed to uncover the relationship between vitamin D levels and bone mineral density (BMD) in menopausal women, a group particularly vulnerable to osteoporosis due to hormonal changes. To achieve this, we conducted a thorough study involving 32 participants, all of whom were menopausal women without a history of hormone replacement therapy or vitamin D supplementation.
Throughout our research, we measured the participants' serum vitamin D levels and evaluated their bone density using a technique called radiofrequency echographic multi-spectrometry (REMS). Our findings revealed a significant positive correlation between vitamin D levels and BMD—indicating that higher vitamin D levels were associated with better bone density.
This suggests that maintaining adequate vitamin D levels might be crucial for preserving bone health during menopause. Given the particular vulnerability of this demographic to osteoporosis, our study underscores the importance of monitoring and potentially supplementing vitamin D to support bone health in menopausal women.
Overall, we believe our findings contribute to the conversation around menopause management by highlighting the role of vitamin D in promoting healthier bones, and we suggest that REMS could serve as a valuable tool in assessing these changes in postmenopausal women.
Throughout our research, we measured the participants' serum vitamin D levels and evaluated their bone density using a technique called radiofrequency echographic multi-spectrometry (REMS). Our findings revealed a significant positive correlation between vitamin D levels and BMD—indicating that higher vitamin D levels were associated with better bone density.
This suggests that maintaining adequate vitamin D levels might be crucial for preserving bone health during menopause. Given the particular vulnerability of this demographic to osteoporosis, our study underscores the importance of monitoring and potentially supplementing vitamin D to support bone health in menopausal women.
Overall, we believe our findings contribute to the conversation around menopause management by highlighting the role of vitamin D in promoting healthier bones, and we suggest that REMS could serve as a valuable tool in assessing these changes in postmenopausal women.
9
We explored the effects of a nutraceutical blend, including magnesium, on menopause symptoms through a crossover trial involving 43 postmenopausal women.
Participants experienced significant reductions in menopause symptoms, as measured by the Menopause Rating Scale, after using the nutraceuticals.
Additionally, improvements were noted in cardiovascular risk factors, such as lower cholesterol levels and blood pressure.
Overall, this study suggests that magnesium, combined with other nutrients, may provide meaningful relief for postmenopausal symptoms.
Participants experienced significant reductions in menopause symptoms, as measured by the Menopause Rating Scale, after using the nutraceuticals.
Additionally, improvements were noted in cardiovascular risk factors, such as lower cholesterol levels and blood pressure.
Overall, this study suggests that magnesium, combined with other nutrients, may provide meaningful relief for postmenopausal symptoms.
References
- Suehiro D, Ikeda N, Hirooka K, Ihara A, Fukami K, et al. Decrease in Facial Bone Density with Aging and Maintenance Effect of Calcium Maltobionate Ingestion in Japanese Adult Women: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trial. Nutrients. 2025;17. 10.3390/nu17020262
- Hou J, Mao H, Xie P, Cui Y, Rong M. The effect of different traditional Chinese exercises on bone mineral density in menopausal women: a systematic review and network meta-analysis. Front Public Health. 2024;12:1430608. 10.3389/fpubh.2024.1430608
- Zhang SB, Yang J, Xu HW, Yi YY, Ren CX, et al. Association Between 25-hydroxyvitamin D Status and New Vertebral Fractures Post Percutaneous Vertebral Augmentation in Patients During Postmenopause: A Retrospective Case-control Study. Pain Physician. 2025;28:E31.
- Binkley N, Sempos CT, Borchardt G, Larsen J, Stacey ML, et al. Association of standardized serum 25-hydroxyvitamin D with falls in post-menopausal women. Osteoporos Int. 2025;36:255. 10.1007/s00198-024-07310-2
- Cocetta V, Zorzi M, Bejor S, Cesta MC, De Pizzol M, et al. Retrospective Analysis of the Effect of Postmenopausal Women Medications on SARS-CoV-2 Infection Progression. Life (Basel). 2024;14. 10.3390/life14091107
- Bowles SD, Jacques R, Hill TR, Eastell R, Walsh JS. Effects of High Dose Bolus Cholecalciferol on Free Vitamin D Metabolites, Bone Turnover Markers and Physical Function. Nutrients. 2024;16. 10.3390/nu16172888
- Korkmaz H, Pehlivanoğlu B. Is Vitamin D a Crucial Molecule for Musculoskeletal and Cardiovascular Systems in Postmenopausal Women?. Front Biosci (Landmark Ed). 2024;29:281. 10.31083/j.fbl2908281
- Rusu ME, Bigman G, Ryan AS, Popa DS. Investigating the Effects and Mechanisms of Combined Vitamin D and K Supplementation in Postmenopausal Women: An Up-to-Date Comprehensive Review of Clinical Studies. Nutrients. 2024;16. 10.3390/nu16142356
- Occhiuto M, Pepe J, Colangelo L, Lucarelli M, Angeloni A, et al. Effect of 2 Years of Monthly Calcifediol Administration in Postmenopausal Women with Vitamin D Insufficiency. Nutrients. 2024;16. 10.3390/nu16111754
- G Siregar MF, Jabbar F, Effendi IH, Alhair T, Prabudi MO, et al. Correlation between serum vitamin D levels and bone mass density evaluated by radiofrequency echographic multi-spectrometry technology (REMS) in menopausal women. Narra J. 2024;4:e452. 10.52225/narra.v4i1.452
- Joo NS, Shin SH, Kim KN, Lee SH, Jung S, et al. Home Meal Replacement Fortified with Eggshell Powder and Vitamin D Prevents Bone Loss in Postmenopausal Women: A Randomized, Double-Blind, Controlled Study. Nutrients. 2024;16. 10.3390/nu16081152
- de Vries F, Bittner R, Maresz K, Machuron F, Gåserød O, et al. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women. Nutrients. 2025;17. 10.3390/nu17050815
- Tanaka N, Arima K, Nishimura T, Tomita Y, Mizukami S, et al. Vitamin K deficiency, evaluated with higher serum ucOC, was correlated with poor bone status in women. J Physiol Anthropol. 2020;39:9. 10.1186/s40101-020-00221-1
- Rangel LBA, de Siqueira D, Soares ODR, Santana HS, Miguel EC, et al. Vitamin K Supplementation Modulates Bone Metabolism and Ultra-Structure of Ovariectomized Mice. Cell Physiol Biochem. 2018;51:356. 10.1159/000495234
- Jaghsi S, Hammoud T, Haddad S. Relation Between Circulating Vitamin K1 and Osteoporosis in the Lumbar Spine in Syrian Post-Menopausal Women. Open Rheumatol J. 2018;12:1. 10.2174/1874312901812010001
- Vignini A, Nanetti L, Raffaelli F, Sabbatinelli J, Salvolini E, et al. Effect of 1-y oral supplementation with vitaminized olive oil on platelets from healthy postmenopausal women. Nutrition. 2017;42:92. 10.1016/j.nut.2017.06.013
- Villa JKD, Diaz MAN, Pizziolo VR, Martino HSD. Effect of vitamin K in bone metabolism and vascular calcification: A review of mechanisms of action and evidences. Crit Rev Food Sci Nutr. 2017;57:3959. 10.1080/10408398.2016.1211616
- Guralp O, Erel CT. Effects of vitamin K in postmenopausal women: mini review. Maturitas. 2014;77:294. 10.1016/j.maturitas.2013.11.002
- Knapen MH, Drummen NE, Smit E, Vermeer C, Theuwissen E. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women. Osteoporos Int. 2013;24:2499. 10.1007/s00198-013-2325-6
- Borrelli F, Ernst E. Alternative and complementary therapies for the menopause. Maturitas. 2010;66:333. 10.1016/j.maturitas.2010.05.010
- Emaus N, Gjesdal CG, Almås B, Christensen M, Grimsgaard AS, et al. Vitamin K2 supplementation does not influence bone loss in early menopausal women: a randomised double-blind placebo-controlled trial. Osteoporos Int. 2010;21:1731. 10.1007/s00198-009-1126-4
- Yasui T, Uemura H, Tomita J, Miyatani Y, Yamada M, et al. Association of serum undercarboxylated osteocalcin with serum estradiol in pre-, peri- and early post-menopausal women. J Endocrinol Invest. 2006;29:913.
- Katsuyama H, Ideguchi S, Fukunaga M, Fukunaga T, Saijoh K, et al. Promotion of bone formation by fermented soybean (Natto) intake in premenopausal women. J Nutr Sci Vitaminol (Tokyo). 2004;50:114.
- Booth SL, Broe KE, Gagnon DR, Tucker KL, Hannan MT, et al. Vitamin K intake and bone mineral density in women and men. Am J Clin Nutr. 2003;77:512.
- Iwamoto J, Takeda T, Ichimura S. Effect of menatetrenone on bone mineral density and incidence of vertebral fractures in postmenopausal women with osteoporosis: a comparison with the effect of etidronate. J Orthop Sci. 2001;6:487.
- Iwamoto J, Takeda T, Ichimura S. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis. J Orthop Sci. 2000;5:546.
- Iwamoto I, Kosha S, Noguchi S, Murakami M, Fujino T, et al. A longitudinal study of the effect of vitamin K2 on bone mineral density in postmenopausal women a comparative study with vitamin D3 and estrogen-progestin therapy. Maturitas. 1999;31:161.
- Atteia HH, Ahmed SF, Askar ME, Sakr AT. Utilizing a Combination of Supplements Comprising Boric Acid, Magnesium, Vitamin D3, and Extra Virgin Olive Oil to Improve Metabolism in Menopausal Ovariectomized Rats. Biol Trace Elem Res. 2024. 10.1007/s12011-024-04476-y
- Zhang J, Mai CL, Xiong Y, Lin ZJ, Jie YT, et al. The Causal Role of Magnesium Deficiency in the Neuroinflammation, Pain Hypersensitivity and Memory/Emotional Deficits in Ovariectomized and Aged Female Mice. J Inflamm Res. 2021;14:6633. 10.2147/JIR.S330894
- Chen PC, Lee YC, Jao HY, Wang CP, Jacobs A, et al. Supplementation of nanofiltrated deep ocean water ameliorate the progression of osteoporosis in ovariectomized rat via regulating osteoblast differentiation. J Food Biochem. 2020;44:e13236. 10.1111/jfbc.13236
- Kolanu BR, Vadakedath S, Boddula V, Kandi V. Activities of Serum Magnesium and Thyroid Hormones in Pre-, Peri-, and Post-menopausal Women. Cureus. 2020;12:e6554. 10.7759/cureus.6554
- Wright HH, Kruger MC, Schutte WD, Wentzel-Viljoen E, Kruger IM, et al. Magnesium Intake Predicts Bone Turnover in Postmenopausal Black South African Women. Nutrients. 2019;11. 10.3390/nu11102519
- Lambert MNT, Thybo CB, Lykkeboe S, Rasmussen LM, Frette X, et al. Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial. Am J Clin Nutr. 2017;106:909. 10.3945/ajcn.117.153353
- McCabe D, Lisy K, Lockwood C, Colbeck M. The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a systematic review. JBI Database System Rev Implement Rep. 2017;15:402. 10.11124/JBISRIR-2016-002965
- Trimarco V, Rozza F, Izzo R, De Leo V, Cappelli V, et al. Effects of a new combination of nutraceuticals on postmenopausal symptoms and metabolic profile: a crossover, randomized, double-blind trial. Int J Womens Health. 2016;8:581.
