We investigated if small extracellular vesicles (sEVs) derived from tonsil stem cells could improve myo-inositol production, which is often disrupted by inflammation in menopausal women.
Over two weeks, mice received treatments mimicking this condition. Our results indicated that those receiving sEVs showed a restoration of myo-inositol levels and healthier muscle profiles compared to those that did not.
This research suggests that sEVs could be a promising option to improve metabolic health during menopause.
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7
Folate impacts bone health in menopause
Relation of folates, vitamin B12 and homocysteine to vertebral bone mineral density change in postmenopausal women. A five-year longitudinal evaluation.
We sought to understand how vitamin B levels influence bone health in postmenopausal women. Our analysis of 117 women over five years showed that higher folate levels positively correlate with vertebral bone mineral density changes.
However, we found no significant link between changes in bone density and either homocysteine or vitamin B12 levels. This suggests that folate deficiency may play a significant role in bone health during menopause, indicating its importance for maintaining vertebral strength.
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9
Effective nutritional menopause treatment
Improvement in menopausal symptoms with a nutritional product containing evening primrose oil, hop extract, saffron, tryptophan, vitamins B6, D3, K2, B12, and B9.
We explored the effects of Exelvit Menopause®, a nutritional product incorporating various ingredients including vitamins and herbal extracts, on menopausal symptoms. Over 12 weeks, 156 menopausal women took this supplement daily, and we measured symptom relief using a standardized score.
Our findings revealed a noteworthy decrease in symptoms such as hot flashes, sleep disturbances, and irritability, with reductions ranging from 27.8% to 48.15%. This suggests that Exelvit Menopause® could offer a promising, non-hormonal approach to easing menopause-related discomfort.
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Most Useful Reviews
7.5
Relieves menopause symptoms
7 people found this helpful
One of the best!!!💕 These vitamins truly work, with excellent dosages! The capsules are sizable, requiring a dose of 2 per day, and a jar lasts for a month. This is, perhaps, the finest B complex available for order in Russia. I consistently purchase it for my mother as it alleviates her menopause symptoms. Generally, B vitamins are vital for everyone, especially women during PMS, pregnancy, and breastfeeding. Deficiencies can lead to issues such as anemia, cracking at the corners of the lips, stomatitis, poor wound healing, irritability, fatigue, and decreased appetite. Blood tests can help determine deficiencies, and it is advisable to take vitamins as prescribed by a doctor according to your individual needs. Wishing good health to all!😊🙏🏻
Improvement in menopausal symptoms with a nutritional product containing evening primrose oil, hop extract, saffron, tryptophan, vitamins B6, D3, K2, B12, and B9.
We explored the effects of Exelvit Menopause®, a nutritional product incorporating various ingredients including vitamins and herbal extracts, on menopausal symptoms. Over 12 weeks, 156 menopausal women took this supplement daily, and we measured symptom relief using a standardized score.
Our findings revealed a noteworthy decrease in symptoms such as hot flashes, sleep disturbances, and irritability, with reductions ranging from 27.8% to 48.15%. This suggests that Exelvit Menopause® could offer a promising, non-hormonal approach to easing menopause-related discomfort.
Read More
9
Vitamin B12 improves menopausal dry eyes
Efficacy of hyaluronic acid 0.3%, cyanocobalamin, electrolytes, and P-Plus in menopause patients with moderate dry eye disease.
We examined whether a combination of hyaluronic acid 0.3% and vitamin B12 could improve dry eye symptoms in menopausal women. In a study involving thirty women, we measured the effectiveness of a specially formulated eye drop containing these ingredients over a 30-day period.
After treatment, patients reported decreased symptoms and increased tear stability. Their scores on established dry eye assessment tools showed significant improvements, indicating that vitamin B12, alongside other ingredients, may play a beneficial role in alleviating dry eye issues during menopause.
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8
Vitamin B may ease perimenopause
Clinical Evaluation of Effectiveness and Safety of Combined Use of Dietary Supplements Amberen and Smart B in Women with Climacteric Syndrome in Perimenopause.
This randomized, double-blind, placebo-controlled study explored how a combination of the Amberen supplement and a vitamin B complex affects women in perimenopause suffering from climacteric symptoms.
We found that this dietary supplement is not only safe but also helps alleviate various symptoms like hot flashes and mood swings. Participants experienced improved sleep, cognitive function, and overall well-being.
Overall, this suggests that vitamin B complex can be a valuable part of managing perimenopausal symptoms.
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8
Vitamin-enriched oil beneficial for menopause
Effect of 1-y oral supplementation with vitaminized olive oil on platelets from healthy postmenopausal women.
We investigated the impact of vitamin-enriched extra virgin olive oil on postmenopausal women's health. In a year-long study involving 60 participants, half received the enriched oil while the other half got a placebo.
We found that those taking the vitamin-enriched olive oil showed improved platelet function and reduced levels of harmful nitrosative stress markers in their blood. This suggests that incorporating this healthy fat into our diets could help manage health issues related to menopause, particularly those affecting bone health.
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7
Investigating T-MSCs for menopause
Tonsil-Derived Mesenchymal Stem Cell-Derived Small Extracellular Vesicles (sEVs) Restore Myo-Inositol Production in LPS-Treated Skeletal Muscle.
We investigated if small extracellular vesicles (sEVs) derived from tonsil stem cells could improve myo-inositol production, which is often disrupted by inflammation in menopausal women.
Over two weeks, mice received treatments mimicking this condition. Our results indicated that those receiving sEVs showed a restoration of myo-inositol levels and healthier muscle profiles compared to those that did not.
This research suggests that sEVs could be a promising option to improve metabolic health during menopause.
One of the best!!!💕 These vitamins truly work, with excellent dosages! The capsules are sizable, requiring a dose of 2 per day, and a jar lasts for a month. This is, perhaps, the finest B complex available for order in Russia. I consistently purchase it for my mother as it alleviates her menopause symptoms. Generally, B vitamins are vital for everyone, especially women during PMS, pregnancy, and breastfeeding. Deficiencies can lead to issues such as anemia, cracking at the corners of the lips, stomatitis, poor wound healing, irritability, fatigue, and decreased appetite. Blood tests can help determine deficiencies, and it is advisable to take vitamins as prescribed by a doctor according to your individual needs. Wishing good health to all!😊🙏🏻
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
Cho KA, Kim YH, Woo SY, Ryu KH. Tonsil-Derived Mesenchymal Stem Cell-Derived Small Extracellular Vesicles (sEVs) Restore Myo-Inositol Production in LPS-Treated Skeletal Muscle. Tissue Eng Regen Med. 2025. 10.1007/s13770-025-00709-w
Kachko VA, Shulman LP, Kuznetsova IV, Uspenskaya YB, Burchakov DI. Clinical Evaluation of Effectiveness and Safety of Combined Use of Dietary Supplements Amberen and Smart B in Women with Climacteric Syndrome in Perimenopause. Adv Ther. 2024;41:3183. 10.1007/s12325-024-02910-0
Palacios S, Mustata C, Rizo JM, Regidor PA. Improvement in menopausal symptoms with a nutritional product containing evening primrose oil, hop extract, saffron, tryptophan, vitamins B6, D3, K2, B12, and B9. Eur Rev Med Pharmacol Sci. 2023;27:8180. 10.26355/eurrev_202309_33578
De-Hita-Cantalejo C, Sánchez-González MC, Silva-Viguera C, García-Romera MC, Feria-Mantero R, et al. Efficacy of hyaluronic acid 0.3%, cyanocobalamin, electrolytes, and P-Plus in menopause patients with moderate dry eye disease. Graefes Arch Clin Exp Ophthalmol. 2022;260:529. 10.1007/s00417-021-05415-6
Odai T, Terauchi M, Suzuki R, Kato K, Hirose A, et al. Depressive Symptoms in Middle-Aged and Elderly Women Are Associated with a Low Intake of Vitamin B6: A Cross-Sectional Study. Nutrients. 2020;12. 10.3390/nu12113437
Vignini A, Nanetti L, Raffaelli F, Sabbatinelli J, Salvolini E, et al. Effect of 1-y oral supplementation with vitaminized olive oil on platelets from healthy postmenopausal women. Nutrition. 2017;42:92. 10.1016/j.nut.2017.06.013
McCabe D, Lisy K, Lockwood C, Colbeck M. The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a systematic review. JBI Database System Rev Implement Rep. 2017;15:402. 10.11124/JBISRIR-2016-002965
Cagnacci A, Bagni B, Zini A, Cannoletta M, Generali M, et al. Relation of folates, vitamin B12 and homocysteine to vertebral bone mineral density change in postmenopausal women. A five-year longitudinal evaluation. Bone. 2008;42:314. 10.1016/j.bone.2007.10.022